Gene Symbol | fbf-1 |
Entrez Gene ID | 174016 |
Full Name | Fem-3 mRNA-binding factor 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » fbf-1 cDNA ORF clone
Gene Symbol | fbf-1 |
Entrez Gene ID | 174016 |
Full Name | Fem-3 mRNA-binding factor 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_062815.6 | NP_495216.1 | Fem-3 mRNA-binding factor 1 |
NM_062815.7 | NP_495216.1 | Fem-3 mRNA-binding factor 1 |
Caenorhabditis elegans (roundworm) | fbf-1 | NP_495216.1 |
Caenorhabditis elegans (roundworm) | fbf-2 | NP_495220.1 |
Caenorhabditis elegans (roundworm) | puf-11 | NP_741425.1 |
Caenorhabditis elegans (roundworm) | puf-3 | NP_502606.1 |
Caenorhabditis elegans (roundworm) | puf-6 | NP_496773.1 |
Caenorhabditis elegans (roundworm) | puf-5 | NP_495814.1 |
Caenorhabditis elegans (roundworm) | puf-4 | NP_500301.1 |
Caenorhabditis elegans (roundworm) | puf-7 | NP_500820.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data indicate that a 10-amino-acid region in germline development defective-3 (GLD-3) is required for fem-3 binding factor (FBF) binding, while a 7-amino-acid loop in FBF between PUF repeats 7 and 8 is necessary for GLD-3 binding.
Title: A protein.protein interaction platform involved in recruitment of GLD-3 to the FBF.fem-3 mRNA complex.
Data show that CPB-1 (cytoplasmic polyadenylation element binding protein homolog-1) alters the affinity of FBF (fem-3 mRNA binding factor) for specific RNA sequences.
Title: Biochemical characterization of the Caenorhabditis elegans FBF.CPB-1 translational regulation complex identifies conserved protein interaction hotspots.
It was concluded that FBF1 is a key functional transition fibre component that actively facilitates the ciliary entry of assembled IFT machinery.
Title: Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes.
Here, the authors report that FBF/Pumilio, a conserved RNA-binding protein, promotes self-renewal of germline stem cells by repressing CKI-2(Cip/Kip), a Cyclin E/Cdk2 inhibitor.
Title: FBF represses the Cip/Kip cell-cycle inhibitor CKI-2 to promote self-renewal of germline stem cells in C. elegans.
The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells.
Title: The Puf RNA-binding proteins FBF-1 and FBF-2 inhibit the expression of synaptonemal complex proteins in germline stem cells.
The following fbf-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the fbf-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa339145 | |
Clone ID Related Accession (Same CDS sequence) | NM_062815.6 , NM_062815.7 | |
Accession Version | NM_062815.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1845bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Fem-3 mRNA-binding factor 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_062815.5. COMPLETENESS: incomplete on both ends. |
1 | ATGGACCAAT CAAAAATGCG CTATACAAAT CAGTTCAGAA AAACTCCGCA AAAGCCCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495216.1 |
CDS | 1..1845 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062815.6 |
1 | ATGGACCAAT CAAAAATGCG CTATACAAAT CAGTTCAGAA AAACTCCGCA AAAGCCCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339145 | |
Clone ID Related Accession (Same CDS sequence) | NM_062815.6 , NM_062815.7 | |
Accession Version | NM_062815.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1845bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Fem-3 mRNA-binding factor 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_062815.6. |
1 | ATGGACCAAT CAAAAATGCG CTATACAAAT CAGTTCAGAA AAACTCCGCA AAAGCCCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495216.1 |
CDS | 124..1968 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062815.7 |
1 | ATGGACCAAT CAAAAATGCG CTATACAAAT CAGTTCAGAA AAACTCCGCA AAAGCCCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |