gRNAs
The following KLB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KLB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu24417 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_175737.3 , NM_175737.4 | |
| Accession Version | NM_175737.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3135bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-01 | |
| Organism | Homo sapiens(human) | |
| Product | beta-klotho | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB079373.1, AK302436.1, BJ993426.1 and AC021148.8. On Sep 5, 2008 this sequence version replaced NM_175737.2. Sequence Note: The 3' UTR of the RefSeq transcript was derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record was based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB079373.1, BC104871.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGAAGCCAG GCTGTGCGGC AGGATCTCCA GGGAATGAAT GGATTTTCTT CAGCACTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_783864.1 |
| CDS | 98..3232 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_175737.3 |
1 | ATGAAGCCAG GCTGTGCGGC AGGATCTCCA GGGAATGAAT GGATTTTCTT CAGCACTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu24417 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_175737.3 , NM_175737.4 | |
| Accession Version | NM_175737.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3135bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-02 | |
| Organism | Homo sapiens(human) | |
| Product | beta-klotho | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB079373.1, AK302436.1, BJ993426.1 and AC021148.8. On Nov 22, 2018 this sequence version replaced NM_175737.3. Sequence Note: The 3' UTR of the RefSeq transcript was derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record was based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC104871.1, AB079373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142586, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000257408.5/ ENSP00000257408.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGAAGCCAG GCTGTGCGGC AGGATCTCCA GGGAATGAAT GGATTTTCTT CAGCACTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_783864.1 |
| CDS | 21..3155 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_175737.4 |
1 | ATGAAGCCAG GCTGTGCGGC AGGATCTCCA GGGAATGAAT GGATTTTCTT CAGCACTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Structures of ?-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. |
