GTPBP10 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GTPBP10
Entrez Gene ID	85865
Full Name	GTP binding protein 10
Synonyms	ObgH2,UG0751c10
General protein information	Preferred Names GTP binding protein 10 Names GTP-binding protein 10 GTP binding protein 10 (putative) protein obg homolog 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q21.13
Summary	Small G proteins, such as GTPBP10, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610920

mRNA and Protein(s)

mRNA	Protein	Name
NM_033107.3	NP_149098.2	GTP-binding protein 10 isoform 2
NM_033107.4	NP_149098.2	GTP-binding protein 10 isoform 2
NM_001042717.2	NP_001036182.1	GTP-binding protein 10 isoform 1
NM_001042717.3	NP_001036182.1	GTP-binding protein 10 isoform 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	GTPBP10	NP_001073783.1
Gallus gallus (chicken)	GTPBP10	XP_004939336.1
Xenopus tropicalis (tropical clawed frog)	gtpbp10	NP_001011239.1
Danio rerio (zebrafish)	gtpbp10	NP_001002454.1
Drosophila melanogaster (fruit fly)	CG10628	NP_609999.2
Pan troglodytes (chimpanzee)	GTPBP10	XP_519187.2
	GTPBP10	XP_001092504.1
Canis lupus familiaris (dog)	GTPBP10	XP_003431907.1
Rattus norvegicus (Norway rat)	Gtpbp10	NP_001094285.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008337	XP_317120.3
Caenorhabditis elegans (roundworm)	C26E6.12	NP_498042.1
Homo sapiens (human)	GTPBP10	NP_149098.2
Mus musculus (house mouse)	Gtpbp10	NP_694756.1

Gene Ontology
Bibliography

Related articles in PubMed

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.
van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, M?larstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, Clarke RJ, Dehghan A, Erdmann J, Ferrucci L, Hamsten A, Hofman A, Hunter DJ, Goel A, Johnson AD, Kathiresan S, Kampman E, Kiel DP, Kiemeney LA, Chambers JC, Kraft P, Lindemans J, McKnight B, Nelson CP, O'Donnell CJ, Psaty BM, Ridker PM, Rivadeneira F, Rose LM, Seedorf U, Siscovick DS, Schunkert H, Selhub J, Ueland PM, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Witteman JC, den Heijer M, Jacques P, Uitterlinden AG, Kooner JS, Rader DJ, Reilly MP, Mooser V, Chasman DI, Samani NJ, Ahmadi KR
The American journal of clinical nutrition98(3)668-76(2013 Sep)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.
Denoeud F, Kapranov P, Ucla C, Frankish A, Castelo R, Drenkow J, Lagarde J, Alioto T, Manzano C, Chrast J, Dike S, Wyss C, Henrichsen CN, Holroyd N, Dickson MC, Taylor R, Hance Z, Foissac S, Myers RM, Rogers J, Hubbard T, Harrow J, Guig? R, Gingeras TR, Antonarakis SE, Reymond A
Genome research17(6)746-59(2007 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Knock-down of ObgH1 by RNAi induced mitochondria elongation, whereas knock-down of ObgH2 resulted in the disorganization of the nucleolar architecture.
Title: Human small G proteins, ObgH1, and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures.

The following GTPBP10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GTPBP10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu11433	NM_033107.4 Latest version!	Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu12695	NM_001042717.3 Latest version!	Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
View Old Accession Versions >>
OHu11433	NM_033107.3	Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu12695	NM_001042717.2	Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GTPBP10 ( NM_033107.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_149098.2 Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11433
Clone ID Related Accession (Same CDS sequence)	NM_033107.3 , NM_033107.4
Accession Version	NM_033107.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	GTP-binding protein 10 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC002064.1, AC006153.2, AK294325.1, AK095561.1, AK125553.1 and T65158.1. On Jun 2, 2019 this sequence version replaced NM_033107.3. Transcript Variant: This variant (2) represents the longer transcript and it encodes the longer protein (isoform 2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.157525.1, SRR1803611.57067.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGCATT GCAGTTGCGT GTTGTTCAGA AAGTATGGAA ATTTCATCGA TAAGCTAAGA 
CTCTTCACCA GGGGAGGATC CGGTGGAATG GGTTATCCTC GTTTAGGTGG AGAAGGTGGA 
AAAGGTGGTG ATGTCTGGGT TGTAGCCCAG AACAGAATGA CTTTAAAACA ACTTAAAGAC 
AGGTATCCTC GGAAACGGTT TGTGGCTGGA GTAGGAGCAA ACAGCAAAAT TAGTGCACTG 
AAAGGCTCCA AAGGAAAAGA CTGTGAAATC CCTGTGCCTG TGGGTATTTC AGTAACTGAT 
GAAAATGGTA AAATTATAGG AGAACTCAAT AAAGAAAATG ACAGAATTTT GGTAGCTCAA 
GGAGGTCTTG GTGGTAAATT ACTTACAAAT TTCTTACCAT TGAAAGGCCA GAAACGAATA 
ATTCACCTTG ATCTAAAACT TATAGCTGAT GTAGGCCTAG TAGGATTCCC AAATGCTGGA 
AAATCCTCTT TGCTAAGTTG TGTTTCTCAT GCAAAACCTG CAATTGCAGA TTACGCATTT 
ACAACATTAA AGCCTGAACT TGGAAAGATA ATGTACAGTG ATTTCAAACA GATATCAGTA 
GCTGATCTTC CGGGTTTAAT AGAAGGAGCA CATATGAACA AAGGAATGGG CCACAAATTC 
CTCAAGCATA TAGAAAGAAC TAGACAACTA CTTTTTGTTG TTGATATTTC TGGATTTCAG 
CTTTCTTCTC ACACTCAATA CAGGACAGCT TTTGAAACCA TAATACTGCT TACAAAAGAG 
TTGGAATTGT ACAAAGAGGA ACTTCAGACA AAACCTGCAC TCTTGGCAGT TAATAAAATG 
GACTTGCCAG ATGCCCAAGA TAAGTTCCAT GAATTGATGA GCCAGCTCCA GAATCCTAAA 
GATTTTCTGC ATTTATTTGA AAAAAACATG ATTCCAGAGA GGACTGTAGA GTTCCAACAT 
ATCATCCCCA TATCTGCAGT TACTGGAGAA GGAATCGAAG AATTAAAGAA TTGTATAAGA 
AAGTCACTGG ATGAACAGGC CAACCAGGAA AATGATGCAC TTCATAAGAA ACAGTTGCTT 
AATTTGTGGA TTTCTGATAC AATGTCTTCT ACTGAGCCAC CATCAAAGCA TGCTGTTACT 
ACTTCCAAAA TGGATATAAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149098.2
CDS	27..1190
Translation	MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII

Target ORF information:

RefSeq Version	NM_033107.4
Organism	Homo sapiens(human)
Definition	Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033107.4

ORF Insert Sequence:

