STK40 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	STK40
Entrez Gene ID	83931
Full Name	serine/threonine kinase 40
Synonyms	SHIK,SgK495
General protein information	Preferred Names serine/threonine kinase 40 Names serine/threonine-protein kinase 40 SINK-homologous serine/threonine-protein kinase Ser/Thr-like kinase sugen kinase 495
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p34.3
Disorder MIM:	609437

mRNA and Protein(s)

mRNA	Protein	Name
NM_001282547.2	NP_001269476.1	serine/threonine-protein kinase 40 isoform 2
NM_001282546.1	NP_001269475.1	serine/threonine-protein kinase 40 isoform 1
NM_001282547.1	NP_001269476.1	serine/threonine-protein kinase 40 isoform 2
NM_032017.2	NP_114406.1	serine/threonine-protein kinase 40 isoform 2
NM_032017.3	NP_114406.1	serine/threonine-protein kinase 40 isoform 2
NM_001282546.2	NP_001269475.1	serine/threonine-protein kinase 40 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	STK40	NP_001269475.1
Pan troglodytes (chimpanzee)	STK40	XP_003308050.1
Rattus norvegicus (Norway rat)	Stk40	NP_898879.2
Gallus gallus (chicken)	STK40	NP_989797.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008948	XP_319703.4
	STK40	XP_002802356.1
Canis lupus familiaris (dog)	STK40	XP_539592.4
Mus musculus (house mouse)	Stk40	NP_001139299.1
Danio rerio (zebrafish)	stk40	XP_693275.5
Bos taurus (cattle)	STK40	NP_001069195.1
Xenopus tropicalis (tropical clawed frog)	stk40	NP_001120455.1

Gene Ontology
Bibliography

Related articles in PubMed

The major miR-31 target genes STK40 and LATS2 and their implications in the regulation of keratinocyte growth and hair differentiation.
Luan L, Shi J, Yu Z, Andl T
Experimental dermatology26(6)497-504(2017 Jun)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

microRNA-130a Promotes Human Keratinocyte Viability and Migration and Inhibits Apoptosis Through Direct Regulation of STK40-Mediated NF-?B Pathway and Indirect Regulation of SOX9-Meditated JNK/MAPK Pathway: A Potential Role in Psoriasis.
Xiong Y, Chen H, Liu L, Lu L, Wang Z, Tian F, Zhao Y
DNA and cell biology36(3)219-226(2017 Mar)

STK40 Is a Pseudokinase that Binds the E3?Ubiquitin Ligase COP1.
Durzynska I, Xu X, Adelmant G, Ficarro SB, Marto JA, Sliz P, Uljon S, Blacklow SC
Structure (London, England : 1993)25(2)287-294(2017 Feb)

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
So J, Pasculescu A, Dai AY, Williton K, James A, Nguyen V, Creixell P, Schoof EM, Sinclair J, Barrios-Rodiles M, Gu J, Krizus A, Williams R, Olhovsky M, Dennis JW, Wrana JL, Linding R, Jorgensen C, Pawson T, Colwill K
Science signaling8(371)rs3(2015 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that STK40 was a direct target of microRNA miR-130a, and overexpressing miR-130a significantly upregulated NF-kappaB p65, SOX9, JNK and p38MAPK proteins.
Title: microRNA-130a Promotes Human Keratinocyte Viability and Migration and Inhibits Apoptosis Through Direct Regulation of STK40-Mediated NF-?B Pathway and Indirect Regulation of SOX9-Meditated JNK/MAPK Pathway: A Potential Role in Psoriasis.

STK40 binds the COP1 WD40 domain using a VPD/E motif in its C-terminal tail.
Title: STK40 Is a Pseudokinase that Binds the E3?Ubiquitin Ligase COP1.

identification as a negative regulator of NF-kappaB- and p53-mediated gene transcription [SINK-homologous serine-threonine kinase]
Title: Identification of a novel serine/threonine kinase that inhibits TNF-induced NF-kappaB activation and p53-induced transcription.

