XAGE1A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	XAGE1A
Entrez Gene ID	653220
Full Name	X antigen family member 1A
Synonyms	CT12.1,CT12.1A,CT12.1B,CTP9,GAGED2,XAGE-1,XAGE1,XAGE1B
General protein information	Preferred Names X antigen family member 1A Names X antigen family member 1 G antigen family D member 2 G antigen, family D, 2 X antigen family member 1B cancer/testis antigen 12.1 cancer/testis antigen family 12, member 1a cancer/testis antigen family 12, member 1b cancer/testis associated protein protein XAGE-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.22
Summary	This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene, in addition to alternative transcription start sites, results in multiple transcript variants. [provided by RefSeq, Jan 2010].
Disorder MIM:	300742

mRNA and Protein(s)

mRNA	Protein	Name
NM_001097596.3	NP_001091065.1	X antigen family member 1 isoform d
NM_001097594.3	NP_001091063.2	X antigen family member 1 isoform a
XM_017029749.1	XP_016885238.1	X antigen family member 1 isoform X2
NM_001097596.2	NP_001091065.1	X antigen family member 1 isoform d
XM_017029748.1	XP_016885237.1	X antigen family member 1 isoform X1
NM_001097594.2	NP_001091063.2	X antigen family member 1 isoform a

Pathways from BioSystems

Homologies

Homo sapiens (human)	XAGE1B	NP_001091063.2
Homo sapiens (human)	XAGE1E	NP_001091073.2

Gene Ontology
Bibliography

Related articles in PubMed

[Cancer-testis genes in colon cancer].
Hilal NR, Novikov DV, Novikov VV, Karaulov AV
Terapevticheskii arkhiv89(5)113-117(2017)

Immune Responses to the Cancer Testis Antigen XAGE-1b in Non Small Cell Lung Cancer Caucasian Patients.
Saito K, Nakayama E, Valmori D
PloS one11(3)e0150623(2016)

Genetic variants of immunoglobulin ? and ? chains influence humoral immunity to the cancer-testis antigen XAGE-1b (GAGED2a) in patients with non-small cell lung cancer.
Pandey JP, Namboodiri AM, Ohue Y, Oka M, Nakayama E
Clinical and experimental immunology176(1)78-83(2014 Apr)

Identification of XAGE-1 isoforms: predominant expression of XAGE-1b in testis and tumors.
Sato S, Noguchi Y, Ohara N, Uenaka A, Shimono M, Nakagawa K, Koizumi F, Ishida T, Yoshino T, Shiratori Y, Nakayama E
Cancer immunity75(2007 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In patients with Colon cancer, the expression of XAGE-1 gene was related to a favorable prognosis.
Title: [Cancer-testis genes in colon cancer].

Strong immune responses to the cancer testis antigen XAGE-1b have been found in non-small cell lung cancer Caucasian patients.
Title: Immune Responses to the Cancer Testis Antigen XAGE-1b in Non Small Cell Lung Cancer Caucasian Patients.

Data indicate the involvement of immunoglobulin allotypes immunoglobulin gamma and kappa chains in immunity to a cancer-testis antigen, which has important implications for XAGE-1b-based immunotherapeutic interventions in lung adenocarcinoma.
Title: Genetic variants of immunoglobulin ? and ? chains influence humoral immunity to the cancer-testis antigen XAGE-1b (GAGED2a) in patients with non-small cell lung cancer.

XAGE-1b gene was able to influence angiogenesis directly or indirectly, leading to tumorigenesis and metastasis of ACC.
Title: Promoting effects on the proliferation and metastasis of ACC tumor cell with XAGE-1b overexpression.

Our results suggest that GAGE, XAGE1 and SSX4 might each have a role in melanoma progression
Title: Effects of CT-Xp gene knock down in melanoma cell lines.

The following XAGE1A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XAGE1A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22080	NM_001097594.3 Latest version!	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant a, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu16097	NM_001097596.3 Latest version!	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant d, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu99432	XM_017029748.1 Latest version!	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu99433	XM_017029749.1 Latest version!	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu16097	NM_001097596.2	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant d, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu22080	NM_001097594.2	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant a, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

XAGE1A ( NM_001097594.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001091063.2 Homo sapiens X antigen family member 1A (XAGE1A), transcript variant a, mRNA.

