Gene Symbol | mad2 |
Entrez Gene ID | 38656 |
Full Name | CG17498 gene product from transcript CG17498-RA |
Synonyms | CG17498,Dmel\CG17498,MAD2,Mad2 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » mad2 cDNA ORF clone
Gene Symbol | mad2 |
Entrez Gene ID | 38656 |
Full Name | CG17498 gene product from transcript CG17498-RA |
Synonyms | CG17498,Dmel\CG17498,MAD2,Mad2 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_139734.3 | NP_647991.1 | mad2 |
Danio rerio (zebrafish) | mad2l1 | NP_001017739.1 |
Kluyveromyces lactis | KLLA0D09438g | XP_453482.1 |
Pan troglodytes (chimpanzee) | MAD2L1 | XP_003310508.1 |
MAD2L1 | XP_001097054.2 | |
Saccharomyces cerevisiae (baker's yeast) | MAD2 | NP_012504.3 |
Eremothecium gossypii | AGOS_ACR043W | NP_983446.1 |
Gallus gallus (chicken) | MAD2L1 | NP_001264678.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08269 | XP_003715816.1 |
Arabidopsis thaliana (thale cress) | MAD2 | NP_189227.1 |
Homo sapiens (human) | MAD2L1 | NP_002349.1 |
Bos taurus (cattle) | MAD2L1 | NP_001178442.1 |
Mus musculus (house mouse) | Mad2l1 | NP_062372.2 |
Drosophila melanogaster (fruit fly) | mad2 | NP_647991.1 |
Schizosaccharomyces pombe (fission yeast) | mad2 | NP_596370.1 |
Oryza sativa (rice) | Os04g0486500 | NP_001053138.1 |
Canis lupus familiaris (dog) | LOC476070 | XP_533278.2 |
Rattus norvegicus (Norway rat) | Mad2l1 | NP_001100064.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000751 | XP_311286.5 |
Caenorhabditis elegans (roundworm) | mdf-2 | NP_001023563.1 |
Neurospora crassa | NCU05781 | XP_960041.2 |
Xenopus tropicalis (tropical clawed frog) | mad2l1 | NP_001096528.1 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Kinetochore localized Mad2 and Cdc20 is itself insufficient for triggering the mitotic checkpoint when Mps1 is low in Drosophila melanogaster neuroblasts.
Title: Kinetochore localized Mad2 and Cdc20 is itself insufficient for triggering the mitotic checkpoint when Mps1 is low in Drosophila melanogaster neuroblasts.
Data show that the Mad2 kinetochore dimerization recruitment mechanism is conserved and that the recruitment of Cdc20 to kinetochores in Drosophila requires BubR1 but not Mad2.
Title: Recruitment of Cdc20 to the kinetochore requires BubR1 but not Mad2 in Drosophila melanogaster.
These results strongly suggest that Mad2 is exclusively required to delay progression through early stages of prometaphase so that cells have time to fully engage the spindle assembly checkpoint.
Title: Mad2-independent spindle assembly checkpoint activation and controlled metaphase-anaphase transition in Drosophila S2 cells.
The following mad2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mad2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa17633 | |
Clone ID Related Accession (Same CDS sequence) | NM_139734.3 | |
Accession Version | NM_139734.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 624bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | mad2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_037436). On Jan 16, 2013 this sequence version replaced NM_139734.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTCAACTG CCCAGGCGAC CAAAAACTGC ATCACACTCA AGGGCTCCGC TCAGATTATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_647991.1 |
CDS | 80..703 |
Translation |
Target ORF information:
Target ORF information:
|
NM_139734.3 |
1 | ATGTCAACTG CCCAGGCGAC CAAAAACTGC ATCACACTCA AGGGCTCCGC TCAGATTATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |