ptpn2a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ptpn2a
Entrez Gene ID	393438
Full Name	protein tyrosine phosphatase, non-receptor type 2, a
Synonyms	PTP-1B,hm:zeh1546,ptpn2,zgc:63623
General protein information	Preferred Names protein tyrosine phosphatase, non-receptor type 2, a Names protein tyrosine phosphatase, non-receptor type 2, a protein tyrosine phosphatase 1B
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200466.2	NP_956760.2	protein tyrosine phosphatase, non-receptor type 2, a

Pathways from BioSystems

Homologies

	PTPN2	XP_001118072.2
Danio rerio (zebrafish)	ptpn2a	NP_956760.1

Gene Ontology
Bibliography

Related articles in PubMed

Differential oxidation of protein-tyrosine phosphatases during zebrafish caudal fin regeneration.
Wu W, Hale AJ, Lemeer S, den Hertog J
Scientific reports7(1)8460(2017 Aug)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos.
Dunworth WP, Cardona-Costa J, Bozkulak EC, Kim JD, Meadows S, Fischer JC, Wang Y, Cleaver O, Qyang Y, Ober EA, Jin SW
Circulation research114(1)56-66(2014 Jan)

Zebrafish as a model to study PTPs during development.
Paardekooper Overman J, den Hertog J
Methods (San Diego, Calif.)65(2)247-53(2014 Jan)

Identification and expression of the family of classical protein-tyrosine phosphatases in zebrafish.
van Eekelen M, Overvoorde J, van Rooijen C, den Hertog J
PloS one5(9)e12573(2010 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ptpn2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ptpn2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa40447	NM_200466.2 Latest version!	Danio rerio protein tyrosine phosphatase non-receptor type 2a (ptpn2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ptpn2a ( NM_200466.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_956760.2 Danio rerio protein tyrosine phosphatase non-receptor type 2a (ptpn2a), mRNA.

Price & Availability↑

CloneID	ODa40447
Clone ID Related Accession (Same CDS sequence)	NM_200466.2
Accession Version	NM_200466.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-07
Organism	Danio rerio(zebrafish)
Product	protein tyrosine phosphatase, non-receptor type 2, a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR533572.5 and CR388383.9. On Jun 19, 2015 this sequence version replaced NM_200466.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: GFIL01031788.1, BC055169.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGGACCAGG AGTTTAAGAA CATCGATTCA TCTGGAGAGT GGCAAAACCT TTATAATGAA 
TTACATAATC AGTCTCAAGA GCGGTCCTAC AAAGTGGCAA AGTTCCCAGA AAACTGCAAT 
AGGAATAGAT ATAGAGACGT CAGTCCTTAT GATCACAGTC GGGTGAAATT AGAGAATTCT 
GAGAACGACT ACATAAATGC CAGCTTAATT ACCATGGAGG AGGCTCAAAG AAGGTACATA 
TTGACACAGG GTCCCTTGAA GAACACTTGC GGTCACTTCT GGCTAATGGT TTGGGAACAG 
GGTTCCAAAG CAGTTATTAT GCTTAACAGA GTGATAGAGA AAGGCACGGA GAAATGTGCA 
CAGTACTGGC CGTCAAAAGA GGAGCAAGAC ATGAATTTCA GTGACACTGG GTTCATGGTG 
ACTCTTGTGT GTGAGGATGT TAAACCAAAT TACACAATAA GACTATTAGA ACTTCAAAAT 
GGCAAGACAG GAGAGACCAG AGATATCTAC CATTTTCATT ACACAGCATG GCCTGATTTT 
GGTGTACCAG AGTCCCCAGC ATCCTTCCTT GACTTTCTTT TCAAGGTCCG TGAGTCTGGG 
TCATTAGGGC CTGAGAATGG ACCTGTGGTG GTCCACTGCA GTGCAGGAAT AGGGCGATCT 
GGATCTTTCT CATTGGTTGA CACCTGCCTT GTCTTGATGG ACCAGAGAAA TGACTTTTTG 
GCTGTGGACA TACAAAAGGT TTTGTTAGAC ATGAGAGAGT ATCGAATGGG CCTTATTCAA 
ACCCCGGATC AACTTCGGTT TTCATATATG GCAGTCATGG AGGGAGCTAA GCTTATTCTG 
GGAGACTCTA CTTTACAGAG CTCGATCTTG AGTCCTGAGA ATTACATTGG AGAATCTGAC 
CGTATGGAAC CACAGGATTC AGGACTAGAG CAAGAATGGA AACGATTTCC AAAGGAAGAG 
CAGCTTAGTG AGTTAAAAAC ATTCAGTCTA CGAAAGAGGA GCCGCAAGGA GCGGATAGCC 
AACACAGCAC AGCAAGTGCA GAAAATGAAG ATGAAATTGA GTGATTCAGA GAAAAAGAGA 
GAAAACTGGC TGTTCTGGAG ACCAATTCTA CTTAATGTCG GCGCTGGCGC AGCTGTGGCA 
TTTGGACTTT GCATATGCTG GGCCTTTTTA ACCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_956760.2
CDS	180..1358
Translation	MDQEFKNIDSSGEWQNLYNELHNQSQERSYKVAKFPENCNRNRYRDVSPYDHSRVKLENSENDYINASLITMEEAQRRYILTQGPLKNTCGHFWLMVWEQGSKAVIMLNRVIEKGTEKCAQYWPSKEEQDMNFSDTGFMVTLVCEDVKPNYTIRLLELQNGKTGETRDIYHFHYTAWPDFGVPESPASFLDFLFKVRESGSLGPENGPVVVHCSAGIGRSGSFSLVDTCLVLMDQRNDFLAVDIQKVLLDMREYRMGLIQTPDQLRFSYMAVMEGAKLILGDSTLQSSILSPENYIGESDRMEPQDSGLEQEWKRFPKEEQLSELKTFSLRKRSRKERIANTAQQVQKMKMKLSDSEKKRENWLFWRPILLNVGAGAAVAFGLCICWAFLTQ

Target ORF information:

RefSeq Version	NM_200466.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio protein tyrosine phosphatase non-receptor type 2a (ptpn2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200466.2

ORF Insert Sequence:

ATGGACCAGG AGTTTAAGAA CATCGATTCA TCTGGAGAGT GGCAAAACCT TTATAATGAA 
TTACATAATC AGTCTCAAGA GCGGTCCTAC AAAGTGGCAA AGTTCCCAGA AAACTGCAAT 
AGGAATAGAT ATAGAGACGT CAGTCCTTAT GATCACAGTC GGGTGAAATT AGAGAATTCT 
GAGAACGACT ACATAAATGC CAGCTTAATT ACCATGGAGG AGGCTCAAAG AAGGTACATA 
TTGACACAGG GTCCCTTGAA GAACACTTGC GGTCACTTCT GGCTAATGGT TTGGGAACAG 
GGTTCCAAAG CAGTTATTAT GCTTAACAGA GTGATAGAGA AAGGCACGGA GAAATGTGCA 
CAGTACTGGC CGTCAAAAGA GGAGCAAGAC ATGAATTTCA GTGACACTGG GTTCATGGTG 
ACTCTTGTGT GTGAGGATGT TAAACCAAAT TACACAATAA GACTATTAGA ACTTCAAAAT 
GGCAAGACAG GAGAGACCAG AGATATCTAC CATTTTCATT ACACAGCATG GCCTGATTTT 
GGTGTACCAG AGTCCCCAGC ATCCTTCCTT GACTTTCTTT TCAAGGTCCG TGAGTCTGGG 
TCATTAGGGC CTGAGAATGG ACCTGTGGTG GTCCACTGCA GTGCAGGAAT AGGGCGATCT 
GGATCTTTCT CATTGGTTGA CACCTGCCTT GTCTTGATGG ACCAGAGAAA TGACTTTTTG 
GCTGTGGACA TACAAAAGGT TTTGTTAGAC ATGAGAGAGT ATCGAATGGG CCTTATTCAA 
ACCCCGGATC AACTTCGGTT TTCATATATG GCAGTCATGG AGGGAGCTAA GCTTATTCTG 
GGAGACTCTA CTTTACAGAG CTCGATCTTG AGTCCTGAGA ATTACATTGG AGAATCTGAC 
CGTATGGAAC CACAGGATTC AGGACTAGAG CAAGAATGGA AACGATTTCC AAAGGAAGAG 
CAGCTTAGTG AGTTAAAAAC ATTCAGTCTA CGAAAGAGGA GCCGCAAGGA GCGGATAGCC 
AACACAGCAC AGCAAGTGCA GAAAATGAAG ATGAAATTGA GTGATTCAGA GAAAAAGAGA 
GAAAACTGGC TGTTCTGGAG ACCAATTCTA CTTAATGTCG GCGCTGGCGC AGCTGTGGCA 
TTTGGACTTT GCATATGCTG GGCCTTTTTA ACCCAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Differential oxidation of protein-tyrosine phosphatases during zebrafish caudal fin regeneration.
Scientific reports7(1)8460(2017 Aug)
Wu W,Hale AJ,Lemeer S,den Hertog J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos.
Circulation research114(1)56-66(2014 Jan)
Dunworth WP,Cardona-Costa J,Bozkulak EC,Kim JD,Meadows S,Fischer JC,Wang Y,Cleaver O,Qyang Y,Ober EA,Jin SW

Zebrafish as a model to study PTPs during development.
Methods (San Diego, Calif.)65(2)247-53(2014 Jan)
Paardekooper Overman J,den Hertog J

Identification and expression of the family of classical protein-tyrosine phosphatases in zebrafish.
PloS one5(9)e12573(2010 Sep)
van Eekelen M,Overvoorde J,van Rooijen C,den Hertog J