COA6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	COA6
Entrez Gene ID	388753
Full Name	cytochrome c oxidase assembly factor 6
Synonyms	C1orf31,CEMCOX4
General protein information	Preferred Names cytochrome c oxidase assembly factor 6 Names cytochrome c oxidase assembly factor 6 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q42.2
Summary	This gene encodes a member of the cytochrome c oxidase subunit 6B family. The encoded protein associates with cytochrome c oxidase may act has an cytochrome c oxidase mitochondrial respiratory complex VI assembly factor. Mutations in this gene may be associated with fatal infantile cardiomyopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014].
Disorder MIM:	614772
Disorder Html:	Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 4, 616501 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001206641.3	NP_001193570.2	cytochrome c oxidase assembly factor 6 homolog isoform 2
NM_001301733.1	NP_001288662.1	cytochrome c oxidase assembly factor 6 homolog isoform 3
NM_001206641.2	NP_001193570.2	cytochrome c oxidase assembly factor 6 homolog isoform 2
NM_001012985.2	NP_001013003.1	cytochrome c oxidase assembly factor 6 homolog isoform 1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis.
Lorenzi I, Oeljeklaus S, Aich A, Rons?r C, Callegari S, Dudek J, Warscheid B, Dennerlein S, Rehling P
Biochimica et biophysica acta1865(2)323-333(2018 Feb)

Human mitochondrial cytochrome
Bourens M, Barrientos A
The Journal of biological chemistry292(19)7774-7783(2017 05)

COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2.
Stroud DA, Maher MJ, Lindau C, V?gtle FN, Frazier AE, Surgenor E, Mountford H, Singh AP, Bonas M, Oeljeklaus S, Warscheid B, Meisinger C, Thorburn DR, Ryan MT
Human molecular genetics24(19)5404-15(2015 Oct)

Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency.
Ghosh A, Trivedi PP, Timbalia SA, Griffin AT, Rahn JJ, Chan SS, Gohil VM
Human molecular genetics23(13)3596-606(2014 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results find that COA6 associates with COX2 and is crucial for its maturation and complex IV biogenesis. Also, COA6 interacts with the copper chaperone SCO1 which indicates that COA6 is intrinsically involved in the copper delivery process for COX2.
Title: COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2.

Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies.
Title: Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies.

COX assembly candidate, ortholog of fungal YMR244C-A
Title: Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase.

Strong candidate gene for mitochondrial disease, based on recessive mutations detected in infantile patients
Title: Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

The following COA6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COA6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu35021	NM_001206641.3 Latest version!	Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu55589	NM_001012985.2 Latest version!	Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu32241	NM_001301733.1 Latest version!	Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$69.30 $99.00
View Old Accession Versions >>
OHu35021	NM_001206641.2	Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

COA6 ( NM_001206641.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001193570.2 Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu35021
Clone ID Related Accession (Same CDS sequence)	NM_001206641.3 , NM_001206641.2
Accession Version	NM_001206641.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	cytochrome c oxidase assembly factor 6 homolog isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY169996.1, BC035925.1, BG204581.1 and AL355472.19. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_001206641.2. Transcript Variant: This variant (2) uses an alternate 5' most exon which results in the use of an alternate AUG, compared to variant 1. The resulting isoform (2) has a distinct and longer N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.123402.1, SRR1660805.77765.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTAGCTC GGAAGGGTCA AAAGAGTCCG CGGTTTCGCC GCGTGAGTTG CTTTTTGCGG 
CTGGGGAGGT CTACGCTTCT AGAGCTTGAG CCAGCGGGGC GACCCTGCAG TGGCAGGACT 
CGGCACCGCG CCCTCCACCG CCGGTTGGTG GCCTGCGTGA CAGTTTCCTC CCGTCGACAT 
CGAAAGGAAG CCGGACGTGG GCGGGCAGAG AGCTTCATCG CAGTAGGAAT GGCAGCCCCA 
TCTATGAAGG AAAGACAGGT CTGCTGGGGG GCCCGGGATG AGTACTGGAA GTGTTTAGAT 
GAGAACTTAG AGGATGCTTC TCAATGCAAG AAGTTAAGAA GCTCTTTCGA ATCAAGTTGT 
CCCCAACAGT GGATAAAATA TTTTGATAAA AGAAGAGACT ACTTAAAATT CAAAGAAAAA 
TTTGAAGCAG GACAATTTGA GCCTTCAGAA ACAACTGCAA AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001193570.2
CDS	12..479
Translation	MVARKGQKSPRFRRVSCFLRLGRSTLLELEPAGRPCSGRTRHRALHRRLVACVTVSSRRHRKEAGRGRAESFIAVGMAAPSMKERQVCWGARDEYWKCLDENLEDASQCKKLRSSFESSCPQQWIKYFDKRRDYLKFKEKFEAGQFEPSETTAKS

Target ORF information:

RefSeq Version	NM_001206641.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001206641.3

ORF Insert Sequence:

ATGGTAGCTC GGAAGGGTCA AAAGAGTCCG CGGTTTCGCC GCGTGAGTTG CTTTTTGCGG 
CTGGGGAGGT CTACGCTTCT AGAGCTTGAG CCAGCGGGGC GACCCTGCAG TGGCAGGACT 
CGGCACCGCG CCCTCCACCG CCGGTTGGTG GCCTGCGTGA CAGTTTCCTC CCGTCGACAT 
CGAAAGGAAG CCGGACGTGG GCGGGCAGAG AGCTTCATCG CAGTAGGAAT GGCAGCCCCA 
TCTATGAAGG AAAGACAGGT CTGCTGGGGG GCCCGGGATG AGTACTGGAA GTGTTTAGAT 
GAGAACTTAG AGGATGCTTC TCAATGCAAG AAGTTAAGAA GCTCTTTCGA ATCAAGTTGT 
CCCCAACAGT GGATAAAATA TTTTGATAAA AGAAGAGACT ACTTAAAATT CAAAGAAAAA 
TTTGAAGCAG GACAATTTGA GCCTTCAGAA ACAACTGCAA AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COA6 ( NM_001206641.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001193570.2 Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu35021
Clone ID Related Accession (Same CDS sequence)	NM_001206641.3 , NM_001206641.2
Accession Version	NM_001206641.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-23
Organism	Homo sapiens(human)
Product	cytochrome c oxidase assembly factor 6 homolog isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY169996.1, BC035925.1 and BG204581.1. This sequence is a reference standard in the RefSeqGene project. On or before Sep 11, 2014 this sequence version replaced XM_005273123.2, NM_001206641.1. Transcript Variant: This variant (2) uses an alternate 5' most exon which results in the use of an alternate AUG, compared to variant 1. The resulting isoform (2) has a distinct and longer N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.430544.1, SRR1163655.3141.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTAGCTC GGAAGGGTCA AAAGAGTCCG CGGTTTCGCC GCGTGAGTTG CTTTTTGCGG 
CTGGGGAGGT CTACGCTTCT AGAGCTTGAG CCAGCGGGGC GACCCTGCAG TGGCAGGACT 
CGGCACCGCG CCCTCCACCG CCGGTTGGTG GCCTGCGTGA CAGTTTCCTC CCGTCGACAT 
CGAAAGGAAG CCGGACGTGG GCGGGCAGAG AGCTTCATCG CAGTAGGAAT GGCAGCCCCA 
TCTATGAAGG AAAGACAGGT CTGCTGGGGG GCCCGGGATG AGTACTGGAA GTGTTTAGAT 
GAGAACTTAG AGGATGCTTC TCAATGCAAG AAGTTAAGAA GCTCTTTCGA ATCAAGTTGT 
CCCCAACAGT GGATAAAATA TTTTGATAAA AGAAGAGACT ACTTAAAATT CAAAGAAAAA 
TTTGAAGCAG GACAATTTGA GCCTTCAGAA ACAACTGCAA AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001193570.2
CDS	31..498
Translation	MVARKGQKSPRFRRVSCFLRLGRSTLLELEPAGRPCSGRTRHRALHRRLVACVTVSSRRHRKEAGRGRAESFIAVGMAAPSMKERQVCWGARDEYWKCLDENLEDASQCKKLRSSFESSCPQQWIKYFDKRRDYLKFKEKFEAGQFEPSETTAKS

Target ORF information:

RefSeq Version	NM_001206641.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001206641.2

ORF Insert Sequence:

ATGGTAGCTC GGAAGGGTCA AAAGAGTCCG CGGTTTCGCC GCGTGAGTTG CTTTTTGCGG 
CTGGGGAGGT CTACGCTTCT AGAGCTTGAG CCAGCGGGGC GACCCTGCAG TGGCAGGACT 
CGGCACCGCG CCCTCCACCG CCGGTTGGTG GCCTGCGTGA CAGTTTCCTC CCGTCGACAT 
CGAAAGGAAG CCGGACGTGG GCGGGCAGAG AGCTTCATCG CAGTAGGAAT GGCAGCCCCA 
TCTATGAAGG AAAGACAGGT CTGCTGGGGG GCCCGGGATG AGTACTGGAA GTGTTTAGAT 
GAGAACTTAG AGGATGCTTC TCAATGCAAG AAGTTAAGAA GCTCTTTCGA ATCAAGTTGT 
CCCCAACAGT GGATAAAATA TTTTGATAAA AGAAGAGACT ACTTAAAATT CAAAGAAAAA 
TTTGAAGCAG GACAATTTGA GCCTTCAGAA ACAACTGCAA AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COA6 ( NM_001012985.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001013003.1 Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55589
Clone ID Related Accession (Same CDS sequence)	NM_001012985.2
Accession Version	NM_001012985.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	cytochrome c oxidase assembly factor 6 homolog isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC116455.1 and BG195363.1. On Apr 30, 2011 this sequence version replaced NM_001012985.1. Transcript Variant: This variant (1) encodes isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC116455.1, SRR1163658.286733.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGCCCGG GAGGTCCCTT ACTGTCCCCG AGCCGCGGGT TCCTCTTGTG CAAAACGGGG 
TGGCACTCCA ATCGCCTGCT TGGTGATTGT GGCCCCCACA CACCTGTTTC TACAGCGCTT 
AGCTTCATCG CAGTAGGAAT GGCAGCCCCA TCTATGAAGG AAAGACAGGT CTGCTGGGGG 
GCCCGGGATG AGTACTGGAA GTGTTTAGAT GAGAACTTAG AGGATGCTTC TCAATGCAAG 
AAGTTAAGAA GCTCTTTCGA ATCAAGTTGT CCCCAACAGT GGATAAAATA TTTTGATAAA 
AGAAGAGACT ACTTAAAATT CAAAGAAAAA TTTGAAGCAG GACAATTTGA GCCTTCAGAA 
ACAACTGCAA AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013003.1
CDS	37..414
Translation	MGPGGPLLSPSRGFLLCKTGWHSNRLLGDCGPHTPVSTALSFIAVGMAAPSMKERQVCWGARDEYWKCLDENLEDASQCKKLRSSFESSCPQQWIKYFDKRRDYLKFKEKFEAGQFEPSETTAKS

Target ORF information:

RefSeq Version	NM_001012985.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012985.2

ORF Insert Sequence:

ATGGGCCCGG GAGGTCCCTT ACTGTCCCCG AGCCGCGGGT TCCTCTTGTG CAAAACGGGG 
TGGCACTCCA ATCGCCTGCT TGGTGATTGT GGCCCCCACA CACCTGTTTC TACAGCGCTT 
AGCTTCATCG CAGTAGGAAT GGCAGCCCCA TCTATGAAGG AAAGACAGGT CTGCTGGGGG 
GCCCGGGATG AGTACTGGAA GTGTTTAGAT GAGAACTTAG AGGATGCTTC TCAATGCAAG 
AAGTTAAGAA GCTCTTTCGA ATCAAGTTGT CCCCAACAGT GGATAAAATA TTTTGATAAA 
AGAAGAGACT ACTTAAAATT CAAAGAAAAA TTTGAAGCAG GACAATTTGA GCCTTCAGAA 
ACAACTGCAA AATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

COA6 ( NM_001301733.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001288662.1 Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu32241
Clone ID Related Accession (Same CDS sequence)	NM_001301733.1
Accession Version	NM_001301733.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 240bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	cytochrome c oxidase assembly factor 6 homolog isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC064905.1 and BG204581.1. Transcript Variant: This variant (3) uses an alternate 5' structure which results in the use of a downstream AUG compared to variant 1. The encoded isoform (3) has a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC064905.1, ERR279862.5549.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCAGCCC CATCTATGAA GGAAAGACAG GTCTGCTGGG GGGCCCGGGA TGAGTACTGG 
AAGTGTTTAG ATGAGAACTT AGAGGATGCT TCTCAATGCA AGAAGTTAAG AAGCTCTTTC 
GAATCAAGTT GTCCCCAACA GTGGATAAAA TATTTTGATA AAAGAAGAGA CTACTTAAAA 
TTCAAAGAAA AATTTGAAGC AGGACAATTT GAGCCTTCAG AAACAACTGC AAAATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001288662.1
CDS	546..785
Translation	MAAPSMKERQVCWGARDEYWKCLDENLEDASQCKKLRSSFESSCPQQWIKYFDKRRDYLKFKEKFEAGQFEPSETTAKS

Target ORF information:

RefSeq Version	NM_001301733.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cytochrome c oxidase assembly factor 6 (COA6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001301733.1

ORF Insert Sequence:

ATGGCAGCCC CATCTATGAA GGAAAGACAG GTCTGCTGGG GGGCCCGGGA TGAGTACTGG 
AAGTGTTTAG ATGAGAACTT AGAGGATGCT TCTCAATGCA AGAAGTTAAG AAGCTCTTTC 
GAATCAAGTT GTCCCCAACA GTGGATAAAA TATTTTGATA AAAGAAGAGA CTACTTAAAA 
TTCAAAGAAA AATTTGAAGC AGGACAATTT GAGCCTTCAG AAACAACTGC AAAATCCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis.
Biochimica et biophysica acta1865(2)323-333(2018 Feb)
Lorenzi I,Oeljeklaus S,Aich A,Rons?r C,Callegari S,Dudek J,Warscheid B,Dennerlein S,Rehling P

Human mitochondrial cytochrome
The Journal of biological chemistry292(19)7774-7783(2017 05)
Bourens M,Barrientos A

COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2.
Human molecular genetics24(19)5404-15(2015 Oct)
Stroud DA,Maher MJ,Lindau C,V?gtle FN,Frazier AE,Surgenor E,Mountford H,Singh AP,Bonas M,Oeljeklaus S,Warscheid B,Meisinger C,Thorburn DR,Ryan MT

Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency.
Human molecular genetics23(13)3596-606(2014 Jul)
Ghosh A,Trivedi PP,Timbalia SA,Griffin AT,Rahn JJ,Chan SS,Gohil VM

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COA6 cDNA ORF clone, Homo sapiens(human)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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