IKKbeta cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	IKKbeta
Entrez Gene ID	44432
Full Name	I-kappaB kinase beta
Synonyms	CG4201,DIK,DLAK,DmIKK,DmIKKBeta,DmIKKb,DmIKKbeta,DmIkkbeta,Dmel\CG4201,Dmikkb,Dmikkbeta,IK,IKK,IKK-beta,IKKB,IKKb,IRD-5,IRD5,Ik,Ikkb,Ikkbeta,Ird-5,Ird5,LRK,Lak,anon-89Bd,dIKK,dIKK-beta,dIKKbeta,dLak,dmIKKbeta,ikk,ird,ird-5,ird5,ird5/DmIkk[beta],ird[5]
General protein information	Preferred Names I-kappaB kinase beta Names CG4201 gene product from transcript CG4201-RB CG4201-PB IKK-like protein IKKbeta-PB LPS-responsive kinase LPS-responsive-kinase cactus kinase immune response deficient 5 immune response-deficient 5 lipopolysaccharide activated kinase mmune response deficient 5
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 89B1-89B1

mRNA and Protein(s)

mRNA	Protein	Name
NM_080012.4	NP_524751.3	I-kappaB kinase beta

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	ird5	NP_524751.3
Anopheles gambiae (African malaria mosquito)	IKK1	XP_553095.3

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following IKKbeta gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IKKbeta cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa06845	NM_080012.4 Latest version!	Drosophila melanogaster I-kappaB kinase beta (IKKbeta), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IKKbeta ( NM_080012.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524751.3 Drosophila melanogaster I-kappaB kinase beta (IKKbeta), mRNA.

Price & Availability↑

CloneID	OFa06845
Clone ID Related Accession (Same CDS sequence)	NM_080012.4
Accession Version	NM_080012.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	I-kappaB kinase beta
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jan 16, 2013 this sequence version replaced NM_080012.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGCACTCTT TTGGGAACTG GGAGCGGTGC CGGAATCTGG GAGAGGGCGG ATTCGGCCTA 
GTGATCCATT GGCGAAACCG AACAACGGGC CGTGAAATTG CCACCAAGCA CATAAAGGAG 
ATGGGGGCCC TGAGTGCCGA TCAGCAAGTC AAGCTCAGCG AGCGTTGGAA CAAGGAGCTG 
AACTGGTCTC GTCAGTTTAA AAACTTTCCC CATATTGTGG CTGGCGTGGA CATCGAGGAT 
CCGGACTTTT TGGAGTACCT GAATGGCATG TTTAGTGCCA AGTTGCCTGT TATTGTGCTG 
GAATACTGTA ACGGTGGAGA CGTGAGGAAG CGTCTGCAGA GCCCGGAGAA TGCTAATGGT 
CTGACGGAGT TCGAGGTGCG GCAGATACTG GGAGCCCTAC GTAAGGCCCT ACATTTTCTG 
CACTCGCAGT GTGGGATTTG CCACCGCGAT TTGAAGCCGG ACAATATAGT AATCCAACGT 
GGAGTTGATG GCAAAAAAAT CTATAAGCTA ACCGATTTTG GACTCGCCCG AGGAACTCCC 
GACCAGACCA TGGTGCAGAG CGTGGTGGGC ACCCGACATT ACTATGCCCC AGAAGTGGTG 
GAAAATGGTT TTTACAACTC GACCGTGGAT TTATGGTCCT TCGGAGTAAT TGCCTATGAG 
CTGGTCACTG GTGAGCTGCC CTTCATCCCC CATCAAACCC TTAAAAACAT TATACTCAAT 
CTGATAAAAA AGCCCGCCAA ATGCATTGCT ATCACAGAGG ATCCGGAGGA TAACACTCGT 
TTCGTGAATC AGTTTGAACT GCCACAGACG CACCATCTGT CGCGGCCCTG GGCTGCTCAG 
TTCACCAAAT GGCTGGCAAG CCCGTTAAAC TCAAACTACA AGGAACGCGG TCAACTAGCA 
GCTAATAACG TTCCAGTCGT CTTCGCTGAC CTGGACAAAA TACTCAATAT GAATGTGCTA 
ACTATTTTTG CTGTTAACAA CTGCGAACGA CTTGAGTATG CGGTCTCTGC GGAGATGACT 
ATGAAGGATC TAATTGCGTT GATTGTCCTG GACACTGGAA TGGACGAAAA GGAACTGTAC 
TTCGTGCTGC CCACTTCCCA TCCGCACAAA ACGATTACGC CTAAAAGTAC GCCCTTGCAG 
CTGTATGTGG AGGAGTGGAG TGACACAAGC AAAGATTCAC GAAAGTGGAC TAAGCGCAGC 
AATCCACCTG TGATGTTGTA CATCTTTCAG GTCAAGAAAG AGTGTGACTA CAAAATACCT 
GAACCCATTC TATCAATTCT TTCTCGAAAG TTTATCGCTA ACAAATTTAA GACGAAGGAA 
AGATGGCTGC AAAAACGTGT TGTCTTGGAT ATGCTCTACG TGCTAACCAA AGAGCAAGCA 
AGATACGAAA TGCTCGTGTC AGGAATAAAC GAGCGAGCGT TGTCGTTGGA AGACGAAATG 
ATGGAAAACT CGTTTATAGA CAGCATCGAT AAGCAGCGTA TCATAATCTC CTTTGCCTAT 
GATCAGCTAA CAAGCTTGCT AAAAGAAGCC CAAGCAAAGA TTCCGTCCCG CCAGCTTATC 
AGCAGTGCAC AGTGGGAGAA GCTTAACCGC AATTATAATT TCATTATACA AAGCGCAAAA 
TCAATTAGGT CTTTCTTGGA AGCCTGCTTG CGGGAAGCCA AGGACATGGT TAAAACCACC 
AATCAACTAC GGAAAGAAGT TTGCGAGAAA GACCTATTCG ATTGCGCTCG ATTTTATAAG 
AAATATCTCT GCAATGGTGC GATAATTTCG CCATCAGAGT TAAATAATGA CGCCGAGGAA 
TTCGCAAAAT CTCGTTTCAA GTTATATAAC GAGGGCGAGG CTAGACATCT GCCCAAGTCT 
ATCGATCACA TGCATTACTT ATATTTTAAG ACCAAGGAGT CCATCCCGGT CCTTCTACAA 
CAATTTTGCG ACATCAAGAA GGAGATATTT CAGATTAACT TGCAGATGTT GATGTCAGCC 
TCAAGCACAC CACCTCCGAA GCTTGAGCTA AGCGCAGCGA TGGACCGCCT AGCTATAAGC 
TCTGGCTCAC CCAGCTCGGA TCCATTTGAC TCTCTACGCA CGATAAACGC TATCGAAGAG 
GCAGAAAGGA TTAACAACAT ACTTGTTAAT GAAATGAAAA TTGATCACTA TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524751.3
CDS	102..2255
Translation	MHSFGNWERCRNLGEGGFGLVIHWRNRTTGREIATKHIKEMGALSADQQVKLSERWNKELNWSRQFKNFPHIVAGVDIEDPDFLEYLNGMFSAKLPVIVLEYCNGGDVRKRLQSPENANGLTEFEVRQILGALRKALHFLHSQCGICHRDLKPDNIVIQRGVDGKKIYKLTDFGLARGTPDQTMVQSVVGTRHYYAPEVVENGFYNSTVDLWSFGVIAYELVTGELPFIPHQTLKNIILNLIKKPAKCIAITEDPEDNTRFVNQFELPQTHHLSRPWAAQFTKWLASPLNSNYKERGQLAANNVPVVFADLDKILNMNVLTIFAVNNCERLEYAVSAEMTMKDLIALIVLDTGMDEKELYFVLPTSHPHKTITPKSTPLQLYVEEWSDTSKDSRKWTKRSNPPVMLYIFQVKKECDYKIPEPILSILSRKFIANKFKTKERWLQKRVVLDMLYVLTKEQARYEMLVSGINERALSLEDEMMENSFIDSIDKQRIIISFAYDQLTSLLKEAQAKIPSRQLISSAQWEKLNRNYNFIIQSAKSIRSFLEACLREAKDMVKTTNQLRKEVCEKDLFDCARFYKKYLCNGAIISPSELNNDAEEFAKSRFKLYNEGEARHLPKSIDHMHYLYFKTKESIPVLLQQFCDIKKEIFQINLQMLMSASSTPPPKLELSAAMDRLAISSGSPSSDPFDSLRTINAIEEAERINNILVNEMKIDHY

Target ORF information:

RefSeq Version	NM_080012.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster I-kappaB kinase beta (IKKbeta), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_080012.4

ORF Insert Sequence:

ATGCACTCTT TTGGGAACTG GGAGCGGTGC CGGAATCTGG GAGAGGGCGG ATTCGGCCTA 
GTGATCCATT GGCGAAACCG AACAACGGGC CGTGAAATTG CCACCAAGCA CATAAAGGAG 
ATGGGGGCCC TGAGTGCCGA TCAGCAAGTC AAGCTCAGCG AGCGTTGGAA CAAGGAGCTG 
AACTGGTCTC GTCAGTTTAA AAACTTTCCC CATATTGTGG CTGGCGTGGA CATCGAGGAT 
CCGGACTTTT TGGAGTACCT GAATGGCATG TTTAGTGCCA AGTTGCCTGT TATTGTGCTG 
GAATACTGTA ACGGTGGAGA CGTGAGGAAG CGTCTGCAGA GCCCGGAGAA TGCTAATGGT 
CTGACGGAGT TCGAGGTGCG GCAGATACTG GGAGCCCTAC GTAAGGCCCT ACATTTTCTG 
CACTCGCAGT GTGGGATTTG CCACCGCGAT TTGAAGCCGG ACAATATAGT AATCCAACGT 
GGAGTTGATG GCAAAAAAAT CTATAAGCTA ACCGATTTTG GACTCGCCCG AGGAACTCCC 
GACCAGACCA TGGTGCAGAG CGTGGTGGGC ACCCGACATT ACTATGCCCC AGAAGTGGTG 
GAAAATGGTT TTTACAACTC GACCGTGGAT TTATGGTCCT TCGGAGTAAT TGCCTATGAG 
CTGGTCACTG GTGAGCTGCC CTTCATCCCC CATCAAACCC TTAAAAACAT TATACTCAAT 
CTGATAAAAA AGCCCGCCAA ATGCATTGCT ATCACAGAGG ATCCGGAGGA TAACACTCGT 
TTCGTGAATC AGTTTGAACT GCCACAGACG CACCATCTGT CGCGGCCCTG GGCTGCTCAG 
TTCACCAAAT GGCTGGCAAG CCCGTTAAAC TCAAACTACA AGGAACGCGG TCAACTAGCA 
GCTAATAACG TTCCAGTCGT CTTCGCTGAC CTGGACAAAA TACTCAATAT GAATGTGCTA 
ACTATTTTTG CTGTTAACAA CTGCGAACGA CTTGAGTATG CGGTCTCTGC GGAGATGACT 
ATGAAGGATC TAATTGCGTT GATTGTCCTG GACACTGGAA TGGACGAAAA GGAACTGTAC 
TTCGTGCTGC CCACTTCCCA TCCGCACAAA ACGATTACGC CTAAAAGTAC GCCCTTGCAG 
CTGTATGTGG AGGAGTGGAG TGACACAAGC AAAGATTCAC GAAAGTGGAC TAAGCGCAGC 
AATCCACCTG TGATGTTGTA CATCTTTCAG GTCAAGAAAG AGTGTGACTA CAAAATACCT 
GAACCCATTC TATCAATTCT TTCTCGAAAG TTTATCGCTA ACAAATTTAA GACGAAGGAA 
AGATGGCTGC AAAAACGTGT TGTCTTGGAT ATGCTCTACG TGCTAACCAA AGAGCAAGCA 
AGATACGAAA TGCTCGTGTC AGGAATAAAC GAGCGAGCGT TGTCGTTGGA AGACGAAATG 
ATGGAAAACT CGTTTATAGA CAGCATCGAT AAGCAGCGTA TCATAATCTC CTTTGCCTAT 
GATCAGCTAA CAAGCTTGCT AAAAGAAGCC CAAGCAAAGA TTCCGTCCCG CCAGCTTATC 
AGCAGTGCAC AGTGGGAGAA GCTTAACCGC AATTATAATT TCATTATACA AAGCGCAAAA 
TCAATTAGGT CTTTCTTGGA AGCCTGCTTG CGGGAAGCCA AGGACATGGT TAAAACCACC 
AATCAACTAC GGAAAGAAGT TTGCGAGAAA GACCTATTCG ATTGCGCTCG ATTTTATAAG 
AAATATCTCT GCAATGGTGC GATAATTTCG CCATCAGAGT TAAATAATGA CGCCGAGGAA 
TTCGCAAAAT CTCGTTTCAA GTTATATAAC GAGGGCGAGG CTAGACATCT GCCCAAGTCT 
ATCGATCACA TGCATTACTT ATATTTTAAG ACCAAGGAGT CCATCCCGGT CCTTCTACAA 
CAATTTTGCG ACATCAAGAA GGAGATATTT CAGATTAACT TGCAGATGTT GATGTCAGCC 
TCAAGCACAC CACCTCCGAA GCTTGAGCTA AGCGCAGCGA TGGACCGCCT AGCTATAAGC 
TCTGGCTCAC CCAGCTCGGA TCCATTTGAC TCTCTACGCA CGATAAACGC TATCGAAGAG 
GCAGAAAGGA TTAACAACAT ACTTGTTAAT GAAATGAAAA TTGATCACTA TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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IKKbeta cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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