Gene Symbol | FGF2 |
Entrez Gene ID | 281161 |
Full Name | fibroblast growth factor 2 |
Synonyms | BFGF,FGF-2,HBGF-2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » FGF2 cDNA ORF clone
Gene Symbol | FGF2 |
Entrez Gene ID | 281161 |
Full Name | fibroblast growth factor 2 |
Synonyms | BFGF,FGF-2,HBGF-2 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174056.4 | NP_776481.2 | fibroblast growth factor 2 precursor |
Pan troglodytes (chimpanzee) | FGF2 | NP_001103711.1 |
Canis lupus familiaris (dog) | FGF2 | XP_003432529.2 |
Homo sapiens (human) | FGF2 | NP_001997.5 |
Rattus norvegicus (Norway rat) | Fgf2 | NP_062178.1 |
Xenopus tropicalis (tropical clawed frog) | fgf2 | NP_001017333.1 |
Gallus gallus (chicken) | FGF2 | NP_990764.1 |
Danio rerio (zebrafish) | fgf2 | NP_997988.1 |
FGF2 | XP_001099284.1 | |
Bos taurus (cattle) | FGF2 | NP_776481.1 |
Mus musculus (house mouse) | Fgf2 | NP_032032.1 |
Stimulatory effects of fibroblast growth factor 2 on proliferation and migration of uterine luminal epithelial cells during early pregnancy.
Lim W, Bae H, Bazer FW, Song G
Biology of reproduction96(1)185-198(2017 01)
Staphylococcus aureus induces TGF-?1 and bFGF expression through the activation of AP-1 and NF-?B transcription factors in bovine mammary gland fibroblasts.
Wu J, Ding Y, Bi Y, Wang Y, Zhi Y, Wang J, Wang F
Microbial pathogenesis957-14(2016 Jun)
Functions and transcriptional regulation of thrombospondins and their interrelationship with fibroblast growth factor-2 in bovine luteal cells.
Farberov S, Meidan R
Biology of reproduction91(3)58(2014 Sep)
Fibroblast growth factor 2 is a key determinant of vascular sprouting during bovine luteal angiogenesis.
Woad KJ, Hunter MG, Mann GE, Laird M, Hammond AJ, Robinson RS
Reproduction (Cambridge, England)143(1)35-43(2012 Jan)
Fibroblast growth factors activate mitogen-activated protein kinase pathways to promote migration in ovine trophoblast cells.
Yang QE, Giassetti MI, Ealy AD
Reproduction (Cambridge, England)141(5)707-14(2011 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
activation of FGFR1 and FGFR2 by uterine- and endometrial-derived FGF2 stimulates PI3K/AKT and mitogen-activated protein kinase pathways for development of the porcine uterus and improvement of litter size
Title: Stimulatory effects of fibroblast growth factor 2 on proliferation and migration of uterine luminal epithelial cells during early pregnancy.
Taken together, Staphylococcus aureus induces TGF-beta1 and bFGF expression through the activation of AP-1 and NF-kappaB in bovine mammary gland fibroblasts.
Title: Staphylococcus aureus induces TGF-?1 and bFGF expression through the activation of AP-1 and NF-?B transcription factors in bovine mammary gland fibroblasts.
Data suggest THBS1 (thrombospondin-1) expression predominates in luteal endothelial cells; THBS2 expression predominates in luteinized granulosa cells. Luteinizing signals down-regulate expression of THBS1/THBS2 but up-regulate expression of FGF2.
Title: Functions and transcriptional regulation of thrombospondins and their interrelationship with fibroblast growth factor-2 in bovine luteal cells.
Mixed populations of luteal cells were treated with SU1498 (VEGF receptor 2 inhibitor) or SU5402 (FGF receptor 1 inhibitor) or control on days 0-3, 3-6 or 6-9 to determine the role of FGF2 and VEGFA during these specific windows.
Title: Fibroblast growth factor 2 is a key determinant of vascular sprouting during bovine luteal angiogenesis.
FGF2 and FGF10 regulate migratory activity of ovine trophoblast cells through MAPK-dependent pathways.
Title: Fibroblast growth factors activate mitogen-activated protein kinase pathways to promote migration in ovine trophoblast cells.
The following FGF2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGF2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa95419 | |
Clone ID Related Accession (Same CDS sequence) | NM_174056.4 | |
Accession Version | NM_174056.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 468bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-13 | |
Organism | Bos taurus(cattle) | |
Product | fibroblast growth factor 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DAAA02044761.1. On Oct 2, 2015 this sequence version replaced NM_174056.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M13440.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCGCCG GGAGCATCAC CACGCTGCCA TCCCTGCCGG AGGACGGCGG CAGCGGCGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776481.2 |
CDS | 104..571 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174056.4 |
1 | ATGGCCGCCG GGAGCATCAC CACGCTGCCA TCCCTGCCGG AGGACGGCGG CAGCGGCGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Stimulatory effects of fibroblast growth factor 2 on proliferation and migration of uterine luminal epithelial cells during early pregnancy. |
Staphylococcus aureus induces TGF-?1 and bFGF expression through the activation of AP-1 and NF-?B transcription factors in bovine mammary gland fibroblasts. |
Functions and transcriptional regulation of thrombospondins and their interrelationship with fibroblast growth factor-2 in bovine luteal cells. |
Fibroblast growth factor 2 is a key determinant of vascular sprouting during bovine luteal angiogenesis. |
Fibroblast growth factors activate mitogen-activated protein kinase pathways to promote migration in ovine trophoblast cells. |