selenot2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	selenot2
Entrez Gene ID	352917
Full Name	selenoprotein T, 2
Synonyms	cb699,fj34h11,selt2,sept2,wu:fj34h11,zgc:112046
General protein information	Preferred Names selenoprotein T, 2 Names selenoprotein T2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)
Summary	This gene encodes a selenoprotein, containing a selenocysteine (Sec) residue at the active site. Sec is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs in vertebrates contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is localized in the endoplasmic reticulum. It belongs to the SelWTH family that possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. Paralogs of this gene are found on chromosomes 2 (GeneID:352919) and 18 (GeneID:352921). [provided by RefSeq, Aug 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098487.2	NP_001091957.2	selenoprotein T2 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Selenoprotein Gene Nomenclature.
Gladyshev VN, Arn?r ES, Berry MJ, Brigelius-Floh? R, Bruford EA, Burk RF, Carlson BA, Castellano S, Chavatte L, Conrad M, Copeland PR, Diamond AM, Driscoll DM, Ferreiro A, Floh? L, Green FR, Guig? R, Handy DE, Hatfield DL, Hesketh J, Hoffmann PR, Holmgren A, Hondal RJ, Howard MT, Huang K, Kim HY, Kim IY, K?hrle J, Krol A, Kryukov GV, Lee BJ, Lee BC, Lei XG, Liu Q, Lescure A, Lobanov AV, Loscalzo J, Maiorino M, Mariotti M, Sandeep Prabhu K, Rayman MP, Rozovsky S, Salinas G, Schmidt EE, Schomburg L, Schweizer U, Simonovi? M, Sunde RA, Tsuji PA, Tweedie S, Ursini F, Whanger PD, Zhang Y
The Journal of biological chemistry291(46)24036-24040(2016 Nov)

Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury.
Penglase S, Hamre K, Ellingsen S
Free radical biology & medicine7595-104(2014 Oct)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following selenot2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the selenot2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa38370	NM_001098487.2 Latest version!	Danio rerio selenoprotein T, 2 (selenot2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

selenot2 ( NM_001098487.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001091957.2 Danio rerio selenoprotein T, 2 (selenot2), mRNA.

Price & Availability↑

CloneID	ODa38370
Clone ID Related Accession (Same CDS sequence)	NM_001098487.2
Accession Version	NM_001098487.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Danio rerio(zebrafish)
Product	selenoprotein T2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD285269.1 and BC065465.1. On Feb 22, 2008 this sequence version replaced NM_001098487.1. ##Evidence-Data-START## Transcript exon combination :: BC065465.1, CK028462.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGT ACAGTCAGAC GGGTATATTA ACGGCCCTGC TGCTGTTCAC AGTGGTGACT 
GTGAAGGATA TTTATGTGGG CCGCAACAGC GTGACTCAAC AGGAGAACAC TGGACCCGAC 
ATCAACACAC AGCGACAGAA TAAACACACG TTCTACACGG GACCTGTCCT CAAGTTCCAG 
TACTGTATTT CCTGAGGGTA CAGTAAGGTG TTCCAGGAGT ACTCCCGGTC TATTAGCCAG 
CTGTACCCGG ACATCCGAAT CGAGGGAGAT AATTATCCTC CCAAACCTAT CAACAAATAT 
CTCGGAAATT TCCTCTCTTA TTTTAAATTG CTTGCCATCG CTTTGATTGT GACTGGACAA 
AATCCTTTCC AAATGTTTGG AATGAACACT CCAAGAATAT GGGCCTGGGG TCAGGAGAAT 
AAGATTTTCT CCTGCCTCAT GGCCTTTTTT ATTAGTAATA TGCTGGAGAC CCATTTCCTC 
TCAACAGGAG CTTTTGAGAT TACACTGAAT GATATCCCAA TTTGGTCCAA GTTGCAATCG 
GGATATGTAC CCAACATTCA GGAGCTGTTC CAGATCTTAG ATAACCACCT TAAGATGAAT 
CAGGCCGACA AGATGAACTT TCCTTCACCG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001091957.2
CDS	122..754
Translation	MAEYSQTGILTALLLFTVVTVKDIYVGRNSVTQQENTGPDINTQRQNKHTFYTGPVLKFQYCIS*GYSKVFQEYSRSISQLYPDIRIEGDNYPPKPINKYLGNFLSYFKLLAIALIVTGQNPFQMFGMNTPRIWAWGQENKIFSCLMAFFISNMLETHFLSTGAFEITLNDIPIWSKLQSGYVPNIQELFQILDNHLKMNQADKMNFPSP

Target ORF information:

RefSeq Version	NM_001098487.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio selenoprotein T, 2 (selenot2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098487.2

ORF Insert Sequence:

ATGGCGGAGT ACAGTCAGAC GGGTATATTA ACGGCCCTGC TGCTGTTCAC AGTGGTGACT 
GTGAAGGATA TTTATGTGGG CCGCAACAGC GTGACTCAAC AGGAGAACAC TGGACCCGAC 
ATCAACACAC AGCGACAGAA TAAACACACG TTCTACACGG GACCTGTCCT CAAGTTCCAG 
TACTGTATTT CCTGAGGGTA CAGTAAGGTG TTCCAGGAGT ACTCCCGGTC TATTAGCCAG 
CTGTACCCGG ACATCCGAAT CGAGGGAGAT AATTATCCTC CCAAACCTAT CAACAAATAT 
CTCGGAAATT TCCTCTCTTA TTTTAAATTG CTTGCCATCG CTTTGATTGT GACTGGACAA 
AATCCTTTCC AAATGTTTGG AATGAACACT CCAAGAATAT GGGCCTGGGG TCAGGAGAAT 
AAGATTTTCT CCTGCCTCAT GGCCTTTTTT ATTAGTAATA TGCTGGAGAC CCATTTCCTC 
TCAACAGGAG CTTTTGAGAT TACACTGAAT GATATCCCAA TTTGGTCCAA GTTGCAATCG 
GGATATGTAC CCAACATTCA GGAGCTGTTC CAGATCTTAG ATAACCACCT TAAGATGAAT 
CAGGCCGACA AGATGAACTT TCCTTCACCG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Selenoprotein Gene Nomenclature.
The Journal of biological chemistry291(46)24036-24040(2016 Nov)
Gladyshev VN,Arn?r ES,Berry MJ,Brigelius-Floh? R,Bruford EA,Burk RF,Carlson BA,Castellano S,Chavatte L,Conrad M,Copeland PR,Diamond AM,Driscoll DM,Ferreiro A,Floh? L,Green FR,Guig? R,Handy DE,Hatfield DL,Hesketh J,Hoffmann PR,Holmgren A,Hondal RJ,Howard MT,Huang K,Kim HY,Kim IY,K?hrle J,Krol A,Kryukov GV,Lee BJ,Lee BC,Lei XG,Liu Q,Lescure A,Lobanov AV,Loscalzo J,Maiorino M,Mariotti M,Sandeep Prabhu K,Rayman MP,Rozovsky S,Salinas G,Schmidt EE,Schomburg L,Schweizer U,Simonovi? M,Sunde RA,Tsuji PA,Tweedie S,Ursini F,Whanger PD,Zhang Y

Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury.
Free radical biology & medicine7595-104(2014 Oct)
Penglase S,Hamre K,Ellingsen S

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

selenot2 cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報