Gene Symbol | IDN2 |
Entrez Gene ID | 824027 |
Full Name | XH/XS domain-containing protein |
Synonyms | INVOLVED IN DE NOVO 2,RDM12,RNA-DIRECTED DNA METHYLATION 12 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
ORF » Species Summary » Arabidopsis thaliana » IDN2 cDNA ORF clone
Gene Symbol | IDN2 |
Entrez Gene ID | 824027 |
Full Name | XH/XS domain-containing protein |
Synonyms | INVOLVED IN DE NOVO 2,RDM12,RNA-DIRECTED DNA METHYLATION 12 |
Gene Type | protein-coding |
Organism | Arabidopsis thaliana(thale cress) |
mRNA | Protein | Name |
---|---|---|
NM_114726.6 | NP_190436.2 | XH/XS domain-containing protein |
NM_001339377.1 | NP_001327083.1 | XH/XS domain-containing protein |
NM_202674.3 | NP_974403.1 | XH/XS domain-containing protein |
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.
Salanoubat M, Lemcke K, Rieger M, Ansorge W, Unseld M, Fartmann B, Valle G, Bl?cker H, Perez-Alonso M, Obermaier B, Delseny M, Boutry M, Grivell LA, Mache R, Puigdom?nech P, De Simone V, Choisne N, Artiguenave F, Robert C, Brottier P, Wincker P, Cattolico L, Weissenbach J, Saurin W, Qu?tier F, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, Benes V, Wurmbach E, Drzonek H, Erfle H, Jordan N, Bangert S, Wiedelmann R, Kranz H, Voss H, Holland R, Brandt P, Nyakatura G, Vezzi A, D'Angelo M, Pallavicini A, Toppo S, Simionati B, Conrad A, Hornischer K, Kauer G, L?hnert TH, Nordsiek G, Reichelt J, Scharfe M, Sch?n O, Bargues M, Terol J, Climent J, Navarro P, Collado C, Perez-Perez A, Ottenw?lder B, Duchemin D, Cooke R, Laudie M, Berger-Llauro C, Purnelle B, Masuy D, de Haan M, Maarse AC, Alcaraz JP, Cottet A, Casacuberta E, Monfort A, Argiriou A, flores M, Liguori R, Vitale D, Mannhaupt G, Haase D, Schoof H, Rudd S, Zaccaria P, Mewes HW, Mayer KF, Kaul S, Town CD, Koo HL, Tallon LJ, Jenkins J, Rooney T, Rizzo M, Walts A, Utterback T, Fujii CY, Shea TP, Creasy TH, Haas B, Maiti R, Wu D, Peterson J, Van Aken S, Pai G, Militscher J, Sellers P, Gill JE, Feldblyum TV, Preuss D, Lin X, Nierman WC, Salzberg SL, White O, Venter JC, Fraser CM, Kaneko T, Nakamura Y, Sato S, Kato T, Asamizu E, Sasamoto S, Kimura T, Idesawa K, Kawashima K, Kishida Y, Kiyokawa C, Kohara M, Matsumoto M, Matsuno A, Muraki A, Nakayama S, Nakazaki N, Shinpo S, Takeuchi C, Wada T, Watanabe A, Yamada M, Yasuda M, Tabata S, , ,
Nature408(6814)820-2(2000 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The findings support a model in which IDN2 interacts with RPA and facilitates the release of RPA from single-stranded DNA tails and subsequent recruitment of RAD51 at DSB sites to promote DSB repair.
Title: IDN2 Interacts with RPA and Facilitates DNA Double-Strand Break Repair by Homologous Recombination in Arabidopsis.
FDM1 interacts with itself and with IDN2. The XH domain of FDM1 mediates the FDM1-FDM1 and FDM1-IDN2 interactions.
Title: The DNA- and RNA-binding protein FACTOR of DNA METHYLATION 1 requires XH domain-mediated complex formation for its function in RNA-directed DNA methylation.
The paper presents a refined model for the pathway of RNA-directed DNA methylation and transcriptional gene silencing that positions function of IDN2 downstream of siRNA formation and points to an important role for its XH domain.
Title: IDN2 has a role downstream of siRNA formation in RNA-directed DNA methylation.
Data show that two partially redundant proteins termed IDN2-LIKE 1 (IDNL1; AT1G15910) and IDN2-LIKE 2 (IDNL2; AT4G00380) that are paralogous to INVOLVED IN DE NOVO 2 (IDN2) and that form a stable complex with IDN2 in vivo.
Title: INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis.
we demonstrated that the previously uncharacterized IDN2 XH domain is required for the IDN2-IDP1/IDP2 complex formation as well as for IDN2 function. IDP1 is required for de novo DNA methylation, siRNA accumulation, and transcriptional gene silencing.
Title: IDN2 and its paralogs form a complex required for RNA-directed DNA methylation.
The following IDN2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IDN2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OAb06492 | |
Clone ID Related Accession (Same CDS sequence) | NM_114726.6 , NM_001339377.1 , NM_202674.3 | |
Accession Version | NM_114726.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-13 | |
Organism | Arabidopsis thaliana(thale cress) | |
Product | XH/XS domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003074). On Sep 12, 2016 this sequence version replaced NM_114726.5. |
1 | ATGGGAAGCA CTGTGATTTT AAGCTCAGAT GATGAAGATT CAGATATTAG TGAATCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_190436.2 |
CDS | 170..2113 |
Translation |
Target ORF information:
Target ORF information:
|
NM_114726.6 |
1 | ATGGGAAGCA CTGTGATTTT AAGCTCAGAT GATGAAGATT CAGATATTAG TGAATCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OAb06492 | |
Clone ID Related Accession (Same CDS sequence) | NM_114726.6 , NM_001339377.1 , NM_202674.3 | |
Accession Version | NM_001339377.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-13 | |
Organism | Arabidopsis thaliana(thale cress) | |
Product | XH/XS domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003074). |
1 | ATGGGAAGCA CTGTGATTTT AAGCTCAGAT GATGAAGATT CAGATATTAG TGAATCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001327083.1 |
CDS | 145..2088 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001339377.1 |
1 | ATGGGAAGCA CTGTGATTTT AAGCTCAGAT GATGAAGATT CAGATATTAG TGAATCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OAb06492 | |
Clone ID Related Accession (Same CDS sequence) | NM_114726.6 , NM_001339377.1 , NM_202674.3 | |
Accession Version | NM_202674.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1944bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-13 | |
Organism | Arabidopsis thaliana(thale cress) | |
Product | XH/XS domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003074). On Apr 24, 2008 this sequence version replaced NM_202674.2. |
1 | ATGGGAAGCA CTGTGATTTT AAGCTCAGAT GATGAAGATT CAGATATTAG TGAATCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_974403.1 |
CDS | 48..1991 |
Translation |
Target ORF information:
Target ORF information:
|
NM_202674.3 |
1 | ATGGGAAGCA CTGTGATTTT AAGCTCAGAT GATGAAGATT CAGATATTAG TGAATCTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. |