Gene Symbol | Rae1 |
Entrez Gene ID | 37467 |
Full Name | CG9862 gene product from transcript CG9862-RA |
Synonyms | CG9862,Dmel\CG9862,dmrae1,rae1 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
ORF » Species Summary » Drosophila melanogaster » Rae1 cDNA ORF clone
Gene Symbol | Rae1 |
Entrez Gene ID | 37467 |
Full Name | CG9862 gene product from transcript CG9862-RA |
Synonyms | CG9862,Dmel\CG9862,dmrae1,rae1 |
Gene Type | protein-coding |
Organism | Drosophila melanogaster(fruit fly) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_137753.3 | NP_611597.1 | Rae1 |
Gallus gallus (chicken) | RAE1 | NP_001026039.2 |
Danio rerio (zebrafish) | rae1 | NP_957292.1 |
Drosophila melanogaster (fruit fly) | Rae1 | NP_611597.1 |
Neurospora crassa | NCU04288 | XP_961078.1 |
Pan troglodytes (chimpanzee) | RAE1 | XP_003953827.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012373 | XP_320184.3 |
Eremothecium gossypii | AGOS_AGL301C | NP_986366.1 |
Schizosaccharomyces pombe (fission yeast) | rae1 | NP_596784.1 |
RAE1 | XP_001088020.2 | |
Mus musculus (house mouse) | Rae1 | NP_780321.1 |
Rattus norvegicus (Norway rat) | Rae1 | NP_001028880.1 |
Caenorhabditis elegans (roundworm) | rae-1 | NP_492650.1 |
Kluyveromyces lactis | KLLA0E20703g | XP_454886.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00946 | XP_003718005.1 |
Bos taurus (cattle) | RAE1 | NP_001015585.1 |
Saccharomyces cerevisiae (baker's yeast) | GLE2 | NP_011033.3 |
Arabidopsis thaliana (thale cress) | AT1G80670 | NP_178182.1 |
Xenopus tropicalis (tropical clawed frog) | rae1 | NP_001017142.1 |
Homo sapiens (human) | RAE1 | NP_001015885.1 |
Canis lupus familiaris (dog) | RAE1 | XP_005635265.1 |
Oryza sativa (rice) | Os08g0176800 | NP_001061119.1 |
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The distribution of Moesin in the nucleus suggests a function in transcription and the depletion of mRNA export factors Nup98 or its interacting partner, Rae1, leads to the nuclear accumulation of Moesin, suggesting that the nuclear function of the protein is linked to mRNA export
Title: The actin binding cytoskeletal protein Moesin is involved in nuclear mRNA export.
Rae1 increases activation of the core kinases Hippo and Warts and plays a post-transcriptional role to increase the protein levels of the Merlin, Hippo, and Warts components of the pathway; therefore, in addition to Rae1 coordinating organ size regulation with proliferative control, we propose that Rae1 also acts in a feedback circuit to regulate pathway homeostas
Title: The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts.
This study demonistrated taht Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.
Title: Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.
mainly localises to the nuclear membrane; the presence of dmRae1 is important for normal proliferation and, more importantly, for the progression through the G1 phase of the cell cycle
Title: Characterization of the Drosophila Rae1 protein as a G1 phase regulator of the cell cycle.
The following Rae1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rae1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OFa10833 | |
Clone ID Related Accession (Same CDS sequence) | NM_137753.3 | |
Accession Version | NM_137753.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-24 | |
Organism | Drosophila melanogaster(fruit fly) | |
Product | Rae1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jul 15, 2014 this sequence version replaced NM_137753.2. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END## |
1 | ATGTTTGGCG CCACACAATC GACGAACCGA ATGAACGACT TCGAGGTCGC CTCGCCGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_611597.1 |
CDS | 76..1116 |
Translation |
Target ORF information:
Target ORF information:
|
NM_137753.3 |
1 | ATGTTTGGCG CCACACAATC GACGAACCGA ATGAACGACT TCGAGGTCGC CTCGCCGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. |
Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. |
Sequence finishing and mapping of Drosophila melanogaster heterochromatin. |
The Release 5.1 annotation of Drosophila melanogaster heterochromatin. |
Combined evidence annotation of transposable elements in genome sequences. |