HNF1A cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	HNF1A
Entrez Gene ID	416967
Full Name	HNF1 homeobox A
Synonyms	HNF-1-alpha,HNF-1A,HNF-1alpha,LF-B1,TCF-1,TCF1
General protein information	Preferred Names HNF1 homeobox A Names hepatocyte nuclear factor 1-alpha albumin proximal factor hepatic nuclear factor (HNF1) transcription factor 1, hepatic transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001030668.2	NP_001025839.2	hepatocyte nuclear factor 1-alpha

Pathways from BioSystems

Homologies

Homo sapiens (human)	HNF1A	NP_000536.5
Rattus norvegicus (Norway rat)	Hnf1a	NP_036801.1
Canis lupus familiaris (dog)	HNF1A	XP_543429.2
	LOC701243	XP_001089567.1
Pan troglodytes (chimpanzee)	HNF1A	XP_001148554.2
Danio rerio (zebrafish)	hnf1a	NP_739570.1
Bos taurus (cattle)	HNF1A	NP_001179453.1
Mus musculus (house mouse)	Hnf1a	NP_033353.2
Gallus gallus (chicken)	HNF1A	NP_001025839.2
Xenopus tropicalis (tropical clawed frog)	hnf1a	NP_001116920.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional defect of truncated hepatocyte nuclear factor-1alpha (G554fsX556) associated with maturity-onset diabetes of the young.
Kooptiwut S, Sujjitjoon J, Plengvidhya N, Boonyasrisawat W, Chongjaroen N, Jungtrakoon P, Semprasert N, Furuta H, Nanjo K, Banchuin N, Yenchitsomanus PT
Biochemical and biophysical research communications383(1)68-72(2009 May)

vHnf1 regulates specification of caudal rhombomere identity in the chick hindbrain.
Arag?n F, V?zquez-Echeverr?a C, Ulloa E, Reber M, Cereghini S, Alsina B, Giraldez F, Pujades C
Developmental dynamics : an official publication of the American Association of Anatomists234(3)567-76(2005 Nov)

Genomic structure of the POU-related hepatic transcription factor HNF-1 alpha.
H?rlein A, Grajer KH, Igo-Kemenes T
Biological chemistry Hoppe-Seyler374(7)419-25(1993 Jul)

Hepatic nuclear factor 1 alpha (HNF-1 alpha) is expressed in the oviduct of hens and interacts with regulatory elements of the lysozyme gene.
Grajer KH, H?rlein A, Igo-Kemenes T
Biological chemistry Hoppe-Seyler374(5)319-26(1993 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggested that the functional defect of novel truncated HNF-1alpha (G554fsX556) on the transactivation of its target-gene promoters would account for the beta-cell dysfunction associated with the pathogenesis of MODY
Title: Functional defect of truncated hepatocyte nuclear factor-1alpha (G554fsX556) associated with maturity-onset diabetes of the young.

variant Hnf1 acts with fibroblast growth factor to promote caudal hindbrain identity by activating MafB and Kro x 20 expression
Title: vHnf1 regulates specification of caudal rhombomere identity in the chick hindbrain.

The following HNF1A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HNF1A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00172	NM_001030668.2 Latest version!	Gallus gallus HNF1 homeobox A (HNF1A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HNF1A ( NM_001030668.2 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_001025839.2 Gallus gallus HNF1 homeobox A (HNF1A), mRNA.

Price & Availability↑

CloneID	OGa00172
Clone ID Related Accession (Same CDS sequence)	NM_001030668.2
Accession Version	NM_001030668.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1905bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Gallus gallus(chicken)
Product	hepatocyte nuclear factor 1-alpha
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC160646.2. On Feb 1, 2013 this sequence version replaced NM_001030668.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on X67689.1 and X67690.1 and PubMed ID: 8105803. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2201359, SAMEA2201360 [ECO:0000350] ##Evidence-Data-END##

ATGGTCTCGA AGCTGAGCCA TCTTCAAGTG GAGCTGCTGG GAGCGCTGCT GGAGTCGGGG 
CTAACCAAGG AGACCCTGAT CAAGGCGCTG AGCGAAGCGG AACCCTACGT GCTCCAGAGT 
GAAAGTCAGC ATGCTATCAA TGCCCTGCAG ACAGAGAAAG GGGAGTCCTG CCCCGAGATC 
CCCAACCTCC CCAATGGAAT GGGGGAAACC AGGTTATCGG AAGATGAAAC CTCTGATGAC 
GGGGAGGAAT TTACCCCTCC GATAATGAAG GAGCTGGAAA ACTTGAGCCC TGAGGAGGCT 
GCTCACCAGA AGGCTGTGGT GGAAAGACTA TTACAAGAGG ATCCCTGGCG GGTGGCAAAG 
ATGGTGAAAT CCTACCTCCA ACAGCACAAC ATCCCTCAGC GCGAGGTGGT GGACACGACC 
GGTCTGAACC AATCCCACCT CTCACAACAC CTCAACAAGG GCACTCCCAT GAAGACCCAG 
AAAAGGGCAG CCCTCTACAC CTGGTACGTC CGCAAGCAGC GAGAGGTGGC CCAGCAGTTC 
ACACATGCTG GTCAGGGGAT ATTGACAGAG GAGCCCATGG GAGATGATCT GCCCACCAAG 
AAGGGACGAA GAAATCGCTT TAAGTGGGGT CCTGCCTCAC AACAGATTCT GTTCCAAGCC 
TATGAGAGAC AGAAGAACCC CAGCAAAGAA GAGAGAGAGG CGCTGGTAGA AGAGTGCAAC 
AGAGCAGAGT GTATTCAGAG AGGCGTTTCC CCATCTCAGG CCCAGGGTCT GGGCTCAAAC 
CTGGTGACCG AGGTGCGAGT TTACAACTGG TTTGCCAACC GCAGGAAGGA GGAGGCCTTC 
CGGCACAAGC TGGCCATGGA CAACTTCAGC GGGCCGCAGC CCACCTCCGC TCCCCCTCTA 
ACTCCTCACA ACTCTTCCTC CCTTCAACCA CCTCCTGCTC TCTCACCCAC CAAAGTTCAT 
GGAGTGAGGT ACAACCAGCA GCCAGCCAGT GAGGCAGAGT CCTCCAGCAG CAACCACCAC 
GGGAACAGCT CCATGGTGAC CACCCAAACC ATCCTGCACC AGGTTTCTCC CCCTGGGCTG 
GAGCCCAGCC AGAACCTACT GAGCACAGAC ACCAAGCTGA TCTCAGCTCC CGGAGGAACT 
CTGCCCCCCG TCAGCACCCT GACTGCCCTG CACAGCCTGG AGCAAAACCC CCACGCGCTG 
GGCCAGCAAA CTCAGAACCT CATCATGGCC TCACTGCCCG GCGTGATGGC AATCGGAGCC 
GGTGAGACCT CATCCCTGGC ACCCGCGTTC ACCAACACCG GCGGCTCCAC CCTGGTGATA 
GGCCTGACTT CAACCCAGCC CCAGAGCGTA CCTGTGATAA ATAGCATGGG GAGCAGCCTC 
ACCACCCTGC AGCCAGTCCA GTTCTCCCAG CAGCTGCACC CGTCCTACCA GCAGCCCCTC 
ATGCAGCAGG TCCAGAGCCA CATCAACCAG AGCCCCTTCA TGGCTACCAT GGCCCAGATA 
CAGAACCCCC ACGCTCTCTA CGGCCCCAAG TCTGAAGTGG CCCAATACAC GCACACAGGC 
CTCCTACCAC AAACCATGGT GATAACGGAT ACAGCCAACC TCAGCGCCCT GACTAACCTG 
ACACCAACTA AACAGGCATT CACATCTGAC TCAGAAACCC ACACAGACTC TGGGATCCAT 
ACACCAGTAT CACAGGCACC AGCGATACAT CTACAGAACC AAGACACAGC CATCCAGCAC 
CTTCAGTCTG GCCCTCGCCT CACCCCAAGC CCTGCTGTGT CCTCCAGCAG CCTGGTGCTG 
TACCAGAGCT CTGACTCCAC CAACAGCCAC AGTCAGCTGC TGCCATCCAC TCATAACGTC 
ATTGAGACCT TCATCTCCAC GCAGATGGCA TCCTCCACTC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001025839.2
CDS	141..2045
Translation	MVSKLSHLQVELLGALLESGLTKETLIKALSEAEPYVLQSESQHAINALQTEKGESCPEIPNLPNGMGETRLSEDETSDDGEEFTPPIMKELENLSPEEAAHQKAVVERLLQEDPWRVAKMVKSYLQQHNIPQREVVDTTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREVAQQFTHAGQGILTEEPMGDDLPTKKGRRNRFKWGPASQQILFQAYERQKNPSKEEREALVEECNRAECIQRGVSPSQAQGLGSNLVTEVRVYNWFANRRKEEAFRHKLAMDNFSGPQPTSAPPLTPHNSSSLQPPPALSPTKVHGVRYNQQPASEAESSSSNHHGNSSMVTTQTILHQVSPPGLEPSQNLLSTDTKLISAPGGTLPPVSTLTALHSLEQNPHALGQQTQNLIMASLPGVMAIGAGETSSLAPAFTNTGGSTLVIGLTSTQPQSVPVINSMGSSLTTLQPVQFSQQLHPSYQQPLMQQVQSHINQSPFMATMAQIQNPHALYGPKSEVAQYTHTGLLPQTMVITDTANLSALTNLTPTKQAFTSDSETHTDSGIHTPVSQAPAIHLQNQDTAIQHLQSGPRLTPSPAVSSSSLVLYQSSDSTNSHSQLLPSTHNVIETFISTQMASSTQ

