IGF1 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	IGF1
Entrez Gene ID	418090
Full Name	insulin like growth factor 1
Synonyms	IGF-1,IGF-I
General protein information	Preferred Names insulin like growth factor 1 Names insulin-like growth factor I insulin-like growth factor 1 (somatomedin C) somatomedin
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001004384.2	NP_001004384.1	insulin-like growth factor I preproprotein

Pathways from BioSystems

Homologies

	IGF1	XP_001094251.1
Canis lupus familiaris (dog)	IGF1	XP_853117.1
Rattus norvegicus (Norway rat)	Igf1	NP_001075948.1
Gallus gallus (chicken)	IGF1	NP_001004384.1
Homo sapiens (human)	IGF1	NP_000609.1
Pan troglodytes (chimpanzee)	IGF1	XP_001156521.1
Mus musculus (house mouse)	Igf1	NP_001104745.1
Bos taurus (cattle)	IGF1	NP_001071296.1
Danio rerio (zebrafish)	igf1	NP_571900.1
Xenopus tropicalis (tropical clawed frog)	LOC100486334	XP_002936875.1

Gene Ontology
Bibliography

Related articles in PubMed

The IGF-1/Akt/S6 pathway and expressions of glycolytic myosin heavy chain isoforms are upregulated in chicken skeletal muscle during the first week after hatching.
Saneyasu T, Tsuchihashi T, Kitashiro A, Tsuchii N, Kimura S, Honda K, Kamisoyama H
Animal science journal = Nihon chikusan Gakkaiho88(11)1779-1787(2017 Nov)

Melatonin Mediates Monochromatic Light-induced Insulin-like Growth Factor 1 Secretion of Chick Liver: Involvement of Membrane Receptors.
Li S, Cao J, Wang Z, Dong Y, Wang W, Chen Y
Photochemistry and photobiology92(4)595-603(2016 07)

Developmental changes of Insulin-like growth factors in the liver and muscle of chick embryos.
Liu Y, Guo W, Pu Z, Li X, Lei X, Yao J, Yang X
Poultry science95(6)1396-402(2016 Jun)

Polymorphism and expression of insulin-like growth factor 1 (IGF1) gene and its association with growth traits in chicken.
Bhattacharya TK, Chatterjee RN, Dushyanth K, Paswan C, Shukla R, Shanmugam M
British poultry science56(4)398-407(2015)

Insulin-like growth factor I gene polymorphism associated with growth and carcass traits in Thai synthetic chickens.
Promwatee N, Laopaiboon B, Vongpralub T, Phasuk Y, Kunhareang S, Boonkum W, Duangjinda M
Genetics and molecular research : GMR12(4)4332-41(2013 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings demonstrated that MEL mediated the monochromatic light-induced secretion of IGF-1 in chicks' livers by Mel1c and that Mel1a may be involved in this process.
Title: Melatonin Mediates Monochromatic Light-induced Insulin-like Growth Factor 1 Secretion of Chick Liver: Involvement of Membrane Receptors.

IGF1 and IGF2 might separately be more important for muscle and liver growth in chick embryonic development. Variation of IGFs expression during the incubation might be concerned with the methylation of gene promoter.
Title: Developmental changes of Insulin-like growth factors in the liver and muscle of chick embryos.

The coding region of the IGF1 gene was polymorphic, expressed differentially during the pre-hatch and post-hatch periods, and haplogroups showed significant association with growth traits in chicken.
Title: Polymorphism and expression of insulin-like growth factor 1 (IGF1) gene and its association with growth traits in chicken.

The IGF-I gene is significantly associated with some growth traits (body weight at hatching, and at 4, 8, 12, and 14 weeks of age) in chickens.
Title: Insulin-like growth factor I gene polymorphism associated with growth and carcass traits in Thai synthetic chickens.

IGF1 single-nucleotide polymorphism c.47673G > A was associated with body weight and haematocrit percentage, and also with feed intake and percentages of abdominal fat and gizzard genotype x sex interactions.
Title: Association of IGF1 and KDM5A polymorphisms with performance, fatness and carcass traits in chickens.

The following IGF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IGF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa28149	NM_001004384.2 Latest version!	Gallus gallus insulin like growth factor 1 (IGF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IGF1 ( NM_001004384.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001004384.1 Gallus gallus insulin like growth factor 1 (IGF1), mRNA.

Price & Availability↑

CloneID	OGa28149
Clone ID Related Accession (Same CDS sequence)	NM_001004384.2
Accession Version	NM_001004384.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 462bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Gallus gallus(chicken)
Product	insulin-like growth factor I preproprotein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from M32791.1 and BU454475.1. On Jun 2, 2010 this sequence version replaced NM_001004384.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M32791.1, FJ977570.1 [ECO:0000332] ##Evidence-Data-END##

ATGGAAAAAA TCAACAGTCT TTCAACACAA TTAGTTAAGT GCTGCTTTTG TGATTTCTTG 
AAGGTGAAGA TGCACACTGT GTCCTACATT CATTTCTTCT ACCTTGGCCT GTGTTTGCTT 
ACCTTAACCA GTTCTGCTGC TGCCGGCCCA GAAACACTGT GTGGTGCTGA GCTGGTTGAT 
GCTCTTCAGT TCGTATGTGG AGACAGAGGC TTCTACTTCA GTAAGCCTAC AGGGTATGGA 
TCCAGCAGTA GACGCTTACA CCACAAGGGA ATAGTGGATG AATGCTGCTT CCAGAGTTGT 
GACCTGAGGA GGCTGGAGAT GTACTGTGCT CCAATAAAGC CACCTAAATC TGCACGCTCT 
GTACGTGCTC AGCGCCACAC TGATATGCCA AAAGCACAAA AGGAAGTGCA TTTGAAGAAT 
ACAAGTAGAG GGAACACAGG AAACAGAAAC TACAGAATGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004384.1
CDS	247..708
Translation	MEKINSLSTQLVKCCFCDFLKVKMHTVSYIHFFYLGLCLLTLTSSAAAGPETLCGAELVDALQFVCGDRGFYFSKPTGYGSSSRRLHHKGIVDECCFQSCDLRRLEMYCAPIKPPKSARSVRAQRHTDMPKAQKEVHLKNTSRGNTGNRNYRM

Target ORF information:

RefSeq Version	NM_001004384.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus insulin like growth factor 1 (IGF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004384.2

ORF Insert Sequence:

ATGGAAAAAA TCAACAGTCT TTCAACACAA TTAGTTAAGT GCTGCTTTTG TGATTTCTTG 
AAGGTGAAGA TGCACACTGT GTCCTACATT CATTTCTTCT ACCTTGGCCT GTGTTTGCTT 
ACCTTAACCA GTTCTGCTGC TGCCGGCCCA GAAACACTGT GTGGTGCTGA GCTGGTTGAT 
GCTCTTCAGT TCGTATGTGG AGACAGAGGC TTCTACTTCA GTAAGCCTAC AGGGTATGGA 
TCCAGCAGTA GACGCTTACA CCACAAGGGA ATAGTGGATG AATGCTGCTT CCAGAGTTGT 
GACCTGAGGA GGCTGGAGAT GTACTGTGCT CCAATAAAGC CACCTAAATC TGCACGCTCT 
GTACGTGCTC AGCGCCACAC TGATATGCCA AAAGCACAAA AGGAAGTGCA TTTGAAGAAT 
ACAAGTAGAG GGAACACAGG AAACAGAAAC TACAGAATGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The IGF-1/Akt/S6 pathway and expressions of glycolytic myosin heavy chain isoforms are upregulated in chicken skeletal muscle during the first week after hatching.
Animal science journal = Nihon chikusan Gakkaiho88(11)1779-1787(2017 Nov)
Saneyasu T,Tsuchihashi T,Kitashiro A,Tsuchii N,Kimura S,Honda K,Kamisoyama H

Melatonin Mediates Monochromatic Light-induced Insulin-like Growth Factor 1 Secretion of Chick Liver: Involvement of Membrane Receptors.
Photochemistry and photobiology92(4)595-603(2016 07)
Li S,Cao J,Wang Z,Dong Y,Wang W,Chen Y

Developmental changes of Insulin-like growth factors in the liver and muscle of chick embryos.
Poultry science95(6)1396-402(2016 Jun)
Liu Y,Guo W,Pu Z,Li X,Lei X,Yao J,Yang X

Polymorphism and expression of insulin-like growth factor 1 (IGF1) gene and its association with growth traits in chicken.
British poultry science56(4)398-407(2015)
Bhattacharya TK,Chatterjee RN,Dushyanth K,Paswan C,Shukla R,Shanmugam M

Insulin-like growth factor I gene polymorphism associated with growth and carcass traits in Thai synthetic chickens.
Genetics and molecular research : GMR12(4)4332-41(2013 Mar)
Promwatee N,Laopaiboon B,Vongpralub T,Phasuk Y,Kunhareang S,Boonkum W,Duangjinda M

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IGF1 cDNA ORF clone, Gallus gallus(chicken)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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