PPP3CC cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PPP3CC
Entrez Gene ID	5533
Full Name	protein phosphatase 3 catalytic subunit gamma
Synonyms	CALNA3,CNA3,PP2Bgamma
General protein information	Preferred Names protein phosphatase 3 catalytic subunit gamma Names serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform CAM-PRP catalytic subunit calcineurin, testis-specific catalytic subunit calmodulin-dependent calcineurin A subunit gamma isoform protein phosphatase 2B, catalytic subunit, gamma isoform protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform protein phosphatase 3, catalytic subunit, gamma isozyme
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8p21.3
Summary	Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Disorder MIM:	114107

mRNA and Protein(s)

mRNA	Protein	Name
XM_017013610.1	XP_016869099.1	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
XM_017013611.1	XP_016869100.1	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X2
NM_001243975.1	NP_001230904.1	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform 3
NM_001243974.1	NP_001230903.1	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform 1
XM_017013611.2	XP_016869100.1	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
NM_005605.4	NP_005596.2	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform 2

Pathways from BioSystems

Homologies

	PPP3CC	XP_001103623.1
Danio rerio (zebrafish)	ppp3ccb	NP_001074063.2
Homo sapiens (human)	PPP3CC	NP_001230903.1
Pan troglodytes (chimpanzee)	PPP3CC	XP_001155813.1
Canis lupus familiaris (dog)	PPP3CC	XP_851300.3
Danio rerio (zebrafish)	ppp3cca	NP_001160100.1
Xenopus tropicalis (tropical clawed frog)	ppp3cb	NP_001090755.1
Mus musculus (house mouse)	Ppp3cc	NP_032941.1
Bos taurus (cattle)	PPP3CC	NP_001091545.1
Rattus norvegicus (Norway rat)	Ppp3cc	NP_599194.1

Gene Ontology
Bibliography

Related articles in PubMed

Genetic Variations in the 3'-untranslated Regions of Genes Involved in the Cell Cycle and Apoptosis Pathways Affect Bladder Cancer Risk.
Zhang Q, Wang W, Xu W, Du` M, Ma G, Liu H, Chu H, Tong NA, Wang M, Shao J, Zhang Z, Yuan L, Qian J
Cancer genomics & proteomics15(1)67-72(2018 Jan-Feb)

Repression of the expression of PPP3CC by ZEB1 confers activation of NF-?B and contributes to invasion and growth in glioma cells.
Wang H, Zhao S, Chen B, Fu C, Dang Y, Fang P, Wang J, Wang N, Liu L
Japanese journal of clinical oncology(2017 Dec)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Variation in PPP3CC Genotype Is Associated with Long-Term Recovery after Severe Brain Injury.
Osier ND, Bales JW, Pugh B, Shin S, Wyrobek J, Puccio AM, Okonkwo DO, Ren D, Alexander S, Conley YP, Dixon CE
Journal of neurotrauma34(1)86-96(2017 Jan)

Calcineurin A? is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis.
Cottrell JR, Li B, Kyung JW, Ashford CJ, Mann JJ, Horvath TL, Ryan TA, Kim SH, Gerber DJ
The Journal of biological chemistry291(4)1948-56(2016 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The rs2443504 AA genotype was associated with the Glasgow coma score at 3, 6, and 12 months following severe brain injury.
Title: Variation in PPP3CC Genotype Is Associated with Long-Term Recovery after Severe Brain Injury.

Knockdown of CNAgamma leads to a disruption of synaptic vesicle cycling in hippocampal neurons.
Title: Calcineurin A? is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis.

The PPP3CC involved in the regulation of immune system and synaptic plasticity, seems promising for further investigation.
Title: PPP3CC gene: a putative modulator of antidepressant response through the B-cell receptor signaling pathway.

protein level of PPP3CC negatively correlates with the cellular level of IP3, suggesting a regulatory role of PPP3CC in the IP3-Ca2+ signaling pathway
Title: PPP3CC feedback regulates IP3-Ca2+ pathway through preventing ITPKC degradation.

study suggests that NMDA receptor-mediated signalling genes, DAO, PPP3CC, DTNBP1 might be involved in schizophrenia pathogenic mechanisms related to gender
Title: Schizophrenia susceptibility and NMDA-receptor mediated signalling: an association study involving 32 tagSNPs of DAO, DAOA, PPP3CC, and DTNBP1 genes.

The following PPP3CC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PPP3CC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55876	NM_005605.4 Latest version!	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu12531	NM_001243974.1 Latest version!	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu55919	NM_001243975.1 Latest version!	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu98091	XM_017013610.1 Latest version!	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu98092	XM_017013611.2 Latest version!	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu98092	XM_017013611.1	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PPP3CC ( NM_005605.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_005596.2 Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu55876
Clone ID Related Accession (Same CDS sequence)	NM_005605.4
Accession Version	NM_005605.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055013.1, BC004864.2, AY007249.1 and DB517138.1. On Sep 9, 2011 this sequence version replaced NM_005605.3. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.255155.1, SRR1803614.139753.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GGAAGCACTA CAGTTCGTAA GGAGATCATC AGGAATAAGA TCAGAGCCAT TGGGAAGATG 
GCACGGGTCT TTTCAATTCT TCGGCAAGAA AGTGAGAGTG TGCTGACTCT CAAGGGCCTG 
ACTCCCACAG GCACACTCCC TCTGGGCGTC CTCTCAGGAG GCAAGCAGAC TATCGAGACA 
GCCACAGTAG AAGCGGTAGA GGCCCGGGAA GCCATCAGAG GGTTCTCGCT TCAGCACAAG 
ATCCGGAGTT TTGAAGAAGC GCGAGGTCTG GACCGAATTA ATGAGCGAAT GCCACCCCGA 
AAGGATAGCA TACACGCTGG TGGGCCAATG AAATCTGTAA CCTCAGCACA CTCACATGCT 
GCGCACAGGA GCGACCAAGG GAAGAAAGCC CATTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005596.2
CDS	441..1979
Translation	MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS

Target ORF information:

RefSeq Version	NM_005605.4
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005605.4

ORF Insert Sequence:

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GGAAGCACTA CAGTTCGTAA GGAGATCATC AGGAATAAGA TCAGAGCCAT TGGGAAGATG 
GCACGGGTCT TTTCAATTCT TCGGCAAGAA AGTGAGAGTG TGCTGACTCT CAAGGGCCTG 
ACTCCCACAG GCACACTCCC TCTGGGCGTC CTCTCAGGAG GCAAGCAGAC TATCGAGACA 
GCCACAGTAG AAGCGGTAGA GGCCCGGGAA GCCATCAGAG GGTTCTCGCT TCAGCACAAG 
ATCCGGAGTT TTGAAGAAGC GCGAGGTCTG GACCGAATTA ATGAGCGAAT GCCACCCCGA 
AAGGATAGCA TACACGCTGG TGGGCCAATG AAATCTGTAA CCTCAGCACA CTCACATGCT 
GCGCACAGGA GCGACCAAGG GAAGAAAGCC CATTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP3CC ( NM_001243974.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001230903.1 Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12531
Clone ID Related Accession (Same CDS sequence)	NM_001243974.1
Accession Version	NM_001243974.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055013.1, AK299415.1, AC037459.16, AY007249.1 and DB517138.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299415.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151741, SAMEA2154361 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GATCACTACA TTCCAAGCTA TCAGAAAGGA AGCACTACAG TTCGTAAGGA GATCATCAGG 
AATAAGATCA GAGCCATTGG GAAGATGGCA CGGGTCTTTT CAATTCTTCG GCAAGAAAGT 
GAGAGTGTGC TGACTCTCAA GGGCCTGACT CCCACAGGCA CACTCCCTCT GGGCGTCCTC 
TCAGGAGGCA AGCAGACTAT CGAGACAGCC ACAGTAGAAG CGGTAGAGGC CCGGGAAGCC 
ATCAGAGGGT TCTCGCTTCA GCACAAGATC CGGAGTTTTG AAGAAGCGCG AGGTCTGGAC 
CGAATTAATG AGCGAATGCC ACCCCGAAAG GATAGCATAC ACGCTGGTGG GCCAATGAAA 
TCTGTAACCT CAGCACACTC ACATGCTGCG CACAGGAGCG ACCAAGGGAA GAAAGCCCAT 
TCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001230903.1
CDS	441..2006
Translation	MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELISDDEAEDHYIPSYQKGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS

Target ORF information:

RefSeq Version	NM_001243974.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001243974.1

ORF Insert Sequence:

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GATCACTACA TTCCAAGCTA TCAGAAAGGA AGCACTACAG TTCGTAAGGA GATCATCAGG 
AATAAGATCA GAGCCATTGG GAAGATGGCA CGGGTCTTTT CAATTCTTCG GCAAGAAAGT 
GAGAGTGTGC TGACTCTCAA GGGCCTGACT CCCACAGGCA CACTCCCTCT GGGCGTCCTC 
TCAGGAGGCA AGCAGACTAT CGAGACAGCC ACAGTAGAAG CGGTAGAGGC CCGGGAAGCC 
ATCAGAGGGT TCTCGCTTCA GCACAAGATC CGGAGTTTTG AAGAAGCGCG AGGTCTGGAC 
CGAATTAATG AGCGAATGCC ACCCCGAAAG GATAGCATAC ACGCTGGTGG GCCAATGAAA 
TCTGTAACCT CAGCACACTC ACATGCTGCG CACAGGAGCG ACCAAGGGAA GAAAGCCCAT 
TCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP3CC ( NM_001243975.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001230904.1 Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu55919
Clone ID Related Accession (Same CDS sequence)	NM_001243975.1
Accession Version	NM_001243975.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055013.1, S46622.1, AK299415.1, AY007249.1 and DB517138.1. Transcript Variant: This variant (3) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (3) lacks two alternate internal segments compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.168638.1, SRR1803617.152538.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GGAAGCACTA CAGTTCGTAA GGAGATCATC AGGAATAAGA TCAGAGCCAT TGGGAAGATG 
GCACGGGTCT TTTCAATTCT TCGGCAAGAA AGTGAGAGTG TGCTGACTCT CAAGGGCCTG 
ACTCCCACAG GCACACTCCC TCTGGGCGTC CTCTCAGGAG GCAAGCAGAC TATCGAGACA 
GCCATCAGAG GGTTCTCGCT TCAGCACAAG ATCCGGAGTT TTGAAGAAGC GCGAGGTCTG 
GACCGAATTA ATGAGCGAAT GCCACCCCGA AAGGATAGCA TACACGCTGG TGGGCCAATG 
AAATCTGTAA CCTCAGCACA CTCACATGCT GCGCACAGGA GCGACCAAGG GAAGAAAGCC 
CATTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001230904.1
CDS	441..1949
Translation	MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLPLGVLSGGKQTIETAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS

Target ORF information:

RefSeq Version	NM_001243975.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001243975.1

ORF Insert Sequence:

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GGAAGCACTA CAGTTCGTAA GGAGATCATC AGGAATAAGA TCAGAGCCAT TGGGAAGATG 
GCACGGGTCT TTTCAATTCT TCGGCAAGAA AGTGAGAGTG TGCTGACTCT CAAGGGCCTG 
ACTCCCACAG GCACACTCCC TCTGGGCGTC CTCTCAGGAG GCAAGCAGAC TATCGAGACA 
GCCATCAGAG GGTTCTCGCT TCAGCACAAG ATCCGGAGTT TTGAAGAAGC GCGAGGTCTG 
GACCGAATTA ATGAGCGAAT GCCACCCCGA AAGGATAGCA TACACGCTGG TGGGCCAATG 
AAATCTGTAA CCTCAGCACA CTCACATGCT GCGCACAGGA GCGACCAAGG GAAGAAAGCC 
CATTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP3CC ( XM_017013610.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869099.1 Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X3, mRNA.