The following STK40 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STK40 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04753	NM_001282547.2 Latest version!	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu04753	NM_032017.3 Latest version!	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu05010	NM_001282546.2 Latest version!	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
View Old Accession Versions >>
OHu04753	NM_001282547.1	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu04753	NM_032017.2	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu05010	NM_001282546.1	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STK40 ( NM_001282547.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269476.1 Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04753
Clone ID Related Accession (Same CDS sequence)	NM_001282547.2 , NM_001282547.1 , NM_032017.2 , NM_032017.3
Accession Version	NM_001282547.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase 40 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA375448.1 and BC007835.2. On Jun 2, 2019 this sequence version replaced NM_001282547.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Both variants 2 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: BC007835.2, SRR1660809.222147.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820689 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGGTCCCCGT 
CTGGGCAACT CACCGGTGCC AAGCATAGTG CAGTGTTTGG CGAGGAAAGA TGGCACGGAT 
GACTTCTATC AGCTGAAGAT CCTGACCCTG GAGGAGAGGG GGGACCAAGG CATAGAGAGC 
CAGGAAGAGC GGCAGGGCAA GATGCTGCTG CACACCGAGT ACTCACTGCT GTCTCTCCTG 
CACACGCAGG ATGGCGTGGT GCACCACCAC GGCCTCTTCC AGGACCGCAC CTGTGAAATC 
GTTGAGGACA CAGAATCCAG CCGGATGGTT AAGAAGATGA AGAAGCGCAT CTGCCTCGTC 
CTGGACTGCC TCTGTGCTCA TGACTTCAGC GATAAGACCG CTGACCTCAT CAACCTGCAG 
CACTACGTCA TCAAGGAGAA GAGGCTCAGC GAGAGGGAGA CTGTGGTAAT CTTCTACGAC 
GTGGTCCGCG TGGTGGAGGC CCTGCACCAG AAAAATATCG TGCACAGAGA CCTGAAGCTG 
GGGAACATGG TGCTCAACAA GAGGACACAT CGGATAACCA TCACCAACTT CTGCCTCGGG 
AAGCATCTGG TGAGCGAGGG GGACCTGCTG AAGGACCAGA GAGGGAGCCC TGCCTACATC 
AGTCCCGACG TGCTCAGCGG CCGGCCGTAC CGTGGCAAGC CCAGTGACAT GTGGGCCCTG 
GGCGTGGTGC TCTTCACCAT GCTGTATGGC CAGTTCCCCT TCTACGACAG CATCCCGCAG 
GAGCTCTTCC GCAAGATCAA GGCTGCCGAG TATACCATTC CTGAGGATGG ACGGGTTTCT 
GAGAACACCG TGTGTCTCAT CCGGAAGCTG CTGGTCCTTG ACCCCCAGCA GCGCCTGGCC 
GCCGCCGACG TCCTGGAGGC CCTCAGTGCC ATCATTGCAT CATGGCAGTC CCTGTCATCT 
CTGAGTGGGC CTTTGCAAGT GGTTCCTGAC ATTGATGACC AAATGAGCAA TGCGGATAGC 
TCCCAGGAGG CGAAGGTGAC GGAGGAGTGC TCCCAGTACG AGTTTGAGAA CTACATGCGT 
CAGCAGCTGC TGCTGGCCGA GGAGAAGAGC TCCATCCATG ACGCCCGGAG CTGGGTACCC 
AAGCGGCAGT TCGGCAGCGC ACCACCGGTG CGACGGCTGG GCCACGACGC ACAGCCCATG 
ACCTCCTTGG ACACGGCCAT CCTGGCGCAG CGCTACCTGC GGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269476.1
CDS	211..1518
Translation	MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK

Target ORF information:

RefSeq Version	NM_001282547.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282547.2

ORF Insert Sequence:

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGGTCCCCGT 
CTGGGCAACT CACCGGTGCC AAGCATAGTG CAGTGTTTGG CGAGGAAAGA TGGCACGGAT 
GACTTCTATC AGCTGAAGAT CCTGACCCTG GAGGAGAGGG GGGACCAAGG CATAGAGAGC 
CAGGAAGAGC GGCAGGGCAA GATGCTGCTG CACACCGAGT ACTCACTGCT GTCTCTCCTG 
CACACGCAGG ATGGCGTGGT GCACCACCAC GGCCTCTTCC AGGACCGCAC CTGTGAAATC 
GTTGAGGACA CAGAATCCAG CCGGATGGTT AAGAAGATGA AGAAGCGCAT CTGCCTCGTC 
CTGGACTGCC TCTGTGCTCA TGACTTCAGC GATAAGACCG CTGACCTCAT CAACCTGCAG 
CACTACGTCA TCAAGGAGAA GAGGCTCAGC GAGAGGGAGA CTGTGGTAAT CTTCTACGAC 
GTGGTCCGCG TGGTGGAGGC CCTGCACCAG AAAAATATCG TGCACAGAGA CCTGAAGCTG 
GGGAACATGG TGCTCAACAA GAGGACACAT CGGATAACCA TCACCAACTT CTGCCTCGGG 
AAGCATCTGG TGAGCGAGGG GGACCTGCTG AAGGACCAGA GAGGGAGCCC TGCCTACATC 
AGTCCCGACG TGCTCAGCGG CCGGCCGTAC CGTGGCAAGC CCAGTGACAT GTGGGCCCTG 
GGCGTGGTGC TCTTCACCAT GCTGTATGGC CAGTTCCCCT TCTACGACAG CATCCCGCAG 
GAGCTCTTCC GCAAGATCAA GGCTGCCGAG TATACCATTC CTGAGGATGG ACGGGTTTCT 
GAGAACACCG TGTGTCTCAT CCGGAAGCTG CTGGTCCTTG ACCCCCAGCA GCGCCTGGCC 
GCCGCCGACG TCCTGGAGGC CCTCAGTGCC ATCATTGCAT CATGGCAGTC CCTGTCATCT 
CTGAGTGGGC CTTTGCAAGT GGTTCCTGAC ATTGATGACC AAATGAGCAA TGCGGATAGC 
TCCCAGGAGG CGAAGGTGAC GGAGGAGTGC TCCCAGTACG AGTTTGAGAA CTACATGCGT 
CAGCAGCTGC TGCTGGCCGA GGAGAAGAGC TCCATCCATG ACGCCCGGAG CTGGGTACCC 
AAGCGGCAGT TCGGCAGCGC ACCACCGGTG CGACGGCTGG GCCACGACGC ACAGCCCATG 
ACCTCCTTGG ACACGGCCAT CCTGGCGCAG CGCTACCTGC GGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STK40 ( NM_001282547.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269476.1 Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04753
Clone ID Related Accession (Same CDS sequence)	NM_001282547.2 , NM_001282547.1 , NM_032017.2 , NM_032017.3
Accession Version	NM_001282547.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase 40 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA375448.1, BC007835.2 and AW269508.1. On Sep 13, 2013 this sequence version replaced XM_005271249.1. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Both variants 2 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.158700.1, SRR1803616.73855.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820689 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGGTCCCCGT 
CTGGGCAACT CACCGGTGCC AAGCATAGTG CAGTGTTTGG CGAGGAAAGA TGGCACGGAT 
GACTTCTATC AGCTGAAGAT CCTGACCCTG GAGGAGAGGG GGGACCAAGG CATAGAGAGC 
CAGGAAGAGC GGCAGGGCAA GATGCTGCTG CACACCGAGT ACTCACTGCT GTCTCTCCTG 
CACACGCAGG ATGGCGTGGT GCACCACCAC GGCCTCTTCC AGGACCGCAC CTGTGAAATC 
GTTGAGGACA CAGAATCCAG CCGGATGGTT AAGAAGATGA AGAAGCGCAT CTGCCTCGTC 
CTGGACTGCC TCTGTGCTCA TGACTTCAGC GATAAGACCG CTGACCTCAT CAACCTGCAG 
CACTACGTCA TCAAGGAGAA GAGGCTCAGC GAGAGGGAGA CTGTGGTAAT CTTCTACGAC 
GTGGTCCGCG TGGTGGAGGC CCTGCACCAG AAAAATATCG TGCACAGAGA CCTGAAGCTG 
GGGAACATGG TGCTCAACAA GAGGACACAT CGGATAACCA TCACCAACTT CTGCCTCGGG 
AAGCATCTGG TGAGCGAGGG GGACCTGCTG AAGGACCAGA GAGGGAGCCC TGCCTACATC 
AGTCCCGACG TGCTCAGCGG CCGGCCGTAC CGTGGCAAGC CCAGTGACAT GTGGGCCCTG 
GGCGTGGTGC TCTTCACCAT GCTGTATGGC CAGTTCCCCT TCTACGACAG CATCCCGCAG 
GAGCTCTTCC GCAAGATCAA GGCTGCCGAG TATACCATTC CTGAGGATGG ACGGGTTTCT 
GAGAACACCG TGTGTCTCAT CCGGAAGCTG CTGGTCCTTG ACCCCCAGCA GCGCCTGGCC 
GCCGCCGACG TCCTGGAGGC CCTCAGTGCC ATCATTGCAT CATGGCAGTC CCTGTCATCT 
CTGAGTGGGC CTTTGCAAGT GGTTCCTGAC ATTGATGACC AAATGAGCAA TGCGGATAGC 
TCCCAGGAGG CGAAGGTGAC GGAGGAGTGC TCCCAGTACG AGTTTGAGAA CTACATGCGT 
CAGCAGCTGC TGCTGGCCGA GGAGAAGAGC TCCATCCATG ACGCCCGGAG CTGGGTACCC 
AAGCGGCAGT TCGGCAGCGC ACCACCGGTG CGACGGCTGG GCCACGACGC ACAGCCCATG 
ACCTCCTTGG ACACGGCCAT CCTGGCGCAG CGCTACCTGC GGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269476.1
CDS	214..1521
Translation	MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK

Target ORF information:

RefSeq Version	NM_001282547.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282547.1

ORF Insert Sequence:

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGGTCCCCGT 
CTGGGCAACT CACCGGTGCC AAGCATAGTG CAGTGTTTGG CGAGGAAAGA TGGCACGGAT 
GACTTCTATC AGCTGAAGAT CCTGACCCTG GAGGAGAGGG GGGACCAAGG CATAGAGAGC 
CAGGAAGAGC GGCAGGGCAA GATGCTGCTG CACACCGAGT ACTCACTGCT GTCTCTCCTG 
CACACGCAGG ATGGCGTGGT GCACCACCAC GGCCTCTTCC AGGACCGCAC CTGTGAAATC 
GTTGAGGACA CAGAATCCAG CCGGATGGTT AAGAAGATGA AGAAGCGCAT CTGCCTCGTC 
CTGGACTGCC TCTGTGCTCA TGACTTCAGC GATAAGACCG CTGACCTCAT CAACCTGCAG 
CACTACGTCA TCAAGGAGAA GAGGCTCAGC GAGAGGGAGA CTGTGGTAAT CTTCTACGAC 
GTGGTCCGCG TGGTGGAGGC CCTGCACCAG AAAAATATCG TGCACAGAGA CCTGAAGCTG 
GGGAACATGG TGCTCAACAA GAGGACACAT CGGATAACCA TCACCAACTT CTGCCTCGGG 
AAGCATCTGG TGAGCGAGGG GGACCTGCTG AAGGACCAGA GAGGGAGCCC TGCCTACATC 
AGTCCCGACG TGCTCAGCGG CCGGCCGTAC CGTGGCAAGC CCAGTGACAT GTGGGCCCTG 
GGCGTGGTGC TCTTCACCAT GCTGTATGGC CAGTTCCCCT TCTACGACAG CATCCCGCAG 
GAGCTCTTCC GCAAGATCAA GGCTGCCGAG TATACCATTC CTGAGGATGG ACGGGTTTCT 
GAGAACACCG TGTGTCTCAT CCGGAAGCTG CTGGTCCTTG ACCCCCAGCA GCGCCTGGCC 
GCCGCCGACG TCCTGGAGGC CCTCAGTGCC ATCATTGCAT CATGGCAGTC CCTGTCATCT 
CTGAGTGGGC CTTTGCAAGT GGTTCCTGAC ATTGATGACC AAATGAGCAA TGCGGATAGC 
TCCCAGGAGG CGAAGGTGAC GGAGGAGTGC TCCCAGTACG AGTTTGAGAA CTACATGCGT 
CAGCAGCTGC TGCTGGCCGA GGAGAAGAGC TCCATCCATG ACGCCCGGAG CTGGGTACCC 
AAGCGGCAGT TCGGCAGCGC ACCACCGGTG CGACGGCTGG GCCACGACGC ACAGCCCATG 
ACCTCCTTGG ACACGGCCAT CCTGGCGCAG CGCTACCTGC GGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STK40 ( NM_032017.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_114406.1 Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu04753
Clone ID Related Accession (Same CDS sequence)	NM_001282547.2 , NM_001282547.1 , NM_032017.2 , NM_032017.3
Accession Version	NM_032017.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase 40 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA375448.1, AL834137.1 and AW269508.1. On Sep 13, 2013 this sequence version replaced NM_032017.1. Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Both variants 2 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: AL834137.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGGTCCCCGT 
CTGGGCAACT CACCGGTGCC AAGCATAGTG CAGTGTTTGG CGAGGAAAGA TGGCACGGAT 
GACTTCTATC AGCTGAAGAT CCTGACCCTG GAGGAGAGGG GGGACCAAGG CATAGAGAGC 
CAGGAAGAGC GGCAGGGCAA GATGCTGCTG CACACCGAGT ACTCACTGCT GTCTCTCCTG 
CACACGCAGG ATGGCGTGGT GCACCACCAC GGCCTCTTCC AGGACCGCAC CTGTGAAATC 
GTTGAGGACA CAGAATCCAG CCGGATGGTT AAGAAGATGA AGAAGCGCAT CTGCCTCGTC 
CTGGACTGCC TCTGTGCTCA TGACTTCAGC GATAAGACCG CTGACCTCAT CAACCTGCAG 
CACTACGTCA TCAAGGAGAA GAGGCTCAGC GAGAGGGAGA CTGTGGTAAT CTTCTACGAC 
GTGGTCCGCG TGGTGGAGGC CCTGCACCAG AAAAATATCG TGCACAGAGA CCTGAAGCTG 
GGGAACATGG TGCTCAACAA GAGGACACAT CGGATAACCA TCACCAACTT CTGCCTCGGG 
AAGCATCTGG TGAGCGAGGG GGACCTGCTG AAGGACCAGA GAGGGAGCCC TGCCTACATC 
AGTCCCGACG TGCTCAGCGG CCGGCCGTAC CGTGGCAAGC CCAGTGACAT GTGGGCCCTG 
GGCGTGGTGC TCTTCACCAT GCTGTATGGC CAGTTCCCCT TCTACGACAG CATCCCGCAG 
GAGCTCTTCC GCAAGATCAA GGCTGCCGAG TATACCATTC CTGAGGATGG ACGGGTTTCT 
GAGAACACCG TGTGTCTCAT CCGGAAGCTG CTGGTCCTTG ACCCCCAGCA GCGCCTGGCC 
GCCGCCGACG TCCTGGAGGC CCTCAGTGCC ATCATTGCAT CATGGCAGTC CCTGTCATCT 
CTGAGTGGGC CTTTGCAAGT GGTTCCTGAC ATTGATGACC AAATGAGCAA TGCGGATAGC 
TCCCAGGAGG CGAAGGTGAC GGAGGAGTGC TCCCAGTACG AGTTTGAGAA CTACATGCGT 
CAGCAGCTGC TGCTGGCCGA GGAGAAGAGC TCCATCCATG ACGCCCGGAG CTGGGTACCC 
AAGCGGCAGT TCGGCAGCGC ACCACCGGTG CGACGGCTGG GCCACGACGC ACAGCCCATG 
ACCTCCTTGG ACACGGCCAT CCTGGCGCAG CGCTACCTGC GGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114406.1
CDS	451..1758
Translation	MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK

Target ORF information:

RefSeq Version	NM_032017.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032017.2

ORF Insert Sequence:

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGGTCCCCGT 
CTGGGCAACT CACCGGTGCC AAGCATAGTG CAGTGTTTGG CGAGGAAAGA TGGCACGGAT 
GACTTCTATC AGCTGAAGAT CCTGACCCTG GAGGAGAGGG GGGACCAAGG CATAGAGAGC 
CAGGAAGAGC GGCAGGGCAA GATGCTGCTG CACACCGAGT ACTCACTGCT GTCTCTCCTG 
CACACGCAGG ATGGCGTGGT GCACCACCAC GGCCTCTTCC AGGACCGCAC CTGTGAAATC 
GTTGAGGACA CAGAATCCAG CCGGATGGTT AAGAAGATGA AGAAGCGCAT CTGCCTCGTC 
CTGGACTGCC TCTGTGCTCA TGACTTCAGC GATAAGACCG CTGACCTCAT CAACCTGCAG 
CACTACGTCA TCAAGGAGAA GAGGCTCAGC GAGAGGGAGA CTGTGGTAAT CTTCTACGAC 
GTGGTCCGCG TGGTGGAGGC CCTGCACCAG AAAAATATCG TGCACAGAGA CCTGAAGCTG 
GGGAACATGG TGCTCAACAA GAGGACACAT CGGATAACCA TCACCAACTT CTGCCTCGGG 
AAGCATCTGG TGAGCGAGGG GGACCTGCTG AAGGACCAGA GAGGGAGCCC TGCCTACATC 
AGTCCCGACG TGCTCAGCGG CCGGCCGTAC CGTGGCAAGC CCAGTGACAT GTGGGCCCTG 
GGCGTGGTGC TCTTCACCAT GCTGTATGGC CAGTTCCCCT TCTACGACAG CATCCCGCAG 
GAGCTCTTCC GCAAGATCAA GGCTGCCGAG TATACCATTC CTGAGGATGG ACGGGTTTCT 
GAGAACACCG TGTGTCTCAT CCGGAAGCTG CTGGTCCTTG ACCCCCAGCA GCGCCTGGCC 
GCCGCCGACG TCCTGGAGGC CCTCAGTGCC ATCATTGCAT CATGGCAGTC CCTGTCATCT 
CTGAGTGGGC CTTTGCAAGT GGTTCCTGAC ATTGATGACC AAATGAGCAA TGCGGATAGC 
TCCCAGGAGG CGAAGGTGAC GGAGGAGTGC TCCCAGTACG AGTTTGAGAA CTACATGCGT 
CAGCAGCTGC TGCTGGCCGA GGAGAAGAGC TCCATCCATG ACGCCCGGAG CTGGGTACCC 
AAGCGGCAGT TCGGCAGCGC ACCACCGGTG CGACGGCTGG GCCACGACGC ACAGCCCATG 
ACCTCCTTGG ACACGGCCAT CCTGGCGCAG CGCTACCTGC GGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STK40 ( NM_032017.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_114406.1 Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 3, mRNA.

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CloneID	OHu04753
Clone ID Related Accession (Same CDS sequence)	NM_001282547.2 , NM_001282547.1 , NM_032017.2 , NM_032017.3
Accession Version	NM_032017.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1308bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase 40 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA375448.1 and AL834137.1. On Jun 2, 2019 this sequence version replaced NM_032017.2. Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Both variants 2 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: AL834137.1, DRR138518.17048.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGGTCCCCGT 
CTGGGCAACT CACCGGTGCC AAGCATAGTG CAGTGTTTGG CGAGGAAAGA TGGCACGGAT 
GACTTCTATC AGCTGAAGAT CCTGACCCTG GAGGAGAGGG GGGACCAAGG CATAGAGAGC 
CAGGAAGAGC GGCAGGGCAA GATGCTGCTG CACACCGAGT ACTCACTGCT GTCTCTCCTG 
CACACGCAGG ATGGCGTGGT GCACCACCAC GGCCTCTTCC AGGACCGCAC CTGTGAAATC 
GTTGAGGACA CAGAATCCAG CCGGATGGTT AAGAAGATGA AGAAGCGCAT CTGCCTCGTC 
CTGGACTGCC TCTGTGCTCA TGACTTCAGC GATAAGACCG CTGACCTCAT CAACCTGCAG 
CACTACGTCA TCAAGGAGAA GAGGCTCAGC GAGAGGGAGA CTGTGGTAAT CTTCTACGAC 
GTGGTCCGCG TGGTGGAGGC CCTGCACCAG AAAAATATCG TGCACAGAGA CCTGAAGCTG 
GGGAACATGG TGCTCAACAA GAGGACACAT CGGATAACCA TCACCAACTT CTGCCTCGGG 
AAGCATCTGG TGAGCGAGGG GGACCTGCTG AAGGACCAGA GAGGGAGCCC TGCCTACATC 
AGTCCCGACG TGCTCAGCGG CCGGCCGTAC CGTGGCAAGC CCAGTGACAT GTGGGCCCTG 
GGCGTGGTGC TCTTCACCAT GCTGTATGGC CAGTTCCCCT TCTACGACAG CATCCCGCAG 
GAGCTCTTCC GCAAGATCAA GGCTGCCGAG TATACCATTC CTGAGGATGG ACGGGTTTCT 
GAGAACACCG TGTGTCTCAT CCGGAAGCTG CTGGTCCTTG ACCCCCAGCA GCGCCTGGCC 
GCCGCCGACG TCCTGGAGGC CCTCAGTGCC ATCATTGCAT CATGGCAGTC CCTGTCATCT 
CTGAGTGGGC CTTTGCAAGT GGTTCCTGAC ATTGATGACC AAATGAGCAA TGCGGATAGC 
TCCCAGGAGG CGAAGGTGAC GGAGGAGTGC TCCCAGTACG AGTTTGAGAA CTACATGCGT 
CAGCAGCTGC TGCTGGCCGA GGAGAAGAGC TCCATCCATG ACGCCCGGAG CTGGGTACCC 
AAGCGGCAGT TCGGCAGCGC ACCACCGGTG CGACGGCTGG GCCACGACGC ACAGCCCATG 
ACCTCCTTGG ACACGGCCAT CCTGGCGCAG CGCTACCTGC GGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_114406.1
CDS	448..1755
Translation	MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK

Target ORF information:

RefSeq Version	NM_032017.3
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032017.3

ORF Insert Sequence:

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGGTCCCCGT 
CTGGGCAACT CACCGGTGCC AAGCATAGTG CAGTGTTTGG CGAGGAAAGA TGGCACGGAT 
GACTTCTATC AGCTGAAGAT CCTGACCCTG GAGGAGAGGG GGGACCAAGG CATAGAGAGC 
CAGGAAGAGC GGCAGGGCAA GATGCTGCTG CACACCGAGT ACTCACTGCT GTCTCTCCTG 
CACACGCAGG ATGGCGTGGT GCACCACCAC GGCCTCTTCC AGGACCGCAC CTGTGAAATC 
GTTGAGGACA CAGAATCCAG CCGGATGGTT AAGAAGATGA AGAAGCGCAT CTGCCTCGTC 
CTGGACTGCC TCTGTGCTCA TGACTTCAGC GATAAGACCG CTGACCTCAT CAACCTGCAG 
CACTACGTCA TCAAGGAGAA GAGGCTCAGC GAGAGGGAGA CTGTGGTAAT CTTCTACGAC 
GTGGTCCGCG TGGTGGAGGC CCTGCACCAG AAAAATATCG TGCACAGAGA CCTGAAGCTG 
GGGAACATGG TGCTCAACAA GAGGACACAT CGGATAACCA TCACCAACTT CTGCCTCGGG 
AAGCATCTGG TGAGCGAGGG GGACCTGCTG AAGGACCAGA GAGGGAGCCC TGCCTACATC 
AGTCCCGACG TGCTCAGCGG CCGGCCGTAC CGTGGCAAGC CCAGTGACAT GTGGGCCCTG 
GGCGTGGTGC TCTTCACCAT GCTGTATGGC CAGTTCCCCT TCTACGACAG CATCCCGCAG 
GAGCTCTTCC GCAAGATCAA GGCTGCCGAG TATACCATTC CTGAGGATGG ACGGGTTTCT 
GAGAACACCG TGTGTCTCAT CCGGAAGCTG CTGGTCCTTG ACCCCCAGCA GCGCCTGGCC 
GCCGCCGACG TCCTGGAGGC CCTCAGTGCC ATCATTGCAT CATGGCAGTC CCTGTCATCT 
CTGAGTGGGC CTTTGCAAGT GGTTCCTGAC ATTGATGACC AAATGAGCAA TGCGGATAGC 
TCCCAGGAGG CGAAGGTGAC GGAGGAGTGC TCCCAGTACG AGTTTGAGAA CTACATGCGT 
CAGCAGCTGC TGCTGGCCGA GGAGAAGAGC TCCATCCATG ACGCCCGGAG CTGGGTACCC 
AAGCGGCAGT TCGGCAGCGC ACCACCGGTG CGACGGCTGG GCCACGACGC ACAGCCCATG 
ACCTCCTTGG ACACGGCCAT CCTGGCGCAG CGCTACCTGC GGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STK40 ( NM_001282546.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269475.1 Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 1, mRNA.

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CloneID	OHu05010
Clone ID Related Accession (Same CDS sequence)	NM_001282546.1 , NM_001282546.2
Accession Version	NM_001282546.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1323bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase 40 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA375448.1, BC008344.1, AL834137.1 and AW269508.1. On Sep 13, 2013 this sequence version replaced XM_005271248.1. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC008344.1, SRR1803611.118416.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820689 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGCTCTCTGT 
GCCGTAGGTC CCCGTCTGGG CAACTCACCG GTGCCAAGCA TAGTGCAGTG TTTGGCGAGG 
AAAGATGGCA CGGATGACTT CTATCAGCTG AAGATCCTGA CCCTGGAGGA GAGGGGGGAC 
CAAGGCATAG AGAGCCAGGA AGAGCGGCAG GGCAAGATGC TGCTGCACAC CGAGTACTCA 
CTGCTGTCTC TCCTGCACAC GCAGGATGGC GTGGTGCACC ACCACGGCCT CTTCCAGGAC 
CGCACCTGTG AAATCGTTGA GGACACAGAA TCCAGCCGGA TGGTTAAGAA GATGAAGAAG 
CGCATCTGCC TCGTCCTGGA CTGCCTCTGT GCTCATGACT TCAGCGATAA GACCGCTGAC 
CTCATCAACC TGCAGCACTA CGTCATCAAG GAGAAGAGGC TCAGCGAGAG GGAGACTGTG 
GTAATCTTCT ACGACGTGGT CCGCGTGGTG GAGGCCCTGC ACCAGAAAAA TATCGTGCAC 
AGAGACCTGA AGCTGGGGAA CATGGTGCTC AACAAGAGGA CACATCGGAT AACCATCACC 
AACTTCTGCC TCGGGAAGCA TCTGGTGAGC GAGGGGGACC TGCTGAAGGA CCAGAGAGGG 
AGCCCTGCCT ACATCAGTCC CGACGTGCTC AGCGGCCGGC CGTACCGTGG CAAGCCCAGT 
GACATGTGGG CCCTGGGCGT GGTGCTCTTC ACCATGCTGT ATGGCCAGTT CCCCTTCTAC 
GACAGCATCC CGCAGGAGCT CTTCCGCAAG ATCAAGGCTG CCGAGTATAC CATTCCTGAG 
GATGGACGGG TTTCTGAGAA CACCGTGTGT CTCATCCGGA AGCTGCTGGT CCTTGACCCC 
CAGCAGCGCC TGGCCGCCGC CGACGTCCTG GAGGCCCTCA GTGCCATCAT TGCATCATGG 
CAGTCCCTGT CATCTCTGAG TGGGCCTTTG CAAGTGGTTC CTGACATTGA TGACCAAATG 
AGCAATGCGG ATAGCTCCCA GGAGGCGAAG GTGACGGAGG AGTGCTCCCA GTACGAGTTT 
GAGAACTACA TGCGTCAGCA GCTGCTGCTG GCCGAGGAGA AGAGCTCCAT CCATGACGCC 
CGGAGCTGGG TACCCAAGCG GCAGTTCGGC AGCGCACCAC CGGTGCGACG GCTGGGCCAC 
GACGCACAGC CCATGACCTC CTTGGACACG GCCATCCTGG CGCAGCGCTA CCTGCGGAAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269475.1
CDS	214..1536
Translation	MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILALCAVGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK

Target ORF information:

RefSeq Version	NM_001282546.1
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282546.1

ORF Insert Sequence:

