selenol cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	selenol
Entrez Gene ID	100462964
Full Name	selenoprotein L
Synonyms	sell
General protein information	Preferred Names selenoprotein L Names selenoprotein L
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)
Summary	The protein encoded by this gene belongs to a subfamily of selenoprotein L (SelL), within a superfamily of thioredoxin (Trx). SelL is unusual in that it has restricted phylogenetic distribution in aquatic organisms; in vertebrates, it is found only in fish, but not in mammals, birds or amphibians. SelL proteins possess a thioredoxin-like fold, where the UxxU (U for selenocysteine) motif replaces the catalytic CxxC (C for cysteine) motif in thioredoxins, suggesting a redox function for this protein family. Unlike majority of selenoproteins, selenoprotein L contains two selenocysteine (Sec) residues encoded by UGA codons, that normally signal translation termination. The 3' UTRs of selenoprotein mRNAs in vertebrates contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. This gene uses a single SECIS element to insert both Sec residues. [provided by RefSeq, Aug 2017].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001190382.1	NP_001177311.1	selenoprotein L
NM_001190382.2	NP_001177311.1	selenoprotein L

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Characterizing the neurotranscriptomic states in alternative stress coping styles.
Wong RY, Lamm MS, Godwin J
BMC genomics16425(2015 Jun)

Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury.
Penglase S, Hamre K, Ellingsen S
Free radical biology & medicine7595-104(2014 Oct)

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

Identification and characterization of a selenoprotein family containing a diselenide bond in a redox motif.
Shchedrina VA, Novoselov SV, Malinouski MY, Gladyshev VN
Proceedings of the National Academy of Sciences of the United States of America104(35)13919-24(2007 Aug)

15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis.
Lo J, Lee S, Xu M, Liu F, Ruan H, Eun A, He Y, Ma W, Wang W, Wen Z, Peng J
Genome research13(3)455-66(2003 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following selenol gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the selenol cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ODa36359	NM_001190382.2 Latest version!	Danio rerio selenoprotein L (selenol), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
View Old Accession Versions >>
ODa36359	NM_001190382.1	Danio rerio selenoprotein L (sell), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

selenol ( NM_001190382.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001177311.1 Danio rerio selenoprotein L (sell), mRNA.

Price & Availability↑

CloneID	ODa36359
Clone ID Related Accession (Same CDS sequence)	NM_001190382.1 , NM_001190382.2
Accession Version	NM_001190382.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-12-25
Organism	Danio rerio(Zebrafish)
Product	selenoprotein L
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF999432.1, CF997926.1, CK026848.1 and CU929133.8. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 17715293 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAG TAGACGAAAG CACACTCGTA GGCGCTCTAA AAGAACTCAC TATATTTGGT 
AGAACATCGC TGGAATATGT GGAGAAAGAC ACTGCGAATG GATGTACTTT ACAAGAAGTT 
AATGGGAAAG TTCTTCCTTT ACTTGGCCTG ATGTCAGCAG GGGCAAAGTT CTGTAACAGT 
CTGGGTGTGA AAAACCAGAA GGAGGCAGAA AGTTTATGGG AACGCTTCTT TCAAAATACA 
GAGGTCCGAG AAAGTGTTGA AGGTTTACTG CAGTTGGAAG TGGAGTGGGA CCGTTTTTTG 
AAACGTTTGG ATGTTCAGAT GCAAATGAGC GACACGGTTC TTTCCCAGCA TCCTGCAGCT 
CAGACGCTCA GCTCAGATAT GCGCTTTTTA CACGTCCAAA CCAAAGAGAA TGTGTCTCTG 
GGTCAGTATT TAGGGAAAGG GGAGAATCTC CTGCTTGTGC TGCTCAGGCA TTTCGGATGA 
TTGCCATGAC GGGACCACCT GACTGAGCTG AAGAACAGCA AGATGCTTCT GGAAGCTCAG 
TCACTGCGGG TGCTGGTGGT CTCGTATGGC TCTCTTGAAG GGGCCACTTT CTGGCTCGAG 
CAGACAGGCT TTGAATTTGA CATGTTGCTG GATACAGAGA GAACGGTGTA CAAAATGTTC 
GGTCTGGGTT CATCCATGAG CAAAGTCATG AAGTTTAAGC TGATGTTCCA CTACTCTGAG 
ATTATGGCCA TGAACCGGAC GTTACCCGAA ATGCCGCCTC AGTTCATCGA GGATCTTTTT 
CAGATGGGTG GCGATTTTGT GCTGGAGCAG GATGGTAAAG TGATATTTTC CTACCGGTGT 
AAAAGCCCTG TGGACAGACC ATCCGCTACT CAGATTCTGG CCACCGTCTC TGCTCACTAT 
GCGCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001177311.1
CDS	1..909
Translation	MAEVDESTLVGALKELTIFGRTSLEYVEKDTANGCTLQEVNGKVLPLLGLMSAGAKFCNSLGVKNQKEAESLWERFFQNTEVRESVEGLLQLEVEWDRFLKRLDVQMQMSDTVLSQHPAAQTLSSDMRFLHVQTKENVSLGQYLGKGENLLLVLLRHFGLPRDHLTELKNSKMLLEAQSLRVLVVSYGSLEGATFWLEQTGFEFDMLLDTERTVYKMFGLGSSMSKVMKFKLMFHYSEIMAMNRTLPEMPPQFIEDLFQMGGDFVLEQDGKVIFSYRCKSPVDRPSATQILATVSAHYAH

Target ORF information:

RefSeq Version	NM_001190382.1
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio selenoprotein L (sell), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001190382.1

ORF Insert Sequence:

ATGGCTGAAG TAGACGAAAG CACACTCGTA GGCGCTCTAA AAGAACTCAC TATATTTGGT 
AGAACATCGC TGGAATATGT GGAGAAAGAC ACTGCGAATG GATGTACTTT ACAAGAAGTT 
AATGGGAAAG TTCTTCCTTT ACTTGGCCTG ATGTCAGCAG GGGCAAAGTT CTGTAACAGT 
CTGGGTGTGA AAAACCAGAA GGAGGCAGAA AGTTTATGGG AACGCTTCTT TCAAAATACA 
GAGGTCCGAG AAAGTGTTGA AGGTTTACTG CAGTTGGAAG TGGAGTGGGA CCGTTTTTTG 
AAACGTTTGG ATGTTCAGAT GCAAATGAGC GACACGGTTC TTTCCCAGCA TCCTGCAGCT 
CAGACGCTCA GCTCAGATAT GCGCTTTTTA CACGTCCAAA CCAAAGAGAA TGTGTCTCTG 
GGTCAGTATT TAGGGAAAGG GGAGAATCTC CTGCTTGTGC TGCTCAGGCA TTTCGGATGA 
TTGCCATGAC GGGACCACCT GACTGAGCTG AAGAACAGCA AGATGCTTCT GGAAGCTCAG 
TCACTGCGGG TGCTGGTGGT CTCGTATGGC TCTCTTGAAG GGGCCACTTT CTGGCTCGAG 
CAGACAGGCT TTGAATTTGA CATGTTGCTG GATACAGAGA GAACGGTGTA CAAAATGTTC 
GGTCTGGGTT CATCCATGAG CAAAGTCATG AAGTTTAAGC TGATGTTCCA CTACTCTGAG 
ATTATGGCCA TGAACCGGAC GTTACCCGAA ATGCCGCCTC AGTTCATCGA GGATCTTTTT 
CAGATGGGTG GCGATTTTGT GCTGGAGCAG GATGGTAAAG TGATATTTTC CTACCGGTGT 
AAAAGCCCTG TGGACAGACC ATCCGCTACT CAGATTCTGG CCACCGTCTC TGCTCACTAT 
GCGCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

selenol ( NM_001190382.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001177311.1 Danio rerio selenoprotein L (selenol), mRNA.

Price & Availability↑

CloneID	ODa36359
Clone ID Related Accession (Same CDS sequence)	NM_001190382.1 , NM_001190382.2
Accession Version	NM_001190382.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 909bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-03
Organism	Danio rerio(zebrafish)
Product	selenoprotein L
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CU929133.8. On Aug 10, 2017 this sequence version replaced NM_001190382.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: GFIL01034749.1, GDQH01022555.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## protein contains selenocysteine :: PMID: 17715293 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTGAAG TAGACGAAAG CACACTCGTA GGCGCTCTAA AAGAACTCAC TATATTTGGT 
AGAACATCGC TGGAATATGT GGAGAAAGAC ACTGCGAATG GATGTACTTT ACAAGAAGTT 
AATGGGAAAG TTCTTCCTTT ACTTGGCCTG ATGTCAGCAG GGGCAAAGTT CTGTAACAGT 
CTGGGTGTGA AAAACCAGAA GGAGGCAGAA AGTTTATGGG AACGCTTCTT TCAAAATACA 
GAGGTCCGAG AAAGTGTTGA AGGTTTACTG CAGTTGGAAG TGGAGTGGGA CCGTTTTTTG 
AAACGTTTGG ATGTTCAGAT GCAAATGAGC GACACGGTTC TTTCCCAGCA TCCTGCAGCT 
CAGACGCTCA GCTCAGATAT GCGCTTTTTA CACGTCCAAA CCAAAGAGAA TGTGTCTCTG 
GGTCAGTATT TAGGGAAAGG GGAGAATCTC CTGCTTGTGC TGCTCAGGCA TTTCGGATGA 
TTGCCATGAC GGGACCACCT GACTGAGCTG AAGAACAGCA AGATGCTTCT GGAAGCTCAG 
TCACTGCGGG TGCTGGTGGT CTCGTATGGC TCTCTTGAAG GGGCCACTTT CTGGCTCGAG 
CAGACAGGCT TTGAATTTGA CATGTTGCTG GATACAGAGA GAACGGTGTA CAAAATGTTC 
GGTCTGGGTT CATCCATGAG CAAAGTCATG AAGTTTAAGC TGATGTTCCA CTACTCTGAG 
ATTATGGCCA TGAACCGGAC GTTACCCGAA ATGCCGCCTC AGTTCATCGA GGATCTTTTT 
CAGATGGGTG GCGATTTTGT GCTGGAGCAG GATGGTAAAG TGATATTTTC CTACCGGTGT 
AAAAGCCCTG TGGACAGACC ATCCGCTACT CAGATTCTGG CCACCGTCTC TGCTCACTAT 
GCGCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001177311.1
CDS	8..916
Translation	MAEVDESTLVGALKELTIFGRTSLEYVEKDTANGCTLQEVNGKVLPLLGLMSAGAKFCNSLGVKNQKEAESLWERFFQNTEVRESVEGLLQLEVEWDRFLKRLDVQMQMSDTVLSQHPAAQTLSSDMRFLHVQTKENVSLGQYLGKGENLLLVLLRHFGLPRDHLTELKNSKMLLEAQSLRVLVVSYGSLEGATFWLEQTGFEFDMLLDTERTVYKMFGLGSSMSKVMKFKLMFHYSEIMAMNRTLPEMPPQFIEDLFQMGGDFVLEQDGKVIFSYRCKSPVDRPSATQILATVSAHYAH

Target ORF information:

RefSeq Version	NM_001190382.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio selenoprotein L (selenol), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001190382.2

ORF Insert Sequence:

ATGGCTGAAG TAGACGAAAG CACACTCGTA GGCGCTCTAA AAGAACTCAC TATATTTGGT 
AGAACATCGC TGGAATATGT GGAGAAAGAC ACTGCGAATG GATGTACTTT ACAAGAAGTT 
AATGGGAAAG TTCTTCCTTT ACTTGGCCTG ATGTCAGCAG GGGCAAAGTT CTGTAACAGT 
CTGGGTGTGA AAAACCAGAA GGAGGCAGAA AGTTTATGGG AACGCTTCTT TCAAAATACA 
GAGGTCCGAG AAAGTGTTGA AGGTTTACTG CAGTTGGAAG TGGAGTGGGA CCGTTTTTTG 
AAACGTTTGG ATGTTCAGAT GCAAATGAGC GACACGGTTC TTTCCCAGCA TCCTGCAGCT 
CAGACGCTCA GCTCAGATAT GCGCTTTTTA CACGTCCAAA CCAAAGAGAA TGTGTCTCTG 
GGTCAGTATT TAGGGAAAGG GGAGAATCTC CTGCTTGTGC TGCTCAGGCA TTTCGGATGA 
TTGCCATGAC GGGACCACCT GACTGAGCTG AAGAACAGCA AGATGCTTCT GGAAGCTCAG 
TCACTGCGGG TGCTGGTGGT CTCGTATGGC TCTCTTGAAG GGGCCACTTT CTGGCTCGAG 
CAGACAGGCT TTGAATTTGA CATGTTGCTG GATACAGAGA GAACGGTGTA CAAAATGTTC 
GGTCTGGGTT CATCCATGAG CAAAGTCATG AAGTTTAAGC TGATGTTCCA CTACTCTGAG 
ATTATGGCCA TGAACCGGAC GTTACCCGAA ATGCCGCCTC AGTTCATCGA GGATCTTTTT 
CAGATGGGTG GCGATTTTGT GCTGGAGCAG GATGGTAAAG TGATATTTTC CTACCGGTGT 
AAAAGCCCTG TGGACAGACC ATCCGCTACT CAGATTCTGG CCACCGTCTC TGCTCACTAT 
GCGCATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Characterizing the neurotranscriptomic states in alternative stress coping styles.
BMC genomics16425(2015 Jun)
Wong RY,Lamm MS,Godwin J

Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury.
Free radical biology & medicine7595-104(2014 Oct)
Penglase S,Hamre K,Ellingsen S

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

Identification and characterization of a selenoprotein family containing a diselenide bond in a redox motif.
Proceedings of the National Academy of Sciences of the United States of America104(35)13919-24(2007 Aug)
Shchedrina VA,Novoselov SV,Malinouski MY,Gladyshev VN

15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis.
Genome research13(3)455-66(2003 Mar)
Lo J,Lee S,Xu M,Liu F,Ruan H,Eun A,He Y,Ma W,Wang W,Wen Z,Peng J

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

selenol cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報