TUBA4B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TUBA4B
Entrez Gene ID	80086
Full Name	tubulin alpha 4b
Synonyms	TUBA4
General protein information	Preferred Names tubulin alpha 4b Names putative tubulin-like protein alpha-4B tubulin, alpha 4 tubulin, alpha 4b (pseudogene)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q35

mRNA and Protein(s)

mRNA	Protein	Name
NM_001355221.1	NP_001342150.1	putative tubulin-like protein alpha-4B

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Low Expression LncRNA TUBA4B is a Poor Predictor of Prognosis and Regulates Cell Proliferation in Non-Small Cell Lung Cancer.
Chen J, Hu L, Wang J, Zhang F, Chen J, Xu G, Wang Y, Pan Q
Pathology oncology research : POR23(2)265-270(2017 Apr)

Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes.
Villasante A, Wang D, Dobner P, Dolph P, Lewis SA, Cowan NJ
Molecular and cellular biology6(7)2409-19(1986 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Low expression TUBA4B in NSCLC tissue.
Title: Low Expression LncRNA TUBA4B is a Poor Predictor of Prognosis and Regulates Cell Proliferation in Non-Small Cell Lung Cancer.

A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
Title: Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.

The following TUBA4B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TUBA4B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu103419	NM_001355221.1 Latest version!	Homo sapiens tubulin alpha 4b (TUBA4B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TUBA4B ( NM_001355221.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001342150.1 Homo sapiens tubulin alpha 4b (TUBA4B), mRNA.

Price & Availability↑

CloneID	OHu103419
Clone ID Related Accession (Same CDS sequence)	NM_001355221.1
Accession Version	NM_001355221.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 726bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Homo sapiens(human)
Product	putative tubulin-like protein alpha-4B
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC068946.4. On Sep 12, 2017 this sequence version replaced NR_003063.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK024002.1, AU142757.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000490341.3/ ENSP00000487719.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCGGCACC AGCAGACAGA GAGACAAGAC CCCAGCCAGC CCCTGTCCAG GCAGCATGGC 
ACATACCGCC AGATCTTCCA TCCAGAGCAG CTCATCACAG GCAAGGAAGA TGCTGCCAAT 
AACTATGCCT GGGGCCACTA CACCATTGGG AAGGAGTTCA TCGACCTGCT ACTGGACCGG 
ATTCGGAAGC TGGCTGACCA GTGCACAGGA CTTCAGGGCT TCCTGGTGTT CCACAGCCTT 
GGTCGGGGCA CTGGCTCTGA CGTCACCTCA TTCCTGATGG AGTGGCTTTC TGTTAACTAT 
GGCAAGAAAT CCAAGCTGGG ATTCTCCATC TACCCAGCCC CCCAGGTGTC TACAGCCATG 
GTCCAGCCCT ACAACTCTAT CCTGACCACC CACACCACCC TGGAGCACTC AGACTGTGCC 
TTCATGGTGG ACAACAAAGC AATCTATGAC ATCTGCCACT GCAACCTAGA CATCGAGCGC 
CCAACCTACA CCAACCTCAA TCGCCTCATT AGCCAAATTG TCTCCTCCAT CACAGCTTCT 
CTGCGCTTTG ACGGGGCCCT CAATGTGGAC CTGACAGAGT TCCAGACCAA CCTGGTGTCC 
TACCTCACAT CCACTTCCCC CTGGCCACCT ATGCACCAGT CATCTCTGCA GAAAAGGTAT 
ACCACGAGCA GCTGTTGGTG GCAGAGATTA CCAATGCCTG CTTTGAGCCT GCCAACCAGA 
TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001342150.1
CDS	166..891
Translation	MRHQQTERQDPSQPLSRQHGTYRQIFHPEQLITGKEDAANNYAWGHYTIGKEFIDLLLDRIRKLADQCTGLQGFLVFHSLGRGTGSDVTSFLMEWLSVNYGKKSKLGFSIYPAPQVSTAMVQPYNSILTTHTTLEHSDCAFMVDNKAIYDICHCNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVSYLTSTSPWPPMHQSSLQKRYTTSSCWWQRLPMPALSLPTRW

Target ORF information:

RefSeq Version	NM_001355221.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tubulin alpha 4b (TUBA4B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001355221.1

ORF Insert Sequence:

ATGCGGCACC AGCAGACAGA GAGACAAGAC CCCAGCCAGC CCCTGTCCAG GCAGCATGGC 
ACATACCGCC AGATCTTCCA TCCAGAGCAG CTCATCACAG GCAAGGAAGA TGCTGCCAAT 
AACTATGCCT GGGGCCACTA CACCATTGGG AAGGAGTTCA TCGACCTGCT ACTGGACCGG 
ATTCGGAAGC TGGCTGACCA GTGCACAGGA CTTCAGGGCT TCCTGGTGTT CCACAGCCTT 
GGTCGGGGCA CTGGCTCTGA CGTCACCTCA TTCCTGATGG AGTGGCTTTC TGTTAACTAT 
GGCAAGAAAT CCAAGCTGGG ATTCTCCATC TACCCAGCCC CCCAGGTGTC TACAGCCATG 
GTCCAGCCCT ACAACTCTAT CCTGACCACC CACACCACCC TGGAGCACTC AGACTGTGCC 
TTCATGGTGG ACAACAAAGC AATCTATGAC ATCTGCCACT GCAACCTAGA CATCGAGCGC 
CCAACCTACA CCAACCTCAA TCGCCTCATT AGCCAAATTG TCTCCTCCAT CACAGCTTCT 
CTGCGCTTTG ACGGGGCCCT CAATGTGGAC CTGACAGAGT TCCAGACCAA CCTGGTGTCC 
TACCTCACAT CCACTTCCCC CTGGCCACCT ATGCACCAGT CATCTCTGCA GAAAAGGTAT 
ACCACGAGCA GCTGTTGGTG GCAGAGATTA CCAATGCCTG CTTTGAGCCT GCCAACCAGA 
TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Low Expression LncRNA TUBA4B is a Poor Predictor of Prognosis and Regulates Cell Proliferation in Non-Small Cell Lung Cancer.
Pathology oncology research : POR23(2)265-270(2017 Apr)
Chen J,Hu L,Wang J,Zhang F,Chen J,Xu G,Wang Y,Pan Q

Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes.
Molecular and cellular biology6(7)2409-19(1986 Jul)
Villasante A,Wang D,Dobner P,Dolph P,Lewis SA,Cowan NJ