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGCTCTCTGT 
GCCGTAGGTC CCCGTCTGGG CAACTCACCG GTGCCAAGCA TAGTGCAGTG TTTGGCGAGG 
AAAGATGGCA CGGATGACTT CTATCAGCTG AAGATCCTGA CCCTGGAGGA GAGGGGGGAC 
CAAGGCATAG AGAGCCAGGA AGAGCGGCAG GGCAAGATGC TGCTGCACAC CGAGTACTCA 
CTGCTGTCTC TCCTGCACAC GCAGGATGGC GTGGTGCACC ACCACGGCCT CTTCCAGGAC 
CGCACCTGTG AAATCGTTGA GGACACAGAA TCCAGCCGGA TGGTTAAGAA GATGAAGAAG 
CGCATCTGCC TCGTCCTGGA CTGCCTCTGT GCTCATGACT TCAGCGATAA GACCGCTGAC 
CTCATCAACC TGCAGCACTA CGTCATCAAG GAGAAGAGGC TCAGCGAGAG GGAGACTGTG 
GTAATCTTCT ACGACGTGGT CCGCGTGGTG GAGGCCCTGC ACCAGAAAAA TATCGTGCAC 
AGAGACCTGA AGCTGGGGAA CATGGTGCTC AACAAGAGGA CACATCGGAT AACCATCACC 
AACTTCTGCC TCGGGAAGCA TCTGGTGAGC GAGGGGGACC TGCTGAAGGA CCAGAGAGGG 
AGCCCTGCCT ACATCAGTCC CGACGTGCTC AGCGGCCGGC CGTACCGTGG CAAGCCCAGT 
GACATGTGGG CCCTGGGCGT GGTGCTCTTC ACCATGCTGT ATGGCCAGTT CCCCTTCTAC 
GACAGCATCC CGCAGGAGCT CTTCCGCAAG ATCAAGGCTG CCGAGTATAC CATTCCTGAG 
GATGGACGGG TTTCTGAGAA CACCGTGTGT CTCATCCGGA AGCTGCTGGT CCTTGACCCC 
CAGCAGCGCC TGGCCGCCGC CGACGTCCTG GAGGCCCTCA GTGCCATCAT TGCATCATGG 
CAGTCCCTGT CATCTCTGAG TGGGCCTTTG CAAGTGGTTC CTGACATTGA TGACCAAATG 
AGCAATGCGG ATAGCTCCCA GGAGGCGAAG GTGACGGAGG AGTGCTCCCA GTACGAGTTT 
GAGAACTACA TGCGTCAGCA GCTGCTGCTG GCCGAGGAGA AGAGCTCCAT CCATGACGCC 
CGGAGCTGGG TACCCAAGCG GCAGTTCGGC AGCGCACCAC CGGTGCGACG GCTGGGCCAC 
GACGCACAGC CCATGACCTC CTTGGACACG GCCATCCTGG CGCAGCGCTA CCTGCGGAAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STK40 ( NM_001282546.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269475.1 Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu05010
Clone ID Related Accession (Same CDS sequence)	NM_001282546.1 , NM_001282546.2
Accession Version	NM_001282546.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1323bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	serine/threonine-protein kinase 40 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA375448.1, BC008344.1 and AL834137.1. On Jun 2, 2019 this sequence version replaced NM_001282546.1. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC008344.1, SRR1803611.118416.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820689 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGCTCTCTGT 
GCCGTAGGTC CCCGTCTGGG CAACTCACCG GTGCCAAGCA TAGTGCAGTG TTTGGCGAGG 
AAAGATGGCA CGGATGACTT CTATCAGCTG AAGATCCTGA CCCTGGAGGA GAGGGGGGAC 
CAAGGCATAG AGAGCCAGGA AGAGCGGCAG GGCAAGATGC TGCTGCACAC CGAGTACTCA 
CTGCTGTCTC TCCTGCACAC GCAGGATGGC GTGGTGCACC ACCACGGCCT CTTCCAGGAC 
CGCACCTGTG AAATCGTTGA GGACACAGAA TCCAGCCGGA TGGTTAAGAA GATGAAGAAG 
CGCATCTGCC TCGTCCTGGA CTGCCTCTGT GCTCATGACT TCAGCGATAA GACCGCTGAC 
CTCATCAACC TGCAGCACTA CGTCATCAAG GAGAAGAGGC TCAGCGAGAG GGAGACTGTG 
GTAATCTTCT ACGACGTGGT CCGCGTGGTG GAGGCCCTGC ACCAGAAAAA TATCGTGCAC 
AGAGACCTGA AGCTGGGGAA CATGGTGCTC AACAAGAGGA CACATCGGAT AACCATCACC 
AACTTCTGCC TCGGGAAGCA TCTGGTGAGC GAGGGGGACC TGCTGAAGGA CCAGAGAGGG 
AGCCCTGCCT ACATCAGTCC CGACGTGCTC AGCGGCCGGC CGTACCGTGG CAAGCCCAGT 
GACATGTGGG CCCTGGGCGT GGTGCTCTTC ACCATGCTGT ATGGCCAGTT CCCCTTCTAC 
GACAGCATCC CGCAGGAGCT CTTCCGCAAG ATCAAGGCTG CCGAGTATAC CATTCCTGAG 
GATGGACGGG TTTCTGAGAA CACCGTGTGT CTCATCCGGA AGCTGCTGGT CCTTGACCCC 
CAGCAGCGCC TGGCCGCCGC CGACGTCCTG GAGGCCCTCA GTGCCATCAT TGCATCATGG 
CAGTCCCTGT CATCTCTGAG TGGGCCTTTG CAAGTGGTTC CTGACATTGA TGACCAAATG 
AGCAATGCGG ATAGCTCCCA GGAGGCGAAG GTGACGGAGG AGTGCTCCCA GTACGAGTTT 
GAGAACTACA TGCGTCAGCA GCTGCTGCTG GCCGAGGAGA AGAGCTCCAT CCATGACGCC 
CGGAGCTGGG TACCCAAGCG GCAGTTCGGC AGCGCACCAC CGGTGCGACG GCTGGGCCAC 
GACGCACAGC CCATGACCTC CTTGGACACG GCCATCCTGG CGCAGCGCTA CCTGCGGAAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269475.1
CDS	211..1533
Translation	MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILALCAVGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEIVEDTESSRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSAIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSIHDARSWVPKRQFGSAPPVRRLGHDAQPMTSLDTAILAQRYLRK

Target ORF information:

RefSeq Version	NM_001282546.2
Organism	Homo sapiens(human)
Definition	Homo sapiens serine/threonine kinase 40 (STK40), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282546.2

ORF Insert Sequence:

ATGAAGCGGA GAGCATCAGA CAGAGGAGCT GGGGAAACGT CGGCCAGGGC CAAGGCTCTA 
GGAAGTGGGA TTTCTGGAAA TAATGCAAAG AGAGCTGGAC CATTCATCCT TGCTCTCTGT 
GCCGTAGGTC CCCGTCTGGG CAACTCACCG GTGCCAAGCA TAGTGCAGTG TTTGGCGAGG 
AAAGATGGCA CGGATGACTT CTATCAGCTG AAGATCCTGA CCCTGGAGGA GAGGGGGGAC 
CAAGGCATAG AGAGCCAGGA AGAGCGGCAG GGCAAGATGC TGCTGCACAC CGAGTACTCA 
CTGCTGTCTC TCCTGCACAC GCAGGATGGC GTGGTGCACC ACCACGGCCT CTTCCAGGAC 
CGCACCTGTG AAATCGTTGA GGACACAGAA TCCAGCCGGA TGGTTAAGAA GATGAAGAAG 
CGCATCTGCC TCGTCCTGGA CTGCCTCTGT GCTCATGACT TCAGCGATAA GACCGCTGAC 
CTCATCAACC TGCAGCACTA CGTCATCAAG GAGAAGAGGC TCAGCGAGAG GGAGACTGTG 
GTAATCTTCT ACGACGTGGT CCGCGTGGTG GAGGCCCTGC ACCAGAAAAA TATCGTGCAC 
AGAGACCTGA AGCTGGGGAA CATGGTGCTC AACAAGAGGA CACATCGGAT AACCATCACC 
AACTTCTGCC TCGGGAAGCA TCTGGTGAGC GAGGGGGACC TGCTGAAGGA CCAGAGAGGG 
AGCCCTGCCT ACATCAGTCC CGACGTGCTC AGCGGCCGGC CGTACCGTGG CAAGCCCAGT 
GACATGTGGG CCCTGGGCGT GGTGCTCTTC ACCATGCTGT ATGGCCAGTT CCCCTTCTAC 
GACAGCATCC CGCAGGAGCT CTTCCGCAAG ATCAAGGCTG CCGAGTATAC CATTCCTGAG 
GATGGACGGG TTTCTGAGAA CACCGTGTGT CTCATCCGGA AGCTGCTGGT CCTTGACCCC 
CAGCAGCGCC TGGCCGCCGC CGACGTCCTG GAGGCCCTCA GTGCCATCAT TGCATCATGG 
CAGTCCCTGT CATCTCTGAG TGGGCCTTTG CAAGTGGTTC CTGACATTGA TGACCAAATG 
AGCAATGCGG ATAGCTCCCA GGAGGCGAAG GTGACGGAGG AGTGCTCCCA GTACGAGTTT 
GAGAACTACA TGCGTCAGCA GCTGCTGCTG GCCGAGGAGA AGAGCTCCAT CCATGACGCC 
CGGAGCTGGG TACCCAAGCG GCAGTTCGGC AGCGCACCAC CGGTGCGACG GCTGGGCCAC 
GACGCACAGC CCATGACCTC CTTGGACACG GCCATCCTGG CGCAGCGCTA CCTGCGGAAA 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The major miR-31 target genes STK40 and LATS2 and their implications in the regulation of keratinocyte growth and hair differentiation.
Experimental dermatology26(6)497-504(2017 Jun)
Luan L,Shi J,Yu Z,Andl T

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

microRNA-130a Promotes Human Keratinocyte Viability and Migration and Inhibits Apoptosis Through Direct Regulation of STK40-Mediated NF-?B Pathway and Indirect Regulation of SOX9-Meditated JNK/MAPK Pathway: A Potential Role in Psoriasis.
DNA and cell biology36(3)219-226(2017 Mar)
Xiong Y,Chen H,Liu L,Lu L,Wang Z,Tian F,Zhao Y

STK40 Is a Pseudokinase that Binds the E3?Ubiquitin Ligase COP1.
Structure (London, England : 1993)25(2)287-294(2017 Feb)
Durzynska I,Xu X,Adelmant G,Ficarro SB,Marto JA,Sliz P,Uljon S,Blacklow SC

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.
Science signaling8(371)rs3(2015 Apr)
So J,Pasculescu A,Dai AY,Williton K,James A,Nguyen V,Creixell P,Schoof EM,Sinclair J,Barrios-Rodiles M,Gu J,Krizus A,Williams R,Olhovsky M,Dennis JW,Wrana JL,Linding R,Jorgensen C,Pawson T,Colwill K

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STK40 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

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ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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