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CloneID	OHu98091
Clone ID Related Accession (Same CDS sequence)	XM_017013610.1
Accession Version	XM_017013610.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATAGAAG TAGATGCTCC AATCACAGTA TGTGGTGATA TTCATGGACA ATTCTTTGAC 
CTAATGAAGT TATTTGAAGT TGGAGGATCA CCTAGTAACA CACGCTACCT CTTTCTGGGT 
GACTATGTGG ACAGAGGCTA TTTCAGTATA GAGTGTGTGC TGTATTTATG GAGTTTAAAG 
ATTAATCATC CCAAAACATT GTTTCTGCTT CGGGGAAATC ATGAATGCAG GCATCTTACA 
GACTATTTCA CCTTCAAACA GGAATGTCGA ATCAAATATT CGGAACAGGT GTATGATGCC 
TGTATGGAGA CATTTGACTG TCTTCCTCTT GCTGCCCTCT TAAACCAGCA GTTTCTCTGT 
GTACATGGAG GAATGTCACC TGAAATTACT TCTTTAGATG ACATTAGGAA ATTAGACAGG 
TTTACGGAAC CTCCCGCCTT TGGACCTGTG TGTGACCTGC TTTGGTCTGA TCCCTCAGAG 
GATTATGGCA ATGAGAAGAC CTTGGAGCAC TATACCCACA ACACTGTCCG AGGGTGCTCT 
TATTTCTACA GTTACCCTGC AGTTTGTGAA TTTTTGCAGA ACAATAATTT ACTATCAATT 
ATCAGAGCCC ATGAAGCCCA AGATGCTGGG TATCGAATGT ACAGGAAGAG CCAAGCCACA 
GGCTTTCCAT CACTTATTAC AATTTTCTCT GCCCCCAATT ACCTAGATGT CTATAACAAT 
AAAGCTGCTG TGTTGAAATA TGAAAACAAT GTCATGAATA TCAGGCAGTT TAACTGTTCT 
CCACACCCCT ACTGGCTTCC AAACTTTATG GATGTTTTCA CATGGTCTTT GCCTTTTGTT 
GGGGAAAAAG TCACAGAGAT GCTGGTAAAT GTGCTCAACA TATGCTCTGA TGACGAACTG 
ATTTCTGATG ATGAAGCAGA AGGAAGCACT ACAGTTCGTA AGGAGATCAT CAGGAATAAG 
ATCAGAGCCA TTGGGAAGAT GGCACGGGTC TTTTCAATTC TTCGGCAAGA AAGTGAGAGT 
GTGCTGACTC TCAAGGGCCT GACTCCCACA GGCACACTCC CTCTGGGCGT CCTCTCAGGA 
GGCAAGCAGA CTATCGAGAC AGCCACAGTA GAAGCGGTAG AGGCCCGGGA AGCCATCAGA 
GGGTTCTCGC TTCAGCACAA GATCCGGAGT TTTGAAGAAG CGCGAGGTCT GGACCGAATT 
AATGAGCGAA TGCCACCCCG AAAGGATAGC ATACACGCTG GTGGGCCAAT GAAATCTGTA 
ACCTCAGCAC ACTCACATGC TGCGCACAGG AGCGACCAAG GGAAGAAAGC CCATTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869099.1
CDS	453..1772
Translation	MIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPRKDSIHAGGPMKSVTSAHSHAAHRSDQGKKAHS

Target ORF information:

RefSeq Version	XM_017013610.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013610.1

ORF Insert Sequence:

ATGATAGAAG TAGATGCTCC AATCACAGTA TGTGGTGATA TTCATGGACA ATTCTTTGAC 
CTAATGAAGT TATTTGAAGT TGGAGGATCA CCTAGTAACA CACGCTACCT CTTTCTGGGT 
GACTATGTGG ACAGAGGCTA TTTCAGTATA GAGTGTGTGC TGTATTTATG GAGTTTAAAG 
ATTAATCATC CCAAAACATT GTTTCTGCTT CGGGGAAATC ATGAATGCAG GCATCTTACA 
GACTATTTCA CCTTCAAACA GGAATGTCGA ATCAAATATT CGGAACAGGT GTATGATGCC 
TGTATGGAGA CATTTGACTG TCTTCCTCTT GCTGCCCTCT TAAACCAGCA GTTTCTCTGT 
GTACATGGAG GAATGTCACC TGAAATTACT TCTTTAGATG ACATTAGGAA ATTAGACAGG 
TTTACGGAAC CTCCCGCCTT TGGACCTGTG TGTGACCTGC TTTGGTCTGA TCCCTCAGAG 
GATTATGGCA ATGAGAAGAC CTTGGAGCAC TATACCCACA ACACTGTCCG AGGGTGCTCT 
TATTTCTACA GTTACCCTGC AGTTTGTGAA TTTTTGCAGA ACAATAATTT ACTATCAATT 
ATCAGAGCCC ATGAAGCCCA AGATGCTGGG TATCGAATGT ACAGGAAGAG CCAAGCCACA 
GGCTTTCCAT CACTTATTAC AATTTTCTCT GCCCCCAATT ACCTAGATGT CTATAACAAT 
AAAGCTGCTG TGTTGAAATA TGAAAACAAT GTCATGAATA TCAGGCAGTT TAACTGTTCT 
CCACACCCCT ACTGGCTTCC AAACTTTATG GATGTTTTCA CATGGTCTTT GCCTTTTGTT 
GGGGAAAAAG TCACAGAGAT GCTGGTAAAT GTGCTCAACA TATGCTCTGA TGACGAACTG 
ATTTCTGATG ATGAAGCAGA AGGAAGCACT ACAGTTCGTA AGGAGATCAT CAGGAATAAG 
ATCAGAGCCA TTGGGAAGAT GGCACGGGTC TTTTCAATTC TTCGGCAAGA AAGTGAGAGT 
GTGCTGACTC TCAAGGGCCT GACTCCCACA GGCACACTCC CTCTGGGCGT CCTCTCAGGA 
GGCAAGCAGA CTATCGAGAC AGCCACAGTA GAAGCGGTAG AGGCCCGGGA AGCCATCAGA 
GGGTTCTCGC TTCAGCACAA GATCCGGAGT TTTGAAGAAG CGCGAGGTCT GGACCGAATT 
AATGAGCGAA TGCCACCCCG AAAGGATAGC ATACACGCTG GTGGGCCAAT GAAATCTGTA 
ACCTCAGCAC ACTCACATGC TGCGCACAGG AGCGACCAAG GGAAGAAAGC CCATTCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP3CC ( XM_017013611.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869100.1 Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu98092
Clone ID Related Accession (Same CDS sequence)	XM_017013611.1 , XM_017013611.2
Accession Version	XM_017013611.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GATCACTACA TTCCAAGCTA TCAGAAAGGT ATCCGACTAA ACTGTGCTAA GAGCTTAATG 
CTTACTCTCT GTCCCACCAT AGTCTATTGG TTAGACTTAA AATTGGTAGT TGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869100.1
CDS	441..1697
Translation	MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELISDDEAEDHYIPSYQKGIRLNCAKSLMLTLCPTIVYWLDLKLVVE

Target ORF information:

RefSeq Version	XM_017013611.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013611.1

ORF Insert Sequence:

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GATCACTACA TTCCAAGCTA TCAGAAAGGT ATCCGACTAA ACTGTGCTAA GAGCTTAATG 
CTTACTCTCT GTCCCACCAT AGTCTATTGG TTAGACTTAA AATTGGTAGT TGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP3CC ( XM_017013611.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869100.1 Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu98092
Clone ID Related Accession (Same CDS sequence)	XM_017013611.1 , XM_017013611.2
Accession Version	XM_017013611.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013611.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GATCACTACA TTCCAAGCTA TCAGAAAGGT ATCCGACTAA ACTGTGCTAA GAGCTTAATG 
CTTACTCTCT GTCCCACCAT AGTCTATTGG TTAGACTTAA AATTGGTAGT TGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869100.1
CDS	358..1614
Translation	MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKIINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDCLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELISDDEAEDHYIPSYQKGIRLNCAKSLMLTLCPTIVYWLDLKLVVE

Target ORF information:

RefSeq Version	XM_017013611.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 3 catalytic subunit gamma (PPP3CC), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013611.2

ORF Insert Sequence:

