L1TD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	L1TD1
Entrez Gene ID	54596
Full Name	LINE1 type transposase domain containing 1
Synonyms	ECAT11
General protein information	Preferred Names LINE1 type transposase domain containing 1 Names LINE-1 type transposase domain-containing protein 1 ES cell-associated protein 11 LINE-1 type transposase domain containing 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p31.3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001164835.1	NP_001158307.1	LINE-1 type transposase domain-containing protein 1
NM_001164835.2	NP_001158307.1	LINE-1 type transposase domain-containing protein 1
NM_019079.4	NP_061952.3	LINE-1 type transposase domain-containing protein 1
NM_019079.5	NP_061952.3	LINE-1 type transposase domain-containing protein 1

Pathways from BioSystems

Homologies

	L1TD1	XP_001084821.1
Pan troglodytes (chimpanzee)	L1TD1	XP_001147032.2
Homo sapiens (human)	L1TD1	NP_001158307.1

Gene Ontology
Bibliography

Related articles in PubMed

SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers.
Altenberger C, Heller G, Ziegler B, Tomasich E, Marhold M, Topakian T, M?llauer L, Heffeter P, Lang G, End-Pf?tzenreuter A, D?me B, Arns BM, Klepetko W, Zielinski CC, Z?chbauer-M?ller S
Molecular cancer16(1)1(2017 01)

Embryonic Stem Cell-Related Protein L1TD1 Is Required for Cell Viability, Neurosphere Formation, and Chemoresistance in Medulloblastoma.
Santos MC, Silva PB, Rodini CO, Furukawa G, Marco Antonio DS, Zanotto-Filho A, Moreira JC, Okamoto OK
Stem cells and development24(22)2700-8(2015 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SPAG6 and L1TD1 are tumor-specifically methylated in NSCLCs and that DNA methylation is involved in the transcriptional regulation of these genes. Moreover, in vitro as well as in vivo experiments revealed tumor-cell growth suppressing properties of L1TD1 in NSCLC cells.
Title: SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers.

L1TD1 depletion reduced medulloblastoma cell viability, cell proliferation, downregulated expression of the neural stem cell markers and induced apoptosis.
Title: Embryonic Stem Cell-Related Protein L1TD1 Is Required for Cell Viability, Neurosphere Formation, and Chemoresistance in Medulloblastoma.

we show that L1TD1 is a part of the pluripotency interactome network of OCT4, SOX2, and NANOG, bridging nuclear and cytoplasmic regulation and highlighting the importance of RNA biology in pluripotency.
Title: The L1TD1 protein interactome reveals the importance of post-transcriptional regulation in human pluripotency.

L1TD1 may have become incorporated into pluripotency maintenance in some lineages.
Title: Positive selection and multiple losses of the LINE-1-derived L1TD1 gene in mammals suggest a dual role in genome defense and pluripotency.

LINE-1 methylation was evaluated, a statistical difference was seen amongst groups and a slight hypomethylated state in the AgP samples was observed.
Title: DNA methylation levels of SOCS1 and LINE-1 in oral epithelial cells from aggressive periodontitis patients.

The following L1TD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the L1TD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27206	NM_001164835.2 Latest version!	Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu27206	NM_019079.5 Latest version!	Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
View Old Accession Versions >>
OHu27206	NM_001164835.1	Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
OHu27206	NM_019079.4	Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$339.50-$475.30 $679.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

L1TD1 ( NM_001164835.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001158307.1 Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27206
Clone ID Related Accession (Same CDS sequence)	NM_001164835.1 , NM_001164835.2 , NM_019079.4 , NM_019079.5
Accession Version	NM_001164835.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2598bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	LINE-1 type transposase domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX167172.1, CX166941.1, DR005055.1, AK001973.1, AB211065.1, CN428323.1, BX382228.2 and BU677875.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AB211065.1, AL834314.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGATG TATCTACTAG TGTACAATCA AAATTTGCTA GACTTGCAAA GAAAAAGGAA 
AATATCACCT ATATGAAAAG AGAGCAGTTA ACAGAAACTG ATAAGGACAT AGCTCCGGTA 
TTAGATTTAA AATGCAAGGA CGTATCAGCA ATTATGAATA AGTTTAAGGT CTTAATGGAA 
ATTCAAGACC TGATGTTTGA GGAGATGAGG GAAACTCTTA AAAATGACCT AAAAGCAGTT 
TTAGGGGGAA AAGCTACAAT ACCTGAGGTA AAGAATTCAG AGAACTCCAG TAGTAGGACA 
GAGTTTCAGC AAATAATCAA TTTAGCATTA CAAAAAACAG GGATGGTAGG GAAAATAGAA 
GGAGAAAACT CTAAAATAGG TGATGATAAT GAAAATTTAA CCTTTAAATT AGAAGTAAAT 
GAGCTGAGTG GTAAATTAGA CAACACTAAC GAATACAATA GTAATGATGG TAAGAAATTA 
CCCCAGGGTG AATCACGAAG TTACGAAGTC ATGGGAAGTA TGGAAGAAAC CTTATGCAAT 
ATAGATGACA GAGATGGAAA TCGCAATGTC CATTTAGAAT TTACAGAAAG AGAGAGTAGG 
AAGGATGGAG AGGATGAATT TGTCAAAGAA ATGAGAGAGG AAAGAAAATT TCAGAAATTG 
AAGAATAAAG AGGAGGTTTT AAAAGCCTCC AGAGAAGAAA AAGTGTTGAT GGATGAAGGA 
GCAGTACTTA CCCTGGTAGC CGACCTTTCA TCAGCAACAC TGGATATTAG TAAGCAATGG 
AGTAATGTCT TCAACATTCT GAGAGAAAAT GATTTTGAAC CTAAATTTCT GTGTGAAGTT 
AAATTAGCAT TTAAATGTGA TGGTGAAATA AAGACATTTT CAGATCTGCA AAGCCTTAGA 
AAATTTGCCA GCCAAAAATC TTCTGTGAAA GAATTACTGA AAGATGTACT CCCACAAAAG 
GAAGAAATAA ATCAAGGAGG AAGAAAATAT GGAATTCAAG AAAAAAGGGA TAAAACCCTA 
ATAGACTCAA AGCATAGAGC TGGAGAAATA ACCAGTGATG GCTTGAGCTT CCTATTTCTT 
AAAGAAGTAA AAGTTGCTAA GCCAGAGGAG ATGAAAAACT TAGAGACTCA AGAGGAAGAG 
TTTTCCGAGC TAGAGGAGCT GGATGAAGAG GCCTCAGGGA TGGAGGATGA TGAAGATACC 
TCAGGGCTGG AGGAGGAGGA GGAAGAGCCC TCAGGGCTGG AGGAGGAAGA AGAAGAAGAG 
GCTTCAGGGT TGGAGGAGGA TGAGGCCTCA GGGCTAGAGG AGGAAGAGGA ACAGACTTCA 
GAACAGGACT CAACCTTTCA GGGTCATACT TTGGTAGATG CAAAGCATGA AGTTGAGATA 
ACCAGTGATG GCATGGAAAC TACTTTCATT GACTCTGTAG AGGATTCTGA ATCAGAGGAG 
GAAGAAGAAG GAAAGAGCTC TGAAACAGGA AAGGTAAAGA CTACCTCCCT GACTGAGAAA 
AAAGCCTCAC GTAGACAAAA AGAAATTCCC TTTAGTTATT TGGTTGGGGA CTCTGGGAAG 
AAAAAGTTGG TGAAACACCA GGTGGTGCAC AAAACCCAGG AGGAAGAGGA AACAGCTGTG 
CCCACAAGTC AAGGAACTGG CACACCCTGT CTGACCTTAT GTTTGGCCTC TCCCTCAAAG 
TCACTAGAGA TGAGTCATGA TGAGCATAAA AAGCATTCAC ATACAAATTT GAGTATTTCA 
ACAGGAGTCA CCAAACTTAA GAAAACAGAA GAAAAGAAAC ACAGAACTCT GCACACAGAA 
GAACTAACAT CCAAAGAAGC AGACTTAACA GAGGAAACAG AAGAAAACTT GAGAAGTAGT 
GTGATTAATA GCATCAGAGA GATAAAAGAG GAGATTGGAA ATTTGAAAAG TTCCCATTCA 
GGTGTCTTGG AAATTGAAAA TTCAGTAGAT GATCTGAGTA GCAGAATGGA CATACTTGAA 
GAAAGAATAG ACAGTCTAGA AGATCAAATT GAAGAATTCT CTAAGGATAC AATGCAAATG 
ACCAAACAGA TAATTAGTAA AGAAAGGCAA AGAGATATAG AGGAGAGATC TAGAAGTTGC 
AACATTCGTT TGATAGGAAT TCCAGAAAAG GAGAGTTATG AGAATAGGGC AGAGGACATA 
ATTAAAGAAA TAATTGATGA AAACTTTGCA GAACTAAAGA AAGGTTCAAG TCTTGAGATT 
GTCAGTGCTT GTCGAGTACC TAGTAAAATT GATGAAAAGA GACTGACTCC TAGACACATC 
TTGGTGAAAT TTTGGAATTC TAGTGATAAA GAGAAAATAA TAAGGGCTTC TAGAGAGAGA 
AGAGAAATTA CCTACCAAGG AACAAGAATC AGGTTGACAG CAGACTTATC ACTGGACACA 
CTGGATGCTA GAAGTAAATG GAGCAATGTC TTCAAAGTTC TGCTGGAAAA AGGCTTTAAT 
CCTAGAATCC TATATCCAGC CAAAATGGCA TTTGATTTTA GGGGTAAAAC AAAGGTATTT 
CTTAGTATTG AAGAATTTAG AGATTATGTT TTGCATATGC CCACCTTGAG AGAATTACTG 
GGGAATAATA TACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001158307.1
CDS	436..3033
Translation	MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEFRDYVLHMPTLRELLGNNIP

Target ORF information:

RefSeq Version	NM_001164835.1
Organism	Homo sapiens(human)
Definition	Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164835.1

ORF Insert Sequence:

ATGTCTGATG TATCTACTAG TGTACAATCA AAATTTGCTA GACTTGCAAA GAAAAAGGAA 
AATATCACCT ATATGAAAAG AGAGCAGTTA ACAGAAACTG ATAAGGACAT AGCTCCGGTA 
TTAGATTTAA AATGCAAGGA CGTATCAGCA ATTATGAATA AGTTTAAGGT CTTAATGGAA 
ATTCAAGACC TGATGTTTGA GGAGATGAGG GAAACTCTTA AAAATGACCT AAAAGCAGTT 
TTAGGGGGAA AAGCTACAAT ACCTGAGGTA AAGAATTCAG AGAACTCCAG TAGTAGGACA 
GAGTTTCAGC AAATAATCAA TTTAGCATTA CAAAAAACAG GGATGGTAGG GAAAATAGAA 
GGAGAAAACT CTAAAATAGG TGATGATAAT GAAAATTTAA CCTTTAAATT AGAAGTAAAT 
GAGCTGAGTG GTAAATTAGA CAACACTAAC GAATACAATA GTAATGATGG TAAGAAATTA 
CCCCAGGGTG AATCACGAAG TTACGAAGTC ATGGGAAGTA TGGAAGAAAC CTTATGCAAT 
ATAGATGACA GAGATGGAAA TCGCAATGTC CATTTAGAAT TTACAGAAAG AGAGAGTAGG 
AAGGATGGAG AGGATGAATT TGTCAAAGAA ATGAGAGAGG AAAGAAAATT TCAGAAATTG 
AAGAATAAAG AGGAGGTTTT AAAAGCCTCC AGAGAAGAAA AAGTGTTGAT GGATGAAGGA 
GCAGTACTTA CCCTGGTAGC CGACCTTTCA TCAGCAACAC TGGATATTAG TAAGCAATGG 
AGTAATGTCT TCAACATTCT GAGAGAAAAT GATTTTGAAC CTAAATTTCT GTGTGAAGTT 
AAATTAGCAT TTAAATGTGA TGGTGAAATA AAGACATTTT CAGATCTGCA AAGCCTTAGA 
AAATTTGCCA GCCAAAAATC TTCTGTGAAA GAATTACTGA AAGATGTACT CCCACAAAAG 
GAAGAAATAA ATCAAGGAGG AAGAAAATAT GGAATTCAAG AAAAAAGGGA TAAAACCCTA 
ATAGACTCAA AGCATAGAGC TGGAGAAATA ACCAGTGATG GCTTGAGCTT CCTATTTCTT 
AAAGAAGTAA AAGTTGCTAA GCCAGAGGAG ATGAAAAACT TAGAGACTCA AGAGGAAGAG 
TTTTCCGAGC TAGAGGAGCT GGATGAAGAG GCCTCAGGGA TGGAGGATGA TGAAGATACC 
TCAGGGCTGG AGGAGGAGGA GGAAGAGCCC TCAGGGCTGG AGGAGGAAGA AGAAGAAGAG 
GCTTCAGGGT TGGAGGAGGA TGAGGCCTCA GGGCTAGAGG AGGAAGAGGA ACAGACTTCA 
GAACAGGACT CAACCTTTCA GGGTCATACT TTGGTAGATG CAAAGCATGA AGTTGAGATA 
ACCAGTGATG GCATGGAAAC TACTTTCATT GACTCTGTAG AGGATTCTGA ATCAGAGGAG 
GAAGAAGAAG GAAAGAGCTC TGAAACAGGA AAGGTAAAGA CTACCTCCCT GACTGAGAAA 
AAAGCCTCAC GTAGACAAAA AGAAATTCCC TTTAGTTATT TGGTTGGGGA CTCTGGGAAG 
AAAAAGTTGG TGAAACACCA GGTGGTGCAC AAAACCCAGG AGGAAGAGGA AACAGCTGTG 
CCCACAAGTC AAGGAACTGG CACACCCTGT CTGACCTTAT GTTTGGCCTC TCCCTCAAAG 
TCACTAGAGA TGAGTCATGA TGAGCATAAA AAGCATTCAC ATACAAATTT GAGTATTTCA 
ACAGGAGTCA CCAAACTTAA GAAAACAGAA GAAAAGAAAC ACAGAACTCT GCACACAGAA 
GAACTAACAT CCAAAGAAGC AGACTTAACA GAGGAAACAG AAGAAAACTT GAGAAGTAGT 
GTGATTAATA GCATCAGAGA GATAAAAGAG GAGATTGGAA ATTTGAAAAG TTCCCATTCA 
GGTGTCTTGG AAATTGAAAA TTCAGTAGAT GATCTGAGTA GCAGAATGGA CATACTTGAA 
GAAAGAATAG ACAGTCTAGA AGATCAAATT GAAGAATTCT CTAAGGATAC AATGCAAATG 
ACCAAACAGA TAATTAGTAA AGAAAGGCAA AGAGATATAG AGGAGAGATC TAGAAGTTGC 
AACATTCGTT TGATAGGAAT TCCAGAAAAG GAGAGTTATG AGAATAGGGC AGAGGACATA 
ATTAAAGAAA TAATTGATGA AAACTTTGCA GAACTAAAGA AAGGTTCAAG TCTTGAGATT 
GTCAGTGCTT GTCGAGTACC TAGTAAAATT GATGAAAAGA GACTGACTCC TAGACACATC 
TTGGTGAAAT TTTGGAATTC TAGTGATAAA GAGAAAATAA TAAGGGCTTC TAGAGAGAGA 
AGAGAAATTA CCTACCAAGG AACAAGAATC AGGTTGACAG CAGACTTATC ACTGGACACA 
CTGGATGCTA GAAGTAAATG GAGCAATGTC TTCAAAGTTC TGCTGGAAAA AGGCTTTAAT 
CCTAGAATCC TATATCCAGC CAAAATGGCA TTTGATTTTA GGGGTAAAAC AAAGGTATTT 
CTTAGTATTG AAGAATTTAG AGATTATGTT TTGCATATGC CCACCTTGAG AGAATTACTG 
GGGAATAATA TACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

