CG3301 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	CG3301
Entrez Gene ID	42528
Full Name	CG3301 gene product from transcript CG3301-RB
Synonyms	Dmel\CG3301,FOHSDR
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 3R Map Location: 93D2-93D2

mRNA and Protein(s)

mRNA	Protein	Name
NM_142707.3	NP_650964.1	uncharacterized protein, isoform A
NM_169954.2	NP_732612.1	uncharacterized protein, isoform B
NM_001300511.1	NP_001287440.1	uncharacterized protein, isoform C

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	CG3301	NP_650964.1
Drosophila melanogaster (fruit fly)	CG9360	NP_572746.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following CG3301 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CG3301 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OFa05591	NM_001300511.1 Latest version!	Drosophila melanogaster uncharacterized protein, transcript variant C (CG3301), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa05591	NM_142707.3 Latest version!	Drosophila melanogaster uncharacterized protein, transcript variant A (CG3301), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa05591	NM_169954.2 Latest version!	Drosophila melanogaster uncharacterized protein, transcript variant B (CG3301), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CG3301 ( NM_142707.3 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_650964.1 Drosophila melanogaster uncharacterized protein, transcript variant A (CG3301), mRNA.

Price & Availability↑

CloneID	OFa05591
Clone ID Related Accession (Same CDS sequence)	NM_142707.3 , NM_169954.2 , NM_001300511.1
Accession Version	NM_142707.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	uncharacterized protein, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_142707.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAACCGCT GGTTGAATCG CGTTGCCGTA GTCACTGGTG CCAGCGCCGG AATCGGAGCA 
GCCTGCTGCC GCGATCTGGT GGCCAAGGGA ATGGTAGTGG TGGGCCTGGC CAGGAGAGAG 
AAGGTCCTCC AGGACATCAA ATCCTCCCTG CCCGCCGATC AGGCTGCTCG CTTCCACACC 
CGCCCCTGTG ATGTCAGCAA TGAACAGCAG GTCATCGATA CCTTCGCCTG GATCGATCGC 
ACCCTGGGTG GTGCCGACGT GCTTGTCAAT AACGCCGGGA TCATACGTCA AATGAACATC 
ACGGACCCGG AAAATTCCGC TGATGTGCGT GCCATTCTGG ACGTGAATGT GTTGGGAGTG 
ACCTGGTGCA CCCGCCAGTG GTTCCTATCG CTGCAGCGCC GCAAGGTAAA CGACGGTCAT 
GTGGTAGTCA TCAATAGTGT GGTAGGCCAC TCCGTTCCGG CCGTGGAGGG CTTCAGCCTG 
AACATGTACG CGCCCTCCAA ACACGCGATC ACCGCCTTGA CCGAAATCCT GCGTCAGGAG 
TTCATCAAGA AGGGCACTCA AACAAAGATC ACGAGCATCA GTCCTGGTGT AGTGGCCACT 
GAAATTTTCG AAGCCGGATC CTGGGAGCAA CCCACAGGCA TGCCCATGCT GCGATCGGAG 
GATATAGCCG ATGCGGTGAC CTACTGCATC CAGACGCCCC CAACTGTCCA GATAAAGGAG 
CTCATAATCA AGCCGGTTGG TGAGGGCTTT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_650964.1
CDS	39..791
Translation	MNRWLNRVAVVTGASAGIGAACCRDLVAKGMVVVGLARREKVLQDIKSSLPADQAARFHTRPCDVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADVRAILDVNVLGVTWCTRQWFLSLQRRKVNDGHVVVINSVVGHSVPAVEGFSLNMYAPSKHAITALTEILRQEFIKKGTQTKITSISPGVVATEIFEAGSWEQPTGMPMLRSEDIADAVTYCIQTPPTVQIKELIIKPVGEGF

Target ORF information:

RefSeq Version	NM_142707.3
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster uncharacterized protein, transcript variant A (CG3301), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_142707.3

ORF Insert Sequence:

ATGAACCGCT GGTTGAATCG CGTTGCCGTA GTCACTGGTG CCAGCGCCGG AATCGGAGCA 
GCCTGCTGCC GCGATCTGGT GGCCAAGGGA ATGGTAGTGG TGGGCCTGGC CAGGAGAGAG 
AAGGTCCTCC AGGACATCAA ATCCTCCCTG CCCGCCGATC AGGCTGCTCG CTTCCACACC 
CGCCCCTGTG ATGTCAGCAA TGAACAGCAG GTCATCGATA CCTTCGCCTG GATCGATCGC 
ACCCTGGGTG GTGCCGACGT GCTTGTCAAT AACGCCGGGA TCATACGTCA AATGAACATC 
ACGGACCCGG AAAATTCCGC TGATGTGCGT GCCATTCTGG ACGTGAATGT GTTGGGAGTG 
ACCTGGTGCA CCCGCCAGTG GTTCCTATCG CTGCAGCGCC GCAAGGTAAA CGACGGTCAT 
GTGGTAGTCA TCAATAGTGT GGTAGGCCAC TCCGTTCCGG CCGTGGAGGG CTTCAGCCTG 
AACATGTACG CGCCCTCCAA ACACGCGATC ACCGCCTTGA CCGAAATCCT GCGTCAGGAG 
TTCATCAAGA AGGGCACTCA AACAAAGATC ACGAGCATCA GTCCTGGTGT AGTGGCCACT 
GAAATTTTCG AAGCCGGATC CTGGGAGCAA CCCACAGGCA TGCCCATGCT GCGATCGGAG 
GATATAGCCG ATGCGGTGAC CTACTGCATC CAGACGCCCC CAACTGTCCA GATAAAGGAG 
CTCATAATCA AGCCGGTTGG TGAGGGCTTT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CG3301 ( NM_169954.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_732612.1 Drosophila melanogaster uncharacterized protein, transcript variant B (CG3301), mRNA.

Price & Availability↑

CloneID	OFa05591
Clone ID Related Accession (Same CDS sequence)	NM_142707.3 , NM_169954.2 , NM_001300511.1
Accession Version	NM_169954.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	uncharacterized protein, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). On Jul 15, 2014 this sequence version replaced NM_169954.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAACCGCT GGTTGAATCG CGTTGCCGTA GTCACTGGTG CCAGCGCCGG AATCGGAGCA 
GCCTGCTGCC GCGATCTGGT GGCCAAGGGA ATGGTAGTGG TGGGCCTGGC CAGGAGAGAG 
AAGGTCCTCC AGGACATCAA ATCCTCCCTG CCCGCCGATC AGGCTGCTCG CTTCCACACC 
CGCCCCTGTG ATGTCAGCAA TGAACAGCAG GTCATCGATA CCTTCGCCTG GATCGATCGC 
ACCCTGGGTG GTGCCGACGT GCTTGTCAAT AACGCCGGGA TCATACGTCA AATGAACATC 
ACGGACCCGG AAAATTCCGC TGATGTGCGT GCCATTCTGG ACGTGAATGT GTTGGGAGTG 
ACCTGGTGCA CCCGCCAGTG GTTCCTATCG CTGCAGCGCC GCAAGGTAAA CGACGGTCAT 
GTGGTAGTCA TCAATAGTGT GGTAGGCCAC TCCGTTCCGG CCGTGGAGGG CTTCAGCCTG 
AACATGTACG CGCCCTCCAA ACACGCGATC ACCGCCTTGA CCGAAATCCT GCGTCAGGAG 
TTCATCAAGA AGGGCACTCA AACAAAGATC ACGAGCATCA GTCCTGGTGT AGTGGCCACT 
GAAATTTTCG AAGCCGGATC CTGGGAGCAA CCCACAGGCA TGCCCATGCT GCGATCGGAG 
GATATAGCCG ATGCGGTGAC CTACTGCATC CAGACGCCCC CAACTGTCCA GATAAAGGAG 
CTCATAATCA AGCCGGTTGG TGAGGGCTTT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_732612.1
CDS	39..791
Translation	MNRWLNRVAVVTGASAGIGAACCRDLVAKGMVVVGLARREKVLQDIKSSLPADQAARFHTRPCDVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADVRAILDVNVLGVTWCTRQWFLSLQRRKVNDGHVVVINSVVGHSVPAVEGFSLNMYAPSKHAITALTEILRQEFIKKGTQTKITSISPGVVATEIFEAGSWEQPTGMPMLRSEDIADAVTYCIQTPPTVQIKELIIKPVGEGF

Target ORF information:

RefSeq Version	NM_169954.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster uncharacterized protein, transcript variant B (CG3301), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_169954.2

ORF Insert Sequence:

ATGAACCGCT GGTTGAATCG CGTTGCCGTA GTCACTGGTG CCAGCGCCGG AATCGGAGCA 
GCCTGCTGCC GCGATCTGGT GGCCAAGGGA ATGGTAGTGG TGGGCCTGGC CAGGAGAGAG 
AAGGTCCTCC AGGACATCAA ATCCTCCCTG CCCGCCGATC AGGCTGCTCG CTTCCACACC 
CGCCCCTGTG ATGTCAGCAA TGAACAGCAG GTCATCGATA CCTTCGCCTG GATCGATCGC 
ACCCTGGGTG GTGCCGACGT GCTTGTCAAT AACGCCGGGA TCATACGTCA AATGAACATC 
ACGGACCCGG AAAATTCCGC TGATGTGCGT GCCATTCTGG ACGTGAATGT GTTGGGAGTG 
ACCTGGTGCA CCCGCCAGTG GTTCCTATCG CTGCAGCGCC GCAAGGTAAA CGACGGTCAT 
GTGGTAGTCA TCAATAGTGT GGTAGGCCAC TCCGTTCCGG CCGTGGAGGG CTTCAGCCTG 
AACATGTACG CGCCCTCCAA ACACGCGATC ACCGCCTTGA CCGAAATCCT GCGTCAGGAG 
TTCATCAAGA AGGGCACTCA AACAAAGATC ACGAGCATCA GTCCTGGTGT AGTGGCCACT 
GAAATTTTCG AAGCCGGATC CTGGGAGCAA CCCACAGGCA TGCCCATGCT GCGATCGGAG 
GATATAGCCG ATGCGGTGAC CTACTGCATC CAGACGCCCC CAACTGTCCA GATAAAGGAG 
CTCATAATCA AGCCGGTTGG TGAGGGCTTT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CG3301 ( NM_001300511.1 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_001287440.1 Drosophila melanogaster uncharacterized protein, transcript variant C (CG3301), mRNA.

Price & Availability↑

CloneID	OFa05591
Clone ID Related Accession (Same CDS sequence)	NM_142707.3 , NM_169954.2 , NM_001300511.1
Accession Version	NM_001300511.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	uncharacterized protein, isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033777). ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGAACCGCT GGTTGAATCG CGTTGCCGTA GTCACTGGTG CCAGCGCCGG AATCGGAGCA 
GCCTGCTGCC GCGATCTGGT GGCCAAGGGA ATGGTAGTGG TGGGCCTGGC CAGGAGAGAG 
AAGGTCCTCC AGGACATCAA ATCCTCCCTG CCCGCCGATC AGGCTGCTCG CTTCCACACC 
CGCCCCTGTG ATGTCAGCAA TGAACAGCAG GTCATCGATA CCTTCGCCTG GATCGATCGC 
ACCCTGGGTG GTGCCGACGT GCTTGTCAAT AACGCCGGGA TCATACGTCA AATGAACATC 
ACGGACCCGG AAAATTCCGC TGATGTGCGT GCCATTCTGG ACGTGAATGT GTTGGGAGTG 
ACCTGGTGCA CCCGCCAGTG GTTCCTATCG CTGCAGCGCC GCAAGGTAAA CGACGGTCAT 
GTGGTAGTCA TCAATAGTGT GGTAGGCCAC TCCGTTCCGG CCGTGGAGGG CTTCAGCCTG 
AACATGTACG CGCCCTCCAA ACACGCGATC ACCGCCTTGA CCGAAATCCT GCGTCAGGAG 
TTCATCAAGA AGGGCACTCA AACAAAGATC ACGAGCATCA GTCCTGGTGT AGTGGCCACT 
GAAATTTTCG AAGCCGGATC CTGGGAGCAA CCCACAGGCA TGCCCATGCT GCGATCGGAG 
GATATAGCCG ATGCGGTGAC CTACTGCATC CAGACGCCCC CAACTGTCCA GATAAAGGAG 
CTCATAATCA AGCCGGTTGG TGAGGGCTTT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001287440.1
CDS	39..791
Translation	MNRWLNRVAVVTGASAGIGAACCRDLVAKGMVVVGLARREKVLQDIKSSLPADQAARFHTRPCDVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADVRAILDVNVLGVTWCTRQWFLSLQRRKVNDGHVVVINSVVGHSVPAVEGFSLNMYAPSKHAITALTEILRQEFIKKGTQTKITSISPGVVATEIFEAGSWEQPTGMPMLRSEDIADAVTYCIQTPPTVQIKELIIKPVGEGF

Target ORF information:

RefSeq Version	NM_001300511.1
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster uncharacterized protein, transcript variant C (CG3301), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001300511.1

ORF Insert Sequence:

ATGAACCGCT GGTTGAATCG CGTTGCCGTA GTCACTGGTG CCAGCGCCGG AATCGGAGCA 
GCCTGCTGCC GCGATCTGGT GGCCAAGGGA ATGGTAGTGG TGGGCCTGGC CAGGAGAGAG 
AAGGTCCTCC AGGACATCAA ATCCTCCCTG CCCGCCGATC AGGCTGCTCG CTTCCACACC 
CGCCCCTGTG ATGTCAGCAA TGAACAGCAG GTCATCGATA CCTTCGCCTG GATCGATCGC 
ACCCTGGGTG GTGCCGACGT GCTTGTCAAT AACGCCGGGA TCATACGTCA AATGAACATC 
ACGGACCCGG AAAATTCCGC TGATGTGCGT GCCATTCTGG ACGTGAATGT GTTGGGAGTG 
ACCTGGTGCA CCCGCCAGTG GTTCCTATCG CTGCAGCGCC GCAAGGTAAA CGACGGTCAT 
GTGGTAGTCA TCAATAGTGT GGTAGGCCAC TCCGTTCCGG CCGTGGAGGG CTTCAGCCTG 
AACATGTACG CGCCCTCCAA ACACGCGATC ACCGCCTTGA CCGAAATCCT GCGTCAGGAG 
TTCATCAAGA AGGGCACTCA AACAAAGATC ACGAGCATCA GTCCTGGTGT AGTGGCCACT 
GAAATTTTCG AAGCCGGATC CTGGGAGCAA CCCACAGGCA TGCCCATGCT GCGATCGGAG 
GATATAGCCG ATGCGGTGAC CTACTGCATC CAGACGCCCC CAACTGTCCA GATAAAGGAG 
CTCATAATCA AGCCGGTTGG TGAGGGCTTT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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CG3301 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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