CCDC80 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCDC80
Entrez Gene ID	395074
Full Name	coiled-coil domain containing 80
Synonyms	cequarin,equarin-S
General protein information	Preferred Names coiled-coil domain containing 80 Names coiled-coil domain-containing protein 80 coiled-coil domain-containing protein 80oiled-coil domain-containing protein 80 equarin equarin-L
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_204431.1	NP_989762.1	coiled-coil domain-containing protein 80 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	CCDC80	NP_955805.1
Mus musculus (house mouse)	Ccdc80	NP_080715.2
Danio rerio (zebrafish)	ccdc80	NP_001007199.1
Canis lupus familiaris (dog)	CCDC80	XP_005639700.1
Rattus norvegicus (Norway rat)	Ccdc80	NP_071988.2
Pan troglodytes (chimpanzee)	CCDC80	XP_001156251.2
	CCDC80	XP_002802691.1
Bos taurus (cattle)	CCDC80	NP_001092452.1
Gallus gallus (chicken)	CCDC80	NP_989762.1

Gene Ontology
Bibliography

Related articles in PubMed

Multiple roles of Equarin during lens development.
Song X, Tanaka H, Ohta K
Development, growth & differentiation56(3)199-205(2014 Apr)

Equarin is involved in cell adhesion by means of heparan sulfate proteoglycan during lens development.
Song X, Sato Y, Sekiguchi K, Tanaka H, Ohta K
Developmental dynamics : an official publication of the American Association of Anatomists242(1)23-9(2013 Jan)

Equarin is involved as an FGF signaling modulator in chick lens differentiation.
Song X, Sato Y, Felemban A, Ito A, Hossain M, Ochiai H, Yamamoto T, Sekiguchi K, Tanaka H, Ohta K
Developmental biology368(1)109-17(2012 Aug)

A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells.
Jarrin M, Pandit T, Gunhaga L
Molecular biology of the cell23(16)3266-74(2012 Aug)

Equarin, a novel soluble molecule expressed with polarity at chick embryonic lens equator, is involved in eye formation.
Mu H, Ohta K, Kuriyama S, Shimada N, Tanihara H, Yasuda K, Tanaka H
Mechanisms of development120(2)143-55(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

As lens development proceeds, Equarin is strongly expressed in the lens equatorial region with a high-dorsal-to-low-ventral gradient.
Title: Multiple roles of Equarin during lens development.

Equarin is involved in cell adhesion during fiber differentiation and development.
Title: Equarin is involved in cell adhesion by means of heparan sulfate proteoglycan during lens development.

Data show that endogenous Equarin is required for chick lens cell differentiation.
Title: Equarin is involved as an FGF signaling modulator in chick lens differentiation.

Equarin gene expression is regulated by a balance of FGF and BMP signals in lens cells of the developing eye.
Title: A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells.

The following CCDC80 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCDC80 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27088	NM_204431.1 Latest version!	Gallus gallus coiled-coil domain containing 80 (CCDC80), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$510.30 $729.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCDC80 ( NM_204431.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_989762.1 Gallus gallus coiled-coil domain containing 80 (CCDC80), mRNA.

Price & Availability↑

CloneID	OGa27088
Clone ID Related Accession (Same CDS sequence)	NM_204431.1
Accession Version	NM_204431.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2877bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Gallus gallus(chicken)
Product	coiled-coil domain-containing protein 80 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB086824.1. ##Evidence-Data-START## Transcript exon combination :: AB086824.1 [ECO:0000332] ##Evidence-Data-END##

ATGAACTGGA TGCCAGCTCT CAGCTTAGCC CTGCTGTGGA CAGCATGGCT AGTTTGTGGC 
TCGGAGAAGA CAGGGAGGTT AGCAGAGAGA GGGAGCCATG GAGTTAGGAA AGTGCCTCAG 
TCTCACAGGG CTCCAAGCAG CCTCCTGAGA AGGTCTGGAG CATCCCTAAA GAATCTGAGC 
CCCAGTCCCC AACACCCGGT CACCAAGAGA GATTCTTCAG TACCTCCAAA GGCACCTGCC 
AACCTCCTGA AAGAGGAATC ACGTTCCCAG CCCAGGAGCG TAGGCACCAG AACAAGGCGG 
TTACAGAGAC TCACAGCTGC AGCCAAATAC TCCAAGTCTG AGATGATTAA GGATGAAGGG 
ATATCTACCG CCTCACAGTC ACGAGCAGTA CGCTTCCCTT CAGGGTCAAG CTCCCCCAAT 
GTCTTGGCCA GCTTTGCTGG GAAAAATCGG GTGTGGGTCA TTTCTGCCCC CCATGCCTCA 
GAGGGCTACT ACCGGCTCAT GATGAGCCTG CTGAAAAATG ATGTTTACTG TGAACTGGCT 
GAGAGACACA TCCAGCAGAT TGTGTTGTTC CATGAAGAAG GGGAAGAAGG AGGGAAAGTC 
AGAAGGATAA CCAATGAAGG AAAAATCTTG GAACAGCCAC TGGATCCTGC TCTCATCCCT 
AAGCTCATGA GCTTTCTGAA ACTAGAAAAG GGGAAATTTG GCATGGTGCT GCTGAAGAAA 
ACTCTACAGG TGGAGGAAAG GTACCCTTAT CCCGTAAGGC TAGAGGCCAT GTATGAGGTC 
ATTGATCAGA ACCCCATCAG AAAAATTGAG AAGATGAGAC AGAAGGGTTT CATACAGACT 
TGCAAAGCAG CTGGGGTGGA GGGACAGGTG GTTGAAGATG ACAATAATGG GGGTAGCACC 
CAATCTATCC CTGGTGGTGG ACATGTCCAA GTGTCAGCAG GAGGGAGGAA GGAGGAACCA 
AGGAGGAGCA GCAACCAGCC AACAAGGACC AAAACAGTGA GAAAACCGAT GACAACCACT 
GTGGCTACTC CTCTGCCTAC AGTAAGGACC ACTACCCTCC CTACCACCAC CACAGCCACC 
CGGGCCACCA CCCGCACAGT GACAACAGCA AGCAGGCCTA CAACAACAAC TACACCCCTC 
CCCACCACGC AGAGGACATG GACCACAAAG TCACATACCA CCACAGAGTA CCATAGGCTG 
CCAGCATCTC CTGAGGTCAC CACACCGCGA GTCATGGCCT CTGAGGATTT CTATTCTCCT 
GTGTGGAAGG CAAATCGCAG GGACCGGCAG CGAGGCCACC CAGAGAAACA CCTGGCAGCC 
ACACGGAAAC CAAGCAAAGG TGGCCGCTAT GAGAGCTTCA CAGAAGTCCC AACAGCCCCC 
TCAGTGCACT ACACAAAGGC AAGCATGAGT AGGTTTAAAG ATAATCGAAC AGACAGGAAG 
GACTATAACC ACAGGGACCT GAATGTCACG CCAGGGCAAC ACAAACCGAC TAAGACTAAA 
CCACCAAAAA AGAAGACACA AGAGAAGATA CTGAGTAATG AATATGAAGA TAAATATGAC 
CCAAGTAAGC CTGCTAGTCC CCATTTAGAG GAAGAGATTG CAGTGGGAAG TATTCCCCCA 
AAGAAAGGAA AAGAATCAAA GAAGCATGAG CGAATGGATA AACCTGAGAA GAAAAAGAAG 
AAGGACAGAC CTGACAAGCT GCACAAGAGT GAGAAGCAGT CCAAGAAGGA CAAAGCTGAG 
AAAAAGAGCA AGCAGGATAA AGACCGTAGC AAAAAAAACA AGAAGGGGAG CAGAACAGAG 
AATGAGGATT TCCCCAAGCC CAACAAGAAG CCTTTCTTAC AGCCTCCCAG GAAATCGGTG 
GCCAACCTCC TGGACTATTT TGAAGGCAAA AGGCGGCTCA TTCTGATTAC AACCCCCAAG 
GCGGACAACA CCATGTATGT TCAGCAGCGA GACGAGTATC TGGAGAGCTT CTGCAAGATG 
GCAACAAGGA AAATCTCAGT CATTACAATT TTTGGCACCA TGAACAACAG CAGCATGAAA 
ATTGACCACT TCCAGCTAGA TAACGAAAAG CCCATGAAAG TGATAGAGGA TGAAGATCTT 
GTGGATCAGC AGCTCATCAG TGAGCTGAGG AAAGAGTATG GGATGACCTA CAATGACTTC 
TTCATGGTGC TGACGGACAC TGACATGAAG GTCAAGCAAT ACTATGAAGT ACCTATAGCA 
ATGAAGTCTG TGTTTGATTT GATCGACACC TTCCAGTCAC GAATTAAAGA CATGGAAAGA 
CAGAAAAAAG AGGGCATTGT CTGCAAAGAA GATAAAAAGC AATCCCTTGA GAGCTTCTTA 
TCCAGGTTCC GATGGAGAAG GCGGCTAGTG GTGATCTCTG CTCCCAGTGA TGAGGACTGG 
GCTTATTCCC AGCAGCTTGC TGCTCTCAGT GGACAAGCCT GTAATTTTGG TCTGCGCCAT 
ATAACTATCC TCAAGTTGCT AGGAGTTGGA GAAGATATTG GTGGTGTCTT AGAGTTGTAT 
CCAATTAATG GAAGTGCTAC TGTAGACCGA GAAGATATCC CAGCTAACTT GGTGAAAGAC 
ATTCGAAATT ATTTCCAAAT TAGCCCAGAG TATTTCTCCA TGCTTCTAGT TGGGAAAGAT 
GGAAACGTCA AATCCTGGTA TCCTTCTCCA ATGTGGTCTA TGGCAATTGT GTATGATCTG 
ATTGATTCCA TGCAGCTTCG GCGACAGGAA ATGACAATTC AGCAATCGCT CGGCATGCAA 
TGCCCAGAAG ATGAGTATGG TGGGTATGGT TACCATAGCT ATCACCAGGG ATACCAGGAA 
GGTTACCAGG ATGACTACCG CCACCATGGA AGTTACCACC ATGGATATCC ATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_989762.1
CDS	633..3509
Translation	MNWMPALSLALLWTAWLVCGSEKTGRLAERGSHGVRKVPQSHRAPSSLLRRSGASLKNLSPSPQHPVTKRDSSVPPKAPANLLKEESRSQPRSVGTRTRRLQRLTAAAKYSKSEMIKDEGISTASQSRAVRFPSGSSSPNVLASFAGKNRVWVISAPHASEGYYRLMMSLLKNDVYCELAERHIQQIVLFHEEGEEGGKVRRITNEGKILEQPLDPALIPKLMSFLKLEKGKFGMVLLKKTLQVEERYPYPVRLEAMYEVIDQNPIRKIEKMRQKGFIQTCKAAGVEGQVVEDDNNGGSTQSIPGGGHVQVSAGGRKEEPRRSSNQPTRTKTVRKPMTTTVATPLPTVRTTTLPTTTTATRATTRTVTTASRPTTTTTPLPTTQRTWTTKSHTTTEYHRLPASPEVTTPRVMASEDFYSPVWKANRRDRQRGHPEKHLAATRKPSKGGRYESFTEVPTAPSVHYTKASMSRFKDNRTDRKDYNHRDLNVTPGQHKPTKTKPPKKKTQEKILSNEYEDKYDPSKPASPHLEEEIAVGSIPPKKGKESKKHERMDKPEKKKKKDRPDKLHKSEKQSKKDKAEKKSKQDKDRSKKNKKGSRTENEDFPKPNKKPFLQPPRKSVANLLDYFEGKRRLILITTPKADNTMYVQQRDEYLESFCKMATRKISVITIFGTMNNSSMKIDHFQLDNEKPMKVIEDEDLVDQQLISELRKEYGMTYNDFFMVLTDTDMKVKQYYEVPIAMKSVFDLIDTFQSRIKDMERQKKEGIVCKEDKKQSLESFLSRFRWRRRLVVISAPSDEDWAYSQQLAALSGQACNFGLRHITILKLLGVGEDIGGVLELYPINGSATVDREDIPANLVKDIRNYFQISPEYFSMLLVGKDGNVKSWYPSPMWSMAIVYDLIDSMQLRRQEMTIQQSLGMQCPEDEYGGYGYHSYHQGYQEGYQDDYRHHGSYHHGYPY

