Su(var)205 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene
Clones
gRNAs

Summary

Gene Symbol	Su(var)205
Entrez Gene ID	34119
Full Name	Suppressor of variegation 205
Synonyms	CBX5,CG8409,DmHP-1,DmHP1,Dmel\CG8409,E(var)29,E(var)29A,FBgn0003607,HP-1,HP1,HP1-VS,HP1A,HP1a,HP1alpha,Hp1,Hp1a,SU(VAR)205,Su(Var)2-5,Su(Var)205,Su(var),Su(var)2-05,Su(var)2-5,Su(var)2-501,Su(var)29A,Su(var)[205],Su-var(2)5,Su[Var]205,Su[var]205,Suvar(2)5,Suvar2-5,dHP-1a,dHP1,hp1,hp1a,su(var)205
General protein information	Preferred Names Suppressor of variegation 205 Names CG8409 gene product from transcript CG8409-RA C1A9-nuclear-antigen CG8409-PA CG8409-PB Su(var)2-5 Su(var)205-PA Su(var)205-PB heterochromatic protein heterochromatic protein 1 heterochromatic protein 1a heterochromatin factor 1 heterochromatin protein 1 heterochromatin protein 1A heterochromatin protein-1 heterochromatin-binding protein heterochromatin-protein-1 histone protein 1 suppressor of variegated 205 suppressor of variegation 205
Gene Type	protein-coding
Organism	Drosophila melanogaster(fruit fly)
Genome	Chromosome: 2L Map Location: 28F2-28F3\|2-31.1 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_164799.2	NP_723361.1	suppressor of variegation 205, isoform B
NM_057407.4	NP_476755.1	suppressor of variegation 205, isoform A

Pathways from BioSystems

Homologies

Drosophila melanogaster (fruit fly)	Su(var)205	NP_723361.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009444	XP_307857.3

Gene Ontology
Bibliography

Related articles in PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Strelets V, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM,
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Hoskins RA, Carlson JW, Kennedy C, Acevedo D, Evans-Holm M, Frise E, Wan KH, Park S, Mendez-Lago M, Rossi F, Villasante A, Dimitri P, Karpen GH, Celniker SE
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Smith CD, Shu S, Mungall CJ, Karpen GH
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)

Combined evidence annotation of transposable elements in genome sequences.
Quesneville H, Bergman CM, Andrieu O, Autard D, Nouaud D, Ashburner M, Anxolabehere D
PLoS computational biology1(2)166-75(2005 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Knockdown of both HP1a and Mcm10 genes inhibited the progression of S phase in eye imaginal discs. Proximity Ligation Assay (PLA) demonstrated that HP1a is in close proximity to DNA replication proteins including Mcm10, RFC140 and DNA polymerase epsilon 255 kDa subunit in S-phase.
Title: Novel roles of HP1a and Mcm10 in DNA replication, genome maintenance and photoreceptor cell differentiation.

we show that Heterochromatin Protein 1a is required for the production of piRNAs coming from telomeric transposable elements. Furthermore, as in adult ovaries, incomplete, bimodal, and stochastic repression resembling variegation can occur at all developmental stages
Title: From Embryo to Adult: piRNA-Mediated Silencing throughout Germline Development in

Recruitment of either HP1GAL4DBD or SUURGAL4DBD resulted in delayed completion of replication
Title: Tethering of SUUR and HP1 proteins results in delayed replication of euchromatic regions in Drosophila melanogaster polytene chromosomes.

found that HP1a selectively associated with a broad set of RNAs transcribed from repetitive regions
Title: Heterochromatin-associated interactions of Drosophila HP1a with dADD1, HIPP1, and repetitive RNAs.

Results show that HP1 interacts with Med26.
Title: The metazoan-specific mediator subunit 26 (Med26) is essential for viability and is found at both active genes and pericentric heterochromatin in Drosophila melanogaster.

The following Su(var)205 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Su(var)205 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OFa14099	NM_057407.4 Latest version!	Drosophila melanogaster suppressor of variegation 205, transcript variant A (Su(var)205), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
OFa14099	NM_164799.2 Latest version!	Drosophila melanogaster suppressor of variegation 205, transcript variant B (Su(var)205), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Su(var)205 ( NM_164799.2 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_723361.1 Drosophila melanogaster suppressor of variegation 205, transcript variant B (Su(var)205), mRNA.

Price & Availability↑

CloneID	OFa14099
Clone ID Related Accession (Same CDS sequence)	NM_164799.2 , NM_057407.4
Accession Version	NM_164799.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	suppressor of variegation 205, isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_164799.1. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGGCAAGA AAATCGACAA CCCTGAGAGC TCGGCAAAGG TTTCCGATGC CGAAGAGGAG 
GAGGAGGAGT ACGCCGTGGA AAAGATCATC GACAGGCGGG TGCGCAAGGG AAAGGTGGAG 
TACTATCTGA AATGGAAGGG CTATCCCGAA ACTGAGAACA CGTGGGAGCC GGAGAACAAT 
CTCGACTGCC AGGATCTTAT CCAGCAGTAC GAGGCGAGCC GCAAGGATGA GGAGAAGTCA 
GCCGCCTCCA AGAAGGATCG ACCCAGCAGC AGCGCCAAGG CCAAGGAAAC TCAAGGACGC 
GCCAGCAGTT CGACGTCCAC AGCAAGCAAG CGAAAGTCCG AAGAACCAAC AGCGCCCTCT 
GGCAATAAAT CAAAACGTAC CACAGATGCG GAGCAGGACA CCATTCCCGT TTCAGGATCT 
ACCGGATTCG ATCGCGGCCT GGAGGCCGAA AAGATCTTGG GTGCCTCCGA CAATAATGGC 
CGCCTGACAT TCCTCATTCA GTTCAAAGGC GTGGACCAAG CAGAAATGGT GCCCTCCTCA 
GTGGCCAATG AAAAAATCCC ACGAATGGTA ATCCACTTCT ACGAAGAGCG CCTATCCTGG 
TACTCTGATA ATGAAGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_723361.1
CDS	280..900
Translation	MGKKIDNPESSAKVSDAEEEEEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKSAASKKDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAEQDTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEMVPSSVANEKIPRMVIHFYEERLSWYSDNED

Target ORF information:

RefSeq Version	NM_164799.2
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster suppressor of variegation 205, transcript variant B (Su(var)205), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_164799.2

ORF Insert Sequence:

ATGGGCAAGA AAATCGACAA CCCTGAGAGC TCGGCAAAGG TTTCCGATGC CGAAGAGGAG 
GAGGAGGAGT ACGCCGTGGA AAAGATCATC GACAGGCGGG TGCGCAAGGG AAAGGTGGAG 
TACTATCTGA AATGGAAGGG CTATCCCGAA ACTGAGAACA CGTGGGAGCC GGAGAACAAT 
CTCGACTGCC AGGATCTTAT CCAGCAGTAC GAGGCGAGCC GCAAGGATGA GGAGAAGTCA 
GCCGCCTCCA AGAAGGATCG ACCCAGCAGC AGCGCCAAGG CCAAGGAAAC TCAAGGACGC 
GCCAGCAGTT CGACGTCCAC AGCAAGCAAG CGAAAGTCCG AAGAACCAAC AGCGCCCTCT 
GGCAATAAAT CAAAACGTAC CACAGATGCG GAGCAGGACA CCATTCCCGT TTCAGGATCT 
ACCGGATTCG ATCGCGGCCT GGAGGCCGAA AAGATCTTGG GTGCCTCCGA CAATAATGGC 
CGCCTGACAT TCCTCATTCA GTTCAAAGGC GTGGACCAAG CAGAAATGGT GCCCTCCTCA 
GTGGCCAATG AAAAAATCCC ACGAATGGTA ATCCACTTCT ACGAAGAGCG CCTATCCTGG 
TACTCTGATA ATGAAGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Su(var)205 ( NM_057407.4 ) cDNA ORF clone, Drosophila melanogaster(fruit fly) -> NP_476755.1 Drosophila melanogaster suppressor of variegation 205, transcript variant A (Su(var)205), mRNA.

Price & Availability↑

CloneID	OFa14099
Clone ID Related Accession (Same CDS sequence)	NM_164799.2 , NM_057407.4
Accession Version	NM_057407.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-24
Organism	Drosophila melanogaster(fruit fly)
Product	suppressor of variegation 205, isoform A
Comment	Comment: REVIEWED REFSEQ: This record has been curated by FlyBase. This record is derived from an annotated genomic sequence (NT_033779). On Jan 16, 2013 this sequence version replaced NM_057407.3. ##Genome-Annotation-Data-START## Annotation Provider :: FlyBase Annotation Status :: Full annotation Annotation Version :: Release 6.26 URL :: http://flybase.org ##Genome-Annotation-Data-END##

ATGGGCAAGA AAATCGACAA CCCTGAGAGC TCGGCAAAGG TTTCCGATGC CGAAGAGGAG 
GAGGAGGAGT ACGCCGTGGA AAAGATCATC GACAGGCGGG TGCGCAAGGG AAAGGTGGAG 
TACTATCTGA AATGGAAGGG CTATCCCGAA ACTGAGAACA CGTGGGAGCC GGAGAACAAT 
CTCGACTGCC AGGATCTTAT CCAGCAGTAC GAGGCGAGCC GCAAGGATGA GGAGAAGTCA 
GCCGCCTCCA AGAAGGATCG ACCCAGCAGC AGCGCCAAGG CCAAGGAAAC TCAAGGACGC 
GCCAGCAGTT CGACGTCCAC AGCAAGCAAG CGAAAGTCCG AAGAACCAAC AGCGCCCTCT 
GGCAATAAAT CAAAACGTAC CACAGATGCG GAGCAGGACA CCATTCCCGT TTCAGGATCT 
ACCGGATTCG ATCGCGGCCT GGAGGCCGAA AAGATCTTGG GTGCCTCCGA CAATAATGGC 
CGCCTGACAT TCCTCATTCA GTTCAAAGGC GTGGACCAAG CAGAAATGGT GCCCTCCTCA 
GTGGCCAATG AAAAAATCCC ACGAATGGTA ATCCACTTCT ACGAAGAGCG CCTATCCTGG 
TACTCTGATA ATGAAGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_476755.1
CDS	163..783
Translation	MGKKIDNPESSAKVSDAEEEEEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKSAASKKDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAEQDTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEMVPSSVANEKIPRMVIHFYEERLSWYSDNED

Target ORF information:

RefSeq Version	NM_057407.4
Organism	Drosophila melanogaster(fruit fly)
Definition	Drosophila melanogaster suppressor of variegation 205, transcript variant A (Su(var)205), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_057407.4

ORF Insert Sequence:

ATGGGCAAGA AAATCGACAA CCCTGAGAGC TCGGCAAAGG TTTCCGATGC CGAAGAGGAG 
GAGGAGGAGT ACGCCGTGGA AAAGATCATC GACAGGCGGG TGCGCAAGGG AAAGGTGGAG 
TACTATCTGA AATGGAAGGG CTATCCCGAA ACTGAGAACA CGTGGGAGCC GGAGAACAAT 
CTCGACTGCC AGGATCTTAT CCAGCAGTAC GAGGCGAGCC GCAAGGATGA GGAGAAGTCA 
GCCGCCTCCA AGAAGGATCG ACCCAGCAGC AGCGCCAAGG CCAAGGAAAC TCAAGGACGC 
GCCAGCAGTT CGACGTCCAC AGCAAGCAAG CGAAAGTCCG AAGAACCAAC AGCGCCCTCT 
GGCAATAAAT CAAAACGTAC CACAGATGCG GAGCAGGACA CCATTCCCGT TTCAGGATCT 
ACCGGATTCG ATCGCGGCCT GGAGGCCGAA AAGATCTTGG GTGCCTCCGA CAATAATGGC 
CGCCTGACAT TCCTCATTCA GTTCAAAGGC GTGGACCAAG CAGAAATGGT GCCCTCCTCA 
GTGGCCAATG AAAAAATCCC ACGAATGGTA ATCCACTTCT ACGAAGAGCG CCTATCCTGG 
TACTCTGATA ATGAAGATTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data.
G3 (Bethesda, Md.)5(8)1721-36(2015 Jun)
Matthews BB,Dos Santos G,Crosby MA,Emmert DB,St Pierre SE,Gramates LS,Zhou P,Schroeder AJ,Falls K,Strelets V,Russo SM,Gelbart WM,

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders.
G3 (Bethesda, Md.)5(8)1737-49(2015 Jun)
Crosby MA,Gramates LS,Dos Santos G,Matthews BB,St Pierre SE,Zhou P,Schroeder AJ,Falls K,Emmert DB,Russo SM,Gelbart WM,

Sequence finishing and mapping of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1625-8(2007 Jun)
Hoskins RA,Carlson JW,Kennedy C,Acevedo D,Evans-Holm M,Frise E,Wan KH,Park S,Mendez-Lago M,Rossi F,Villasante A,Dimitri P,Karpen GH,Celniker SE

The Release 5.1 annotation of Drosophila melanogaster heterochromatin.
Science (New York, N.Y.)316(5831)1586-91(2007 Jun)
Smith CD,Shu S,Mungall CJ,Karpen GH

Combined evidence annotation of transposable elements in genome sequences.
PLoS computational biology1(2)166-75(2005 Jul)
Quesneville H,Bergman CM,Andrieu O,Autard D,Nouaud D,Ashburner M,Anxolabehere D

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

Su(var)205 cDNA ORF clone, Drosophila melanogaster(fruit fly)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報