The following MTRNR2L4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MTRNR2L4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu01979 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001190476.2 , NM_001190476.1 | |
| Accession Version | NM_001190476.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 87bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-24 | |
| Organism | Homo sapiens(human) | |
| Product | humanin-like 4 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025283.6. On May 20, 2019 this sequence version replaced NM_001190476.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. CCDS Note: This gene represents one of several nuclear copies of the mitochondrial MT-RNR2 gene, which is transcribed as part of the 16S subunit of rRNA and can encode the neuroprotective peptide humanin. RT-PCR evidence in PMID:19477263 suggests that this nuclear gene copy is transcribed. The humanin protein has been detected in vivo (e.g., PMIDs 12009529, 19623253 and 20542501) but it is unclear if this protein is translated from mitochondrial or nuclear gene transcripts. Thus, there is some uncertainty about protein production from this nuclear gene copy. This CCDS is represented because protein production cannot be definitively ruled out for this gene. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000399974.5/ ENSP00000382856.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## | |
1 | ATGGCCACAC AAGGGTTCAG CTGTCTCTTA CTTTCAGTCA GTGAAATTGA CCTATCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001177405.1 |
| CDS | 767..853 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001190476.2 |
1 | ATGGCCACAC AAGGGTTCAG CTGTCTCTTA CTTTCAGTCA GTGAAATTGA CCTATCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu01979 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001190476.2 , NM_001190476.1 | |
| Accession Version | NM_001190476.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 87bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-06-23 | |
| Organism | Homo sapiens(human) | |
| Product | humanin-like 4 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025283.6. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. CCDS Note: This gene represents one of several nuclear copies of the mitochondrial MT-RNR2 gene, which is transcribed as part of the 16S subunit of rRNA and can encode the neuroprotective peptide humanin. RT-PCR evidence in PMID:19477263 suggests that this nuclear gene copy is transcribed. The humanin protein has been detected in vivo (e.g., PMIDs 12009529, 19623253 and 20542501) but it is unclear if this protein is translated from mitochondrial or nuclear gene transcripts. Thus, there is some uncertainty about protein production from this nuclear gene copy. This CCDS is represented because protein production cannot be definitively ruled out for this gene. | |
1 | ATGGCCACAC AAGGGTTCAG CTGTCTCTTA CTTTCAGTCA GTGAAATTGA CCTATCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001177405.1 |
| CDS | 382..468 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001190476.1 |
1 | ATGGCCACAC AAGGGTTCAG CTGTCTCTTA CTTTCAGTCA GTGAAATTGA CCTATCCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The human mitochondrial genome may code for more than 13 proteins. |
Humanin: a harbinger of mitochondrial-derived peptides? |
Immunolocalization of humanin in human sperm and testis. |
Evidence for potential functionality of nuclearly-encoded humanin isoforms. |
Humanin: a novel central regulator of peripheral insulin action. |
