OR10C1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	OR10C1
Entrez Gene ID	442194
Full Name	olfactory receptor family 10 subfamily C member 1 (gene/pseudogene)
Synonyms	OR10C1P,OR10C2,OR6-31,hs6M1-17
General protein information	Preferred Names olfactory receptor family 10 subfamily C member 1 (gene/pseudogene) Names olfactory receptor 10C1 olfactory receptor 10C2 olfactory receptor OR6-31 olfactory receptor, family 10, subfamily C, member 1 olfactory receptor, family 10, subfamily C, member 2 seven transmembrane helix receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p22.1
Summary	Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jul 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_013941.3	NP_039229.3	olfactory receptor 10C1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	OR10C1	XP_002697445.1
Mus musculus (house mouse)	Olfr95	NP_666724.1
Pan troglodytes (chimpanzee)	LOC471942	XP_527320.1
Homo sapiens (human)	OR10C1	NP_039229.3
Rattus norvegicus (Norway rat)	Olr1744	NP_001001426.1
Canis lupus familiaris (dog)	LOC100856344	XP_003640204.1

Gene Ontology
Bibliography

Related articles in PubMed

Personal receptor repertoires: olfaction as a model.
Olender T, Waszak SM, Viavant M, Khen M, Ben-Asher E, Reyes A, Nativ N, Wysocki CJ, Ge D, Lancet D
BMC genomics13414(2012 Aug)

Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors.
Thompson EE, Haller G, Pinto JM, Sun Y, Zelano B, Jacob S, McClintock MK, Nicolae DL, Ober C
Human immunology71(1)100-3(2010 Jan)

A probabilistic classifier for olfactory receptor pseudogenes.
Menashe I, Aloni R, Lancet D
BMC bioinformatics7393(2006 Aug)

The human olfactory receptor gene family.
Malnic B, Godfrey PA, Buck LB
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)

Complex transcription and splicing of odorant receptor genes.
Volz A, Ehlers A, Younger R, Forbes S, Trowsdale J, Schnorr D, Beck S, Ziegler A
The Journal of biological chemistry278(22)19691-701(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors.

The following OR10C1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OR10C1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu55760	NM_013941.3 Latest version!	Homo sapiens olfactory receptor family 10 subfamily C member 1 (gene/pseudogene) (OR10C1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OR10C1 ( NM_013941.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_039229.3 Homo sapiens olfactory receptor family 10 subfamily C member 1 (gene/pseudogene) (OR10C1), mRNA.

Price & Availability↑

CloneID	OHu55760
Clone ID Related Accession (Same CDS sequence)	NM_013941.3
Accession Version	NM_013941.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 939bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	olfactory receptor 10C1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC136997.1. On May 11, 2011 this sequence version replaced NM_013941.2. Sequence Note: This gene is a segregating pseudogene. This RefSeq represents the protein encoded by the reference genome allele, which is predicted to be functional according to the Classifier for Olfactory Receptor Pseudogenes. CCDS Note: This olfactory receptor gene is a segregating pseudogene (PMID:22908908), where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele that is predicted to be non-functional. This CCDS is being retained because the Classifier for Olfactory Receptor Pseudogenes (CORP) predicts the reference genome allele to be functional. ##Evidence-Data-START## Transcript is intronless :: BC136996.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## polymorphic pseudogene :: PMID: 22908908 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAGTGCAA ACACCTCCAT GGTGACTGAG TTTCTTCTTC TCGGCTTCTC CCACCTGGCC 
GACCTCCAGG GCTTGCTCTT CTCTGTCTTT CTCACTATCT ACCTGCTGAC CGTGGCAGGC 
AATTTCCTCA TTGTGGTGCT GGTCTCCACT GATGCTGCCC TCCAGTCCCC TATGTACTTC 
TTCCTGCGCA CCCTCTCGGC CTTGGAGATT GGCTATACGT CTGTCACGGT CCCCCTGCTA 
CTTCACCACC TCCTTACTGG CCGGCGCCAC ATCTCTCGCT CTGGATGTGC TCTCCAGATG 
TTCTTCTTCC TCTTCTTTGG CGCCACGGAG TGCTGCCTCC TGGCAGCCAT GGCCTATGAC 
CGCTATGCAG CCATCTGTGA ACCCCTCCGC TACCCACTGC TGCTGAGCCA CCGGGTGTGT 
CTACAGCTAG CTGGGTCGGC GTGGGCCTGT GGGGTGCTGG TGGGGCTGGG CCACACCCCT 
TTCATCTTCT CTTTGCCCTT CTGCGGCCCC AATACCATCC CGCAGTTCTT CTGTGAGATC 
CAGCCTGTCC TGCAGCTGGT ATGTGGAGAC ACCTCGCTTA ATGAACTGCA GATTATCCTG 
GCAACAGCCC TCCTCATCCT CTGCCCCTTT GGCCTCATCC TGGGCTCCTA CGGGCGTATC 
CTCGTTACCA TCTTCCGGAT CCCATCTGTT GCGGGCCGCC GCAAGGCCTT CTCCACCTGC 
TCCTCCCACC TGATCATGGT CTCCCTCTTC TATGGCACCG CACTCTTTAT CTATATTCGC 
CCTAAGGCCA GCTACGATCC GGCCACTGAC CCTCTGGTGT CCCTCTTCTA TGCTGTGGTC 
ACCCCCATCC TCAACCCCAT CATCTACAGC CTGCGGAACA CAGAGGTCAA AGCTGCCCTA 
AAGAGAACCA TCCAGAAAAC GGTGCCTATG GAGATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_039229.3
CDS	78..1016
Translation	MSANTSMVTEFLLLGFSHLADLQGLLFSVFLTIYLLTVAGNFLIVVLVSTDAALQSPMYFFLRTLSALEIGYTSVTVPLLLHHLLTGRRHISRSGCALQMFFFLFFGATECCLLAAMAYDRYAAICEPLRYPLLLSHRVCLQLAGSAWACGVLVGLGHTPFIFSLPFCGPNTIPQFFCEIQPVLQLVCGDTSLNELQIILATALLILCPFGLILGSYGRILVTIFRIPSVAGRRKAFSTCSSHLIMVSLFYGTALFIYIRPKASYDPATDPLVSLFYAVVTPILNPIIYSLRNTEVKAALKRTIQKTVPMEI

Target ORF information:

RefSeq Version	NM_013941.3
Organism	Homo sapiens(human)
Definition	Homo sapiens olfactory receptor family 10 subfamily C member 1 (gene/pseudogene) (OR10C1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013941.3

ORF Insert Sequence:

ATGAGTGCAA ACACCTCCAT GGTGACTGAG TTTCTTCTTC TCGGCTTCTC CCACCTGGCC 
GACCTCCAGG GCTTGCTCTT CTCTGTCTTT CTCACTATCT ACCTGCTGAC CGTGGCAGGC 
AATTTCCTCA TTGTGGTGCT GGTCTCCACT GATGCTGCCC TCCAGTCCCC TATGTACTTC 
TTCCTGCGCA CCCTCTCGGC CTTGGAGATT GGCTATACGT CTGTCACGGT CCCCCTGCTA 
CTTCACCACC TCCTTACTGG CCGGCGCCAC ATCTCTCGCT CTGGATGTGC TCTCCAGATG 
TTCTTCTTCC TCTTCTTTGG CGCCACGGAG TGCTGCCTCC TGGCAGCCAT GGCCTATGAC 
CGCTATGCAG CCATCTGTGA ACCCCTCCGC TACCCACTGC TGCTGAGCCA CCGGGTGTGT 
CTACAGCTAG CTGGGTCGGC GTGGGCCTGT GGGGTGCTGG TGGGGCTGGG CCACACCCCT 
TTCATCTTCT CTTTGCCCTT CTGCGGCCCC AATACCATCC CGCAGTTCTT CTGTGAGATC 
CAGCCTGTCC TGCAGCTGGT ATGTGGAGAC ACCTCGCTTA ATGAACTGCA GATTATCCTG 
GCAACAGCCC TCCTCATCCT CTGCCCCTTT GGCCTCATCC TGGGCTCCTA CGGGCGTATC 
CTCGTTACCA TCTTCCGGAT CCCATCTGTT GCGGGCCGCC GCAAGGCCTT CTCCACCTGC 
TCCTCCCACC TGATCATGGT CTCCCTCTTC TATGGCACCG CACTCTTTAT CTATATTCGC 
CCTAAGGCCA GCTACGATCC GGCCACTGAC CCTCTGGTGT CCCTCTTCTA TGCTGTGGTC 
ACCCCCATCC TCAACCCCAT CATCTACAGC CTGCGGAACA CAGAGGTCAA AGCTGCCCTA 
AAGAGAACCA TCCAGAAAAC GGTGCCTATG GAGATTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Personal receptor repertoires: olfaction as a model.
BMC genomics13414(2012 Aug)
Olender T,Waszak SM,Viavant M,Khen M,Ben-Asher E,Reyes A,Nativ N,Wysocki CJ,Ge D,Lancet D

Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors.
Human immunology71(1)100-3(2010 Jan)
Thompson EE,Haller G,Pinto JM,Sun Y,Zelano B,Jacob S,McClintock MK,Nicolae DL,Ober C

A probabilistic classifier for olfactory receptor pseudogenes.
BMC bioinformatics7393(2006 Aug)
Menashe I,Aloni R,Lancet D

The human olfactory receptor gene family.
Proceedings of the National Academy of Sciences of the United States of America101(8)2584-9(2004 Feb)
Malnic B,Godfrey PA,Buck LB

Complex transcription and splicing of odorant receptor genes.
The Journal of biological chemistry278(22)19691-701(2003 May)
Volz A,Ehlers A,Younger R,Forbes S,Trowsdale J,Schnorr D,Beck S,Ziegler A

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OR10C1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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