MAVS cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAVS
Entrez Gene ID	422936
Full Name	mitochondrial antiviral signaling protein
General protein information	Preferred Names mitochondrial antiviral signaling protein Names mitochondrial antiviral-signaling protein CARDIF
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012893.1	NP_001012911.1	mitochondrial antiviral-signaling protein

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Avian infectious bronchitis virus disrupts the melanoma differentiation associated gene 5 (MDA5) signaling pathway by cleavage of the adaptor protein MAVS.
Yu L, Zhang X, Wu T, Su J, Wang Y, Wang Y, Ruan B, Niu X, Wu Y
BMC veterinary research13(1)332(2017 Nov)

Genetic variations of mitochondrial antiviral signaling gene (MAVS) in domestic chickens.
Yu D, Xu L, Peng L, Chen SY, Liu YP, Yao YG
Gene545(2)226-32(2014 Jul)

Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2.
Liniger M, Summerfield A, Zimmer G, McCullough KC, Ruggli N
Journal of virology86(2)705-17(2012 Jan)

Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.
Caldwell RB, Kierzek AM, Arakawa H, Bezzubov Y, Zaim J, Fiedler P, Kutter S, Blagodatski A, Kostovska D, Koter M, Plachy J, Carninci P, Hayashizaki Y, Buerstedde JM
Genome biology6(1)R6(2005)

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype.
Jaillon O, Aury JM, Brunet F, Petit JL, Stange-Thomann N, Mauceli E, Bouneau L, Fischer C, Ozouf-Costaz C, Bernot A, Nicaud S, Jaffe D, Fisher S, Lutfalla G, Dossat C, Segurens B, Dasilva C, Salanoubat M, Levy M, Boudet N, Castellano S, Anthouard V, Jubin C, Castelli V, Katinka M, Vacherie B, Bi?mont C, Skalli Z, Cattolico L, Poulain J, De Berardinis V, Cruaud C, Duprat S, Brottier P, Coutanceau JP, Gouzy J, Parra G, Lardier G, Chapple C, McKernan KJ, McEwan P, Bosak S, Kellis M, Volff JN, Guig? R, Zody MC, Mesirov J, Lindblad-Toh K, Birren B, Nusbaum C, Kahn D, Robinson-Rechavi M, Laudet V, Schachter V, Qu?tier F, Saurin W, Scarpelli C, Wincker P, Lander ES, Weissenbach J, Roest Crollius H
Nature431(7011)946-57(2004 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a considerably high genetic variability of the MAVS gene, and the 3'-UTR variants had an ability to regulate mRNA expression. These results would cast some clues on understanding the potential role of MAVS on viral resistance in chicken
Title: Genetic variations of mitochondrial antiviral signaling gene (MAVS) in domestic chickens.

Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2.
Title: Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2.

The following MAVS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAVS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa26618	NM_001012893.1 Latest version!	Gallus gallus mitochondrial antiviral signaling protein (MAVS), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAVS ( NM_001012893.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001012911.1 Gallus gallus mitochondrial antiviral signaling protein (MAVS), mRNA.

Price & Availability↑

CloneID	OGa26618
Clone ID Related Accession (Same CDS sequence)	NM_001012893.1
Accession Version	NM_001012893.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-20
Organism	Gallus gallus(chicken)
Product	mitochondrial antiviral-signaling protein
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ851605.1. On Mar 14, 2005 this sequence version replaced XM_420874.1. ##Evidence-Data-START## Transcript exon combination :: AJ851605.1, HQ845772.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGGTTTCG CCGAGGACAA AGTGTATAAC CACATCCTGA GGAACATGAG CAGGTTCTGT 
GACATCCACG TGGCGTCGCT GGTCGATTCC CTGAGCTGCC TCACCGATGC CGACAGGGAT 
GAGCTTCACA CCCGGCAGGA TATGCGGGGG ATCCGTGCGA CTGCATACAA ATTTTACCAG 
CACCTGAAGT GCCGAAAGGG CTGGGTGATG GATCTGATCA ATGCGCTGCA CCAGAACAAT 
GCAGGGCACC TGGCTGAGGA GCTGCAGCGG GTTTATGACT GCTACCAAGC CCCTCCTCCA 
GGTGCCTCAG CTCCTCCAAG TGCTTCAGCT CCTGCTGCCT GGCCTGCTGT TTCCTCCAGC 
AGTGTCCCGA AGCCGTTCCC AGGGCCAAAC TCTGCTGCAG AAGCCCCAAT GGCTGAGCCA 
CCACGCTACA ACCCATCTGC TGGTGGCCGT CCACCCCTCT CACCTGCTGC TGCCACCACT 
GCGACCTCAG CTGTGAGCTC GGATGTTTCC AGCACAGAGC TGGATGCCAG GGCCCCGGTG 
CAGGAAACGC CCCCAGAAAG AAAGAGTCCT CAGCCACCGC TGATGACAAG CACGGTCTGT 
GATGGCAAAG AGAAACCTCT CCCATACCCC ACCAGTGAGC AGCAAGAGGC AGTGGAGACC 
CCTGGGACAT CCAGCACAGT TTTGCCATCT GTGTCCCCTG AGCAGGGCCA GGAGTGGCTG 
AGCCATCGGC ATCCAGTGTG CGTGGACAAC GGGTGTTTTG GGAACGCAAA CCACCTTCAA 
CGTGGCATGC CAAACTTGGA TCTGAGCAGG TCTCTTCCAC CAAGGGATTT GAGTGCTGCT 
CCTGGCCCTG AGCAGACCAG AAACGAGCCC CAGGAAGACG TCTACATCTC CAGTGAGTTG 
CCAGTGAGGT TGGTGGAGAC CACTGATGGT GGGGGACCGC AGCCCCCAGA CTCTGTGAGG 
ACACAGGAGG AACGAGCTGT GCACAGTTTT AAGCACGATG GACCCCCGAG CAGCTTTGTG 
GATGTGCGCA ACCCCTTACT TATACAACAG CAGTTTGATG CAGAGCAGAA GCAGATTGAG 
AGAGAGCATG AAGGAGGTGG AGATGTTTTG AAGGAAACAA CCACCTCAGT CTCTACCTCT 
GCACCCCAAG ATATTTCCCC ATTCTGTGAC ACCTCCTTGA AGCCTCCTGT ACGAGAGAAA 
ATGCTGCCTG AGGAGAAAGC AGCCAGCAGC ACCCCCTCCA TGCCAGGGAA GGAGAAAGTG 
CTCTCGGCCT CGGTGGCCTC CCTGTCAGGT ATGAATGCTG CAGGAAGCTT TGAAGGTGCA 
GCTGGGAGGA CCTCCTCACA AGTGAGCTCT GCTGCCAGCA TCTGGGCATC TCATGATAAC 
GAGGAGGAAG ACGTGGAGCT CAGCAAGCCA GGTGCCCTCC AGTCTGTAGT AGGAGAGAGC 
CCAAAGGCAG CTGCCAGATA CCCGGGCAGC CCCAGTTCCA ACACATCCAG TCACCTTGGC 
TTGAGCAGCG ACCCGATCAT GGTGAGCACA GACAGCTTGA GGCCTGGAGA AGCACAGTCC 
ACAGCCAACT CAGGGCTCTG GTCTGCAACT CCAGCAGTTC ATGCAGACCC TGGGGGAGAA 
GAGGCAGCTG GAGTGAGCCC TTATCCACCT CTGAGCTGGG CTGACCCCTC TGTGGGCACC 
CACGAGGTCC ATGTGGAGCA TCACCCCAGT GCCCCGCTCA CAGCAGGCAA TGATGTCCCA 
GATGAAGCAG TCCCCTATGG AGACTCTCCT GACTCAAACA AGGGAAGTAA TGCTGCAAAC 
AACTCATCTC ACGCCGAAGT CCCCACATCA GGGGACAGCA ATGGGCCGTC TCTGCTGTAC 
ATCCTTCCAG CTGTTGGCAT CGCTCTGATT TCAGTGTTTC TGGTGTACAC ACGATTGCAG 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012911.1
CDS	147..2072
Translation	MGFAEDKVYNHILRNMSRFCDIHVASLVDSLSCLTDADRDELHTRQDMRGIRATAYKFYQHLKCRKGWVMDLINALHQNNAGHLAEELQRVYDCYQAPPPGASAPPSASAPAAWPAVSSSSVPKPFPGPNSAAEAPMAEPPRYNPSAGGRPPLSPAAATTATSAVSSDVSSTELDARAPVQETPPERKSPQPPLMTSTVCDGKEKPLPYPTSEQQEAVETPGTSSTVLPSVSPEQGQEWLSHRHPVCVDNGCFGNANHLQRGMPNLDLSRSLPPRDLSAAPGPEQTRNEPQEDVYISSELPVRLVETTDGGGPQPPDSVRTQEERAVHSFKHDGPPSSFVDVRNPLLIQQQFDAEQKQIEREHEGGGDVLKETTTSVSTSAPQDISPFCDTSLKPPVREKMLPEEKAASSTPSMPGKEKVLSASVASLSGMNAAGSFEGAAGRTSSQVSSAASIWASHDNEEEDVELSKPGALQSVVGESPKAAARYPGSPSSNTSSHLGLSSDPIMVSTDSLRPGEAQSTANSGLWSATPAVHADPGGEEAAGVSPYPPLSWADPSVGTHEVHVEHHPSAPLTAGNDVPDEAVPYGDSPDSNKGSNAANNSSHAEVPTSGDSNGPSLLYILPAVGIALISVFLVYTRLQK

Target ORF information:

RefSeq Version	NM_001012893.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus mitochondrial antiviral signaling protein (MAVS), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012893.1

ORF Insert Sequence:

ATGGGTTTCG CCGAGGACAA AGTGTATAAC CACATCCTGA GGAACATGAG CAGGTTCTGT 
GACATCCACG TGGCGTCGCT GGTCGATTCC CTGAGCTGCC TCACCGATGC CGACAGGGAT 
GAGCTTCACA CCCGGCAGGA TATGCGGGGG ATCCGTGCGA CTGCATACAA ATTTTACCAG 
CACCTGAAGT GCCGAAAGGG CTGGGTGATG GATCTGATCA ATGCGCTGCA CCAGAACAAT 
GCAGGGCACC TGGCTGAGGA GCTGCAGCGG GTTTATGACT GCTACCAAGC CCCTCCTCCA 
GGTGCCTCAG CTCCTCCAAG TGCTTCAGCT CCTGCTGCCT GGCCTGCTGT TTCCTCCAGC 
AGTGTCCCGA AGCCGTTCCC AGGGCCAAAC TCTGCTGCAG AAGCCCCAAT GGCTGAGCCA 
CCACGCTACA ACCCATCTGC TGGTGGCCGT CCACCCCTCT CACCTGCTGC TGCCACCACT 
GCGACCTCAG CTGTGAGCTC GGATGTTTCC AGCACAGAGC TGGATGCCAG GGCCCCGGTG 
CAGGAAACGC CCCCAGAAAG AAAGAGTCCT CAGCCACCGC TGATGACAAG CACGGTCTGT 
GATGGCAAAG AGAAACCTCT CCCATACCCC ACCAGTGAGC AGCAAGAGGC AGTGGAGACC 
CCTGGGACAT CCAGCACAGT TTTGCCATCT GTGTCCCCTG AGCAGGGCCA GGAGTGGCTG 
AGCCATCGGC ATCCAGTGTG CGTGGACAAC GGGTGTTTTG GGAACGCAAA CCACCTTCAA 
CGTGGCATGC CAAACTTGGA TCTGAGCAGG TCTCTTCCAC CAAGGGATTT GAGTGCTGCT 
CCTGGCCCTG AGCAGACCAG AAACGAGCCC CAGGAAGACG TCTACATCTC CAGTGAGTTG 
CCAGTGAGGT TGGTGGAGAC CACTGATGGT GGGGGACCGC AGCCCCCAGA CTCTGTGAGG 
ACACAGGAGG AACGAGCTGT GCACAGTTTT AAGCACGATG GACCCCCGAG CAGCTTTGTG 
GATGTGCGCA ACCCCTTACT TATACAACAG CAGTTTGATG CAGAGCAGAA GCAGATTGAG 
AGAGAGCATG AAGGAGGTGG AGATGTTTTG AAGGAAACAA CCACCTCAGT CTCTACCTCT 
GCACCCCAAG ATATTTCCCC ATTCTGTGAC ACCTCCTTGA AGCCTCCTGT ACGAGAGAAA 
ATGCTGCCTG AGGAGAAAGC AGCCAGCAGC ACCCCCTCCA TGCCAGGGAA GGAGAAAGTG 
CTCTCGGCCT CGGTGGCCTC CCTGTCAGGT ATGAATGCTG CAGGAAGCTT TGAAGGTGCA 
GCTGGGAGGA CCTCCTCACA AGTGAGCTCT GCTGCCAGCA TCTGGGCATC TCATGATAAC 
GAGGAGGAAG ACGTGGAGCT CAGCAAGCCA GGTGCCCTCC AGTCTGTAGT AGGAGAGAGC 
CCAAAGGCAG CTGCCAGATA CCCGGGCAGC CCCAGTTCCA ACACATCCAG TCACCTTGGC 
TTGAGCAGCG ACCCGATCAT GGTGAGCACA GACAGCTTGA GGCCTGGAGA AGCACAGTCC 
ACAGCCAACT CAGGGCTCTG GTCTGCAACT CCAGCAGTTC ATGCAGACCC TGGGGGAGAA 
GAGGCAGCTG GAGTGAGCCC TTATCCACCT CTGAGCTGGG CTGACCCCTC TGTGGGCACC 
CACGAGGTCC ATGTGGAGCA TCACCCCAGT GCCCCGCTCA CAGCAGGCAA TGATGTCCCA 
GATGAAGCAG TCCCCTATGG AGACTCTCCT GACTCAAACA AGGGAAGTAA TGCTGCAAAC 
AACTCATCTC ACGCCGAAGT CCCCACATCA GGGGACAGCA ATGGGCCGTC TCTGCTGTAC 
ATCCTTCCAG CTGTTGGCAT CGCTCTGATT TCAGTGTTTC TGGTGTACAC ACGATTGCAG 
AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Avian infectious bronchitis virus disrupts the melanoma differentiation associated gene 5 (MDA5) signaling pathway by cleavage of the adaptor protein MAVS.
BMC veterinary research13(1)332(2017 Nov)
Yu L,Zhang X,Wu T,Su J,Wang Y,Wang Y,Ruan B,Niu X,Wu Y

Genetic variations of mitochondrial antiviral signaling gene (MAVS) in domestic chickens.
Gene545(2)226-32(2014 Jul)
Yu D,Xu L,Peng L,Chen SY,Liu YP,Yao YG

Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2.
Journal of virology86(2)705-17(2012 Jan)
Liniger M,Summerfield A,Zimmer G,McCullough KC,Ruggli N

Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.
Genome biology6(1)R6(2005)
Caldwell RB,Kierzek AM,Arakawa H,Bezzubov Y,Zaim J,Fiedler P,Kutter S,Blagodatski A,Kostovska D,Koter M,Plachy J,Carninci P,Hayashizaki Y,Buerstedde JM

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype.
Nature431(7011)946-57(2004 Oct)
Jaillon O,Aury JM,Brunet F,Petit JL,Stange-Thomann N,Mauceli E,Bouneau L,Fischer C,Ozouf-Costaz C,Bernot A,Nicaud S,Jaffe D,Fisher S,Lutfalla G,Dossat C,Segurens B,Dasilva C,Salanoubat M,Levy M,Boudet N,Castellano S,Anthouard V,Jubin C,Castelli V,Katinka M,Vacherie B,Bi?mont C,Skalli Z,Cattolico L,Poulain J,De Berardinis V,Cruaud C,Duprat S,Brottier P,Coutanceau JP,Gouzy J,Parra G,Lardier G,Chapple C,McKernan KJ,McEwan P,Bosak S,Kellis M,Volff JN,Guig? R,Zody MC,Mesirov J,Lindblad-Toh K,Birren B,Nusbaum C,Kahn D,Robinson-Rechavi M,Laudet V,Schachter V,Qu?tier F,Saurin W,Scarpelli C,Wincker P,Lander ES,Weissenbach J,Roest Crollius H

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MAVS cDNA ORF clone, Gallus gallus(chicken)

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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