Target ORF information:

RefSeq Version	NM_204431.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus coiled-coil domain containing 80 (CCDC80), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_204431.1

ORF Insert Sequence:

ATGAACTGGA TGCCAGCTCT CAGCTTAGCC CTGCTGTGGA CAGCATGGCT AGTTTGTGGC 
TCGGAGAAGA CAGGGAGGTT AGCAGAGAGA GGGAGCCATG GAGTTAGGAA AGTGCCTCAG 
TCTCACAGGG CTCCAAGCAG CCTCCTGAGA AGGTCTGGAG CATCCCTAAA GAATCTGAGC 
CCCAGTCCCC AACACCCGGT CACCAAGAGA GATTCTTCAG TACCTCCAAA GGCACCTGCC 
AACCTCCTGA AAGAGGAATC ACGTTCCCAG CCCAGGAGCG TAGGCACCAG AACAAGGCGG 
TTACAGAGAC TCACAGCTGC AGCCAAATAC TCCAAGTCTG AGATGATTAA GGATGAAGGG 
ATATCTACCG CCTCACAGTC ACGAGCAGTA CGCTTCCCTT CAGGGTCAAG CTCCCCCAAT 
GTCTTGGCCA GCTTTGCTGG GAAAAATCGG GTGTGGGTCA TTTCTGCCCC CCATGCCTCA 
GAGGGCTACT ACCGGCTCAT GATGAGCCTG CTGAAAAATG ATGTTTACTG TGAACTGGCT 
GAGAGACACA TCCAGCAGAT TGTGTTGTTC CATGAAGAAG GGGAAGAAGG AGGGAAAGTC 
AGAAGGATAA CCAATGAAGG AAAAATCTTG GAACAGCCAC TGGATCCTGC TCTCATCCCT 
AAGCTCATGA GCTTTCTGAA ACTAGAAAAG GGGAAATTTG GCATGGTGCT GCTGAAGAAA 
ACTCTACAGG TGGAGGAAAG GTACCCTTAT CCCGTAAGGC TAGAGGCCAT GTATGAGGTC 
ATTGATCAGA ACCCCATCAG AAAAATTGAG AAGATGAGAC AGAAGGGTTT CATACAGACT 
TGCAAAGCAG CTGGGGTGGA GGGACAGGTG GTTGAAGATG ACAATAATGG GGGTAGCACC 
CAATCTATCC CTGGTGGTGG ACATGTCCAA GTGTCAGCAG GAGGGAGGAA GGAGGAACCA 
AGGAGGAGCA GCAACCAGCC AACAAGGACC AAAACAGTGA GAAAACCGAT GACAACCACT 
GTGGCTACTC CTCTGCCTAC AGTAAGGACC ACTACCCTCC CTACCACCAC CACAGCCACC 
CGGGCCACCA CCCGCACAGT GACAACAGCA AGCAGGCCTA CAACAACAAC TACACCCCTC 
CCCACCACGC AGAGGACATG GACCACAAAG TCACATACCA CCACAGAGTA CCATAGGCTG 
CCAGCATCTC CTGAGGTCAC CACACCGCGA GTCATGGCCT CTGAGGATTT CTATTCTCCT 
GTGTGGAAGG CAAATCGCAG GGACCGGCAG CGAGGCCACC CAGAGAAACA CCTGGCAGCC 
ACACGGAAAC CAAGCAAAGG TGGCCGCTAT GAGAGCTTCA CAGAAGTCCC AACAGCCCCC 
TCAGTGCACT ACACAAAGGC AAGCATGAGT AGGTTTAAAG ATAATCGAAC AGACAGGAAG 
GACTATAACC ACAGGGACCT GAATGTCACG CCAGGGCAAC ACAAACCGAC TAAGACTAAA 
CCACCAAAAA AGAAGACACA AGAGAAGATA CTGAGTAATG AATATGAAGA TAAATATGAC 
CCAAGTAAGC CTGCTAGTCC CCATTTAGAG GAAGAGATTG CAGTGGGAAG TATTCCCCCA 
AAGAAAGGAA AAGAATCAAA GAAGCATGAG CGAATGGATA AACCTGAGAA GAAAAAGAAG 
AAGGACAGAC CTGACAAGCT GCACAAGAGT GAGAAGCAGT CCAAGAAGGA CAAAGCTGAG 
AAAAAGAGCA AGCAGGATAA AGACCGTAGC AAAAAAAACA AGAAGGGGAG CAGAACAGAG 
AATGAGGATT TCCCCAAGCC CAACAAGAAG CCTTTCTTAC AGCCTCCCAG GAAATCGGTG 
GCCAACCTCC TGGACTATTT TGAAGGCAAA AGGCGGCTCA TTCTGATTAC AACCCCCAAG 
GCGGACAACA CCATGTATGT TCAGCAGCGA GACGAGTATC TGGAGAGCTT CTGCAAGATG 
GCAACAAGGA AAATCTCAGT CATTACAATT TTTGGCACCA TGAACAACAG CAGCATGAAA 
ATTGACCACT TCCAGCTAGA TAACGAAAAG CCCATGAAAG TGATAGAGGA TGAAGATCTT 
GTGGATCAGC AGCTCATCAG TGAGCTGAGG AAAGAGTATG GGATGACCTA CAATGACTTC 
TTCATGGTGC TGACGGACAC TGACATGAAG GTCAAGCAAT ACTATGAAGT ACCTATAGCA 
ATGAAGTCTG TGTTTGATTT GATCGACACC TTCCAGTCAC GAATTAAAGA CATGGAAAGA 
CAGAAAAAAG AGGGCATTGT CTGCAAAGAA GATAAAAAGC AATCCCTTGA GAGCTTCTTA 
TCCAGGTTCC GATGGAGAAG GCGGCTAGTG GTGATCTCTG CTCCCAGTGA TGAGGACTGG 
GCTTATTCCC AGCAGCTTGC TGCTCTCAGT GGACAAGCCT GTAATTTTGG TCTGCGCCAT 
ATAACTATCC TCAAGTTGCT AGGAGTTGGA GAAGATATTG GTGGTGTCTT AGAGTTGTAT 
CCAATTAATG GAAGTGCTAC TGTAGACCGA GAAGATATCC CAGCTAACTT GGTGAAAGAC 
ATTCGAAATT ATTTCCAAAT TAGCCCAGAG TATTTCTCCA TGCTTCTAGT TGGGAAAGAT 
GGAAACGTCA AATCCTGGTA TCCTTCTCCA ATGTGGTCTA TGGCAATTGT GTATGATCTG 
ATTGATTCCA TGCAGCTTCG GCGACAGGAA ATGACAATTC AGCAATCGCT CGGCATGCAA 
TGCCCAGAAG ATGAGTATGG TGGGTATGGT TACCATAGCT ATCACCAGGG ATACCAGGAA 
GGTTACCAGG ATGACTACCG CCACCATGGA AGTTACCACC ATGGATATCC ATACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Multiple roles of Equarin during lens development.
Development, growth & differentiation56(3)199-205(2014 Apr)
Song X,Tanaka H,Ohta K

Equarin is involved in cell adhesion by means of heparan sulfate proteoglycan during lens development.
Developmental dynamics : an official publication of the American Association of Anatomists242(1)23-9(2013 Jan)
Song X,Sato Y,Sekiguchi K,Tanaka H,Ohta K

Equarin is involved as an FGF signaling modulator in chick lens differentiation.
Developmental biology368(1)109-17(2012 Aug)
Song X,Sato Y,Felemban A,Ito A,Hossain M,Ochiai H,Yamamoto T,Sekiguchi K,Tanaka H,Ohta K

A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells.
Molecular biology of the cell23(16)3266-74(2012 Aug)
Jarrin M,Pandit T,Gunhaga L

Equarin, a novel soluble molecule expressed with polarity at chick embryonic lens equator, is involved in eye formation.
Mechanisms of development120(2)143-55(2003 Feb)
Mu H,Ohta K,Kuriyama S,Shimada N,Tanihara H,Yasuda K,Tanaka H