Lapsyn cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lapsyn
Entrez Gene ID	37418
Full Name	Leucine-rich repeat activity-regulated protein at synapses
Synonyms	CG15658,CT35842,Dmel\CG15658
General protein information	Preferred Names Leucine-rich repeat activity-regulated protein at synapses Names CG15658 gene product from transcript CG15658-RA CG15658-PA Lapsyn-PA
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2R Map Location: 57C9-57D1

mRNA and Protein(s)

mRNA	Protein	Name
NM_137717.4	NP_611561.1	Leucine-rich repeat activity-regulated protein at synapses

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006647	XP_001688943.1
Drosophila melanogaster (fruit fly)	Lapsyn	NP_611561.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate the role for the transmembrane leucine-rich repeat protein Lapsyn in regulating astrocyte-like medulla neuropil glia (mng) development.
Title: Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe.

The following Lapsyn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lapsyn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa10771	NM_137717.4 Latest version!	Drosophila melanogaster Leucine-rich repeat activity-regulated protein at synapses (Lapsyn), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lapsyn ( NM_137717.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_611561.1 Drosophila melanogaster Leucine-rich repeat activity-regulated protein at synapses (Lapsyn), mRNA.

Price & Availability↑

CloneID	OFa10771
Clone ID Related Accession (Same CDS sequence)	NM_137717.4
Accession Version	NM_137717.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1032bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	Leucine-rich repeat activity-regulated protein at synapses
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033778). On Jan 16, 2013 this sequence version replaced NM_137717.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGAACTGC ATTGGCAGCT GCTGACGTTC ATCGTGTGCC TCCAGTTGTT GCATTCCGCC 
GGATTCATCA TTCAGTCGGA AGTGCGCAAG TGCACGTACG GCCATATCGA TAAGCTGCTC 
CGGATTCGTT GCTACGACTT GGACCTCAAG GAGGTGCCAC AGAACCTCAA GAGTTCGGTG 
GAGGTTCTGG ATCTATCGCA CAATCGCATC AGGAAGCTGA AAACTAGCTC GTTTCAGCGA 
TACACGGACA TTAAGTTTCT GATGCTCTAT GATAACATGA TCTTATCGGT GGAGGTGGGA 
ACCTTCGAGC CACTCACCTC GCTCCAGGAA ATTGATCTTT CGAATAATGG ACTGACAACG 
ATACCGCTGG AGTTGTTCCA GCTGCCGCGA CTGAGAAACC TATACATCGA TAGCAATGAG 
CTAACATCCC TCAATCTTCA GGCACTGGAG AAGCCCATTC GTGCTCCACT GGAGTACCTG 
AACGTGGCAG GTTGCGAGCT ACAGGAGTTA CCCGATCTGG GCATACTTCC AAAACTCTGG 
CAACTGAATG CCTCGATGAA TCCGCTGCAG AACTTCAGGA TCGACAGCCT GGCGAATATG 
TGCCACCTGC AGGTCATCGA TCTGACCAAG TCGCAGTTGA GCCAGTGTGG CTGCCAGCAG 
GTCACCAACC ATCTTATGAT GCTCGGCGCC AGTCCGAAGT TCGTGCCAGT TTGCTTGGAG 
GCGCTCGACA TCCGCGAGTG TCCACTGCCC TACAATCGAA CGATCCATTC GCCAACATTC 
GCCAGTTGCC AGACGACACT GCAGTTTGCC GAAACGCGCA GCTTCTGGCT CTTTGGAGCT 
GGCTGCTTTG GCGGAGTTTG TTTTGTGCTT TTAATTGTCA TCTTCTGCGT GATACACTGT 
AGGAGAAAAC GAGCCCAGCG ACGAAAGAGG AATGCCCAGA AGCGAAAGCC GTTTGTGATC 
TCGCCCAGAA ACGCCATCAA CAACCGTCAG CCGGAGGACG AGCCTCTGCA CTGTGATATT 
GCCCGAAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_611561.1
CDS	300..1331
Translation	MELHWQLLTFIVCLQLLHSAGFIIQSEVRKCTYGHIDKLLRIRCYDLDLKEVPQNLKSSVEVLDLSHNRIRKLKTSSFQRYTDIKFLMLYDNMILSVEVGTFEPLTSLQEIDLSNNGLTTIPLELFQLPRLRNLYIDSNELTSLNLQALEKPIRAPLEYLNVAGCELQELPDLGILPKLWQLNASMNPLQNFRIDSLANMCHLQVIDLTKSQLSQCGCQQVTNHLMMLGASPKFVPVCLEALDIRECPLPYNRTIHSPTFASCQTTLQFAETRSFWLFGAGCFGGVCFVLLIVIFCVIHCRRKRAQRRKRNAQKRKPFVISPRNAINNRQPEDEPLHCDIARK

Target ORF information:

RefSeq Version	NM_137717.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster Leucine-rich repeat activity-regulated protein at synapses (Lapsyn), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_137717.4

ORF Insert Sequence:

ATGGAACTGC ATTGGCAGCT GCTGACGTTC ATCGTGTGCC TCCAGTTGTT GCATTCCGCC 
GGATTCATCA TTCAGTCGGA AGTGCGCAAG TGCACGTACG GCCATATCGA TAAGCTGCTC 
CGGATTCGTT GCTACGACTT GGACCTCAAG GAGGTGCCAC AGAACCTCAA GAGTTCGGTG 
GAGGTTCTGG ATCTATCGCA CAATCGCATC AGGAAGCTGA AAACTAGCTC GTTTCAGCGA 
TACACGGACA TTAAGTTTCT GATGCTCTAT GATAACATGA TCTTATCGGT GGAGGTGGGA 
ACCTTCGAGC CACTCACCTC GCTCCAGGAA ATTGATCTTT CGAATAATGG ACTGACAACG 
ATACCGCTGG AGTTGTTCCA GCTGCCGCGA CTGAGAAACC TATACATCGA TAGCAATGAG 
CTAACATCCC TCAATCTTCA GGCACTGGAG AAGCCCATTC GTGCTCCACT GGAGTACCTG 
AACGTGGCAG GTTGCGAGCT ACAGGAGTTA CCCGATCTGG GCATACTTCC AAAACTCTGG 
CAACTGAATG CCTCGATGAA TCCGCTGCAG AACTTCAGGA TCGACAGCCT GGCGAATATG 
TGCCACCTGC AGGTCATCGA TCTGACCAAG TCGCAGTTGA GCCAGTGTGG CTGCCAGCAG 
GTCACCAACC ATCTTATGAT GCTCGGCGCC AGTCCGAAGT TCGTGCCAGT TTGCTTGGAG 
GCGCTCGACA TCCGCGAGTG TCCACTGCCC TACAATCGAA CGATCCATTC GCCAACATTC 
GCCAGTTGCC AGACGACACT GCAGTTTGCC GAAACGCGCA GCTTCTGGCT CTTTGGAGCT 
GGCTGCTTTG GCGGAGTTTG TTTTGTGCTT TTAATTGTCA TCTTCTGCGT GATACACTGT 
AGGAGAAAAC GAGCCCAGCG ACGAAAGAGG AATGCCCAGA AGCGAAAGCC GTTTGTGATC 
TCGCCCAGAA ACGCCATCAA CAACCGTCAG CCGGAGGACG AGCCTCTGCA CTGTGATATT 
GCCCGAAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

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Lapsyn cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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