Debcl cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Debcl
Entrez Gene ID	53585
Full Name	Death executioner Bcl-2
Synonyms	BG1,BOK,Bcl-2,Bok,Bok(Debcl),CG12397,CG33134,DBok,DEBCL,Dbok,Debcl/Drob-1/dBorg-1/dBok,Debcl/dBorg-1/dBok/Drob-1,Debcl/dBorg-1/dRob-1,Dmel\CG33134,Drob-1,Drob-1/Debcl/dBORG-1,Drob-1/Debcl/dBorg-1/DBok,Drob-1/Debcl/dBorg-1/dBok,bcl-2,borg1/debcl,dBOK,dBORG-1/DROB-1/DEBCL/dBOK,dBok,dBorg-1,dBorg01,dBorg1,dBrog-1,dbok,dbok/debcl,dborg1,debc1,debcl,debcl/Borg1,debok,drob-1
General protein information	Preferred Names Death executioner Bcl-2 Names CG33134 gene product from transcript CG33134-RA Bcl-2 CG33134-PA Debcl-PA death executioner Bcl-2 death executioner Bcl-2 homologue death inducing Bcl-2-like protein deborg
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 42B2-42C1

mRNA and Protein(s)

mRNA	Protein	Name
NM_176098.3	NP_788278.1	death executioner Bcl-2

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	debcl	NP_788278.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011552	XP_309956.4

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Debcl modulates Drp1 mitochondrial localization during apoptosis.
Title: The Drosophila retinoblastoma protein, Rbf1, induces a Debcl- and Drp1-dependent mitochondrial apoptosis.

Slimb targets Bax and Debcl to the proteasome.
Title: The drosophila Bcl-2 family protein Debcl is targeted to the proteasome by the ?-TrCP homologue slimb.

dNF-Y regulates debcl gene expression.
Title: dNF-YB plays dual roles in cell death and cell differentiation during Drosophila eye development.

Although gross development and lifespans were unaffected, we found that Debcl was required for pruning cells in the developing central nervous system.
Title: The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death.

Developmental programmed cell death regulation in the fly does not rely upon the Bcl-2 proteins.
Title: Drosophila Bcl-2 proteins participate in stress-induced apoptosis, but are not required for normal development.

The following Debcl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Debcl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa11534	NM_176098.3 Latest version!	Drosophila melanogaster death executioner Bcl-2 (Debcl), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Debcl ( NM_176098.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_788278.1 Drosophila melanogaster death executioner Bcl-2 (Debcl), mRNA.

Price & Availability↑

CloneID	OFa11534
Clone ID Related Accession (Same CDS sequence)	NM_176098.3
Accession Version	NM_176098.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	death executioner Bcl-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_176098.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCTCCCA CCACCAGTCC GCCACCCAAG CTGGCCAAGT TCAAGTCCTC GTCGCTGGAC 
CACGAGATCT ACACGGCCAA TCGCCGCGGC ACCATTGCCA CGGCCTCCAG CGACTGGAAG 
GCGCTCCGCG GAGGCGTCGG TGGAGGAGCA GGAGGACCCG GTAGCGTACC CAATCCCTCT 
AACGGACGCT CCCTTCACGC CGGCGGACCC ATGACACGGG CCGCCTCCAC ATCCTCGCTG 
GCTAGCAGTA CGCGCACGAT GACTAACTAC CAGGAGTACA AAATGGATAT CATCAACCAG 
GGGAAATGTC TGTGTGGTCA GTACATCAGA GCGCGGCTGC GACGGGCAGG AGTCCTCAAC 
CGGAAGGTGA CACAGCGTTT GCGCAACATC CTGGACCCCG GCTCCTCGCA CGTGGTCTAT 
GAAGTTTTCC CGGCACTGAA CAGCATGGGC GAGGAACTGG AGCGGATGCA CCCGCGGGTG 
TACACAAACA TATCGCGACA GCTGTCGAGG GCCCCGTTTG GCGAGCTGGA GGACAGCGAC 
ATGGCGCCCA TGTTGCTCAA CCTAGTTGCC AAGGATCTTT TTCGCTCCAG CATCACCTGG 
GGCAAGATAA TCTCGATATT TGCCGTATGC GGCGGCTTTG CCATAGACTG CGTGCGCCAG 
GGACATTTCG ACTACCTACA GTGCCTGATT GACGGTCTGG CTGAGATCAT AGAGGACGAC 
CTGGTCTACT GGCTGATCGA CAACGGCGGA TGGTTGGGCC TGTCGCGGCA CATCCGACCC 
CGGGTCGGCG AATTTACGTT CTTGGGATGG TTGACGCTGT TCGTGACTAT CTCTGCAGGC 
GCATATATGG TCTCAAACGT GTGTCGGCGC ATTGGAGGTC AACTGTATTC GCTGCTGTTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_788278.1
CDS	626..1528
Translation	MAPTTSPPPKLAKFKSSSLDHEIYTANRRGTIATASSDWKALRGGVGGGAGGPGSVPNPSNGRSLHAGGPMTRAASTSSLASSTRTMTNYQEYKMDIINQGKCLCGQYIRARLRRAGVLNRKVTQRLRNILDPGSSHVVYEVFPALNSMGEELERMHPRVYTNISRQLSRAPFGELEDSDMAPMLLNLVAKDLFRSSITWGKIISIFAVCGGFAIDCVRQGHFDYLQCLIDGLAEIIEDDLVYWLIDNGGWLGLSRHIRPRVGEFTFLGWLTLFVTISAGAYMVSNVCRRIGGQLYSLLF

Target ORF information:

RefSeq Version	NM_176098.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster death executioner Bcl-2 (Debcl), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176098.3

ORF Insert Sequence:

ATGGCTCCCA CCACCAGTCC GCCACCCAAG CTGGCCAAGT TCAAGTCCTC GTCGCTGGAC 
CACGAGATCT ACACGGCCAA TCGCCGCGGC ACCATTGCCA CGGCCTCCAG CGACTGGAAG 
GCGCTCCGCG GAGGCGTCGG TGGAGGAGCA GGAGGACCCG GTAGCGTACC CAATCCCTCT 
AACGGACGCT CCCTTCACGC CGGCGGACCC ATGACACGGG CCGCCTCCAC ATCCTCGCTG 
GCTAGCAGTA CGCGCACGAT GACTAACTAC CAGGAGTACA AAATGGATAT CATCAACCAG 
GGGAAATGTC TGTGTGGTCA GTACATCAGA GCGCGGCTGC GACGGGCAGG AGTCCTCAAC 
CGGAAGGTGA CACAGCGTTT GCGCAACATC CTGGACCCCG GCTCCTCGCA CGTGGTCTAT 
GAAGTTTTCC CGGCACTGAA CAGCATGGGC GAGGAACTGG AGCGGATGCA CCCGCGGGTG 
TACACAAACA TATCGCGACA GCTGTCGAGG GCCCCGTTTG GCGAGCTGGA GGACAGCGAC 
ATGGCGCCCA TGTTGCTCAA CCTAGTTGCC AAGGATCTTT TTCGCTCCAG CATCACCTGG 
GGCAAGATAA TCTCGATATT TGCCGTATGC GGCGGCTTTG CCATAGACTG CGTGCGCCAG 
GGACATTTCG ACTACCTACA GTGCCTGATT GACGGTCTGG CTGAGATCAT AGAGGACGAC 
CTGGTCTACT GGCTGATCGA CAACGGCGGA TGGTTGGGCC TGTCGCGGCA CATCCGACCC 
CGGGTCGGCG AATTTACGTT CTTGGGATGG TTGACGCTGT TCGTGACTAT CTCTGCAGGC 
GCATATATGG TCTCAAACGT GTGTCGGCGC ATTGGAGGTC AACTGTATTC GCTGCTGTTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Debcl cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報