L1TD1 ( NM_001164835.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001158307.1 Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27206
Clone ID Related Accession (Same CDS sequence)	NM_001164835.1 , NM_001164835.2 , NM_019079.4 , NM_019079.5
Accession Version	NM_001164835.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2598bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	LINE-1 type transposase domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX167172.1, CX166941.1, DR005055.1, AK001973.1, AB211065.1, CN428323.1, BX382228.2 and BU677875.1. On May 31, 2019 this sequence version replaced NM_001164835.1. Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AK001746.1, CX781700.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGATG TATCTACTAG TGTACAATCA AAATTTGCTA GACTTGCAAA GAAAAAGGAA 
AATATCACCT ATATGAAAAG AGAGCAGTTA ACAGAAACTG ATAAGGACAT AGCTCCGGTA 
TTAGATTTAA AATGCAAGGA CGTATCAGCA ATTATGAATA AGTTTAAGGT CTTAATGGAA 
ATTCAAGACC TGATGTTTGA GGAGATGAGG GAAACTCTTA AAAATGACCT AAAAGCAGTT 
TTAGGGGGAA AAGCTACAAT ACCTGAGGTA AAGAATTCAG AGAACTCCAG TAGTAGGACA 
GAGTTTCAGC AAATAATCAA TTTAGCATTA CAAAAAACAG GGATGGTAGG GAAAATAGAA 
GGAGAAAACT CTAAAATAGG TGATGATAAT GAAAATTTAA CCTTTAAATT AGAAGTAAAT 
GAGCTGAGTG GTAAATTAGA CAACACTAAC GAATACAATA GTAATGATGG TAAGAAATTA 
CCCCAGGGTG AATCACGAAG TTACGAAGTC ATGGGAAGTA TGGAAGAAAC CTTATGCAAT 
ATAGATGACA GAGATGGAAA TCGCAATGTC CATTTAGAAT TTACAGAAAG AGAGAGTAGG 
AAGGATGGAG AGGATGAATT TGTCAAAGAA ATGAGAGAGG AAAGAAAATT TCAGAAATTG 
AAGAATAAAG AGGAGGTTTT AAAAGCCTCC AGAGAAGAAA AAGTGTTGAT GGATGAAGGA 
GCAGTACTTA CCCTGGTAGC CGACCTTTCA TCAGCAACAC TGGATATTAG TAAGCAATGG 
AGTAATGTCT TCAACATTCT GAGAGAAAAT GATTTTGAAC CTAAATTTCT GTGTGAAGTT 
AAATTAGCAT TTAAATGTGA TGGTGAAATA AAGACATTTT CAGATCTGCA AAGCCTTAGA 
AAATTTGCCA GCCAAAAATC TTCTGTGAAA GAATTACTGA AAGATGTACT CCCACAAAAG 
GAAGAAATAA ATCAAGGAGG AAGAAAATAT GGAATTCAAG AAAAAAGGGA TAAAACCCTA 
ATAGACTCAA AGCATAGAGC TGGAGAAATA ACCAGTGATG GCTTGAGCTT CCTATTTCTT 
AAAGAAGTAA AAGTTGCTAA GCCAGAGGAG ATGAAAAACT TAGAGACTCA AGAGGAAGAG 
TTTTCCGAGC TAGAGGAGCT GGATGAAGAG GCCTCAGGGA TGGAGGATGA TGAAGATACC 
TCAGGGCTGG AGGAGGAGGA GGAAGAGCCC TCAGGGCTGG AGGAGGAAGA AGAAGAAGAG 
GCTTCAGGGT TGGAGGAGGA TGAGGCCTCA GGGCTAGAGG AGGAAGAGGA ACAGACTTCA 
GAACAGGACT CAACCTTTCA GGGTCATACT TTGGTAGATG CAAAGCATGA AGTTGAGATA 
ACCAGTGATG GCATGGAAAC TACTTTCATT GACTCTGTAG AGGATTCTGA ATCAGAGGAG 
GAAGAAGAAG GAAAGAGCTC TGAAACAGGA AAGGTAAAGA CTACCTCCCT GACTGAGAAA 
AAAGCCTCAC GTAGACAAAA AGAAATTCCC TTTAGTTATT TGGTTGGGGA CTCTGGGAAG 
AAAAAGTTGG TGAAACACCA GGTGGTGCAC AAAACCCAGG AGGAAGAGGA AACAGCTGTG 
CCCACAAGTC AAGGAACTGG CACACCCTGT CTGACCTTAT GTTTGGCCTC TCCCTCAAAG 
TCACTAGAGA TGAGTCATGA TGAGCATAAA AAGCATTCAC ATACAAATTT GAGTATTTCA 
ACAGGAGTCA CCAAACTTAA GAAAACAGAA GAAAAGAAAC ACAGAACTCT GCACACAGAA 
GAACTAACAT CCAAAGAAGC AGACTTAACA GAGGAAACAG AAGAAAACTT GAGAAGTAGT 
GTGATTAATA GCATCAGAGA GATAAAAGAG GAGATTGGAA ATTTGAAAAG TTCCCATTCA 
GGTGTCTTGG AAATTGAAAA TTCAGTAGAT GATCTGAGTA GCAGAATGGA CATACTTGAA 
GAAAGAATAG ACAGTCTAGA AGATCAAATT GAAGAATTCT CTAAGGATAC AATGCAAATG 
ACCAAACAGA TAATTAGTAA AGAAAGGCAA AGAGATATAG AGGAGAGATC TAGAAGTTGC 
AACATTCGTT TGATAGGAAT TCCAGAAAAG GAGAGTTATG AGAATAGGGC AGAGGACATA 
ATTAAAGAAA TAATTGATGA AAACTTTGCA GAACTAAAGA AAGGTTCAAG TCTTGAGATT 
GTCAGTGCTT GTCGAGTACC TAGTAAAATT GATGAAAAGA GACTGACTCC TAGACACATC 
TTGGTGAAAT TTTGGAATTC TAGTGATAAA GAGAAAATAA TAAGGGCTTC TAGAGAGAGA 
AGAGAAATTA CCTACCAAGG AACAAGAATC AGGTTGACAG CAGACTTATC ACTGGACACA 
CTGGATGCTA GAAGTAAATG GAGCAATGTC TTCAAAGTTC TGCTGGAAAA AGGCTTTAAT 
CCTAGAATCC TATATCCAGC CAAAATGGCA TTTGATTTTA GGGGTAAAAC AAAGGTATTT 
CTTAGTATTG AAGAATTTAG AGATTATGTT TTGCATATGC CCACCTTGAG AGAATTACTG 
GGGAATAATA TACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001158307.1
CDS	389..2986
Translation	MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEFRDYVLHMPTLRELLGNNIP

Target ORF information:

RefSeq Version	NM_001164835.2
Organism	Homo sapiens(human)
Definition	Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164835.2

ORF Insert Sequence:

ATGTCTGATG TATCTACTAG TGTACAATCA AAATTTGCTA GACTTGCAAA GAAAAAGGAA 
AATATCACCT ATATGAAAAG AGAGCAGTTA ACAGAAACTG ATAAGGACAT AGCTCCGGTA 
TTAGATTTAA AATGCAAGGA CGTATCAGCA ATTATGAATA AGTTTAAGGT CTTAATGGAA 
ATTCAAGACC TGATGTTTGA GGAGATGAGG GAAACTCTTA AAAATGACCT AAAAGCAGTT 
TTAGGGGGAA AAGCTACAAT ACCTGAGGTA AAGAATTCAG AGAACTCCAG TAGTAGGACA 
GAGTTTCAGC AAATAATCAA TTTAGCATTA CAAAAAACAG GGATGGTAGG GAAAATAGAA 
GGAGAAAACT CTAAAATAGG TGATGATAAT GAAAATTTAA CCTTTAAATT AGAAGTAAAT 
GAGCTGAGTG GTAAATTAGA CAACACTAAC GAATACAATA GTAATGATGG TAAGAAATTA 
CCCCAGGGTG AATCACGAAG TTACGAAGTC ATGGGAAGTA TGGAAGAAAC CTTATGCAAT 
ATAGATGACA GAGATGGAAA TCGCAATGTC CATTTAGAAT TTACAGAAAG AGAGAGTAGG 
AAGGATGGAG AGGATGAATT TGTCAAAGAA ATGAGAGAGG AAAGAAAATT TCAGAAATTG 
AAGAATAAAG AGGAGGTTTT AAAAGCCTCC AGAGAAGAAA AAGTGTTGAT GGATGAAGGA 
GCAGTACTTA CCCTGGTAGC CGACCTTTCA TCAGCAACAC TGGATATTAG TAAGCAATGG 
AGTAATGTCT TCAACATTCT GAGAGAAAAT GATTTTGAAC CTAAATTTCT GTGTGAAGTT 
AAATTAGCAT TTAAATGTGA TGGTGAAATA AAGACATTTT CAGATCTGCA AAGCCTTAGA 
AAATTTGCCA GCCAAAAATC TTCTGTGAAA GAATTACTGA AAGATGTACT CCCACAAAAG 
GAAGAAATAA ATCAAGGAGG AAGAAAATAT GGAATTCAAG AAAAAAGGGA TAAAACCCTA 
ATAGACTCAA AGCATAGAGC TGGAGAAATA ACCAGTGATG GCTTGAGCTT CCTATTTCTT 
AAAGAAGTAA AAGTTGCTAA GCCAGAGGAG ATGAAAAACT TAGAGACTCA AGAGGAAGAG 
TTTTCCGAGC TAGAGGAGCT GGATGAAGAG GCCTCAGGGA TGGAGGATGA TGAAGATACC 
TCAGGGCTGG AGGAGGAGGA GGAAGAGCCC TCAGGGCTGG AGGAGGAAGA AGAAGAAGAG 
GCTTCAGGGT TGGAGGAGGA TGAGGCCTCA GGGCTAGAGG AGGAAGAGGA ACAGACTTCA 
GAACAGGACT CAACCTTTCA GGGTCATACT TTGGTAGATG CAAAGCATGA AGTTGAGATA 
ACCAGTGATG GCATGGAAAC TACTTTCATT GACTCTGTAG AGGATTCTGA ATCAGAGGAG 
GAAGAAGAAG GAAAGAGCTC TGAAACAGGA AAGGTAAAGA CTACCTCCCT GACTGAGAAA 
AAAGCCTCAC GTAGACAAAA AGAAATTCCC TTTAGTTATT TGGTTGGGGA CTCTGGGAAG 
AAAAAGTTGG TGAAACACCA GGTGGTGCAC AAAACCCAGG AGGAAGAGGA AACAGCTGTG 
CCCACAAGTC AAGGAACTGG CACACCCTGT CTGACCTTAT GTTTGGCCTC TCCCTCAAAG 
TCACTAGAGA TGAGTCATGA TGAGCATAAA AAGCATTCAC ATACAAATTT GAGTATTTCA 
ACAGGAGTCA CCAAACTTAA GAAAACAGAA GAAAAGAAAC ACAGAACTCT GCACACAGAA 
GAACTAACAT CCAAAGAAGC AGACTTAACA GAGGAAACAG AAGAAAACTT GAGAAGTAGT 
GTGATTAATA GCATCAGAGA GATAAAAGAG GAGATTGGAA ATTTGAAAAG TTCCCATTCA 
GGTGTCTTGG AAATTGAAAA TTCAGTAGAT GATCTGAGTA GCAGAATGGA CATACTTGAA 
GAAAGAATAG ACAGTCTAGA AGATCAAATT GAAGAATTCT CTAAGGATAC AATGCAAATG 
ACCAAACAGA TAATTAGTAA AGAAAGGCAA AGAGATATAG AGGAGAGATC TAGAAGTTGC 
AACATTCGTT TGATAGGAAT TCCAGAAAAG GAGAGTTATG AGAATAGGGC AGAGGACATA 
ATTAAAGAAA TAATTGATGA AAACTTTGCA GAACTAAAGA AAGGTTCAAG TCTTGAGATT 
GTCAGTGCTT GTCGAGTACC TAGTAAAATT GATGAAAAGA GACTGACTCC TAGACACATC 
TTGGTGAAAT TTTGGAATTC TAGTGATAAA GAGAAAATAA TAAGGGCTTC TAGAGAGAGA 
AGAGAAATTA CCTACCAAGG AACAAGAATC AGGTTGACAG CAGACTTATC ACTGGACACA 
CTGGATGCTA GAAGTAAATG GAGCAATGTC TTCAAAGTTC TGCTGGAAAA AGGCTTTAAT 
CCTAGAATCC TATATCCAGC CAAAATGGCA TTTGATTTTA GGGGTAAAAC AAAGGTATTT 
CTTAGTATTG AAGAATTTAG AGATTATGTT TTGCATATGC CCACCTTGAG AGAATTACTG 
GGGAATAATA TACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

L1TD1 ( NM_019079.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061952.3 Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu27206
Clone ID Related Accession (Same CDS sequence)	NM_001164835.1 , NM_001164835.2 , NM_019079.4 , NM_019079.5
Accession Version	NM_019079.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2598bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	LINE-1 type transposase domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX167172.1, DR005055.1, AK001973.1, AB211065.1, CN428323.1, BX382228.2 and BU677875.1. On Sep 19, 2009 this sequence version replaced NM_019079.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060808.1, AB211065.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTGATG TATCTACTAG TGTACAATCA AAATTTGCTA GACTTGCAAA GAAAAAGGAA 
AATATCACCT ATATGAAAAG AGAGCAGTTA ACAGAAACTG ATAAGGACAT AGCTCCGGTA 
TTAGATTTAA AATGCAAGGA CGTATCAGCA ATTATGAATA AGTTTAAGGT CTTAATGGAA 
ATTCAAGACC TGATGTTTGA GGAGATGAGG GAAACTCTTA AAAATGACCT AAAAGCAGTT 
TTAGGGGGAA AAGCTACAAT ACCTGAGGTA AAGAATTCAG AGAACTCCAG TAGTAGGACA 
GAGTTTCAGC AAATAATCAA TTTAGCATTA CAAAAAACAG GGATGGTAGG GAAAATAGAA 
GGAGAAAACT CTAAAATAGG TGATGATAAT GAAAATTTAA CCTTTAAATT AGAAGTAAAT 
GAGCTGAGTG GTAAATTAGA CAACACTAAC GAATACAATA GTAATGATGG TAAGAAATTA 
CCCCAGGGTG AATCACGAAG TTACGAAGTC ATGGGAAGTA TGGAAGAAAC CTTATGCAAT 
ATAGATGACA GAGATGGAAA TCGCAATGTC CATTTAGAAT TTACAGAAAG AGAGAGTAGG 
AAGGATGGAG AGGATGAATT TGTCAAAGAA ATGAGAGAGG AAAGAAAATT TCAGAAATTG 
AAGAATAAAG AGGAGGTTTT AAAAGCCTCC AGAGAAGAAA AAGTGTTGAT GGATGAAGGA 
GCAGTACTTA CCCTGGTAGC CGACCTTTCA TCAGCAACAC TGGATATTAG TAAGCAATGG 
AGTAATGTCT TCAACATTCT GAGAGAAAAT GATTTTGAAC CTAAATTTCT GTGTGAAGTT 
AAATTAGCAT TTAAATGTGA TGGTGAAATA AAGACATTTT CAGATCTGCA AAGCCTTAGA 
AAATTTGCCA GCCAAAAATC TTCTGTGAAA GAATTACTGA AAGATGTACT CCCACAAAAG 
GAAGAAATAA ATCAAGGAGG AAGAAAATAT GGAATTCAAG AAAAAAGGGA TAAAACCCTA 
ATAGACTCAA AGCATAGAGC TGGAGAAATA ACCAGTGATG GCTTGAGCTT CCTATTTCTT 
AAAGAAGTAA AAGTTGCTAA GCCAGAGGAG ATGAAAAACT TAGAGACTCA AGAGGAAGAG 
TTTTCCGAGC TAGAGGAGCT GGATGAAGAG GCCTCAGGGA TGGAGGATGA TGAAGATACC 
TCAGGGCTGG AGGAGGAGGA GGAAGAGCCC TCAGGGCTGG AGGAGGAAGA AGAAGAAGAG 
GCTTCAGGGT TGGAGGAGGA TGAGGCCTCA GGGCTAGAGG AGGAAGAGGA ACAGACTTCA 
GAACAGGACT CAACCTTTCA GGGTCATACT TTGGTAGATG CAAAGCATGA AGTTGAGATA 
ACCAGTGATG GCATGGAAAC TACTTTCATT GACTCTGTAG AGGATTCTGA ATCAGAGGAG 
GAAGAAGAAG GAAAGAGCTC TGAAACAGGA AAGGTAAAGA CTACCTCCCT GACTGAGAAA 
AAAGCCTCAC GTAGACAAAA AGAAATTCCC TTTAGTTATT TGGTTGGGGA CTCTGGGAAG 
AAAAAGTTGG TGAAACACCA GGTGGTGCAC AAAACCCAGG AGGAAGAGGA AACAGCTGTG 
CCCACAAGTC AAGGAACTGG CACACCCTGT CTGACCTTAT GTTTGGCCTC TCCCTCAAAG 
TCACTAGAGA TGAGTCATGA TGAGCATAAA AAGCATTCAC ATACAAATTT GAGTATTTCA 
ACAGGAGTCA CCAAACTTAA GAAAACAGAA GAAAAGAAAC ACAGAACTCT GCACACAGAA 
GAACTAACAT CCAAAGAAGC AGACTTAACA GAGGAAACAG AAGAAAACTT GAGAAGTAGT 
GTGATTAATA GCATCAGAGA GATAAAAGAG GAGATTGGAA ATTTGAAAAG TTCCCATTCA 
GGTGTCTTGG AAATTGAAAA TTCAGTAGAT GATCTGAGTA GCAGAATGGA CATACTTGAA 
GAAAGAATAG ACAGTCTAGA AGATCAAATT GAAGAATTCT CTAAGGATAC AATGCAAATG 
ACCAAACAGA TAATTAGTAA AGAAAGGCAA AGAGATATAG AGGAGAGATC TAGAAGTTGC 
AACATTCGTT TGATAGGAAT TCCAGAAAAG GAGAGTTATG AGAATAGGGC AGAGGACATA 
ATTAAAGAAA TAATTGATGA AAACTTTGCA GAACTAAAGA AAGGTTCAAG TCTTGAGATT 
GTCAGTGCTT GTCGAGTACC TAGTAAAATT GATGAAAAGA GACTGACTCC TAGACACATC 
TTGGTGAAAT TTTGGAATTC TAGTGATAAA GAGAAAATAA TAAGGGCTTC TAGAGAGAGA 
AGAGAAATTA CCTACCAAGG AACAAGAATC AGGTTGACAG CAGACTTATC ACTGGACACA 
CTGGATGCTA GAAGTAAATG GAGCAATGTC TTCAAAGTTC TGCTGGAAAA AGGCTTTAAT 
CCTAGAATCC TATATCCAGC CAAAATGGCA TTTGATTTTA GGGGTAAAAC AAAGGTATTT 
CTTAGTATTG AAGAATTTAG AGATTATGTT TTGCATATGC CCACCTTGAG AGAATTACTG 
GGGAATAATA TACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061952.3
CDS	325..2922
Translation	MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEFRDYVLHMPTLRELLGNNIP

Target ORF information:

RefSeq Version	NM_019079.4
Organism	Homo sapiens(human)
Definition	Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019079.4

ORF Insert Sequence:

ATGTCTGATG TATCTACTAG TGTACAATCA AAATTTGCTA GACTTGCAAA GAAAAAGGAA 
AATATCACCT ATATGAAAAG AGAGCAGTTA ACAGAAACTG ATAAGGACAT AGCTCCGGTA 
TTAGATTTAA AATGCAAGGA CGTATCAGCA ATTATGAATA AGTTTAAGGT CTTAATGGAA 
ATTCAAGACC TGATGTTTGA GGAGATGAGG GAAACTCTTA AAAATGACCT AAAAGCAGTT 
TTAGGGGGAA AAGCTACAAT ACCTGAGGTA AAGAATTCAG AGAACTCCAG TAGTAGGACA 
GAGTTTCAGC AAATAATCAA TTTAGCATTA CAAAAAACAG GGATGGTAGG GAAAATAGAA 
GGAGAAAACT CTAAAATAGG TGATGATAAT GAAAATTTAA CCTTTAAATT AGAAGTAAAT 
GAGCTGAGTG GTAAATTAGA CAACACTAAC GAATACAATA GTAATGATGG TAAGAAATTA 
CCCCAGGGTG AATCACGAAG TTACGAAGTC ATGGGAAGTA TGGAAGAAAC CTTATGCAAT 
ATAGATGACA GAGATGGAAA TCGCAATGTC CATTTAGAAT TTACAGAAAG AGAGAGTAGG 
AAGGATGGAG AGGATGAATT TGTCAAAGAA ATGAGAGAGG AAAGAAAATT TCAGAAATTG 
AAGAATAAAG AGGAGGTTTT AAAAGCCTCC AGAGAAGAAA AAGTGTTGAT GGATGAAGGA 
GCAGTACTTA CCCTGGTAGC CGACCTTTCA TCAGCAACAC TGGATATTAG TAAGCAATGG 
AGTAATGTCT TCAACATTCT GAGAGAAAAT GATTTTGAAC CTAAATTTCT GTGTGAAGTT 
AAATTAGCAT TTAAATGTGA TGGTGAAATA AAGACATTTT CAGATCTGCA AAGCCTTAGA 
AAATTTGCCA GCCAAAAATC TTCTGTGAAA GAATTACTGA AAGATGTACT CCCACAAAAG 
GAAGAAATAA ATCAAGGAGG AAGAAAATAT GGAATTCAAG AAAAAAGGGA TAAAACCCTA 
ATAGACTCAA AGCATAGAGC TGGAGAAATA ACCAGTGATG GCTTGAGCTT CCTATTTCTT 
AAAGAAGTAA AAGTTGCTAA GCCAGAGGAG ATGAAAAACT TAGAGACTCA AGAGGAAGAG 
TTTTCCGAGC TAGAGGAGCT GGATGAAGAG GCCTCAGGGA TGGAGGATGA TGAAGATACC 
TCAGGGCTGG AGGAGGAGGA GGAAGAGCCC TCAGGGCTGG AGGAGGAAGA AGAAGAAGAG 
GCTTCAGGGT TGGAGGAGGA TGAGGCCTCA GGGCTAGAGG AGGAAGAGGA ACAGACTTCA 
GAACAGGACT CAACCTTTCA GGGTCATACT TTGGTAGATG CAAAGCATGA AGTTGAGATA 
ACCAGTGATG GCATGGAAAC TACTTTCATT GACTCTGTAG AGGATTCTGA ATCAGAGGAG 
GAAGAAGAAG GAAAGAGCTC TGAAACAGGA AAGGTAAAGA CTACCTCCCT GACTGAGAAA 
AAAGCCTCAC GTAGACAAAA AGAAATTCCC TTTAGTTATT TGGTTGGGGA CTCTGGGAAG 
AAAAAGTTGG TGAAACACCA GGTGGTGCAC AAAACCCAGG AGGAAGAGGA AACAGCTGTG 
CCCACAAGTC AAGGAACTGG CACACCCTGT CTGACCTTAT GTTTGGCCTC TCCCTCAAAG 
TCACTAGAGA TGAGTCATGA TGAGCATAAA AAGCATTCAC ATACAAATTT GAGTATTTCA 
ACAGGAGTCA CCAAACTTAA GAAAACAGAA GAAAAGAAAC ACAGAACTCT GCACACAGAA 
GAACTAACAT CCAAAGAAGC AGACTTAACA GAGGAAACAG AAGAAAACTT GAGAAGTAGT 
GTGATTAATA GCATCAGAGA GATAAAAGAG GAGATTGGAA ATTTGAAAAG TTCCCATTCA 
GGTGTCTTGG AAATTGAAAA TTCAGTAGAT GATCTGAGTA GCAGAATGGA CATACTTGAA 
GAAAGAATAG ACAGTCTAGA AGATCAAATT GAAGAATTCT CTAAGGATAC AATGCAAATG 
ACCAAACAGA TAATTAGTAA AGAAAGGCAA AGAGATATAG AGGAGAGATC TAGAAGTTGC 
AACATTCGTT TGATAGGAAT TCCAGAAAAG GAGAGTTATG AGAATAGGGC AGAGGACATA 
ATTAAAGAAA TAATTGATGA AAACTTTGCA GAACTAAAGA AAGGTTCAAG TCTTGAGATT 
GTCAGTGCTT GTCGAGTACC TAGTAAAATT GATGAAAAGA GACTGACTCC TAGACACATC 
TTGGTGAAAT TTTGGAATTC TAGTGATAAA GAGAAAATAA TAAGGGCTTC TAGAGAGAGA 
AGAGAAATTA CCTACCAAGG AACAAGAATC AGGTTGACAG CAGACTTATC ACTGGACACA 
CTGGATGCTA GAAGTAAATG GAGCAATGTC TTCAAAGTTC TGCTGGAAAA AGGCTTTAAT 
CCTAGAATCC TATATCCAGC CAAAATGGCA TTTGATTTTA GGGGTAAAAC AAAGGTATTT 
CTTAGTATTG AAGAATTTAG AGATTATGTT TTGCATATGC CCACCTTGAG AGAATTACTG 
GGGAATAATA TACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

L1TD1 ( NM_019079.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061952.3 Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu27206
Clone ID Related Accession (Same CDS sequence)	NM_001164835.1 , NM_001164835.2 , NM_019079.4 , NM_019079.5
Accession Version	NM_019079.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2598bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	LINE-1 type transposase domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX167172.1, DR005055.1, AK001973.1, AB211065.1, CN428323.1, BX382228.2 and BU677875.1. On Nov 23, 2018 this sequence version replaced NM_019079.4. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC060808.1, AB211065.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000498273.2/ ENSP00000419901.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCTGATG TATCTACTAG TGTACAATCA AAATTTGCTA GACTTGCAAA GAAAAAGGAA 
AATATCACCT ATATGAAAAG AGAGCAGTTA ACAGAAACTG ATAAGGACAT AGCTCCGGTA 
TTAGATTTAA AATGCAAGGA CGTATCAGCA ATTATGAATA AGTTTAAGGT CTTAATGGAA 
ATTCAAGACC TGATGTTTGA GGAGATGAGG GAAACTCTTA AAAATGACCT AAAAGCAGTT 
TTAGGGGGAA AAGCTACAAT ACCTGAGGTA AAGAATTCAG AGAACTCCAG TAGTAGGACA 
GAGTTTCAGC AAATAATCAA TTTAGCATTA CAAAAAACAG GGATGGTAGG GAAAATAGAA 
GGAGAAAACT CTAAAATAGG TGATGATAAT GAAAATTTAA CCTTTAAATT AGAAGTAAAT 
GAGCTGAGTG GTAAATTAGA CAACACTAAC GAATACAATA GTAATGATGG TAAGAAATTA 
CCCCAGGGTG AATCACGAAG TTACGAAGTC ATGGGAAGTA TGGAAGAAAC CTTATGCAAT 
ATAGATGACA GAGATGGAAA TCGCAATGTC CATTTAGAAT TTACAGAAAG AGAGAGTAGG 
AAGGATGGAG AGGATGAATT TGTCAAAGAA ATGAGAGAGG AAAGAAAATT TCAGAAATTG 
AAGAATAAAG AGGAGGTTTT AAAAGCCTCC AGAGAAGAAA AAGTGTTGAT GGATGAAGGA 
GCAGTACTTA CCCTGGTAGC CGACCTTTCA TCAGCAACAC TGGATATTAG TAAGCAATGG 
AGTAATGTCT TCAACATTCT GAGAGAAAAT GATTTTGAAC CTAAATTTCT GTGTGAAGTT 
AAATTAGCAT TTAAATGTGA TGGTGAAATA AAGACATTTT CAGATCTGCA AAGCCTTAGA 
AAATTTGCCA GCCAAAAATC TTCTGTGAAA GAATTACTGA AAGATGTACT CCCACAAAAG 
GAAGAAATAA ATCAAGGAGG AAGAAAATAT GGAATTCAAG AAAAAAGGGA TAAAACCCTA 
ATAGACTCAA AGCATAGAGC TGGAGAAATA ACCAGTGATG GCTTGAGCTT CCTATTTCTT 
AAAGAAGTAA AAGTTGCTAA GCCAGAGGAG ATGAAAAACT TAGAGACTCA AGAGGAAGAG 
TTTTCCGAGC TAGAGGAGCT GGATGAAGAG GCCTCAGGGA TGGAGGATGA TGAAGATACC 
TCAGGGCTGG AGGAGGAGGA GGAAGAGCCC TCAGGGCTGG AGGAGGAAGA AGAAGAAGAG 
GCTTCAGGGT TGGAGGAGGA TGAGGCCTCA GGGCTAGAGG AGGAAGAGGA ACAGACTTCA 
GAACAGGACT CAACCTTTCA GGGTCATACT TTGGTAGATG CAAAGCATGA AGTTGAGATA 
ACCAGTGATG GCATGGAAAC TACTTTCATT GACTCTGTAG AGGATTCTGA ATCAGAGGAG 
GAAGAAGAAG GAAAGAGCTC TGAAACAGGA AAGGTAAAGA CTACCTCCCT GACTGAGAAA 
AAAGCCTCAC GTAGACAAAA AGAAATTCCC TTTAGTTATT TGGTTGGGGA CTCTGGGAAG 
AAAAAGTTGG TGAAACACCA GGTGGTGCAC AAAACCCAGG AGGAAGAGGA AACAGCTGTG 
CCCACAAGTC AAGGAACTGG CACACCCTGT CTGACCTTAT GTTTGGCCTC TCCCTCAAAG 
TCACTAGAGA TGAGTCATGA TGAGCATAAA AAGCATTCAC ATACAAATTT GAGTATTTCA 
ACAGGAGTCA CCAAACTTAA GAAAACAGAA GAAAAGAAAC ACAGAACTCT GCACACAGAA 
GAACTAACAT CCAAAGAAGC AGACTTAACA GAGGAAACAG AAGAAAACTT GAGAAGTAGT 
GTGATTAATA GCATCAGAGA GATAAAAGAG GAGATTGGAA ATTTGAAAAG TTCCCATTCA 
GGTGTCTTGG AAATTGAAAA TTCAGTAGAT GATCTGAGTA GCAGAATGGA CATACTTGAA 
GAAAGAATAG ACAGTCTAGA AGATCAAATT GAAGAATTCT CTAAGGATAC AATGCAAATG 
ACCAAACAGA TAATTAGTAA AGAAAGGCAA AGAGATATAG AGGAGAGATC TAGAAGTTGC 
AACATTCGTT TGATAGGAAT TCCAGAAAAG GAGAGTTATG AGAATAGGGC AGAGGACATA 
ATTAAAGAAA TAATTGATGA AAACTTTGCA GAACTAAAGA AAGGTTCAAG TCTTGAGATT 
GTCAGTGCTT GTCGAGTACC TAGTAAAATT GATGAAAAGA GACTGACTCC TAGACACATC 
TTGGTGAAAT TTTGGAATTC TAGTGATAAA GAGAAAATAA TAAGGGCTTC TAGAGAGAGA 
AGAGAAATTA CCTACCAAGG AACAAGAATC AGGTTGACAG CAGACTTATC ACTGGACACA 
CTGGATGCTA GAAGTAAATG GAGCAATGTC TTCAAAGTTC TGCTGGAAAA AGGCTTTAAT 
CCTAGAATCC TATATCCAGC CAAAATGGCA TTTGATTTTA GGGGTAAAAC AAAGGTATTT 
CTTAGTATTG AAGAATTTAG AGATTATGTT TTGCATATGC CCACCTTGAG AGAATTACTG 
GGGAATAATA TACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061952.3
CDS	278..2875
Translation	MSDVSTSVQSKFARLAKKKENITYMKREQLTETDKDIAPVLDLKCKDVSAIMNKFKVLMEIQDLMFEEMRETLKNDLKAVLGGKATIPEVKNSENSSSRTEFQQIINLALQKTGMVGKIEGENSKIGDDNENLTFKLEVNELSGKLDNTNEYNSNDGKKLPQGESRSYEVMGSMEETLCNIDDRDGNRNVHLEFTERESRKDGEDEFVKEMREERKFQKLKNKEEVLKASREEKVLMDEGAVLTLVADLSSATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKDVLPQKEEINQGGRKYGIQEKRDKTLIDSKHRAGEITSDGLSFLFLKEVKVAKPEEMKNLETQEEEFSELEELDEEASGMEDDEDTSGLEEEEEEPSGLEEEEEEEASGLEEDEASGLEEEEEQTSEQDSTFQGHTLVDAKHEVEITSDGMETTFIDSVEDSESEEEEEGKSSETGKVKTTSLTEKKASRRQKEIPFSYLVGDSGKKKLVKHQVVHKTQEEEETAVPTSQGTGTPCLTLCLASPSKSLEMSHDEHKKHSHTNLSISTGVTKLKKTEEKKHRTLHTEELTSKEADLTEETEENLRSSVINSIREIKEEIGNLKSSHSGVLEIENSVDDLSSRMDILEERIDSLEDQIEEFSKDTMQMTKQIISKERQRDIEERSRSCNIRLIGIPEKESYENRAEDIIKEIIDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASRERREITYQGTRIRLTADLSLDTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEFRDYVLHMPTLRELLGNNIP

Target ORF information:

RefSeq Version	NM_019079.5
Organism	Homo sapiens(human)
Definition	Homo sapiens LINE1 type transposase domain containing 1 (L1TD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019079.5

ORF Insert Sequence:

ATGTCTGATG TATCTACTAG TGTACAATCA AAATTTGCTA GACTTGCAAA GAAAAAGGAA 
AATATCACCT ATATGAAAAG AGAGCAGTTA ACAGAAACTG ATAAGGACAT AGCTCCGGTA 
TTAGATTTAA AATGCAAGGA CGTATCAGCA ATTATGAATA AGTTTAAGGT CTTAATGGAA 
ATTCAAGACC TGATGTTTGA GGAGATGAGG GAAACTCTTA AAAATGACCT AAAAGCAGTT 
TTAGGGGGAA AAGCTACAAT ACCTGAGGTA AAGAATTCAG AGAACTCCAG TAGTAGGACA 
GAGTTTCAGC AAATAATCAA TTTAGCATTA CAAAAAACAG GGATGGTAGG GAAAATAGAA 
GGAGAAAACT CTAAAATAGG TGATGATAAT GAAAATTTAA CCTTTAAATT AGAAGTAAAT 
GAGCTGAGTG GTAAATTAGA CAACACTAAC GAATACAATA GTAATGATGG TAAGAAATTA 
CCCCAGGGTG AATCACGAAG TTACGAAGTC ATGGGAAGTA TGGAAGAAAC CTTATGCAAT 
ATAGATGACA GAGATGGAAA TCGCAATGTC CATTTAGAAT TTACAGAAAG AGAGAGTAGG 
AAGGATGGAG AGGATGAATT TGTCAAAGAA ATGAGAGAGG AAAGAAAATT TCAGAAATTG 
AAGAATAAAG AGGAGGTTTT AAAAGCCTCC AGAGAAGAAA AAGTGTTGAT GGATGAAGGA 
GCAGTACTTA CCCTGGTAGC CGACCTTTCA TCAGCAACAC TGGATATTAG TAAGCAATGG 
AGTAATGTCT TCAACATTCT GAGAGAAAAT GATTTTGAAC CTAAATTTCT GTGTGAAGTT 
AAATTAGCAT TTAAATGTGA TGGTGAAATA AAGACATTTT CAGATCTGCA AAGCCTTAGA 
AAATTTGCCA GCCAAAAATC TTCTGTGAAA GAATTACTGA AAGATGTACT CCCACAAAAG 
GAAGAAATAA ATCAAGGAGG AAGAAAATAT GGAATTCAAG AAAAAAGGGA TAAAACCCTA 
ATAGACTCAA AGCATAGAGC TGGAGAAATA ACCAGTGATG GCTTGAGCTT CCTATTTCTT 
AAAGAAGTAA AAGTTGCTAA GCCAGAGGAG ATGAAAAACT TAGAGACTCA AGAGGAAGAG 
TTTTCCGAGC TAGAGGAGCT GGATGAAGAG GCCTCAGGGA TGGAGGATGA TGAAGATACC 
TCAGGGCTGG AGGAGGAGGA GGAAGAGCCC TCAGGGCTGG AGGAGGAAGA AGAAGAAGAG 
GCTTCAGGGT TGGAGGAGGA TGAGGCCTCA GGGCTAGAGG AGGAAGAGGA ACAGACTTCA 
GAACAGGACT CAACCTTTCA GGGTCATACT TTGGTAGATG CAAAGCATGA AGTTGAGATA 
ACCAGTGATG GCATGGAAAC TACTTTCATT GACTCTGTAG AGGATTCTGA ATCAGAGGAG 
GAAGAAGAAG GAAAGAGCTC TGAAACAGGA AAGGTAAAGA CTACCTCCCT GACTGAGAAA 
AAAGCCTCAC GTAGACAAAA AGAAATTCCC TTTAGTTATT TGGTTGGGGA CTCTGGGAAG 
AAAAAGTTGG TGAAACACCA GGTGGTGCAC AAAACCCAGG AGGAAGAGGA AACAGCTGTG 
CCCACAAGTC AAGGAACTGG CACACCCTGT CTGACCTTAT GTTTGGCCTC TCCCTCAAAG 
TCACTAGAGA TGAGTCATGA TGAGCATAAA AAGCATTCAC ATACAAATTT GAGTATTTCA 
ACAGGAGTCA CCAAACTTAA GAAAACAGAA GAAAAGAAAC ACAGAACTCT GCACACAGAA 
GAACTAACAT CCAAAGAAGC AGACTTAACA GAGGAAACAG AAGAAAACTT GAGAAGTAGT 
GTGATTAATA GCATCAGAGA GATAAAAGAG GAGATTGGAA ATTTGAAAAG TTCCCATTCA 
GGTGTCTTGG AAATTGAAAA TTCAGTAGAT GATCTGAGTA GCAGAATGGA CATACTTGAA 
GAAAGAATAG ACAGTCTAGA AGATCAAATT GAAGAATTCT CTAAGGATAC AATGCAAATG 
ACCAAACAGA TAATTAGTAA AGAAAGGCAA AGAGATATAG AGGAGAGATC TAGAAGTTGC 
AACATTCGTT TGATAGGAAT TCCAGAAAAG GAGAGTTATG AGAATAGGGC AGAGGACATA 
ATTAAAGAAA TAATTGATGA AAACTTTGCA GAACTAAAGA AAGGTTCAAG TCTTGAGATT 
GTCAGTGCTT GTCGAGTACC TAGTAAAATT GATGAAAAGA GACTGACTCC TAGACACATC 
TTGGTGAAAT TTTGGAATTC TAGTGATAAA GAGAAAATAA TAAGGGCTTC TAGAGAGAGA 
AGAGAAATTA CCTACCAAGG AACAAGAATC AGGTTGACAG CAGACTTATC ACTGGACACA 
CTGGATGCTA GAAGTAAATG GAGCAATGTC TTCAAAGTTC TGCTGGAAAA AGGCTTTAAT 
CCTAGAATCC TATATCCAGC CAAAATGGCA TTTGATTTTA GGGGTAAAAC AAAGGTATTT 
CTTAGTATTG AAGAATTTAG AGATTATGTT TTGCATATGC CCACCTTGAG AGAATTACTG 
GGGAATAATA TACCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers.
Molecular cancer16(1)1(2017 01)
Altenberger C,Heller G,Ziegler B,Tomasich E,Marhold M,Topakian T,M?llauer L,Heffeter P,Lang G,End-Pf?tzenreuter A,D?me B,Arns BM,Klepetko W,Zielinski CC,Z?chbauer-M?ller S

Embryonic Stem Cell-Related Protein L1TD1 Is Required for Cell Viability, Neurosphere Formation, and Chemoresistance in Medulloblastoma.
Stem cells and development24(22)2700-8(2015 Nov)
Santos MC,Silva PB,Rodini CO,Furukawa G,Marco Antonio DS,Zanotto-Filho A,Moreira JC,Okamoto OK

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L1TD1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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