Gene Symbol | wrm-1 |
Entrez Gene ID | 175802 |
Full Name | Armadillo repeat-containing protein wrm-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » wrm-1 cDNA ORF clone
Gene Symbol | wrm-1 |
Entrez Gene ID | 175802 |
Full Name | Armadillo repeat-containing protein wrm-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001312927.1 | NP_001299856.1 | Armadillo repeat-containing protein wrm-1 |
NM_065835.6 | NP_498236.1 | Armadillo repeat-containing protein wrm-1 |
NM_001312927.2 | NP_001299856.1 | Armadillo repeat-containing protein wrm-1 |
NM_065835.7 | NP_498236.1 | Armadillo repeat-containing protein wrm-1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our data support a model in which WRM-1, which can undergo homotypic interaction, binds LIT-1 and thereby generates a kinase complex in which LIT-1 molecules are situated in a conformation enabling autophosphorylation.
Title: ?-Catenin-related protein WRM-1 is a multifunctional regulatory subunit of the LIT-1 MAPK complex.
model in which Wnt signaling and CDK-1 modify WRM-1 in a temporal and spatial manner to unmask an intrinsic polarity cue required for proper orientation of the endomesoderm cell division axis
Title: Wnt and CDK-1 regulate cortical release of WRM-1/?-catenin to control cell division orientation in early Caenorhabditis elegans embryos.
SYS-1 and POP-1 nuclear levels are regulated in opposite directions; the C terminus of POP-1 is essential for LIT-1 phosphorylation and is specifically bound by the diverged beta-catenin WRM-1
Title: Distinct and mutually inhibitory binding by two divergent ?-catenins coordinates TCF levels and activity in C. elegans.
Study shows that during telophase of an asymmetric division in C. elegans, extrinsic Wnt signaling modulates spindle structures through APR-1/APC, which in turn promotes asymmetrical nuclear localization of WRM-1/beta-catenin and POP-1/TCF.
Title: Wnt regulates spindle asymmetry to generate asymmetric nuclear ?-catenin in C. elegans.
Animals with reduced function of the beta-catenins SYS-1 and WRM-1 have as few as three seam cells. The 'Wnt/beta-catenin asymmetry' pathway is required for the proper stem cell-like asymmetric division of seam cells.
Title: Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development.
The following wrm-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the wrm-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340704 | |
Clone ID Related Accession (Same CDS sequence) | NM_065835.6 , NM_065835.7 | |
Accession Version | NM_065835.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2391bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Armadillo repeat-containing protein wrm-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_065835.5. COMPLETENESS: incomplete on both ends. |
1 | ATGGATGTGG ATTGCGCAGA AACATTCTCG CAACCATGCA CTCCGCTGAA TTTCAATCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498236.1 |
CDS | 1..2391 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065835.6 |
1 | ATGGATGTGG ATTGCGCAGA AACATTCTCG CAACCATGCA CTCCGCTGAA TTTCAATCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340704 | |
Clone ID Related Accession (Same CDS sequence) | NM_065835.6 , NM_065835.7 | |
Accession Version | NM_065835.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2391bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Armadillo repeat-containing protein wrm-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_065835.6. |
1 | ATGGATGTGG ATTGCGCAGA AACATTCTCG CAACCATGCA CTCCGCTGAA TTTCAATCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498236.1 |
CDS | 60..2450 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065835.7 |
1 | ATGGATGTGG ATTGCGCAGA AACATTCTCG CAACCATGCA CTCCGCTGAA TTTCAATCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341955 | |
Clone ID Related Accession (Same CDS sequence) | NM_001312927.1 , NM_001312927.2 | |
Accession Version | NM_001312927.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2229bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Armadillo repeat-containing protein wrm-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. |
1 | ATGGAACCGT CCAATTCTCG GGTGCAAGAA CTCCGGGAAG CTGCTGTGGG AAAGCGATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001299856.1 |
CDS | 1..2229 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001312927.1 |
1 | ATGGAACCGT CCAATTCTCG GGTGCAAGAA CTCCGGGAAG CTGCTGTGGG AAAGCGATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341955 | |
Clone ID Related Accession (Same CDS sequence) | NM_001312927.1 , NM_001312927.2 | |
Accession Version | NM_001312927.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2229bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Armadillo repeat-containing protein wrm-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001312927.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGGAACCGT CCAATTCTCG GGTGCAAGAA CTCCGGGAAG CTGCTGTGGG AAAGCGATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001299856.1 |
CDS | 1..2229 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001312927.2 |
1 | ATGGAACCGT CCAATTCTCG GGTGCAAGAA CTCCGGGAAG CTGCTGTGGG AAAGCGATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |