Gene Symbol | IL36A |
Entrez Gene ID | 27179 |
Full Name | interleukin 36 alpha |
Synonyms | FIL1,FIL1(EPSILON),FIL1E,IL-1F6,IL1(EPSILON),IL1F6 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015]. |
Disorder MIM: |