Price & Availability↑

CloneID	OHu22080
Clone ID Related Accession (Same CDS sequence)	NM_001097594.3 , NM_001097594.2
Accession Version	NM_001097594.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 246bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	X antigen family member 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX510359.5. On May 17, 2019 this sequence version replaced NM_001097594.2. Transcript Variant: This variant (a, also known as XAGE-1a) encodes the longer isoform (a, also known as isoform XAGE-1b). This variant also includes a major downstream transcription start site, which results in the variant referred to as XAGE-1b in the literature. Both XAGE-1a and XAGE-1b encode the same isoform. This RefSeq contains an in-frame start site 65 codons upstream from the currently annotated site but is not being annotated as a start site since it is in a weak Kozak sequence context and experimental evidence indicates that the downstream AUG is used. (PMID: 12479262 and PMID: 17335148). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX101350.1, AJ290447.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375602.2/ ENSP00000364752.1 RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGAGCC CCAAAAAGAA GAACCAGCAG CTGAAAGTCG GGATCCTACA CCTGGGCAGC 
AGACAGAAGA AGATCAGGAT ACAGCTGAGA TCCCAGTGCG CGACATGGAA GGTGATCTGC 
AAGAGCTGCA TCAGTCAAAC ACCGGGGATA AATCTGGATT TGGGTTCCGG CGTCAAGGTG 
AAGATAATAC CTAAAGAGGA ACACTGTAAA ATGCCAGAAG CAGGTGAAGA GCAACCACAA 
GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091063.2
CDS	149..394
Translation	MESPKKKNQQLKVGILHLGSRQKKIRIQLRSQCATWKVICKSCISQTPGINLDLGSGVKVKIIPKEEHCKMPEAGEEQPQV

Target ORF information:

RefSeq Version	NM_001097594.3
Organism	Homo sapiens(human)
Definition	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant a, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001097594.3

ORF Insert Sequence:

ATGGAGAGCC CCAAAAAGAA GAACCAGCAG CTGAAAGTCG GGATCCTACA CCTGGGCAGC 
AGACAGAAGA AGATCAGGAT ACAGCTGAGA TCCCAGTGCG CGACATGGAA GGTGATCTGC 
AAGAGCTGCA TCAGTCAAAC ACCGGGGATA AATCTGGATT TGGGTTCCGG CGTCAAGGTG 
AAGATAATAC CTAAAGAGGA ACACTGTAAA ATGCCAGAAG CAGGTGAAGA GCAACCACAA 
GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XAGE1A ( NM_001097594.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001091063.2 Homo sapiens X antigen family member 1A (XAGE1A), transcript variant a, mRNA.

Price & Availability↑

CloneID	OHu22080
Clone ID Related Accession (Same CDS sequence)	NM_001097594.3 , NM_001097594.2
Accession Version	NM_001097594.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 246bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	X antigen family member 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX510359.5. On Jan 20, 2010 this sequence version replaced NM_001097594.1. Transcript Variant: This variant (a, also known as XAGE-1a) encodes the longer isoform (a, also known as isoform XAGE-1b). This variant also includes a major downstream transcription start site, which results in the variant referred to as XAGE-1b in the literature. Both XAGE-1a and XAGE-1b encode the same isoform. This RefSeq contains an in-frame start site 65 codons upstream from the currently annotated site but is not being annotated as a start site since it is in a weak Kozak sequence context and experimental evidence indicates that the downstream AUG is used. (PMID: 12479262 and PMID: 17335148). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ290447.1, HY029077.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:12479262) ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGAGCC CCAAAAAGAA GAACCAGCAG CTGAAAGTCG GGATCCTACA CCTGGGCAGC 
AGACAGAAGA AGATCAGGAT ACAGCTGAGA TCCCAGTGCG CGACATGGAA GGTGATCTGC 
AAGAGCTGCA TCAGTCAAAC ACCGGGGATA AATCTGGATT TGGGTTCCGG CGTCAAGGTG 
AAGATAATAC CTAAAGAGGA ACACTGTAAA ATGCCAGAAG CAGGTGAAGA GCAACCACAA 
GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091063.2
CDS	289..534
Translation	MESPKKKNQQLKVGILHLGSRQKKIRIQLRSQCATWKVICKSCISQTPGINLDLGSGVKVKIIPKEEHCKMPEAGEEQPQV

