Gene Symbol | sel-10 |
Entrez Gene ID | 179878 |
Full Name | F-box/WD repeat-containing protein sel-10 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » sel-10 cDNA ORF clone
Gene Symbol | sel-10 |
Entrez Gene ID | 179878 |
Full Name | F-box/WD repeat-containing protein sel-10 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_074020.6 | NP_506421.1 | F-box/WD repeat-containing protein sel-10 |
NM_001028804.2 | NP_001023975.1 | F-box/WD repeat-containing protein sel-10 |
NM_001028804.3 | NP_001023975.1 | F-box/WD repeat-containing protein sel-10 |
NM_074020.5 | NP_506421.1 | F-box/WD repeat-containing protein sel-10 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that a second F-box protein, SEL-10, also contributes to ZYG-1 regulation. Co-depletion of LIN-23 and SEL-10 suggests these proteins function cooperatively.
Title: The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels.
Combined analysis of the SAO-1-SEL-10 protein interaction and comparisons of sao-1 and sel-10 genetic interactions suggest a possible role for SAO-1 as an accessory protein that participates with SEL-10 in downregulation of Notch signaling.
Title: Notch signaling is antagonized by SAO-1, a novel GYF-domain protein that interacts with the E3 ubiquitin ligase SEL-10 in Caenorhabditis elegans.
study found stereotyped developmental elimination of synapses in the motor neuron (HSNL) was mediated by a Skp1-cullin-F-box (SCF) complex composed of SKR-1 & SEL-10; SYG-1 bound to SKR-1 & inhibited assembly of the SCF complex, protecting nearby synapses
Title: Spatial regulation of an E3 ubiquitin ligase directs selective synapse elimination.
Results suggest that SEL-10-mediated proteolysis of FEM-1 and FEM-3 is required for normal hermaphrodite development.
Title: The Caenorhabditis elegans F-box protein SEL-10 promotes female development and may target FEM-1 and FEM-3 for degradation by the proteasome.
The following sel-10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sel-10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa345163 | |
Clone ID Related Accession (Same CDS sequence) | NM_074020.6 , NM_074020.5 | |
Accession Version | NM_074020.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1764bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | F-box/WD repeat-containing protein sel-10 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_074020.5. |
1 | ATGTGGCCAC GAAATGATGT ACACATGGAT GATGGATCGA TGACACCGGA GGACCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_506421.1 |
CDS | 5..1768 |
Translation |
Target ORF information:
Target ORF information:
|
NM_074020.6 |
1 | ATGTGGCCAC GAAATGATGT ACACATGGAT GATGGATCGA TGACACCGGA GGACCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa345163 | |
Clone ID Related Accession (Same CDS sequence) | NM_074020.6 , NM_074020.5 | |
Accession Version | NM_074020.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1764bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | F-box/WD repeat-containing protein sel-10 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_074020.4. COMPLETENESS: incomplete on both ends. |
1 | ATGTGGCCAC GAAATGATGT ACACATGGAT GATGGATCGA TGACACCGGA GGACCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_506421.1 |
CDS | 1..1764 |
Translation |
Target ORF information:
Target ORF information:
|
NM_074020.5 |
1 | ATGTGGCCAC GAAATGATGT ACACATGGAT GATGGATCGA TGACACCGGA GGACCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346461 | |
Clone ID Related Accession (Same CDS sequence) | NM_001028804.2 , NM_001028804.3 | |
Accession Version | NM_001028804.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | F-box/WD repeat-containing protein sel-10 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Jun 26, 2012 this sequence version replaced NM_001028804.1. COMPLETENESS: incomplete on both ends. |
1 | ATGTGGCCAC GAAATGATGT ACACATGGAT GATGGATCGA TGACACCGGA GGACCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023975.1 |
CDS | 1..1758 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001028804.2 |
1 | ATGTGGCCAC GAAATGATGT ACACATGGAT GATGGATCGA TGACACCGGA GGACCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa346461 | |
Clone ID Related Accession (Same CDS sequence) | NM_001028804.2 , NM_001028804.3 | |
Accession Version | NM_001028804.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | F-box/WD repeat-containing protein sel-10 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003283). On Sep 4, 2019 this sequence version replaced NM_001028804.2. |
1 | ATGTGGCCAC GAAATGATGT ACACATGGAT GATGGATCGA TGACACCGGA GGACCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001023975.1 |
CDS | 5..1762 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001028804.3 |
1 | ATGTGGCCAC GAAATGATGT ACACATGGAT GATGGATCGA TGACACCGGA GGACCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |