lingo1b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	lingo1b
Entrez Gene ID	447837
Full Name	leucine rich repeat and Ig domain containing 1b
Synonyms	lingo1,zgc:92338
General protein information	Preferred Names leucine rich repeat and Ig domain containing 1b Names leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B leucine-rich repeat and Ig-domain containing 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005166467.3	XP_005166524.1	leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B isoform X1
XM_005166467.4	XP_005166524.1	leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B isoform X1
NM_001004576.1	NP_001004576.1	leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Effects of 2,2',4,4'-tetrabromodiphenyl ether on neurobehavior and memory change and bcl-2, c-fos, grin1b and lingo1b gene expression in male zebrafish (Danio rerio).
Zheng S, Liu C, Huang Y, Bao M, Huang Y, Wu K
Toxicology and applied pharmacology33310-16(2017 10)

Biallelic variants in LINGO1 are associated with autosomal recessive intellectual disability, microcephaly, speech and motor delay.
Ansar M, Riazuddin S, Sarwar MT, Makrythanasis P, Paracha SA, Iqbal Z, Khan J, Assir MZ, Hussain M, Razzaq A, Polla DL, Taj AS, Holmgren A, Batool N, Misceo D, Iwaszkiewicz J, de Brouwer APM, Guipponi M, Hanquinet S, Zoete V, Santoni FA, Frengen E, Ahmed J, Riazuddin S, van Bokhoven H, Antonarakis SE
Genetics in medicine : official journal of the American College of Medical Genetics(2017 Aug)

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The results of this study suggested that Lingo1b protein functions as a negative regulator of myelination and oligodendrocyte differentiation during zebrafish development.
Title: Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish.

The following lingo1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lingo1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa02015	NM_001004576.1 Latest version!	Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
ODa13380	XM_005166467.4 Latest version!	Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
View Old Accession Versions >>
ODa13380	XM_005166467.3	Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

lingo1b ( NM_001004576.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001004576.1 Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), mRNA.

Price & Availability↑

CloneID	ODa02015
Clone ID Related Accession (Same CDS sequence)	NM_001004576.1
Accession Version	NM_001004576.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1869bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Danio rerio(zebrafish)
Product	leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081651.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC081651.1, GQ983382.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168447, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END##

ATGACGTTTC TGCAGGTTAC CATCAAAATG GTGGCCAGAG AGGCAAGTGG GCACAGCTAC 
CTGGTGGCAT GCTGGCAGCC CATTCTCATT CTGATGCTGG GTACTGTGCT GTCTGGCTCT 
GCCACGGGCT GCCCCTCTCG ATGCGAGTGC AGTGCCCAGG AGCGCTCGGT CGTGTGCCAT 
CGGCGAAAGC TGATCACCCT CCCCGAGGGA ATTCCCATTG ACACGCGGCT GTTAGACCTC 
AGCAAGAACC GCTTGAAAGC CATCAACCCT GAGGAATTTC TCAACTACCC ACAACTGGAG 
GATCTACAGC TTAATGAGAA CATAATTTCC GTCATTGAAC CAGGGGCCTT CAGCAACCTC 
CTTGGCTTGC GAACGCTGGG ACTACGCAAC AATAATCTCA AGCTGATCCA GCTGGGTGTT 
TTCACTGGCC TCAGTAACCT CACTCGGTTA GACATTAGTG AGAATAAAAT TGTCATTTTG 
TTGGACTACA TGTTTCAAGA ACTCTACAAC CTGAAAGAGC TGGAGGTGGG GGATAATGAC 
CTGGTGTTCA TTTCCCACAG GGCCTTTCAT GGCCTCAGCA GCCTGGAGCA GCTTACAATG 
GAAAGATGCA ACCTGACCTC TGTGCCCACA GAGGCCTTCA GTCATCTTCA CAACTTGCTG 
ACCCTTAAGC TGCGGCATCT CAACGTCAAT GTCATTCGAG ACTTTTCCTT TAGGAGGCTC 
TATCGACTAA AAATCTTGGA GATAGCTAAC TGGCCTCTCT TAGAATCCTT GACCGCAAAG 
TCCCTGCACG GGCTGAATAT CACAACTTTG AGCATCACAA ACTGCAATCT CACTGCCGTC 
CCTTACGTGG CCATTCAACA CCTGGTGTAC CTCCGCTTTT TCAACCTGTC CTTCAATCCC 
ATTGAGGTTG TGGAGGGCAA CAAAATGCAC AATTTGCTGA GGCTCCAGGC GTTTCACTTA 
GTTGGGGGCC GGCTAGTCAG CATTGAGCCC TATTCATTCA AAGGACTCAA CTACCTTCGG 
GTTCTCAATG TATCCAGCAA TAGTCTAAGC ACTTTAGAGG AATCTGCCTT TCACTCGGTG 
GGCAACTTGG AGACTCTAGC TCTTCATGAC AACCCCCTGG CATGCGACTG TCGTCTCCTC 
TGGGTCTTTC GCCGCCGATG GAGACTTAAT TTCAACCGCC AGCAGCCATC TTGCGAAACG 
CCAGAGTTTT TGCAGGGTAA GGAGTTTAAA GACTTCCCGG ATGTTCTCCC ACCAAATTAT 
TTCACTTGTC AGAAGTCCAA GATTCGGGAT CACAAAGCCA TTCATAGATT TGTTGATGAG 
GGGACCACTG TGCAATTCCC TTGCCAAGCA GATGGAGACC CAACTCCCAT GATTATGTGG 
CAGTCTCCAA AAAAGCAATT CATCACAACT AAAAGCATCG GCCGGCTGTC TGTGTCCCTG 
GATGGCACCC TAGAGGTTAG ATATGCCCAA ATACAAGACA ATGGCACGTA CACGTGCTTT 
GCTGTCAATG CAGGAGGTAA TGACACCCGT TTGGCTCACC TACATGTTCA TAGCTACTCT 
CCCAACTGGC CCCATCAGCC CAATAAGACC TTTGCCTTTA TTTTGAACCA GCCCAGTGAT 
AACAGTGCCA ATGGGACTGG TGCGATGGAT CCCTTCCCCT TTGATATGAA GACCCTCATT 
ATTGCTACCA CCATGGGGTT TATCTCTTTC CTGGGAGTGG TCCTCTTCTG TCTGGTGCTC 
TTGTTCCTGT GGAGTCGAGG GAAAGGCAAT GCCAAGCCAA ACATTGAGAT TGAGTATGTG 
CCACGGAAAG TAGATGGAGA AAACAGCCCG AATGAGGGAT CTCACAAGAT CAGTATGAAG 
ATGATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001004576.1
CDS	294..2162
Translation	MTFLQVTIKMVAREASGHSYLVACWQPILILMLGTVLSGSATGCPSRCECSAQERSVVCHRRKLITLPEGIPIDTRLLDLSKNRLKAINPEEFLNYPQLEDLQLNENIISVIEPGAFSNLLGLRTLGLRNNNLKLIQLGVFTGLSNLTRLDISENKIVILLDYMFQELYNLKELEVGDNDLVFISHRAFHGLSSLEQLTMERCNLTSVPTEAFSHLHNLLTLKLRHLNVNVIRDFSFRRLYRLKILEIANWPLLESLTAKSLHGLNITTLSITNCNLTAVPYVAIQHLVYLRFFNLSFNPIEVVEGNKMHNLLRLQAFHLVGGRLVSIEPYSFKGLNYLRVLNVSSNSLSTLEESAFHSVGNLETLALHDNPLACDCRLLWVFRRRWRLNFNRQQPSCETPEFLQGKEFKDFPDVLPPNYFTCQKSKIRDHKAIHRFVDEGTTVQFPCQADGDPTPMIMWQSPKKQFITTKSIGRLSVSLDGTLEVRYAQIQDNGTYTCFAVNAGGNDTRLAHLHVHSYSPNWPHQPNKTFAFILNQPSDNSANGTGAMDPFPFDMKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNAKPNIEIEYVPRKVDGENSPNEGSHKISMKMI

Target ORF information:

RefSeq Version	NM_001004576.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001004576.1

ORF Insert Sequence:

ATGACGTTTC TGCAGGTTAC CATCAAAATG GTGGCCAGAG AGGCAAGTGG GCACAGCTAC 
CTGGTGGCAT GCTGGCAGCC CATTCTCATT CTGATGCTGG GTACTGTGCT GTCTGGCTCT 
GCCACGGGCT GCCCCTCTCG ATGCGAGTGC AGTGCCCAGG AGCGCTCGGT CGTGTGCCAT 
CGGCGAAAGC TGATCACCCT CCCCGAGGGA ATTCCCATTG ACACGCGGCT GTTAGACCTC 
AGCAAGAACC GCTTGAAAGC CATCAACCCT GAGGAATTTC TCAACTACCC ACAACTGGAG 
GATCTACAGC TTAATGAGAA CATAATTTCC GTCATTGAAC CAGGGGCCTT CAGCAACCTC 
CTTGGCTTGC GAACGCTGGG ACTACGCAAC AATAATCTCA AGCTGATCCA GCTGGGTGTT 
TTCACTGGCC TCAGTAACCT CACTCGGTTA GACATTAGTG AGAATAAAAT TGTCATTTTG 
TTGGACTACA TGTTTCAAGA ACTCTACAAC CTGAAAGAGC TGGAGGTGGG GGATAATGAC 
CTGGTGTTCA TTTCCCACAG GGCCTTTCAT GGCCTCAGCA GCCTGGAGCA GCTTACAATG 
GAAAGATGCA ACCTGACCTC TGTGCCCACA GAGGCCTTCA GTCATCTTCA CAACTTGCTG 
ACCCTTAAGC TGCGGCATCT CAACGTCAAT GTCATTCGAG ACTTTTCCTT TAGGAGGCTC 
TATCGACTAA AAATCTTGGA GATAGCTAAC TGGCCTCTCT TAGAATCCTT GACCGCAAAG 
TCCCTGCACG GGCTGAATAT CACAACTTTG AGCATCACAA ACTGCAATCT CACTGCCGTC 
CCTTACGTGG CCATTCAACA CCTGGTGTAC CTCCGCTTTT TCAACCTGTC CTTCAATCCC 
ATTGAGGTTG TGGAGGGCAA CAAAATGCAC AATTTGCTGA GGCTCCAGGC GTTTCACTTA 
GTTGGGGGCC GGCTAGTCAG CATTGAGCCC TATTCATTCA AAGGACTCAA CTACCTTCGG 
GTTCTCAATG TATCCAGCAA TAGTCTAAGC ACTTTAGAGG AATCTGCCTT TCACTCGGTG 
GGCAACTTGG AGACTCTAGC TCTTCATGAC AACCCCCTGG CATGCGACTG TCGTCTCCTC 
TGGGTCTTTC GCCGCCGATG GAGACTTAAT TTCAACCGCC AGCAGCCATC TTGCGAAACG 
CCAGAGTTTT TGCAGGGTAA GGAGTTTAAA GACTTCCCGG ATGTTCTCCC ACCAAATTAT 
TTCACTTGTC AGAAGTCCAA GATTCGGGAT CACAAAGCCA TTCATAGATT TGTTGATGAG 
GGGACCACTG TGCAATTCCC TTGCCAAGCA GATGGAGACC CAACTCCCAT GATTATGTGG 
CAGTCTCCAA AAAAGCAATT CATCACAACT AAAAGCATCG GCCGGCTGTC TGTGTCCCTG 
GATGGCACCC TAGAGGTTAG ATATGCCCAA ATACAAGACA ATGGCACGTA CACGTGCTTT 
GCTGTCAATG CAGGAGGTAA TGACACCCGT TTGGCTCACC TACATGTTCA TAGCTACTCT 
CCCAACTGGC CCCATCAGCC CAATAAGACC TTTGCCTTTA TTTTGAACCA GCCCAGTGAT 
AACAGTGCCA ATGGGACTGG TGCGATGGAT CCCTTCCCCT TTGATATGAA GACCCTCATT 
ATTGCTACCA CCATGGGGTT TATCTCTTTC CTGGGAGTGG TCCTCTTCTG TCTGGTGCTC 
TTGTTCCTGT GGAGTCGAGG GAAAGGCAAT GCCAAGCCAA ACATTGAGAT TGAGTATGTG 
CCACGGAAAG TAGATGGAGA AAACAGCCCG AATGAGGGAT CTCACAAGAT CAGTATGAAG 
ATGATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

lingo1b ( XM_005166467.3 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005166524.1 Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa13380
Clone ID Related Accession (Same CDS sequence)	XM_005166467.3 , XM_005166467.4
Accession Version	XM_005166467.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007118.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XM_005166467.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGTTTC TGGTTACCAT CAAAATGGTG GCCAGAGAGG CAAGTGGGCA CAGCTACCTG 
GTGGCATGCT GGCAGCCCAT TCTCATTCTG ATGCTGGGTA CTGTGCTGTC TGGCTCTGCC 
ACGGGCTGCC CCTCTCGATG CGAGTGCAGT GCCCAGGAGC GCTCGGTCGT GTGCCATCGG 
CGAAAGCTGA TCACCCTCCC CGAGGGAATT CCCATTGACA CGCGGCTGTT AGACCTCAGC 
AAGAACCGCT TGAAAGCCAT CAACCCTGAG GAATTTCTCA ACTACCCACA ACTGGAGGAT 
CTACAGCTTA ATGAGAACAT AATTTCCGTC ATTGAACCAG GGGCCTTCAG CAACCTCCTT 
GGCTTGCGAA CGCTGGGACT ACGCAACAAT AATCTCAAGC TGATCCAGCT GGGTGTTTTC 
ACTGGCCTCA GTAACCTCAC TCGGTTAGAC ATTAGTGAGA ATAAAATTGT CATTTTGTTG 
GACTACATGT TTCAAGAACT CTACAACCTG AAAGAGCTGG AGGTGGGGGA TAATGACCTG 
GTGTTCATTT CCCACAGGGC CTTTCATGGC CTCAGCAGCC TGGAGCAGCT TACAATGGAA 
AGATGCAACC TGACCTCTGT GCCCACAGAG GCCTTCAGTC ATCTTCACAA CTTGCTGACC 
CTTAAGCTGC GGCATCTCAA CGTCAATGTC ATTCGAGACT TTTCCTTTAG GAGGCTCTAT 
CGACTAAAAA TCTTGGAGAT AGCTAACTGG CCTCTCTTAG AATCCTTGAC CGCAAAGTCC 
CTGCACGGGC TGAATATCAC AACTTTGAGC ATCACAAACT GCAATCTCAC TGCCGTCCCT 
TACGTGGCCA TTCAACACCT GGTGTACCTC CGCTTTTTCA ACCTGTCCTT CAATCCCATT 
GAGGTTGTGG AGGGCAACAA AATGCACAAT TTGCTGAGGC TCCAGGCGTT TCACTTAGTT 
GGGGGCCGGC TAGTCAGCAT TGAGCCCTAT TCATTCAAAG GACTCAACTA CCTTCGGGTT 
CTCAATGTAT CCAGCAATAG TCTAAGCACT TTAGAGGAAT CTGCCTTTCA CTCGGTGGGC 
AACTTGGAGA CTCTAGCTCT TCATGACAAC CCCCTGGCAT GCGACTGTCG TCTCCTCTGG 
GTCTTTCGCC GCCGATGGAG ACTTAATTTC AACCGCCAGC AGCCATCTTG CGAAACGCCA 
GAGTTTTTGC AGGGTAAGGA GTTTAAAGAC TTCCCGGATG TTCTCCCACC AAATTATTTC 
ACTTGTCAGA AGTCCAAGAT TCGGGATCAC AAAGCCATTC ATAGATTTGT TGATGAGGGG 
ACCACTGTGC AATTCCCTTG CCAAGCAGAT GGAGACCCAA CTCCCATGAT TATGTGGCAG 
TCTCCAAAAA AGCAATTCAT CACAACTAAA AGCATCGGCC GGCTGTCTGT GTCCCTGGAT 
GGCACCCTAG AGGTTAGATA TGCCCAAATA CAAGACAATG GCACGTACAC GTGCTTTGCT 
GTCAATGCAG GAGGTAATGA CACCCGTTTG GCTCACCTAC ATGTTCATAG CTACTCTCCC 
AACTGGCCCC ATCAGCCCAA TAAGACCTTT GCCTTTATTT TGAACCAGCC CAGTGATAAC 
AGTGCCAATG GGACTGGTGC GATGGATCCC TTCCCCTTTG ATATGAAGAC CCTCATTATT 
GCTACCACCA TGGGGTTTAT CTCTTTCCTG GGAGTGGTCC TCTTCTGTCT GGTGCTCTTG 
TTCCTGTGGA GTCGAGGGAA AGGCAATGCC AAGCCAAACA TTGAGATTGA GTATGTGCCA 
CGGAAAGTAG ATGGAGAAAA CAGCCCGAAT GAGGGATCTC ACAAGATCAG TATGAAGATG 
ATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005166524.1
CDS	747..2612
Translation	MTFLVTIKMVAREASGHSYLVACWQPILILMLGTVLSGSATGCPSRCECSAQERSVVCHRRKLITLPEGIPIDTRLLDLSKNRLKAINPEEFLNYPQLEDLQLNENIISVIEPGAFSNLLGLRTLGLRNNNLKLIQLGVFTGLSNLTRLDISENKIVILLDYMFQELYNLKELEVGDNDLVFISHRAFHGLSSLEQLTMERCNLTSVPTEAFSHLHNLLTLKLRHLNVNVIRDFSFRRLYRLKILEIANWPLLESLTAKSLHGLNITTLSITNCNLTAVPYVAIQHLVYLRFFNLSFNPIEVVEGNKMHNLLRLQAFHLVGGRLVSIEPYSFKGLNYLRVLNVSSNSLSTLEESAFHSVGNLETLALHDNPLACDCRLLWVFRRRWRLNFNRQQPSCETPEFLQGKEFKDFPDVLPPNYFTCQKSKIRDHKAIHRFVDEGTTVQFPCQADGDPTPMIMWQSPKKQFITTKSIGRLSVSLDGTLEVRYAQIQDNGTYTCFAVNAGGNDTRLAHLHVHSYSPNWPHQPNKTFAFILNQPSDNSANGTGAMDPFPFDMKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNAKPNIEIEYVPRKVDGENSPNEGSHKISMKMI

Target ORF information:

RefSeq Version	XM_005166467.3
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005166467.3

ORF Insert Sequence:

ATGACGTTTC TGGTTACCAT CAAAATGGTG GCCAGAGAGG CAAGTGGGCA CAGCTACCTG 
GTGGCATGCT GGCAGCCCAT TCTCATTCTG ATGCTGGGTA CTGTGCTGTC TGGCTCTGCC 
ACGGGCTGCC CCTCTCGATG CGAGTGCAGT GCCCAGGAGC GCTCGGTCGT GTGCCATCGG 
CGAAAGCTGA TCACCCTCCC CGAGGGAATT CCCATTGACA CGCGGCTGTT AGACCTCAGC 
AAGAACCGCT TGAAAGCCAT CAACCCTGAG GAATTTCTCA ACTACCCACA ACTGGAGGAT 
CTACAGCTTA ATGAGAACAT AATTTCCGTC ATTGAACCAG GGGCCTTCAG CAACCTCCTT 
GGCTTGCGAA CGCTGGGACT ACGCAACAAT AATCTCAAGC TGATCCAGCT GGGTGTTTTC 
ACTGGCCTCA GTAACCTCAC TCGGTTAGAC ATTAGTGAGA ATAAAATTGT CATTTTGTTG 
GACTACATGT TTCAAGAACT CTACAACCTG AAAGAGCTGG AGGTGGGGGA TAATGACCTG 
GTGTTCATTT CCCACAGGGC CTTTCATGGC CTCAGCAGCC TGGAGCAGCT TACAATGGAA 
AGATGCAACC TGACCTCTGT GCCCACAGAG GCCTTCAGTC ATCTTCACAA CTTGCTGACC 
CTTAAGCTGC GGCATCTCAA CGTCAATGTC ATTCGAGACT TTTCCTTTAG GAGGCTCTAT 
CGACTAAAAA TCTTGGAGAT AGCTAACTGG CCTCTCTTAG AATCCTTGAC CGCAAAGTCC 
CTGCACGGGC TGAATATCAC AACTTTGAGC ATCACAAACT GCAATCTCAC TGCCGTCCCT 
TACGTGGCCA TTCAACACCT GGTGTACCTC CGCTTTTTCA ACCTGTCCTT CAATCCCATT 
GAGGTTGTGG AGGGCAACAA AATGCACAAT TTGCTGAGGC TCCAGGCGTT TCACTTAGTT 
GGGGGCCGGC TAGTCAGCAT TGAGCCCTAT TCATTCAAAG GACTCAACTA CCTTCGGGTT 
CTCAATGTAT CCAGCAATAG TCTAAGCACT TTAGAGGAAT CTGCCTTTCA CTCGGTGGGC 
AACTTGGAGA CTCTAGCTCT TCATGACAAC CCCCTGGCAT GCGACTGTCG TCTCCTCTGG 
GTCTTTCGCC GCCGATGGAG ACTTAATTTC AACCGCCAGC AGCCATCTTG CGAAACGCCA 
GAGTTTTTGC AGGGTAAGGA GTTTAAAGAC TTCCCGGATG TTCTCCCACC AAATTATTTC 
ACTTGTCAGA AGTCCAAGAT TCGGGATCAC AAAGCCATTC ATAGATTTGT TGATGAGGGG 
ACCACTGTGC AATTCCCTTG CCAAGCAGAT GGAGACCCAA CTCCCATGAT TATGTGGCAG 
TCTCCAAAAA AGCAATTCAT CACAACTAAA AGCATCGGCC GGCTGTCTGT GTCCCTGGAT 
GGCACCCTAG AGGTTAGATA TGCCCAAATA CAAGACAATG GCACGTACAC GTGCTTTGCT 
GTCAATGCAG GAGGTAATGA CACCCGTTTG GCTCACCTAC ATGTTCATAG CTACTCTCCC 
AACTGGCCCC ATCAGCCCAA TAAGACCTTT GCCTTTATTT TGAACCAGCC CAGTGATAAC 
AGTGCCAATG GGACTGGTGC GATGGATCCC TTCCCCTTTG ATATGAAGAC CCTCATTATT 
GCTACCACCA TGGGGTTTAT CTCTTTCCTG GGAGTGGTCC TCTTCTGTCT GGTGCTCTTG 
TTCCTGTGGA GTCGAGGGAA AGGCAATGCC AAGCCAAACA TTGAGATTGA GTATGTGCCA 
CGGAAAGTAG ATGGAGAAAA CAGCCCGAAT GAGGGATCTC ACAAGATCAG TATGAAGATG 
ATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

lingo1b ( XM_005166467.4 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_005166524.1 Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa13380
Clone ID Related Accession (Same CDS sequence)	XM_005166467.3 , XM_005166467.4
Accession Version	XM_005166467.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007118.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XM_005166467.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACGTTTC TGGTTACCAT CAAAATGGTG GCCAGAGAGG CAAGTGGGCA CAGCTACCTG 
GTGGCATGCT GGCAGCCCAT TCTCATTCTG ATGCTGGGTA CTGTGCTGTC TGGCTCTGCC 
ACGGGCTGCC CCTCTCGATG CGAGTGCAGT GCCCAGGAGC GCTCGGTCGT GTGCCATCGG 
CGAAAGCTGA TCACCCTCCC CGAGGGAATT CCCATTGACA CGCGGCTGTT AGACCTCAGC 
AAGAACCGCT TGAAAGCCAT CAACCCTGAG GAATTTCTCA ACTACCCACA ACTGGAGGAT 
CTACAGCTTA ATGAGAACAT AATTTCCGTC ATTGAACCAG GGGCCTTCAG CAACCTCCTT 
GGCTTGCGAA CGCTGGGACT ACGCAACAAT AATCTCAAGC TGATCCAGCT GGGTGTTTTC 
ACTGGCCTCA GTAACCTCAC TCGGTTAGAC ATTAGTGAGA ATAAAATTGT CATTTTGTTG 
GACTACATGT TTCAAGAACT CTACAACCTG AAAGAGCTGG AGGTGGGGGA TAATGACCTG 
GTGTTCATTT CCCACAGGGC CTTTCATGGC CTCAGCAGCC TGGAGCAGCT TACAATGGAA 
AGATGCAACC TGACCTCTGT GCCCACAGAG GCCTTCAGTC ATCTTCACAA CTTGCTGACC 
CTTAAGCTGC GGCATCTCAA CGTCAATGTC ATTCGAGACT TTTCCTTTAG GAGGCTCTAT 
CGACTAAAAA TCTTGGAGAT AGCTAACTGG CCTCTCTTAG AATCCTTGAC CGCAAAGTCC 
CTGCACGGGC TGAATATCAC AACTTTGAGC ATCACAAACT GCAATCTCAC TGCCGTCCCT 
TACGTGGCCA TTCAACACCT GGTGTACCTC CGCTTTTTCA ACCTGTCCTT CAATCCCATT 
GAGGTTGTGG AGGGCAACAA AATGCACAAT TTGCTGAGGC TCCAGGCGTT TCACTTAGTT 
GGGGGCCGGC TAGTCAGCAT TGAGCCCTAT TCATTCAAAG GACTCAACTA CCTTCGGGTT 
CTCAATGTAT CCAGCAATAG TCTAAGCACT TTAGAGGAAT CTGCCTTTCA CTCGGTGGGC 
AACTTGGAGA CTCTAGCTCT TCATGACAAC CCCCTGGCAT GCGACTGTCG TCTCCTCTGG 
GTCTTTCGCC GCCGATGGAG ACTTAATTTC AACCGCCAGC AGCCATCTTG CGAAACGCCA 
GAGTTTTTGC AGGGTAAGGA GTTTAAAGAC TTCCCGGATG TTCTCCCACC AAATTATTTC 
ACTTGTCAGA AGTCCAAGAT TCGGGATCAC AAAGCCATTC ATAGATTTGT TGATGAGGGG 
ACCACTGTGC AATTCCCTTG CCAAGCAGAT GGAGACCCAA CTCCCATGAT TATGTGGCAG 
TCTCCAAAAA AGCAATTCAT CACAACTAAA AGCATCGGCC GGCTGTCTGT GTCCCTGGAT 
GGCACCCTAG AGGTTAGATA TGCCCAAATA CAAGACAATG GCACGTACAC GTGCTTTGCT 
GTCAATGCAG GAGGTAATGA CACCCGTTTG GCTCACCTAC ATGTTCATAG CTACTCTCCC 
AACTGGCCCC ATCAGCCCAA TAAGACCTTT GCCTTTATTT TGAACCAGCC CAGTGATAAC 
AGTGCCAATG GGACTGGTGC GATGGATCCC TTCCCCTTTG ATATGAAGAC CCTCATTATT 
GCTACCACCA TGGGGTTTAT CTCTTTCCTG GGAGTGGTCC TCTTCTGTCT GGTGCTCTTG 
TTCCTGTGGA GTCGAGGGAA AGGCAATGCC AAGCCAAACA TTGAGATTGA GTATGTGCCA 
CGGAAAGTAG ATGGAGAAAA CAGCCCGAAT GAGGGATCTC ACAAGATCAG TATGAAGATG 
ATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005166524.1
CDS	746..2611
Translation	MTFLVTIKMVAREASGHSYLVACWQPILILMLGTVLSGSATGCPSRCECSAQERSVVCHRRKLITLPEGIPIDTRLLDLSKNRLKAINPEEFLNYPQLEDLQLNENIISVIEPGAFSNLLGLRTLGLRNNNLKLIQLGVFTGLSNLTRLDISENKIVILLDYMFQELYNLKELEVGDNDLVFISHRAFHGLSSLEQLTMERCNLTSVPTEAFSHLHNLLTLKLRHLNVNVIRDFSFRRLYRLKILEIANWPLLESLTAKSLHGLNITTLSITNCNLTAVPYVAIQHLVYLRFFNLSFNPIEVVEGNKMHNLLRLQAFHLVGGRLVSIEPYSFKGLNYLRVLNVSSNSLSTLEESAFHSVGNLETLALHDNPLACDCRLLWVFRRRWRLNFNRQQPSCETPEFLQGKEFKDFPDVLPPNYFTCQKSKIRDHKAIHRFVDEGTTVQFPCQADGDPTPMIMWQSPKKQFITTKSIGRLSVSLDGTLEVRYAQIQDNGTYTCFAVNAGGNDTRLAHLHVHSYSPNWPHQPNKTFAFILNQPSDNSANGTGAMDPFPFDMKTLIIATTMGFISFLGVVLFCLVLLFLWSRGKGNAKPNIEIEYVPRKVDGENSPNEGSHKISMKMI

Target ORF information:

RefSeq Version	XM_005166467.4
Organism	Danio rerio(zebrafish)
Definition	Danio rerio leucine rich repeat and Ig domain containing 1b (lingo1b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005166467.4

ORF Insert Sequence:

ATGACGTTTC TGGTTACCAT CAAAATGGTG GCCAGAGAGG CAAGTGGGCA CAGCTACCTG 
GTGGCATGCT GGCAGCCCAT TCTCATTCTG ATGCTGGGTA CTGTGCTGTC TGGCTCTGCC 
ACGGGCTGCC CCTCTCGATG CGAGTGCAGT GCCCAGGAGC GCTCGGTCGT GTGCCATCGG 
CGAAAGCTGA TCACCCTCCC CGAGGGAATT CCCATTGACA CGCGGCTGTT AGACCTCAGC 
AAGAACCGCT TGAAAGCCAT CAACCCTGAG GAATTTCTCA ACTACCCACA ACTGGAGGAT 
CTACAGCTTA ATGAGAACAT AATTTCCGTC ATTGAACCAG GGGCCTTCAG CAACCTCCTT 
GGCTTGCGAA CGCTGGGACT ACGCAACAAT AATCTCAAGC TGATCCAGCT GGGTGTTTTC 
ACTGGCCTCA GTAACCTCAC TCGGTTAGAC ATTAGTGAGA ATAAAATTGT CATTTTGTTG 
GACTACATGT TTCAAGAACT CTACAACCTG AAAGAGCTGG AGGTGGGGGA TAATGACCTG 
GTGTTCATTT CCCACAGGGC CTTTCATGGC CTCAGCAGCC TGGAGCAGCT TACAATGGAA 
AGATGCAACC TGACCTCTGT GCCCACAGAG GCCTTCAGTC ATCTTCACAA CTTGCTGACC 
CTTAAGCTGC GGCATCTCAA CGTCAATGTC ATTCGAGACT TTTCCTTTAG GAGGCTCTAT 
CGACTAAAAA TCTTGGAGAT AGCTAACTGG CCTCTCTTAG AATCCTTGAC CGCAAAGTCC 
CTGCACGGGC TGAATATCAC AACTTTGAGC ATCACAAACT GCAATCTCAC TGCCGTCCCT 
TACGTGGCCA TTCAACACCT GGTGTACCTC CGCTTTTTCA ACCTGTCCTT CAATCCCATT 
GAGGTTGTGG AGGGCAACAA AATGCACAAT TTGCTGAGGC TCCAGGCGTT TCACTTAGTT 
GGGGGCCGGC TAGTCAGCAT TGAGCCCTAT TCATTCAAAG GACTCAACTA CCTTCGGGTT 
CTCAATGTAT CCAGCAATAG TCTAAGCACT TTAGAGGAAT CTGCCTTTCA CTCGGTGGGC 
AACTTGGAGA CTCTAGCTCT TCATGACAAC CCCCTGGCAT GCGACTGTCG TCTCCTCTGG 
GTCTTTCGCC GCCGATGGAG ACTTAATTTC AACCGCCAGC AGCCATCTTG CGAAACGCCA 
GAGTTTTTGC AGGGTAAGGA GTTTAAAGAC TTCCCGGATG TTCTCCCACC AAATTATTTC 
ACTTGTCAGA AGTCCAAGAT TCGGGATCAC AAAGCCATTC ATAGATTTGT TGATGAGGGG 
ACCACTGTGC AATTCCCTTG CCAAGCAGAT GGAGACCCAA CTCCCATGAT TATGTGGCAG 
TCTCCAAAAA AGCAATTCAT CACAACTAAA AGCATCGGCC GGCTGTCTGT GTCCCTGGAT 
GGCACCCTAG AGGTTAGATA TGCCCAAATA CAAGACAATG GCACGTACAC GTGCTTTGCT 
GTCAATGCAG GAGGTAATGA CACCCGTTTG GCTCACCTAC ATGTTCATAG CTACTCTCCC 
AACTGGCCCC ATCAGCCCAA TAAGACCTTT GCCTTTATTT TGAACCAGCC CAGTGATAAC 
AGTGCCAATG GGACTGGTGC GATGGATCCC TTCCCCTTTG ATATGAAGAC CCTCATTATT 
GCTACCACCA TGGGGTTTAT CTCTTTCCTG GGAGTGGTCC TCTTCTGTCT GGTGCTCTTG 
TTCCTGTGGA GTCGAGGGAA AGGCAATGCC AAGCCAAACA TTGAGATTGA GTATGTGCCA 
CGGAAAGTAG ATGGAGAAAA CAGCCCGAAT GAGGGATCTC ACAAGATCAG TATGAAGATG 
ATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effects of 2,2',4,4'-tetrabromodiphenyl ether on neurobehavior and memory change and bcl-2, c-fos, grin1b and lingo1b gene expression in male zebrafish (Danio rerio).
Toxicology and applied pharmacology33310-16(2017 10)
Zheng S,Liu C,Huang Y,Bao M,Huang Y,Wu K

Biallelic variants in LINGO1 are associated with autosomal recessive intellectual disability, microcephaly, speech and motor delay.
Genetics in medicine : official journal of the American College of Medical Genetics(2017 Aug)
Ansar M,Riazuddin S,Sarwar MT,Makrythanasis P,Paracha SA,Iqbal Z,Khan J,Assir MZ,Hussain M,Razzaq A,Polla DL,Taj AS,Holmgren A,Batool N,Misceo D,Iwaszkiewicz J,de Brouwer APM,Guipponi M,Hanquinet S,Zoete V,Santoni FA,Frengen E,Ahmed J,Riazuddin S,van Bokhoven H,Antonarakis SE

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

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lingo1b cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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