fabp1b.1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	fabp1b.1
Entrez Gene ID	554095
Full Name	fatty acid binding protein 1b, tandem duplicate 1
Synonyms	Zf-FABP1b,fabp1b,zgc:110431
General protein information	Preferred Names fatty acid binding protein 1b, tandem duplicate 1 Names fatty acid binding protein 1-B.1 zf-FABP1b
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001024651.2	NP_001019822.1	fatty acid binding protein 1-B.1

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Subfunctionalization of peroxisome proliferator response elements accounts for retention of duplicated fabp1 genes in zebrafish.
Laprairie RB, Denovan-Wright EM, Wright JM
BMC evolutionary biology16(1)147(2016 Jul)

Divergent evolution of cis-acting peroxisome proliferator-activated receptor elements that differentially control the tandemly duplicated fatty acid-binding protein genes, fabp1b.1 and fabp1b.2, in zebrafish.
Laprairie RB, Denovan-Wright EM, Wright JM
Genome59(6)403-12(2016 Jun)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Differential regulation of the duplicated fabp1b promoters may be the result of peroxisome proliferator-activated receptors loss in fabp1b.2 during a meiotic crossing-over event.
Title: Divergent evolution of cis-acting peroxisome proliferator-activated receptor elements that differentially control the tandemly duplicated fatty acid-binding protein genes, fabp1b.1 and fabp1b.2, in zebrafish.

In vivo experiments demonstrated, for the first time, that intestinal absorption of dietary BODIPY-FLC(12) was followed by colocalization of the labeled FA with Fabp1b and Fabp2 in the nuclei.
Title: Fatty acid binding proteins have the potential to channel dietary fatty acids into enterocyte nuclei.

Data suggest that the duplicated fabp1b genes have acquired additional functions compared with the ancestral fabp1 gene, i.e., by neofunctionalization.
Title: Tandem duplication of the fabp1b gene and subsequent divergence of the tissue-specific distribution of fabp1b.1 and fabp1b.2 transcripts in zebrafish (Danio rerio).

The following fabp1b.1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the fabp1b.1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37678	NM_001024651.2 Latest version!	Danio rerio fatty acid binding protein 1b, tandem duplicate 1 (fabp1b.1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

fabp1b.1 ( NM_001024651.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001019822.1 Danio rerio fatty acid binding protein 1b, tandem duplicate 1 (fabp1b.1), mRNA.

Price & Availability↑

CloneID	ODa37678
Clone ID Related Accession (Same CDS sequence)	NM_001024651.2
Accession Version	NM_001024651.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 387bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-31
Organism	Danio rerio(zebrafish)
Product	fatty acid binding protein 1-B.1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095259.1. On Oct 2, 2014 this sequence version replaced NM_001024651.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC095259.1, DQ474062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END##

ATGTCGTTCA CTGGGAAATA TCAGCTGGAG AGTCAAGAGG GCTTCGTGGA GTTCATGAAG 
GCCGTCGGTC TTCCTGACGA CATGATTGAG AAAGGCAAAG ACATCAAGAG TGTGTCTGAG 
ATCGAGGAGA ACGGAAACCA GTTTAAAGTG ACCGTCACGA CCGGATCAAA AGTGCTGACC 
AACAGCTTCA CCATCGGGCA GGAGGCCGAC ATCGAGACGC TGACCGGAGA GAGAGTCAAG 
ACTATTGTGA ACAGAGAGGG AAATAAGCTG AAGGTGGTGC TGAACAGAAT CACATCCATC 
ACAGAGCTGG TGGACGCAAA CACACTGGTC AACACTCTGA CGCTCGGCGG CCTCGTCTAC 
AAGCGCATCA GCAAACGTGT GGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001019822.1
CDS	22..408
Translation	MSFTGKYQLESQEGFVEFMKAVGLPDDMIEKGKDIKSVSEIEENGNQFKVTVTTGSKVLTNSFTIGQEADIETLTGERVKTIVNREGNKLKVVLNRITSITELVDANTLVNTLTLGGLVYKRISKRVA

Target ORF information:

RefSeq Version	NM_001024651.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio fatty acid binding protein 1b, tandem duplicate 1 (fabp1b.1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001024651.2

ORF Insert Sequence:

ATGTCGTTCA CTGGGAAATA TCAGCTGGAG AGTCAAGAGG GCTTCGTGGA GTTCATGAAG 
GCCGTCGGTC TTCCTGACGA CATGATTGAG AAAGGCAAAG ACATCAAGAG TGTGTCTGAG 
ATCGAGGAGA ACGGAAACCA GTTTAAAGTG ACCGTCACGA CCGGATCAAA AGTGCTGACC 
AACAGCTTCA CCATCGGGCA GGAGGCCGAC ATCGAGACGC TGACCGGAGA GAGAGTCAAG 
ACTATTGTGA ACAGAGAGGG AAATAAGCTG AAGGTGGTGC TGAACAGAAT CACATCCATC 
ACAGAGCTGG TGGACGCAAA CACACTGGTC AACACTCTGA CGCTCGGCGG CCTCGTCTAC 
AAGCGCATCA GCAAACGTGT GGCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Subfunctionalization of peroxisome proliferator response elements accounts for retention of duplicated fabp1 genes in zebrafish.
BMC evolutionary biology16(1)147(2016 Jul)
Laprairie RB,Denovan-Wright EM,Wright JM

Divergent evolution of cis-acting peroxisome proliferator-activated receptor elements that differentially control the tandemly duplicated fatty acid-binding protein genes, fabp1b.1 and fabp1b.2, in zebrafish.
Genome59(6)403-12(2016 Jun)
Laprairie RB,Denovan-Wright EM,Wright JM

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

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fabp1b.1 cDNA ORF clone, Danio rerio(zebrafish)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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