oaz2a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	oaz2a
Entrez Gene ID	100002007
Full Name	ornithine decarboxylase antizyme 2a
Synonyms	si:dkey-275p19.6
General protein information	Preferred Names ornithine decarboxylase antizyme 2a Names ornithine decarboxylase antizyme 2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)
Summary	The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. Several antizyme paralogs have been described in zebrafish. This protein shares highest similarity with antizyme 2 orthologs in other species. [provided by RefSeq, Jan 2015].

mRNA and Protein(s)

mRNA	Protein	Name
NM_001304356.1	NP_001291285.1	ornithine decarboxylase antizyme 2

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation.
Ivanov IP, Atkins JF
Nucleic acids research35(6)1842-58(2007)

Novel antizyme gene in Danio rerio expressed in brain and retina.
Ivanov IP, Pittman AJ, Chien CB, Gesteland RF, Atkins JF
Gene387(1-2)87-92(2007 Jan)

Hematopoietic gene expression profile in zebrafish kidney marrow.
Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y, Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT, Chen Z
Proceedings of the National Academy of Sciences of the United States of America101(46)16240-5(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following oaz2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the oaz2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa98448	NM_001304356.1 Latest version!	Danio rerio ornithine decarboxylase antizyme 2a (oaz2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

oaz2a ( NM_001304356.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001291285.1 Danio rerio ornithine decarboxylase antizyme 2a (oaz2a), mRNA.

Price & Availability↑

CloneID	ODa98448
Clone ID Related Accession (Same CDS sequence)	NM_001304356.1
Accession Version	NM_001304356.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 540bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-11
Organism	Danio rerio(zebrafish)
Product	ornithine decarboxylase antizyme 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EB781174.1, EB960288.1, EB885700.1 and CD602255.1. On Jan 21, 2015 this sequence version replaced XR_045172.5. ##Evidence-Data-START## Transcript exon combination :: EH508038.1, EH456742.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## ribosomal slippage :: inferred from conservation ##RefSeq-Attributes-END##

ATGTGCAACA CAGAGGAGAG TTGTGCTGTG CTGGGCTCGA GGCAGCGGGC TCCAGGGCCT 
CTGTGGTGCT CCGATGCCCC TCTCCCACTA ACGAAGATCC CGGGTGGGCG AGGGACGGGC 
AGGGATCTCC CTCACAGTGT ACTGCACAAG GACGAAAAGT TGACGGTGAC CGAGGCAGGG 
TCGGTAAGTG GAGCGCCCCC TGTCCTGCAC TTCCAGTACC AGCTGAGCGA GCGACGGATC 
TCCTCTTGGG ACACGGTTCT GTCAGACGAC GCTCTCTATC TGGAAATCCC TGCTGGTGCT 
CTTCACAATG GCAGCAGAGA AGGTTTTACC CGGCTGCTGG AGTTTGCAGA GGAGCAGTTG 
AAAGTCAGCT ATGTGTTCCT GTGGCTTCAC AAAAACAGAG ACGATCGACT GTCAATCATG 
AAGACCTTCC ACTACATGGG TTTTGAAGTG GTGAAACCGG GTCACCCGCT GGTGCCGGCT 
CGGCCCGATC TCCTCTTTAT GGTCTATTCT ATGGACAGCA GCAGTTCAGA TGAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291285.1
CDS	join(132..203,205..672)
Translation	MCNTEESCAVLGSRQRAPGPLWCSDAPLPLTKIPGGRGTGRDLPHSVLHKDEKLTVTEAGSVSGAPPVLHFQYQLSERRISSWDTVLSDDALYLEIPAGALHNGSREGFTRLLEFAEEQLKVSYVFLWLHKNRDDRLSIMKTFHYMGFEVVKPGHPLVPARPDLLFMVYSMDSSSSDEE

Target ORF information:

RefSeq Version	NM_001304356.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio ornithine decarboxylase antizyme 2a (oaz2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304356.1

ORF Insert Sequence:

ATGTGCAACA CAGAGGAGAG TTGTGCTGTG CTGGGCTCGA GGCAGCGGGC TCCAGGGCCT 
CTGTGGTGCT CCGATGCCCC TCTCCCACTA ACGAAGATCC CGGGTGGGCG AGGGACGGGC 
AGGGATCTCC CTCACAGTGT ACTGCACAAG GACGAAAAGT TGACGGTGAC CGAGGCAGGG 
TCGGTAAGTG GAGCGCCCCC TGTCCTGCAC TTCCAGTACC AGCTGAGCGA GCGACGGATC 
TCCTCTTGGG ACACGGTTCT GTCAGACGAC GCTCTCTATC TGGAAATCCC TGCTGGTGCT 
CTTCACAATG GCAGCAGAGA AGGTTTTACC CGGCTGCTGG AGTTTGCAGA GGAGCAGTTG 
AAAGTCAGCT ATGTGTTCCT GTGGCTTCAC AAAAACAGAG ACGATCGACT GTCAATCATG 
AAGACCTTCC ACTACATGGG TTTTGAAGTG GTGAAACCGG GTCACCCGCT GGTGCCGGCT 
CGGCCCGATC TCCTCTTTAT GGTCTATTCT ATGGACAGCA GCAGTTCAGA TGAAGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Ribosomal frameshifting in decoding antizyme mRNAs from yeast and protists to humans: close to 300 cases reveal remarkable diversity despite underlying conservation.
Nucleic acids research35(6)1842-58(2007)
Ivanov IP,Atkins JF

Novel antizyme gene in Danio rerio expressed in brain and retina.
Gene387(1-2)87-92(2007 Jan)
Ivanov IP,Pittman AJ,Chien CB,Gesteland RF,Atkins JF

Hematopoietic gene expression profile in zebrafish kidney marrow.
Proceedings of the National Academy of Sciences of the United States of America101(46)16240-5(2004 Nov)
Song HD,Sun XJ,Deng M,Zhang GW,Zhou Y,Wu XY,Sheng Y,Chen Y,Ruan Z,Jiang CL,Fan HY,Zon LI,Kanki JP,Liu TX,Look AT,Chen Z

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oaz2a cDNA ORF clone, Danio rerio(zebrafish)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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