Gene Symbol | MUC5B |
Entrez Gene ID | 727897 |
Full Name | mucin 5B, oligomeric mucus/gel-forming |
Synonyms | MG1,MUC-5B,MUC5,MUC9 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]. |
Disorder MIM: | |
Disorder Html: | {Pulmonary fibrosis, idiopathic, susceptibility to}, 178500 (3) |