ATGGTGCATT GCAGTTGCGT GTTGTTCAGA AAGTATGGAA ATTTCATCGA TAAGCTAAGA 
CTCTTCACCA GGGGAGGATC CGGTGGAATG GGTTATCCTC GTTTAGGTGG AGAAGGTGGA 
AAAGGTGGTG ATGTCTGGGT TGTAGCCCAG AACAGAATGA CTTTAAAACA ACTTAAAGAC 
AGGTATCCTC GGAAACGGTT TGTGGCTGGA GTAGGAGCAA ACAGCAAAAT TAGTGCACTG 
AAAGGCTCCA AAGGAAAAGA CTGTGAAATC CCTGTGCCTG TGGGTATTTC AGTAACTGAT 
GAAAATGGTA AAATTATAGG AGAACTCAAT AAAGAAAATG ACAGAATTTT GGTAGCTCAA 
GGAGGTCTTG GTGGTAAATT ACTTACAAAT TTCTTACCAT TGAAAGGCCA GAAACGAATA 
ATTCACCTTG ATCTAAAACT TATAGCTGAT GTAGGCCTAG TAGGATTCCC AAATGCTGGA 
AAATCCTCTT TGCTAAGTTG TGTTTCTCAT GCAAAACCTG CAATTGCAGA TTACGCATTT 
ACAACATTAA AGCCTGAACT TGGAAAGATA ATGTACAGTG ATTTCAAACA GATATCAGTA 
GCTGATCTTC CGGGTTTAAT AGAAGGAGCA CATATGAACA AAGGAATGGG CCACAAATTC 
CTCAAGCATA TAGAAAGAAC TAGACAACTA CTTTTTGTTG TTGATATTTC TGGATTTCAG 
CTTTCTTCTC ACACTCAATA CAGGACAGCT TTTGAAACCA TAATACTGCT TACAAAAGAG 
TTGGAATTGT ACAAAGAGGA ACTTCAGACA AAACCTGCAC TCTTGGCAGT TAATAAAATG 
GACTTGCCAG ATGCCCAAGA TAAGTTCCAT GAATTGATGA GCCAGCTCCA GAATCCTAAA 
GATTTTCTGC ATTTATTTGA AAAAAACATG ATTCCAGAGA GGACTGTAGA GTTCCAACAT 
ATCATCCCCA TATCTGCAGT TACTGGAGAA GGAATCGAAG AATTAAAGAA TTGTATAAGA 
AAGTCACTGG ATGAACAGGC CAACCAGGAA AATGATGCAC TTCATAAGAA ACAGTTGCTT 
AATTTGTGGA TTTCTGATAC AATGTCTTCT ACTGAGCCAC CATCAAAGCA TGCTGTTACT 
ACTTCCAAAA TGGATATAAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GTPBP10 ( NM_033107.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_149098.2 Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu11433
Clone ID Related Accession (Same CDS sequence)	NM_033107.3 , NM_033107.4
Accession Version	NM_033107.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1164bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-14
Organism	Homo sapiens(human)
Product	GTP-binding protein 10 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF351613.1, AK095561.1, AC002064.1, AC006153.2, AK294325.1, AK125553.1 and T65158.1. On Dec 9, 2010 this sequence version replaced NM_033107.2. Transcript Variant: This variant (2) represents the longer transcript and it encodes the longer protein (isoform 2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.57067.1, SRR1660807.157525.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCATT GCAGTTGCGT GTTGTTCAGA AAGTATGGAA ATTTCATCGA TAAGCTAAGA 
CTCTTCACCA GGGGAGGATC CGGTGGAATG GGTTATCCTC GTTTAGGTGG AGAAGGTGGA 
AAAGGTGGTG ATGTCTGGGT TGTAGCCCAG AACAGAATGA CTTTAAAACA ACTTAAAGAC 
AGGTATCCTC GGAAACGGTT TGTGGCTGGA GTAGGAGCAA ACAGCAAAAT TAGTGCACTG 
AAAGGCTCCA AAGGAAAAGA CTGTGAAATC CCTGTGCCTG TGGGTATTTC AGTAACTGAT 
GAAAATGGTA AAATTATAGG AGAACTCAAT AAAGAAAATG ACAGAATTTT GGTAGCTCAA 
GGAGGTCTTG GTGGTAAATT ACTTACAAAT TTCTTACCAT TGAAAGGCCA GAAACGAATA 
ATTCACCTTG ATCTAAAACT TATAGCTGAT GTAGGCCTAG TAGGATTCCC AAATGCTGGA 
AAATCCTCTT TGCTAAGTTG TGTTTCTCAT GCAAAACCTG CAATTGCAGA TTACGCATTT 
ACAACATTAA AGCCTGAACT TGGAAAGATA ATGTACAGTG ATTTCAAACA GATATCAGTA 
GCTGATCTTC CGGGTTTAAT AGAAGGAGCA CATATGAACA AAGGAATGGG CCACAAATTC 
CTCAAGCATA TAGAAAGAAC TAGACAACTA CTTTTTGTTG TTGATATTTC TGGATTTCAG 
CTTTCTTCTC ACACTCAATA CAGGACAGCT TTTGAAACCA TAATACTGCT TACAAAAGAG 
TTGGAATTGT ACAAAGAGGA ACTTCAGACA AAACCTGCAC TCTTGGCAGT TAATAAAATG 
GACTTGCCAG ATGCCCAAGA TAAGTTCCAT GAATTGATGA GCCAGCTCCA GAATCCTAAA 
GATTTTCTGC ATTTATTTGA AAAAAACATG ATTCCAGAGA GGACTGTAGA GTTCCAACAT 
ATCATCCCCA TATCTGCAGT TACTGGAGAA GGAATCGAAG AATTAAAGAA TTGTATAAGA 
AAGTCACTGG ATGAACAGGC CAACCAGGAA AATGATGCAC TTCATAAGAA ACAGTTGCTT 
AATTTGTGGA TTTCTGATAC AATGTCTTCT ACTGAGCCAC CATCAAAGCA TGCTGTTACT 
ACTTCCAAAA TGGATATAAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149098.2
CDS	78..1241
Translation	MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKISALKGSKGKDCEIPVPVGISVTDENGKIIGELNKENDRILVAQGGLGGKLLTNFLPLKGQKRIIHLDLKLIADVGLVGFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII

Target ORF information:

RefSeq Version	NM_033107.3
Organism	Homo sapiens(human)
Definition	Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033107.3

ORF Insert Sequence:

ATGGTGCATT GCAGTTGCGT GTTGTTCAGA AAGTATGGAA ATTTCATCGA TAAGCTAAGA 
CTCTTCACCA GGGGAGGATC CGGTGGAATG GGTTATCCTC GTTTAGGTGG AGAAGGTGGA 
AAAGGTGGTG ATGTCTGGGT TGTAGCCCAG AACAGAATGA CTTTAAAACA ACTTAAAGAC 
AGGTATCCTC GGAAACGGTT TGTGGCTGGA GTAGGAGCAA ACAGCAAAAT TAGTGCACTG 
AAAGGCTCCA AAGGAAAAGA CTGTGAAATC CCTGTGCCTG TGGGTATTTC AGTAACTGAT 
GAAAATGGTA AAATTATAGG AGAACTCAAT AAAGAAAATG ACAGAATTTT GGTAGCTCAA 
GGAGGTCTTG GTGGTAAATT ACTTACAAAT TTCTTACCAT TGAAAGGCCA GAAACGAATA 
ATTCACCTTG ATCTAAAACT TATAGCTGAT GTAGGCCTAG TAGGATTCCC AAATGCTGGA 
AAATCCTCTT TGCTAAGTTG TGTTTCTCAT GCAAAACCTG CAATTGCAGA TTACGCATTT 
ACAACATTAA AGCCTGAACT TGGAAAGATA ATGTACAGTG ATTTCAAACA GATATCAGTA 
GCTGATCTTC CGGGTTTAAT AGAAGGAGCA CATATGAACA AAGGAATGGG CCACAAATTC 
CTCAAGCATA TAGAAAGAAC TAGACAACTA CTTTTTGTTG TTGATATTTC TGGATTTCAG 
CTTTCTTCTC ACACTCAATA CAGGACAGCT TTTGAAACCA TAATACTGCT TACAAAAGAG 
TTGGAATTGT ACAAAGAGGA ACTTCAGACA AAACCTGCAC TCTTGGCAGT TAATAAAATG 
GACTTGCCAG ATGCCCAAGA TAAGTTCCAT GAATTGATGA GCCAGCTCCA GAATCCTAAA 
GATTTTCTGC ATTTATTTGA AAAAAACATG ATTCCAGAGA GGACTGTAGA GTTCCAACAT 
ATCATCCCCA TATCTGCAGT TACTGGAGAA GGAATCGAAG AATTAAAGAA TTGTATAAGA 
AAGTCACTGG ATGAACAGGC CAACCAGGAA AATGATGCAC TTCATAAGAA ACAGTTGCTT 
AATTTGTGGA TTTCTGATAC AATGTCTTCT ACTGAGCCAC CATCAAAGCA TGCTGTTACT 
ACTTCCAAAA TGGATATAAT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GTPBP10 ( NM_001042717.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036182.1 Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12695
Clone ID Related Accession (Same CDS sequence)	NM_001042717.2 , NM_001042717.3
Accession Version	NM_001042717.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-14
Organism	Homo sapiens(human)
Product	GTP-binding protein 10 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF351613.1, AK095561.1, AK294325.1, AK125553.1, AC006153.2 and T65158.1. On Dec 9, 2010 this sequence version replaced NM_001042717.1. Transcript Variant: This variant (1) lacks alternate in-frame exons in the 5' coding region, compared to variant 2. The resulting protein (isoform 1) is shorter when it is compared to isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.16990.1, BC144162.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCATT GCAGTTGCGT GTTGTTCAGA AAGTATGGAA ATTTCATCGA TAAGCTAAGA 
CTCTTCACCA GGGGAGGATC CGGTGGAATG GGTTATCCTC GTTTAGGTGG AGAAGGTGGA 
AAAGGTGGTG ATGTCTGGGT TGTAGCCCAG AACAGAATGA CTTTAAAACA ACTTAAAGAC 
AGGTATCCTC GGAAACGGTT TGTGGCTGGA GTAGGAGCAA ACAGCAAATT CCCAAATGCT 
GGAAAATCCT CTTTGCTAAG TTGTGTTTCT CATGCAAAAC CTGCAATTGC AGATTACGCA 
TTTACAACAT TAAAGCCTGA ACTTGGAAAG ATAATGTACA GTGATTTCAA ACAGATATCA 
GTAGCTGATC TTCCGGGTTT AATAGAAGGA GCACATATGA ACAAAGGAAT GGGCCACAAA 
TTCCTCAAGC ATATAGAAAG AACTAGACAA CTACTTTTTG TTGTTGATAT TTCTGGATTT 
CAGCTTTCTT CTCACACTCA ATACAGGACA GCTTTTGAAA CCATAATACT GCTTACAAAA 
GAGTTGGAAT TGTACAAAGA GGAACTTCAG ACAAAACCTG CACTCTTGGC AGTTAATAAA 
ATGGACTTGC CAGATGCCCA AGATAAGTTC CATGAATTGA TGAGCCAGCT CCAGAATCCT 
AAAGATTTTC TGCATTTATT TGAAAAAAAC ATGATTCCAG AGAGGACTGT AGAGTTCCAA 
CATATCATCC CCATATCTGC AGTTACTGGA GAAGGAATCG AAGAATTAAA GAATTGTATA 
AGAAAGTCAC TGGATGAACA GGCCAACCAG GAAAATGATG CACTTCATAA GAAACAGTTG 
CTTAATTTGT GGATTTCTGA TACAATGTCT TCTACTGAGC CACCATCAAA GCATGCTGTT 
ACTACTTCCA AAATGGATAT AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036182.1
CDS	78..1004
Translation	MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII

Target ORF information:

RefSeq Version	NM_001042717.2
Organism	Homo sapiens(human)
Definition	Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042717.2

ORF Insert Sequence:

ATGGTGCATT GCAGTTGCGT GTTGTTCAGA AAGTATGGAA ATTTCATCGA TAAGCTAAGA 
CTCTTCACCA GGGGAGGATC CGGTGGAATG GGTTATCCTC GTTTAGGTGG AGAAGGTGGA 
AAAGGTGGTG ATGTCTGGGT TGTAGCCCAG AACAGAATGA CTTTAAAACA ACTTAAAGAC 
AGGTATCCTC GGAAACGGTT TGTGGCTGGA GTAGGAGCAA ACAGCAAATT CCCAAATGCT 
GGAAAATCCT CTTTGCTAAG TTGTGTTTCT CATGCAAAAC CTGCAATTGC AGATTACGCA 
TTTACAACAT TAAAGCCTGA ACTTGGAAAG ATAATGTACA GTGATTTCAA ACAGATATCA 
GTAGCTGATC TTCCGGGTTT AATAGAAGGA GCACATATGA ACAAAGGAAT GGGCCACAAA 
TTCCTCAAGC ATATAGAAAG AACTAGACAA CTACTTTTTG TTGTTGATAT TTCTGGATTT 
CAGCTTTCTT CTCACACTCA ATACAGGACA GCTTTTGAAA CCATAATACT GCTTACAAAA 
GAGTTGGAAT TGTACAAAGA GGAACTTCAG ACAAAACCTG CACTCTTGGC AGTTAATAAA 
ATGGACTTGC CAGATGCCCA AGATAAGTTC CATGAATTGA TGAGCCAGCT CCAGAATCCT 
AAAGATTTTC TGCATTTATT TGAAAAAAAC ATGATTCCAG AGAGGACTGT AGAGTTCCAA 
CATATCATCC CCATATCTGC AGTTACTGGA GAAGGAATCG AAGAATTAAA GAATTGTATA 
AGAAAGTCAC TGGATGAACA GGCCAACCAG GAAAATGATG CACTTCATAA GAAACAGTTG 
CTTAATTTGT GGATTTCTGA TACAATGTCT TCTACTGAGC CACCATCAAA GCATGCTGTT 
ACTACTTCCA AAATGGATAT AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GTPBP10 ( NM_001042717.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001036182.1 Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 1, mRNA.

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CloneID	OHu12695
Clone ID Related Accession (Same CDS sequence)	NM_001042717.2 , NM_001042717.3
Accession Version	NM_001042717.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-20
Organism	Homo sapiens(human)
Product	GTP-binding protein 10 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK095561.1, AK294325.1, AK125553.1, AC006153.2 and T65158.1. On Jun 2, 2019 this sequence version replaced NM_001042717.2. Transcript Variant: This variant (1) lacks alternate in-frame exons in the 5' coding region, compared to variant 2. The resulting protein (isoform 1) is shorter when it is compared to isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC144162.1, AK294325.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCATT GCAGTTGCGT GTTGTTCAGA AAGTATGGAA ATTTCATCGA TAAGCTAAGA 
CTCTTCACCA GGGGAGGATC CGGTGGAATG GGTTATCCTC GTTTAGGTGG AGAAGGTGGA 
AAAGGTGGTG ATGTCTGGGT TGTAGCCCAG AACAGAATGA CTTTAAAACA ACTTAAAGAC 
AGGTATCCTC GGAAACGGTT TGTGGCTGGA GTAGGAGCAA ACAGCAAATT CCCAAATGCT 
GGAAAATCCT CTTTGCTAAG TTGTGTTTCT CATGCAAAAC CTGCAATTGC AGATTACGCA 
TTTACAACAT TAAAGCCTGA ACTTGGAAAG ATAATGTACA GTGATTTCAA ACAGATATCA 
GTAGCTGATC TTCCGGGTTT AATAGAAGGA GCACATATGA ACAAAGGAAT GGGCCACAAA 
TTCCTCAAGC ATATAGAAAG AACTAGACAA CTACTTTTTG TTGTTGATAT TTCTGGATTT 
CAGCTTTCTT CTCACACTCA ATACAGGACA GCTTTTGAAA CCATAATACT GCTTACAAAA 
GAGTTGGAAT TGTACAAAGA GGAACTTCAG ACAAAACCTG CACTCTTGGC AGTTAATAAA 
ATGGACTTGC CAGATGCCCA AGATAAGTTC CATGAATTGA TGAGCCAGCT CCAGAATCCT 
AAAGATTTTC TGCATTTATT TGAAAAAAAC ATGATTCCAG AGAGGACTGT AGAGTTCCAA 
CATATCATCC CCATATCTGC AGTTACTGGA GAAGGAATCG AAGAATTAAA GAATTGTATA 
AGAAAGTCAC TGGATGAACA GGCCAACCAG GAAAATGATG CACTTCATAA GAAACAGTTG 
CTTAATTTGT GGATTTCTGA TACAATGTCT TCTACTGAGC CACCATCAAA GCATGCTGTT 
ACTACTTCCA AAATGGATAT AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001036182.1
CDS	27..953
Translation	MVHCSCVLFRKYGNFIDKLRLFTRGGSGGMGYPRLGGEGGKGGDVWVVAQNRMTLKQLKDRYPRKRFVAGVGANSKFPNAGKSSLLSCVSHAKPAIADYAFTTLKPELGKIMYSDFKQISVADLPGLIEGAHMNKGMGHKFLKHIERTRQLLFVVDISGFQLSSHTQYRTAFETIILLTKELELYKEELQTKPALLAVNKMDLPDAQDKFHELMSQLQNPKDFLHLFEKNMIPERTVEFQHIIPISAVTGEGIEELKNCIRKSLDEQANQENDALHKKQLLNLWISDTMSSTEPPSKHAVTTSKMDII