Target ORF information:

RefSeq Version	NM_001097594.2
Organism	Homo sapiens(human)
Definition	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant a, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001097594.2

ORF Insert Sequence:

ATGGAGAGCC CCAAAAAGAA GAACCAGCAG CTGAAAGTCG GGATCCTACA CCTGGGCAGC 
AGACAGAAGA AGATCAGGAT ACAGCTGAGA TCCCAGTGCG CGACATGGAA GGTGATCTGC 
AAGAGCTGCA TCAGTCAAAC ACCGGGGATA AATCTGGATT TGGGTTCCGG CGTCAAGGTG 
AAGATAATAC CTAAAGAGGA ACACTGTAAA ATGCCAGAAG CAGGTGAAGA GCAACCACAA 
GTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XAGE1A ( NM_001097596.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001091065.1 Homo sapiens X antigen family member 1A (XAGE1A), transcript variant d, mRNA.

Price & Availability↑

CloneID	OHu16097
Clone ID Related Accession (Same CDS sequence)	NM_001097596.3 , NM_001097596.2
Accession Version	NM_001097596.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 210bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-17
Organism	Homo sapiens(human)
Product	X antigen family member 1 isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX510359.5. On May 31, 2019 this sequence version replaced NM_001097596.2. Transcript Variant: This variant (d, also known as XAGE-1d) starts at a downstream transcription start site, and uses an alternate splice site in an internal exon that causes a frameshift in the 3' coding region, compared to variant a. The encoded isoform (d) has a distinct and shorter C-terminus, compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138512.420946.1, DRR138512.23742.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGAGCC CCAAAAAGAA GAACCAGCAG CTGAAAGTCG GGATCCTACA CCTGGGCAGC 
AGACAGAAGA AGATCAGGAT ACAGCTGAGA TCCCAGGTGC TGGGAAGGGA AATGCGCGAC 
ATGGAAGGTG ATCTGCAAGA GCTGCATCAG TCAAACACCG GGGATAAATC TGGATTTGGG 
TTCCGGCGTC AAGGTGAAGA TAATACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091065.1
CDS	149..358
Translation	MESPKKKNQQLKVGILHLGSRQKKIRIQLRSQVLGREMRDMEGDLQELHQSNTGDKSGFGFRRQGEDNT

Target ORF information:

RefSeq Version	NM_001097596.3
Organism	Homo sapiens(human)
Definition	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant d, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001097596.3

ORF Insert Sequence:

ATGGAGAGCC CCAAAAAGAA GAACCAGCAG CTGAAAGTCG GGATCCTACA CCTGGGCAGC 
AGACAGAAGA AGATCAGGAT ACAGCTGAGA TCCCAGGTGC TGGGAAGGGA AATGCGCGAC 
ATGGAAGGTG ATCTGCAAGA GCTGCATCAG TCAAACACCG GGGATAAATC TGGATTTGGG 
TTCCGGCGTC AAGGTGAAGA TAATACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XAGE1A ( NM_001097596.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001091065.1 Homo sapiens X antigen family member 1A (XAGE1A), transcript variant d, mRNA.

Price & Availability↑

CloneID	OHu16097
Clone ID Related Accession (Same CDS sequence)	NM_001097596.3 , NM_001097596.2
Accession Version	NM_001097596.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 210bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	X antigen family member 1 isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX510359.5. On Jan 20, 2010 this sequence version replaced NM_001097596.1. Transcript Variant: This variant (d, also known as XAGE-1d) starts at a downstream transcription start site, and uses an alternate splice site in an internal exon that causes a frameshift in the 3' coding region, compared to variant a. The encoded isoform (d) has a distinct and shorter C-terminus, compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGAGAGCC CCAAAAAGAA GAACCAGCAG CTGAAAGTCG GGATCCTACA CCTGGGCAGC 
AGACAGAAGA AGATCAGGAT ACAGCTGAGA TCCCAGGTGC TGGGAAGGGA AATGCGCGAC 
ATGGAAGGTG ATCTGCAAGA GCTGCATCAG TCAAACACCG GGGATAAATC TGGATTTGGG 
TTCCGGCGTC AAGGTGAAGA TAATACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091065.1
CDS	136..345
Translation	MESPKKKNQQLKVGILHLGSRQKKIRIQLRSQVLGREMRDMEGDLQELHQSNTGDKSGFGFRRQGEDNT

Target ORF information:

RefSeq Version	NM_001097596.2
Organism	Homo sapiens(human)
Definition	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant d, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001097596.2

ORF Insert Sequence:

ATGGAGAGCC CCAAAAAGAA GAACCAGCAG CTGAAAGTCG GGATCCTACA CCTGGGCAGC 
AGACAGAAGA AGATCAGGAT ACAGCTGAGA TCCCAGGTGC TGGGAAGGGA AATGCGCGAC 
ATGGAAGGTG ATCTGCAAGA GCTGCATCAG TCAAACACCG GGGATAAATC TGGATTTGGG 
TTCCGGCGTC AAGGTGAAGA TAATACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XAGE1A ( XM_017029748.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885237.1 Homo sapiens X antigen family member 1A (XAGE1A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu99432
Clone ID Related Accession (Same CDS sequence)	XM_017029748.1
Accession Version	XM_017029748.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 447bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	X antigen family member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGTGCC ACGCCCATGG ACCTTCTTGT CTCGTCACGG CCATAACTAG GGAGGAAGGA 
GGGCCGAGGA GTGGAGGGGC TCAGGCGAAG CTGGGGTGCT GTTGGGGGTA TCCGAGTCCC 
AGAAGCACCT GGAACCCCGA CAGAAGATTC TGGACTCCCC AGACGGGACC AGGAGAGGGA 
CGGCATGAGC GACACACACA AACACAGAAC CACACAGCCA GTCCCAGGAG CCCAGTAATG 
GAGAGCCCCA AAAAGAAGAA CCAGCAGCTG AAAGTCGGGA TCCTACACCT GGGCAGCAGA 
CAGAAGAAGA TCAGGATACA GCTGAGATCC CAGGTGCTGG GAAGGGAAAT GCGCGACATG 
GAAGGTGATC TGCAAGAGCT GCATCAGTCA AACACCGGGG ATAAATCTGG ATTTGGGTTC 
CGGCGTCAAG GTGAAGATAA TACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885237.1
CDS	168..614
Translation	MRCHAHGPSCLVTAITREEGGPRSGGAQAKLGCCWGYPSPRSTWNPDRRFWTPQTGPGEGRHERHTQTQNHTASPRSPVMESPKKKNQQLKVGILHLGSRQKKIRIQLRSQVLGREMRDMEGDLQELHQSNTGDKSGFGFRRQGEDNT

Target ORF information:

RefSeq Version	XM_017029748.1
Organism	Homo sapiens(human)
Definition	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029748.1

ORF Insert Sequence:

ATGCGGTGCC ACGCCCATGG ACCTTCTTGT CTCGTCACGG CCATAACTAG GGAGGAAGGA 
GGGCCGAGGA GTGGAGGGGC TCAGGCGAAG CTGGGGTGCT GTTGGGGGTA TCCGAGTCCC 
AGAAGCACCT GGAACCCCGA CAGAAGATTC TGGACTCCCC AGACGGGACC AGGAGAGGGA 
CGGCATGAGC GACACACACA AACACAGAAC CACACAGCCA GTCCCAGGAG CCCAGTAATG 
GAGAGCCCCA AAAAGAAGAA CCAGCAGCTG AAAGTCGGGA TCCTACACCT GGGCAGCAGA 
CAGAAGAAGA TCAGGATACA GCTGAGATCC CAGGTGCTGG GAAGGGAAAT GCGCGACATG 
GAAGGTGATC TGCAAGAGCT GCATCAGTCA AACACCGGGG ATAAATCTGG ATTTGGGTTC 
CGGCGTCAAG GTGAAGATAA TACCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XAGE1A ( XM_017029749.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016885238.1 Homo sapiens X antigen family member 1A (XAGE1A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu99433
Clone ID Related Accession (Same CDS sequence)	XM_017029749.1
Accession Version	XM_017029749.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 441bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	X antigen family member 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCCTTT GGTGCCCACC TCAGTGCGCA TGTTCACTGG GCGTCTTCCC ATCGGCCCCT 
TCGCCAGTGT GGGGAACGCG GCGGAGCTGT GAGCCGGCGA CTCGGGTCCC TGAGGTCTGG 
ATTCTTTCTC CGCTACTGAG ACACGGCGGA CACACACAAA CACAGAACCA CACAGCCAGT 
CCCAGGAGCC CAGTAATGGA GAGCCCCAAA AAGAAGAACC AGCAGCTGAA AGTCGGGATC 
CTACACCTGG GCAGCAGACA GAAGAAGATC AGGATACAGC TGAGATCCCA GTGCGCGACA 
TGGAAGGTGA TCTGCAAGAG CTGCATCAGT CAAACACCGG GGATAAATCT GGATTTGGGT 
TCCGGCGTCA AGGTGAAGAT AATACCTAAA GAGGAACACT GTAAAATGCC AGAAGCAGGT 
GAAGAGCAAC CACAAGTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016885238.1
CDS	94..534
Translation	MLLWCPPQCACSLGVFPSAPSPVWGTRRSCEPATRVPEVWILSPLLRHGGHTQTQNHTASPRSPVMESPKKKNQQLKVGILHLGSRQKKIRIQLRSQCATWKVICKSCISQTPGINLDLGSGVKVKIIPKEEHCKMPEAGEEQPQV

Target ORF information:

RefSeq Version	XM_017029749.1
Organism	Homo sapiens(human)
Definition	Homo sapiens X antigen family member 1A (XAGE1A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029749.1

ORF Insert Sequence:

ATGCTCCTTT GGTGCCCACC TCAGTGCGCA TGTTCACTGG GCGTCTTCCC ATCGGCCCCT 
TCGCCAGTGT GGGGAACGCG GCGGAGCTGT GAGCCGGCGA CTCGGGTCCC TGAGGTCTGG 
ATTCTTTCTC CGCTACTGAG ACACGGCGGA CACACACAAA CACAGAACCA CACAGCCAGT 
CCCAGGAGCC CAGTAATGGA GAGCCCCAAA AAGAAGAACC AGCAGCTGAA AGTCGGGATC 
CTACACCTGG GCAGCAGACA GAAGAAGATC AGGATACAGC TGAGATCCCA GTGCGCGACA 
TGGAAGGTGA TCTGCAAGAG CTGCATCAGT CAAACACCGG GGATAAATCT GGATTTGGGT 
TCCGGCGTCA AGGTGAAGAT AATACCTAAA GAGGAACACT GTAAAATGCC AGAAGCAGGT 
GAAGAGCAAC CACAAGTTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

[Cancer-testis genes in colon cancer].
Terapevticheskii arkhiv89(5)113-117(2017)
Hilal NR,Novikov DV,Novikov VV,Karaulov AV

Immune Responses to the Cancer Testis Antigen XAGE-1b in Non Small Cell Lung Cancer Caucasian Patients.
PloS one11(3)e0150623(2016)
Saito K,Nakayama E,Valmori D

Genetic variants of immunoglobulin ? and ? chains influence humoral immunity to the cancer-testis antigen XAGE-1b (GAGED2a) in patients with non-small cell lung cancer.
Clinical and experimental immunology176(1)78-83(2014 Apr)
Pandey JP,Namboodiri AM,Ohue Y,Oka M,Nakayama E

Identification of XAGE-1 isoforms: predominant expression of XAGE-1b in testis and tumors.
Cancer immunity75(2007 Mar)
Sato S,Noguchi Y,Ohara N,Uenaka A,Shimono M,Nakagawa K,Koizumi F,Ishida T,Yoshino T,Shiratori Y,Nakayama E

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XAGE1A cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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