Xbp1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Xbp1
Entrez Gene ID	44226
Full Name	X box binding protein-1
Synonyms	138/3,CG 9415,CG9415,DM18,Dmel\CG9415,Dxbp-1,XBP-1,XBP1,Xbp-1,XbpI,anon-EST:Liang-1.41,clone 1.41,dXbp-1,l(2)k13803,xbp-1,xbp1
General protein information	Preferred Names X box binding protein-1 Names CG9415 gene product from transcript CG9415-RE CG9415-PD CG9415-PE X box binding protein 1 X-box binding protein X-box-binding protein 1 Xbp1-PD Xbp1-PE
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 57C3-57C4

mRNA and Protein(s)

mRNA	Protein	Name
NM_166427.4	NP_726032.4	X box binding protein-1, isoform E
NM_079983.4	NP_524722.2	X box binding protein-1, isoform D

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Xbp1	NP_726032.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010623	XP_310116.4

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Its activation is neuroprotective and enhances Abeta42 clearance.
Title: Amyloid-?42 clearance and neuroprotection mediated by X-box binding protein 1 signaling decline with aging in the Drosophila brain.

Ire1-dependent splicing of Xbp1 mRNA is reduced.
Title: Ire1 mediated mRNA splicing in a C-terminus deletion mutant of Drosophila Xbp1.

role of Ire1 during photoreceptor differentiation is independent of Xbp1 function and demonstrate the physiological relevance of the RIDD mechanism in this specific paradigm.
Title: Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila.

In the larval brain, IRE1/XBP1 activity was detected exclusively in glia, although previous reports have largely focused on IRE1/XBP1 activity in neurons.
Title: A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila development.

The XBP1 promoter activity is enhanced in secretory tissues of Drosophila, and can be induced by excessive endoplasmic reticulum stress.
Title: Drosophila XBP1 expression reporter marks cells under endoplasmic reticulum stress and with high protein secretory load.

The following Xbp1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Xbp1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa11335	NM_079983.4 Latest version!	Drosophila melanogaster X box binding protein-1 (Xbp1), transcript variant D, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa11336	NM_166427.4 Latest version!	Drosophila melanogaster X box binding protein-1 (Xbp1), transcript variant E, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Xbp1 ( NM_079983.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_524722.2 Drosophila melanogaster X box binding protein-1 (Xbp1), transcript variant D, mRNA.

Price & Availability↑

CloneID	OFa11335
Clone ID Related Accession (Same CDS sequence)	NM_079983.4
Accession Version	NM_079983.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	X box binding protein-1, isoform D
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_079983.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCACCCA CAGCAAACAC AGTGCTAATT ACCGTGCCGC GGACAGCAAT CACATCGAAT 
AATCTGCCCA AATTGCGGCC CGCCCCCCTT ACGGCAGCTC TGCTGAAGGT GTCGGCCACG 
CCCTCCGCCT CGCCCACGCC CTCGAGTTCG GGATACGCAT CCTCGTCGAA CATGGATGAC 
GATAACATGG CTGCATCCCA GCCCAAGGCC AAGAAGCGTC GCCTGGACCA TCTAACCTGG 
GAGGAGAAAG TGCAAAGAAA GAAGCTAAAG AACCGTGTGG CCGCCCAGAC ATCGCGTGAC 
CGCAAGAAGG CACGCATGGA GGAGATGGAC TACGAGATCA AGGAGCTGAC AGACAGAACG 
GAAATACTAC AGAACAAGTG CGATAGCCTG CAGGCCATCA ACGAGTCACT GCTGGCCAAG 
AACCACAAGC TGGACTCGGA GCTGGAGCTG CTGCGCCAAG AACTCGCCGA ACTGAAGCAG 
CAACAGCAGC ACAACACCAG ATGCATCAGC CAATCCAACG CCAGCGCAGG CGCTGAGGGC 
TGTGCGTCCA CCAACCTTGG ATCTGCAGCA TCCAAAGCTG ACCCTCTGCC GCAGGGTATA 
CAACAGGTGG ACACACAGTC GTCAGCGCGT CTGCTGGCGG AGCAGCTGAA GAGCAGCAAG 
AGCCTGGCCT CACTCTGGAA AGTTGTGGCC CTCTGCCTAC TCTACAAGAC ATGCTTGGCG 
TCGACGAAGA GTTCGACGTC AAGCGCCTCG AAGAGCTGGC CGAAAGTCTG CTCGCAGATA 
TCACAGCAGA CCTGGAAACA GGCGCTGGAG CGAGCAGCCC AGCTGCTGCC CAAGATGCAG 
GCAACGCAGA GCGATTGCCT GGACCAATGG TGGGGCCCGC AGCAGAGCGC TTGGAATCCG 
ACGGGCATAG AGCTAATGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_524722.2
CDS	329..1252
Translation	MAPTANTVLITVPRTAITSNNLPKLRPAPLTAALLKVSATPSASPTPSSSGYASSSNMDDDNMAASQPKAKKRRLDHLTWEEKVQRKKLKNRVAAQTSRDRKKARMEEMDYEIKELTDRTEILQNKCDSLQAINESLLAKNHKLDSELELLRQELAELKQQQQHNTRCISQSNASAGAEGCASTNLGSAASKADPLPQGIQQVDTQSSARLLAEQLKSSKSLASLWKVVALCLLYKTCLASTKSSTSSASKSWPKVCSQISQQTWKQALERAAQLLPKMQATQSDCLDQWWGPQQSAWNPTGIELMA

Target ORF information:

RefSeq Version	NM_079983.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster X box binding protein-1 (Xbp1), transcript variant D, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_079983.4

ORF Insert Sequence:

ATGGCACCCA CAGCAAACAC AGTGCTAATT ACCGTGCCGC GGACAGCAAT CACATCGAAT 
AATCTGCCCA AATTGCGGCC CGCCCCCCTT ACGGCAGCTC TGCTGAAGGT GTCGGCCACG 
CCCTCCGCCT CGCCCACGCC CTCGAGTTCG GGATACGCAT CCTCGTCGAA CATGGATGAC 
GATAACATGG CTGCATCCCA GCCCAAGGCC AAGAAGCGTC GCCTGGACCA TCTAACCTGG 
GAGGAGAAAG TGCAAAGAAA GAAGCTAAAG AACCGTGTGG CCGCCCAGAC ATCGCGTGAC 
CGCAAGAAGG CACGCATGGA GGAGATGGAC TACGAGATCA AGGAGCTGAC AGACAGAACG 
GAAATACTAC AGAACAAGTG CGATAGCCTG CAGGCCATCA ACGAGTCACT GCTGGCCAAG 
AACCACAAGC TGGACTCGGA GCTGGAGCTG CTGCGCCAAG AACTCGCCGA ACTGAAGCAG 
CAACAGCAGC ACAACACCAG ATGCATCAGC CAATCCAACG CCAGCGCAGG CGCTGAGGGC 
TGTGCGTCCA CCAACCTTGG ATCTGCAGCA TCCAAAGCTG ACCCTCTGCC GCAGGGTATA 
CAACAGGTGG ACACACAGTC GTCAGCGCGT CTGCTGGCGG AGCAGCTGAA GAGCAGCAAG 
AGCCTGGCCT CACTCTGGAA AGTTGTGGCC CTCTGCCTAC TCTACAAGAC ATGCTTGGCG 
TCGACGAAGA GTTCGACGTC AAGCGCCTCG AAGAGCTGGC CGAAAGTCTG CTCGCAGATA 
TCACAGCAGA CCTGGAAACA GGCGCTGGAG CGAGCAGCCC AGCTGCTGCC CAAGATGCAG 
GCAACGCAGA GCGATTGCCT GGACCAATGG TGGGGCCCGC AGCAGAGCGC TTGGAATCCG 
ACGGGCATAG AGCTAATGGC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Xbp1 ( NM_166427.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_726032.4 Drosophila melanogaster X box binding protein-1 (Xbp1), transcript variant E, mRNA.

Price & Availability↑

CloneID	OFa11336
Clone ID Related Accession (Same CDS sequence)	NM_166427.4
Accession Version	NM_166427.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1497bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	X box binding protein-1, isoform E
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_166427.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGCACCCA CAGCAAACAC AGTGCTAATT ACCGTGCCGC GGACAGCAAT CACATCGAAT 
AATCTGCCCA AATTGCGGCC CGCCCCCCTT ACGGCAGCTC TGCTGAAGGT GTCGGCCACG 
CCCTCCGCCT CGCCCACGCC CTCGAGTTCG GGATACGCAT CCTCGTCGAA CATGGATGAC 
GATAACATGG CTGCATCCCA GCCCAAGGCC AAGAAGCGTC GCCTGGACCA TCTAACCTGG 
GAGGAGAAAG TGCAAAGAAA GAAGCTAAAG AACCGTGTGG CCGCCCAGAC ATCGCGTGAC 
CGCAAGAAGG CACGCATGGA GGAGATGGAC TACGAGATCA AGGAGCTGAC AGACAGAACG 
GAAATACTAC AGAACAAGTG CGATAGCCTG CAGGCCATCA ACGAGTCACT GCTGGCCAAG 
AACCACAAGC TGGACTCGGA GCTGGAGCTG CTGCGCCAAG AACTCGCCGA ACTGAAGCAG 
CAACAGCAGC ACAACACCAG ATGCATCAGC CAATCCAACG CCAGCGCAGG CGCTGAGGGC 
TGTGCGTCCA CCAACCTTGG ATCTGCCGCA GGGTATACAA CAGGTGGACA CACAGTCGTC 
AGCGCGTCTG CTGGCGGAGC AGCTGAAGAG CAGCAAGAGC CTGGCCTCAC TCTGGAAAGT 
TGTGGCCCTC TGCCTACTCT ACAAGACATG CTTGGCGTCG ACGAAGAGTT CGACGTCAAG 
CGCCTCGAAG AGCTGGCCGA AAGTCTGCTC GCAGATATCA CAGCAGACCT GGAAACAGGC 
GCTGGAGCGA GCAGCCCAGC TGCTGCCCAA GATGCAGGCA ACGCAGAGCG ATTGCCTGGA 
CCAATGGTGG GGCCCGCAGC AGAGCGCTTG GAATCCGACG GGCATAGAGC TAATGGCCTG 
AATGTTGAGC AGGAACAGGA AACCGAGCAC AAGGTCAGCC TAAATGTGCA GATGTTGAAG 
ATAAATGGAA ACCCACAGCA TACCACAGCA GCGCCAGCCT CGAGAACAGC CACAATCACA 
GCGACAGCGG CCGCCTCGCA ACTACAGGCC ACTCCGGACA CAGTGTACGG CACGTATGAT 
GCCAAGACGA ACTCGATCAC CATCGTGATG GACGGGGATG CGGTGCCGGT GAACGAGGCC 
GTCGAGGAGA TCTACTGTGA CGGCGTCAGC GCTGGCGACG ACTCAACGGA CGTGATCATG 
AAGTGTCCGC CGCCAGCGAC GTCTCCGTCA CAGGTCTATC TCAACGTGAT GAACGCCGTC 
GACAATTCGG ACGACGAGGA AAGCTTCGAT CCGATCGACC GATTCCTACG TCCGCGCGTT 
AAGGCGATCT CCCCGTTGGC CAAATCCCCC GCATTGTCTC TACACTCGGC CACCTCGGAC 
CATGGATACG AGTCCATACT GGGCTCTCCC ACATCCGTGG CTCTCACTCT GCCCGCAGAT 
GAGGACGATT TCCCCTGGGA GAGCAACTTT GACGAGCTGT TTCCCAGTTT GATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_726032.4
CDS	333..1829
Translation	MAPTANTVLITVPRTAITSNNLPKLRPAPLTAALLKVSATPSASPTPSSSGYASSSNMDDDNMAASQPKAKKRRLDHLTWEEKVQRKKLKNRVAAQTSRDRKKARMEEMDYEIKELTDRTEILQNKCDSLQAINESLLAKNHKLDSELELLRQELAELKQQQQHNTRCISQSNASAGAEGCASTNLGSAAGYTTGGHTVVSASAGGAAEEQQEPGLTLESCGPLPTLQDMLGVDEEFDVKRLEELAESLLADITADLETGAGASSPAAAQDAGNAERLPGPMVGPAAERLESDGHRANGLNVEQEQETEHKVSLNVQMLKINGNPQHTTAAPASRTATITATAAASQLQATPDTVYGTYDAKTNSITIVMDGDAVPVNEAVEEIYCDGVSAGDDSTDVIMKCPPPATSPSQVYLNVMNAVDNSDDEESFDPIDRFLRPRVKAISPLAKSPALSLHSATSDHGYESILGSPTSVALTLPADEDDFPWESNFDELFPSLI

Target ORF information:

RefSeq Version	NM_166427.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster X box binding protein-1 (Xbp1), transcript variant E, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_166427.4

ORF Insert Sequence:

ATGGCACCCA CAGCAAACAC AGTGCTAATT ACCGTGCCGC GGACAGCAAT CACATCGAAT 
AATCTGCCCA AATTGCGGCC CGCCCCCCTT ACGGCAGCTC TGCTGAAGGT GTCGGCCACG 
CCCTCCGCCT CGCCCACGCC CTCGAGTTCG GGATACGCAT CCTCGTCGAA CATGGATGAC 
GATAACATGG CTGCATCCCA GCCCAAGGCC AAGAAGCGTC GCCTGGACCA TCTAACCTGG 
GAGGAGAAAG TGCAAAGAAA GAAGCTAAAG AACCGTGTGG CCGCCCAGAC ATCGCGTGAC 
CGCAAGAAGG CACGCATGGA GGAGATGGAC TACGAGATCA AGGAGCTGAC AGACAGAACG 
GAAATACTAC AGAACAAGTG CGATAGCCTG CAGGCCATCA ACGAGTCACT GCTGGCCAAG 
AACCACAAGC TGGACTCGGA GCTGGAGCTG CTGCGCCAAG AACTCGCCGA ACTGAAGCAG 
CAACAGCAGC ACAACACCAG ATGCATCAGC CAATCCAACG CCAGCGCAGG CGCTGAGGGC 
TGTGCGTCCA CCAACCTTGG ATCTGCCGCA GGGTATACAA CAGGTGGACA CACAGTCGTC 
AGCGCGTCTG CTGGCGGAGC AGCTGAAGAG CAGCAAGAGC CTGGCCTCAC TCTGGAAAGT 
TGTGGCCCTC TGCCTACTCT ACAAGACATG CTTGGCGTCG ACGAAGAGTT CGACGTCAAG 
CGCCTCGAAG AGCTGGCCGA AAGTCTGCTC GCAGATATCA CAGCAGACCT GGAAACAGGC 
GCTGGAGCGA GCAGCCCAGC TGCTGCCCAA GATGCAGGCA ACGCAGAGCG ATTGCCTGGA 
CCAATGGTGG GGCCCGCAGC AGAGCGCTTG GAATCCGACG GGCATAGAGC TAATGGCCTG 
AATGTTGAGC AGGAACAGGA AACCGAGCAC AAGGTCAGCC TAAATGTGCA GATGTTGAAG 
ATAAATGGAA ACCCACAGCA TACCACAGCA GCGCCAGCCT CGAGAACAGC CACAATCACA 
GCGACAGCGG CCGCCTCGCA ACTACAGGCC ACTCCGGACA CAGTGTACGG CACGTATGAT 
GCCAAGACGA ACTCGATCAC CATCGTGATG GACGGGGATG CGGTGCCGGT GAACGAGGCC 
GTCGAGGAGA TCTACTGTGA CGGCGTCAGC GCTGGCGACG ACTCAACGGA CGTGATCATG 
AAGTGTCCGC CGCCAGCGAC GTCTCCGTCA CAGGTCTATC TCAACGTGAT GAACGCCGTC 
GACAATTCGG ACGACGAGGA AAGCTTCGAT CCGATCGACC GATTCCTACG TCCGCGCGTT 
AAGGCGATCT CCCCGTTGGC CAAATCCCCC GCATTGTCTC TACACTCGGC CACCTCGGAC 
CATGGATACG AGTCCATACT GGGCTCTCCC ACATCCGTGG CTCTCACTCT GCCCGCAGAT 
GAGGACGATT TCCCCTGGGA GAGCAACTTT GACGAGCTGT TTCCCAGTTT GATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Xbp1 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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