Target ORF information:

RefSeq Version	NM_001042717.3
Organism	Homo sapiens(human)
Definition	Homo sapiens GTP binding protein 10 (GTPBP10), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001042717.3

ORF Insert Sequence:

ATGGTGCATT GCAGTTGCGT GTTGTTCAGA AAGTATGGAA ATTTCATCGA TAAGCTAAGA 
CTCTTCACCA GGGGAGGATC CGGTGGAATG GGTTATCCTC GTTTAGGTGG AGAAGGTGGA 
AAAGGTGGTG ATGTCTGGGT TGTAGCCCAG AACAGAATGA CTTTAAAACA ACTTAAAGAC 
AGGTATCCTC GGAAACGGTT TGTGGCTGGA GTAGGAGCAA ACAGCAAATT CCCAAATGCT 
GGAAAATCCT CTTTGCTAAG TTGTGTTTCT CATGCAAAAC CTGCAATTGC AGATTACGCA 
TTTACAACAT TAAAGCCTGA ACTTGGAAAG ATAATGTACA GTGATTTCAA ACAGATATCA 
GTAGCTGATC TTCCGGGTTT AATAGAAGGA GCACATATGA ACAAAGGAAT GGGCCACAAA 
TTCCTCAAGC ATATAGAAAG AACTAGACAA CTACTTTTTG TTGTTGATAT TTCTGGATTT 
CAGCTTTCTT CTCACACTCA ATACAGGACA GCTTTTGAAA CCATAATACT GCTTACAAAA 
GAGTTGGAAT TGTACAAAGA GGAACTTCAG ACAAAACCTG CACTCTTGGC AGTTAATAAA 
ATGGACTTGC CAGATGCCCA AGATAAGTTC CATGAATTGA TGAGCCAGCT CCAGAATCCT 
AAAGATTTTC TGCATTTATT TGAAAAAAAC ATGATTCCAG AGAGGACTGT AGAGTTCCAA 
CATATCATCC CCATATCTGC AGTTACTGGA GAAGGAATCG AAGAATTAAA GAATTGTATA 
AGAAAGTCAC TGGATGAACA GGCCAACCAG GAAAATGATG CACTTCATAA GAAACAGTTG 
CTTAATTTGT GGATTTCTGA TACAATGTCT TCTACTGAGC CACCATCAAA GCATGCTGTT 
ACTACTTCCA AAATGGATAT AATTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.
The American journal of clinical nutrition98(3)668-76(2013 Sep)
van Meurs JB,Pare G,Schwartz SM,Hazra A,Tanaka T,Vermeulen SH,Cotlarciuc I,Yuan X,M?larstig A,Bandinelli S,Bis JC,Blom H,Brown MJ,Chen C,Chen YD,Clarke RJ,Dehghan A,Erdmann J,Ferrucci L,Hamsten A,Hofman A,Hunter DJ,Goel A,Johnson AD,Kathiresan S,Kampman E,Kiel DP,Kiemeney LA,Chambers JC,Kraft P,Lindemans J,McKnight B,Nelson CP,O'Donnell CJ,Psaty BM,Ridker PM,Rivadeneira F,Rose LM,Seedorf U,Siscovick DS,Schunkert H,Selhub J,Ueland PM,Vollenweider P,Waeber G,Waterworth DM,Watkins H,Witteman JC,den Heijer M,Jacques P,Uitterlinden AG,Kooner JS,Rader DJ,Reilly MP,Mooser V,Chasman DI,Samani NJ,Ahmadi KR

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.
Genome research17(6)746-59(2007 Jun)
Denoeud F,Kapranov P,Ucla C,Frankish A,Castelo R,Drenkow J,Lagarde J,Alioto T,Manzano C,Chrast J,Dike S,Wyss C,Henrichsen CN,Holroyd N,Dickson MC,Taylor R,Hance Z,Foissac S,Myers RM,Rogers J,Hubbard T,Harrow J,Guig? R,Gingeras TR,Antonarakis SE,Reymond A

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GTPBP10 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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