Target ORF information:

RefSeq Version	NM_001030668.2
Organism	Gallus gallus(chicken)
Definition	Gallus gallus HNF1 homeobox A (HNF1A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001030668.2

ORF Insert Sequence:

ATGGTCTCGA AGCTGAGCCA TCTTCAAGTG GAGCTGCTGG GAGCGCTGCT GGAGTCGGGG 
CTAACCAAGG AGACCCTGAT CAAGGCGCTG AGCGAAGCGG AACCCTACGT GCTCCAGAGT 
GAAAGTCAGC ATGCTATCAA TGCCCTGCAG ACAGAGAAAG GGGAGTCCTG CCCCGAGATC 
CCCAACCTCC CCAATGGAAT GGGGGAAACC AGGTTATCGG AAGATGAAAC CTCTGATGAC 
GGGGAGGAAT TTACCCCTCC GATAATGAAG GAGCTGGAAA ACTTGAGCCC TGAGGAGGCT 
GCTCACCAGA AGGCTGTGGT GGAAAGACTA TTACAAGAGG ATCCCTGGCG GGTGGCAAAG 
ATGGTGAAAT CCTACCTCCA ACAGCACAAC ATCCCTCAGC GCGAGGTGGT GGACACGACC 
GGTCTGAACC AATCCCACCT CTCACAACAC CTCAACAAGG GCACTCCCAT GAAGACCCAG 
AAAAGGGCAG CCCTCTACAC CTGGTACGTC CGCAAGCAGC GAGAGGTGGC CCAGCAGTTC 
ACACATGCTG GTCAGGGGAT ATTGACAGAG GAGCCCATGG GAGATGATCT GCCCACCAAG 
AAGGGACGAA GAAATCGCTT TAAGTGGGGT CCTGCCTCAC AACAGATTCT GTTCCAAGCC 
TATGAGAGAC AGAAGAACCC CAGCAAAGAA GAGAGAGAGG CGCTGGTAGA AGAGTGCAAC 
AGAGCAGAGT GTATTCAGAG AGGCGTTTCC CCATCTCAGG CCCAGGGTCT GGGCTCAAAC 
CTGGTGACCG AGGTGCGAGT TTACAACTGG TTTGCCAACC GCAGGAAGGA GGAGGCCTTC 
CGGCACAAGC TGGCCATGGA CAACTTCAGC GGGCCGCAGC CCACCTCCGC TCCCCCTCTA 
ACTCCTCACA ACTCTTCCTC CCTTCAACCA CCTCCTGCTC TCTCACCCAC CAAAGTTCAT 
GGAGTGAGGT ACAACCAGCA GCCAGCCAGT GAGGCAGAGT CCTCCAGCAG CAACCACCAC 
GGGAACAGCT CCATGGTGAC CACCCAAACC ATCCTGCACC AGGTTTCTCC CCCTGGGCTG 
GAGCCCAGCC AGAACCTACT GAGCACAGAC ACCAAGCTGA TCTCAGCTCC CGGAGGAACT 
CTGCCCCCCG TCAGCACCCT GACTGCCCTG CACAGCCTGG AGCAAAACCC CCACGCGCTG 
GGCCAGCAAA CTCAGAACCT CATCATGGCC TCACTGCCCG GCGTGATGGC AATCGGAGCC 
GGTGAGACCT CATCCCTGGC ACCCGCGTTC ACCAACACCG GCGGCTCCAC CCTGGTGATA 
GGCCTGACTT CAACCCAGCC CCAGAGCGTA CCTGTGATAA ATAGCATGGG GAGCAGCCTC 
ACCACCCTGC AGCCAGTCCA GTTCTCCCAG CAGCTGCACC CGTCCTACCA GCAGCCCCTC 
ATGCAGCAGG TCCAGAGCCA CATCAACCAG AGCCCCTTCA TGGCTACCAT GGCCCAGATA 
CAGAACCCCC ACGCTCTCTA CGGCCCCAAG TCTGAAGTGG CCCAATACAC GCACACAGGC 
CTCCTACCAC AAACCATGGT GATAACGGAT ACAGCCAACC TCAGCGCCCT GACTAACCTG 
ACACCAACTA AACAGGCATT CACATCTGAC TCAGAAACCC ACACAGACTC TGGGATCCAT 
ACACCAGTAT CACAGGCACC AGCGATACAT CTACAGAACC AAGACACAGC CATCCAGCAC 
CTTCAGTCTG GCCCTCGCCT CACCCCAAGC CCTGCTGTGT CCTCCAGCAG CCTGGTGCTG 
TACCAGAGCT CTGACTCCAC CAACAGCCAC AGTCAGCTGC TGCCATCCAC TCATAACGTC 
ATTGAGACCT TCATCTCCAC GCAGATGGCA TCCTCCACTC AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional defect of truncated hepatocyte nuclear factor-1alpha (G554fsX556) associated with maturity-onset diabetes of the young.
Biochemical and biophysical research communications383(1)68-72(2009 May)
Kooptiwut S,Sujjitjoon J,Plengvidhya N,Boonyasrisawat W,Chongjaroen N,Jungtrakoon P,Semprasert N,Furuta H,Nanjo K,Banchuin N,Yenchitsomanus PT

vHnf1 regulates specification of caudal rhombomere identity in the chick hindbrain.
Developmental dynamics : an official publication of the American Association of Anatomists234(3)567-76(2005 Nov)
Arag?n F,V?zquez-Echeverr?a C,Ulloa E,Reber M,Cereghini S,Alsina B,Giraldez F,Pujades C

Genomic structure of the POU-related hepatic transcription factor HNF-1 alpha.
Biological chemistry Hoppe-Seyler374(7)419-25(1993 Jul)
H?rlein A,Grajer KH,Igo-Kemenes T

Hepatic nuclear factor 1 alpha (HNF-1 alpha) is expressed in the oviduct of hens and interacts with regulatory elements of the lysozyme gene.
Biological chemistry Hoppe-Seyler374(5)319-26(1993 May)
Grajer KH,H?rlein A,Igo-Kemenes T