Gene Symbol | cki-2 |
Entrez Gene ID | 174261 |
Full Name | CKI family (Cyclin-dependent Kinase Inhibitor) |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » cki-2 cDNA ORF clone
Gene Symbol | cki-2 |
Entrez Gene ID | 174261 |
Full Name | CKI family (Cyclin-dependent Kinase Inhibitor) |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_063241.7 | NP_495642.3 | CKI family (Cyclin-dependent Kinase Inhibitor) |
NM_001027138.5 | NP_001022309.1 | CKI family (Cyclin-dependent Kinase Inhibitor) |
NM_063241.6 | NP_495642.3 | CKI family (Cyclin-dependent Kinase Inhibitor) |
NM_001027138.4 | NP_001022309.1 | CKI family (Cyclin-dependent Kinase Inhibitor) |
NM_001306629.1 | NP_001293558.1 | CKI family (Cyclin-dependent Kinase Inhibitor) |
NM_001306629.2 | NP_001293558.1 | CKI family (Cyclin-dependent Kinase Inhibitor) |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Here, the authors report that FBF/Pumilio, a conserved RNA-binding protein, promotes self-renewal of germline stem cells by repressing CKI-2(Cip/Kip), a Cyclin E/Cdk2 inhibitor.
Title: FBF represses the Cip/Kip cell-cycle inhibitor CKI-2 to promote self-renewal of germline stem cells in C. elegans.
Both cki-1 and cki-2 mediate cell cycle quiescence, but our genetic and phenotypic analyses demonstrate that they act within distinct pathways to exert control over the cell cycle machinery.
Title: The cyclin-dependent kinase inhibitors, cki-1 and cki-2, act in overlapping but distinct pathways to control cell cycle quiescence during C. elegans development.
This implies that the proper regulation of a cyclin E-Cdk complex by cki-2 is required for the elimination of the centrosome that occurs before or during oogenesis to ensure the assembly of a bipolar spindle in the C. elegans zygote.
Title: Cell cycle regulators control centrosome elimination during oogenesis in Caenorhabditis elegans.
The following cki-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cki-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa338204 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027138.5 , NM_001027138.4 | |
Accession Version | NM_001027138.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | CKI family (Cyclin-dependent Kinase Inhibitor) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_001027138.4. |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001022309.1 |
CDS | 145..924 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027138.5 |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338204 | |
Clone ID Related Accession (Same CDS sequence) | NM_001027138.5 , NM_001027138.4 | |
Accession Version | NM_001027138.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 780bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | CKI family (Cyclin-dependent Kinase Inhibitor) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_001027138.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001022309.1 |
CDS | 1..780 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001027138.4 |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339766 | |
Clone ID Related Accession (Same CDS sequence) | NM_063241.7 , NM_063241.6 | |
Accession Version | NM_063241.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | CKI family (Cyclin-dependent Kinase Inhibitor) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_063241.6. |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495642.3 |
CDS | 146..922 |
Translation |
Target ORF information:
Target ORF information:
|
NM_063241.7 |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339766 | |
Clone ID Related Accession (Same CDS sequence) | NM_063241.7 , NM_063241.6 | |
Accession Version | NM_063241.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | CKI family (Cyclin-dependent Kinase Inhibitor) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_063241.5. COMPLETENESS: incomplete on both ends. |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495642.3 |
CDS | 1..777 |
Translation |
Target ORF information:
Target ORF information:
|
NM_063241.6 |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339855 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306629.1 , NM_001306629.2 | |
Accession Version | NM_001306629.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | CKI family (Cyclin-dependent Kinase Inhibitor) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). COMPLETENESS: incomplete on both ends. |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293558.1 |
CDS | 1..528 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306629.1 |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339855 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306629.1 , NM_001306629.2 | |
Accession Version | NM_001306629.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | CKI family (Cyclin-dependent Kinase Inhibitor) | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_001306629.1. |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293558.1 |
CDS | 136..663 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306629.2 |
1 | ATGGCGGCAA CAACAGCCGG CGACGGGAAG CGAAAGGCGG CTAGATGTCT CTTCGGAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |