Gene Symbol | ced-9 |
Entrez Gene ID | 3565776 |
Full Name | Apoptosis regulator ced-9 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » ced-9 cDNA ORF clone
Gene Symbol | ced-9 |
Entrez Gene ID | 3565776 |
Full Name | Apoptosis regulator ced-9 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_066883.6 | NP_499284.1 | Apoptosis regulator ced-9 |
NM_066883.5 | NP_499284.1 | Apoptosis regulator ced-9 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
A protein interaction cascade involving EGL-1, CED-9, CED-4, and CED-3 results in the activation of the key cell death protease CED-3, which is tightly controlled by multiple positive and negative regulators.
Title: Programmed Cell Death During Caenorhabditis elegans Development.
CED-9/Bcl-2 downregulation via LIN-35/Rb triggers germ cell apoptosis in C. elegans in response to starvation.
Title: LIN-35/Rb causes starvation-induced germ cell apoptosis via CED-9/Bcl2 downregulation in Caenorhabditis elegans.
HBx interacts directly with the B-cell lymphoma 2 (Bcl-2) homolog CED-9 (cell death abnormal) through a Bcl-2 homology 3 (BH3)-like motif to trigger both cytosolic Ca(2+) increase and cell death.
Title: Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans.
CED-9 associates with the outer mitochondrial membrane within distinct foci that do not overlap with CED-4
Title: Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction.
propose that EGL-1 converts CED-9 into a mitochondrial receptor for DRP-1, thereby shifting its activity from profusion to profission.
Title: A molecular switch that governs mitochondrial fusion and fission mediated by the BCL2-like protein CED-9 of Caenorhabditis elegans.
The following ced-9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ced-9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340147 | |
Clone ID Related Accession (Same CDS sequence) | NM_066883.6 , NM_066883.5 | |
Accession Version | NM_066883.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Apoptosis regulator ced-9 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_066883.5. COMPLETENESS: incomplete on the 5' end. |
1 | ATGACACGCT GCACGGCGGA CAACTCGCTG ACGAATCCGG CGTATCGGCG ACGAACGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499284.1 |
CDS | 1..843 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066883.6 |
1 | ATGACACGCT GCACGGCGGA CAACTCGCTG ACGAATCCGG CGTATCGGCG ACGAACGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340147 | |
Clone ID Related Accession (Same CDS sequence) | NM_066883.6 , NM_066883.5 | |
Accession Version | NM_066883.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 843bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Apoptosis regulator ced-9 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_066883.4. COMPLETENESS: incomplete on both ends. |
1 | ATGACACGCT GCACGGCGGA CAACTCGCTG ACGAATCCGG CGTATCGGCG ACGAACGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499284.1 |
CDS | 1..843 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066883.5 |
1 | ATGACACGCT GCACGGCGGA CAACTCGCTG ACGAATCCGG CGTATCGGCG ACGAACGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |