PKIB cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PKIB
Entrez Gene ID	5570
Full Name	cAMP-dependent protein kinase inhibitor beta
Synonyms	PRKACN2
General protein information	Preferred Names cAMP-dependent protein kinase inhibitor beta Names cAMP-dependent protein kinase inhibitor beta PKI-beta cAMP-dependent protein kinase inhibitor 2 protein kinase (cAMP-dependent, catalytic) inhibitor beta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6q22.31
Summary	This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
Disorder MIM:	606914

mRNA and Protein(s)

mRNA	Protein	Name
XM_011535933.2	XP_011534235.1	cAMP-dependent protein kinase inhibitor beta isoform X1
XM_011535935.1	XP_011534237.1	cAMP-dependent protein kinase inhibitor beta isoform X1
NM_001270394.1	NP_001257323.1	cAMP-dependent protein kinase inhibitor beta isoform 2
NM_032471.5	NP_115860.1	cAMP-dependent protein kinase inhibitor beta isoform 1
XM_011535930.2	XP_011534232.1	cAMP-dependent protein kinase inhibitor beta isoform X1
XM_011535932.2	XP_011534234.1	cAMP-dependent protein kinase inhibitor beta isoform X1
NM_001270395.1	NP_001257324.1	cAMP-dependent protein kinase inhibitor beta isoform 2
XM_011535937.2	XP_011534239.1	cAMP-dependent protein kinase inhibitor beta isoform X2
XM_011535934.2	XP_011534236.1	cAMP-dependent protein kinase inhibitor beta isoform X1
XM_011535930.3	XP_011534232.1	cAMP-dependent protein kinase inhibitor beta isoform X1
XM_011535931.2	XP_011534233.1	cAMP-dependent protein kinase inhibitor beta isoform X1
NM_181795.2	NP_861460.1	cAMP-dependent protein kinase inhibitor beta isoform 1
XM_011535933.3	XP_011534235.1	cAMP-dependent protein kinase inhibitor beta isoform X1
XM_011535935.2	XP_011534237.1	cAMP-dependent protein kinase inhibitor beta isoform X2
XM_011535937.1	XP_011534239.1	cAMP-dependent protein kinase inhibitor beta isoform X1
NM_181795.3	NP_861460.1	cAMP-dependent protein kinase inhibitor beta isoform 1
NM_181794.2	NP_861459.1	cAMP-dependent protein kinase inhibitor beta isoform 1
NM_001270393.1	NP_001257322.1	cAMP-dependent protein kinase inhibitor beta isoform 1
XM_011535931.3	XP_011534233.1	cAMP-dependent protein kinase inhibitor beta isoform X1
XM_011535932.3	XP_011534234.1	cAMP-dependent protein kinase inhibitor beta isoform X1
XM_011535936.1	XP_011534238.1	cAMP-dependent protein kinase inhibitor beta isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PKIB	XP_003311505.1
Homo sapiens (human)	PKIB	NP_001257323.1
	PKIB	XP_002803960.1
Canis lupus familiaris (dog)	PKIB	XP_005615660.1
Bos taurus (cattle)	PKIB	NP_001107990.1
Mus musculus (house mouse)	Pkib	NP_032889.3
Rattus norvegicus (Norway rat)	Pkib	NP_001070021.1

Gene Ontology
Bibliography

Related articles in PubMed

PKIB promotes cell proliferation and the invasion-metastasis cascade through the PI3K/Akt pathway in NSCLC cells.
Dou P, Zhang D, Cheng Z, Zhou G, Zhang L
Experimental biology and medicine (Maywood, N.J.)241(17)1911-1918(2016 11)

Protein kinase inhibitor ? enhances the constitutive activity of G-protein-coupled zinc receptor GPR39.
Kovacs Z, Schacht T, Herrmann AK, Albrecht P, Lefkimmiatis K, Methner A
The Biochemical journal462(1)125-32(2014 Aug)

PKIB expression strongly correlated with phosphorylated Akt expression in breast cancers and also with triple-negative breast cancer subtype.
Dabanaka K, Chung S, Nakagawa H, Nakamura Y, Okabayashi T, Sugimoto T, Hanazaki K, Furihata M
Medical molecular morphology45(4)229-33(2012 Dec)

High-throughput RNAi screening reveals novel regulators of telomerase.
Cerone MA, Burgess DJ, Naceur-Lombardelli C, Lord CJ, Ashworth A
Cancer research71(9)3328-40(2011 May)

Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways.
Chung S, Furihata M, Tamura K, Uemura M, Daigo Y, Nasu Y, Miki T, Shuin T, Fujioka T, Nakamura Y, Nakagawa H
Oncogene28(32)2849-59(2009 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results indicate that PKIB promotes cell proliferation and tumorigenesis by activating the PI3K/Akt pathway in non-small cell lung cancer (NSCLC), implying that this is an important underlying mechanism that affects the progression of NSCLC
Title: PKIB promotes cell proliferation and the invasion-metastasis cascade through the PI3K/Akt pathway in NSCLC cells.

mutation of the pseudosubstrate domain abolished the inhibitory activity of PKIB on protein kinase A activity, but had no effect on the interaction with GPR39, cell protection and induction of SRE-dependent transcription
Title: Protein kinase inhibitor ? enhances the constitutive activity of G-protein-coupled zinc receptor GPR39.

PKIB overexpression was strongly correlated with pAkt expression and triple-negative breast cancer, suggesting that PKIB overexpression might contribute to the tumor behavior and development of breast cancers.
Title: PKIB expression strongly correlated with phosphorylated Akt expression in breast cancers and also with triple-negative breast cancer subtype.

Findings show that PKIB and PKA-C kinase can have critical functions of aggressive phenotype of PCs through Akt phosphorylation and that they should be a promising molecular target for PC treatment.
Title: Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways.

PKIbeta may be a novel full-length gene related to human glioma and may provide a new way to gene therapy of glioma.
Title: [Expression and characterizations of a novel full-length gene PKIbeta related to human glioma].

The following PKIB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PKIB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08177	NM_181795.3 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08177	NM_032471.5 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08177	NM_181794.2 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08177	NM_001270393.1 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08177	XM_011535937.2 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08177	XM_011535935.2 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08177	XM_011535936.1 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu07734	NM_001270395.1 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu07734	NM_001270394.1 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu07734	XM_011535930.3 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu07734	XM_011535931.3 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu07734	XM_011535934.2 Latest version!	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu07734	XM_011535933.3 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu07734	XM_011535932.3 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu07734	XM_011535930.2	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu07734	XM_011535933.2	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu08177	XM_011535935.1	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08177	XM_011535937.1	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08177	NM_181795.2	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu07734	XM_011535931.2	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu07734	XM_011535932.2	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PKIB ( NM_032471.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_115860.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	NM_032471.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-23
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP260889.1, BC036011.1, AL512283.12 and BU753807.1. On Jul 4, 2012 this sequence version replaced NM_032471.4. Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3 and 4 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.1325.1, BC036011.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115860.1
CDS	398..634
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	NM_032471.5
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032471.5

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( NM_181795.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_861460.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	NM_181795.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP260889.1, AK315151.1, AL512283.12 and BU753807.1. On Jul 4, 2012 this sequence version replaced NM_181795.1. Transcript Variant: This variant (1) encodes the shorter isoform (1). Variants 1, 2, 3 and 4 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.230739.1, SRR1660805.59582.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_861460.1
CDS	465..701
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	NM_181795.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181795.2

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( NM_181795.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_861460.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	NM_181795.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP260889.1, AK315151.1, AL512283.12 and BU753807.1. On Nov 23, 2018 this sequence version replaced NM_181795.2. Transcript Variant: This variant (1) encodes the shorter isoform (1). Variants 1, 2, 3 and 4 encode the same isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.356684.1, SRR3476690.779839.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000368452.7/ ENSP00000357437.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_861460.1
CDS	292..528
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	NM_181795.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181795.3

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( NM_181794.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_861459.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	NM_181794.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG507119.1, AJ420562.1, AL512283.12 and BU753807.1. On Jul 4, 2012 this sequence version replaced NM_181794.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3 and 4 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AJ420562.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149398, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_861459.1
CDS	462..698
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	NM_181794.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181794.2

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( NM_001270393.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257322.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	NM_001270393.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG507119.1, BM802552.1, BM969901.1, AL512283.12 and BU753807.1. Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. Variants 1, 2, 3 and 4 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BM802552.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2154529, SAMEA2159931 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257322.1
CDS	582..818
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	NM_001270393.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270393.1

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535935.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534237.1 Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	XM_011535935.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534237.1
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535935.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535935.1

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535937.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534239.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X7, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	XM_011535937.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535937.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534239.1
CDS	194..430
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535937.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535937.2

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535935.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534237.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	XM_011535935.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535935.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534237.1
CDS	27..263
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535935.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535935.2

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535937.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534239.1 Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X8, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	XM_011535937.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534239.1
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535937.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535937.1

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535936.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534238.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu08177
Clone ID Related Accession (Same CDS sequence)	XM_011535935.1 , NM_032471.5 , XM_011535937.2 , NM_181795.2 , XM_011535935.2 , XM_011535937.1 , NM_181795.3 , NM_181794.2 , NM_001270393.1 , XM_011535936.1
Accession Version	XM_011535936.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 237bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534238.1
CDS	28..264
Translation	MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535936.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535936.1

ORF Insert Sequence:

ATGAGGACAG ATTCATCAAA AATGACTGAC GTGGAGTCTG GGGTCGCCAA TTTTGCATCT 
TCAGCAAGGG CAGGCCGCCG GAATGCCTTA CCAGACATCC AGAGTTCAGC TGCCACAGAC 
GGAACCTCAG ATTTGCCCCT CAAACTGGAG GCTCTCTCCG TGAAGGAAGA TGCAAAAGAG 
AAAGATGAAA AAACAACACA AGACCAATTG GAAAAGCCTC AAAATGAAGA AAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( NM_001270394.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257323.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	NM_001270394.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG507119.1, BM802552.1, BC036011.1, AL512283.12 and BU753807.1. Transcript Variant: This variant (5) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. Variants 5 and 6 encode the same isoform (2), which is longer and has a distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BG507119.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149398, SAMEA2151119 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257323.1
CDS	502..759
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	NM_001270394.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270394.1

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( NM_001270395.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257324.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	NM_001270395.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP262756.1, BC036011.1, AL512283.12 and BU753807.1. Transcript Variant: This variant (6) differs in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. Variants 5 and 6 encode the same isoform (2), which is longer and has a distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK074397.1, BP262817.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257324.1
CDS	163..420
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	NM_001270395.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270395.1

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535933.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534235.1 Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535933.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535933.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534235.1
CDS	260..517
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535933.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535933.2

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535930.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534232.1 Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535930.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535930.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534232.1
CDS	554..811
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535930.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535930.2

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535932.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534234.1 Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535932.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535932.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534234.1
CDS	299..556
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535932.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535932.2

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535934.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534236.1 Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535934.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535934.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534236.1
CDS	131..388
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535934.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535934.2

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535930.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534232.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535930.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011535930.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534232.1
CDS	554..811
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535930.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535930.3

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535931.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534233.1 Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535931.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011535931.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534233.1
CDS	325..582
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535931.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor beta (PKIB), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535931.2

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535933.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534235.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535933.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011535933.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534235.1
CDS	654..911
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535933.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535933.3

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535931.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534233.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535931.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011535931.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534233.1
CDS	325..582
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535931.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535931.3

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIB ( XM_011535932.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011534234.1 Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X3, mRNA.

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CloneID	OHu07734
Clone ID Related Accession (Same CDS sequence)	XM_011535933.2 , NM_001270394.1 , XM_011535930.2 , XM_011535932.2 , NM_001270395.1 , XM_011535934.2 , XM_011535930.3 , XM_011535931.2 , XM_011535933.3 , XM_011535931.3 , XM_011535932.3
Accession Version	XM_011535932.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor beta isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011535932.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011534234.1
CDS	299..556
Translation	MSHQDVAMRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK

Target ORF information:

RefSeq Version	XM_011535932.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor beta (PKIB), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011535932.3

ORF Insert Sequence:

ATGTCACACC AGGATGTTGC TATGAGGACA GATTCATCAA AAATGACTGA CGTGGAGTCT 
GGGGTCGCCA ATTTTGCATC TTCAGCAAGG GCAGGCCGCC GGAATGCCTT ACCAGACATC 
CAGAGTTCAG CTGCCACAGA CGGAACCTCA GATTTGCCCC TCAAACTGGA GGCTCTCTCC 
GTGAAGGAAG ATGCAAAAGA GAAAGATGAA AAAACAACAC AAGACCAATT GGAAAAGCCT 
CAAAATGAAG AAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

PKIB promotes cell proliferation and the invasion-metastasis cascade through the PI3K/Akt pathway in NSCLC cells.
Experimental biology and medicine (Maywood, N.J.)241(17)1911-1918(2016 11)
Dou P,Zhang D,Cheng Z,Zhou G,Zhang L

Protein kinase inhibitor ? enhances the constitutive activity of G-protein-coupled zinc receptor GPR39.
The Biochemical journal462(1)125-32(2014 Aug)
Kovacs Z,Schacht T,Herrmann AK,Albrecht P,Lefkimmiatis K,Methner A

PKIB expression strongly correlated with phosphorylated Akt expression in breast cancers and also with triple-negative breast cancer subtype.
Medical molecular morphology45(4)229-33(2012 Dec)
Dabanaka K,Chung S,Nakagawa H,Nakamura Y,Okabayashi T,Sugimoto T,Hanazaki K,Furihata M

High-throughput RNAi screening reveals novel regulators of telomerase.
Cancer research71(9)3328-40(2011 May)
Cerone MA,Burgess DJ,Naceur-Lombardelli C,Lord CJ,Ashworth A

Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways.
Oncogene28(32)2849-59(2009 Aug)
Chung S,Furihata M,Tamura K,Uemura M,Daigo Y,Nasu Y,Miki T,Shuin T,Fujioka T,Nakamura Y,Nakagawa H

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PKIB cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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FAX

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