ATGTCCGGGA GGCGCTTCCA CCTCTCCACC ACCGACCGCG TCATCAAAGC TGTCCCCTTT 
CCTCCAACCC AACGGCTTAC TTTCAAGGAA GTATTTGAGA ATGGGAAACC TAAAGTTGAT 
GTTTTAAAAA ACCATTTGGT AAAGGAAGGA CGACTGGAAG AGGAAGTAGC CTTAAAGATA 
ATCAATGATG GGGCTGCCAT CCTGAGGCAA GAGAAGACTA TGATAGAAGT AGATGCTCCA 
ATCACAGTAT GTGGTGATAT TCATGGACAA TTCTTTGACC TAATGAAGTT ATTTGAAGTT 
GGAGGATCAC CTAGTAACAC ACGCTACCTC TTTCTGGGTG ACTATGTGGA CAGAGGCTAT 
TTCAGTATAG AGTGTGTGCT GTATTTATGG AGTTTAAAGA TTAATCATCC CAAAACATTG 
TTTCTGCTTC GGGGAAATCA TGAATGCAGG CATCTTACAG ACTATTTCAC CTTCAAACAG 
GAATGTCGAA TCAAATATTC GGAACAGGTG TATGATGCCT GTATGGAGAC ATTTGACTGT 
CTTCCTCTTG CTGCCCTCTT AAACCAGCAG TTTCTCTGTG TACATGGAGG AATGTCACCT 
GAAATTACTT CTTTAGATGA CATTAGGAAA TTAGACAGGT TTACGGAACC TCCCGCCTTT 
GGACCTGTGT GTGACCTGCT TTGGTCTGAT CCCTCAGAGG ATTATGGCAA TGAGAAGACC 
TTGGAGCACT ATACCCACAA CACTGTCCGA GGGTGCTCTT ATTTCTACAG TTACCCTGCA 
GTTTGTGAAT TTTTGCAGAA CAATAATTTA CTATCAATTA TCAGAGCCCA TGAAGCCCAA 
GATGCTGGGT ATCGAATGTA CAGGAAGAGC CAAGCCACAG GCTTTCCATC ACTTATTACA 
ATTTTCTCTG CCCCCAATTA CCTAGATGTC TATAACAATA AAGCTGCTGT GTTGAAATAT 
GAAAACAATG TCATGAATAT CAGGCAGTTT AACTGTTCTC CACACCCCTA CTGGCTTCCA 
AACTTTATGG ATGTTTTCAC ATGGTCTTTG CCTTTTGTTG GGGAAAAAGT CACAGAGATG 
CTGGTAAATG TGCTCAACAT ATGCTCTGAT GACGAACTGA TTTCTGATGA TGAAGCAGAA 
GATCACTACA TTCCAAGCTA TCAGAAAGGT ATCCGACTAA ACTGTGCTAA GAGCTTAATG 
CTTACTCTCT GTCCCACCAT AGTCTATTGG TTAGACTTAA AATTGGTAGT TGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic Variations in the 3'-untranslated Regions of Genes Involved in the Cell Cycle and Apoptosis Pathways Affect Bladder Cancer Risk.
Cancer genomics & proteomics15(1)67-72(2018 Jan-Feb)
Zhang Q,Wang W,Xu W,Du` M,Ma G,Liu H,Chu H,Tong NA,Wang M,Shao J,Zhang Z,Yuan L,Qian J

Repression of the expression of PPP3CC by ZEB1 confers activation of NF-?B and contributes to invasion and growth in glioma cells.
Japanese journal of clinical oncology(2017 Dec)
Wang H,Zhao S,Chen B,Fu C,Dang Y,Fang P,Wang J,Wang N,Liu L

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Variation in PPP3CC Genotype Is Associated with Long-Term Recovery after Severe Brain Injury.
Journal of neurotrauma34(1)86-96(2017 Jan)
Osier ND,Bales JW,Pugh B,Shin S,Wyrobek J,Puccio AM,Okonkwo DO,Ren D,Alexander S,Conley YP,Dixon CE

Calcineurin A? is a Functional Phosphatase That Modulates Synaptic Vesicle Endocytosis.
The Journal of biological chemistry291(4)1948-56(2016 Jan)
Cottrell JR,Li B,Kyung JW,Ashford CJ,Mann JJ,Horvath TL,Ryan TA,Kim SH,Gerber DJ

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PPP3CC cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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