EDA18 cDNA ORF clone, Arabidopsis thaliana(thale cress)

The following EDA18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EDA18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OAb08784 NM_129045.2
Latest version!
Arabidopsis thaliana RING/U-box superfamily protein (EDA18), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $342.30
$489.00
OAb36319 NM_001336534.1
Latest version!
Arabidopsis thaliana RING/U-box superfamily protein (EDA18), partial mRNA. pcDNA3.1-C-(k)DYK or customized vector 14-16 $426.30
$609.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OAb08784
    Clone ID Related Accession (Same CDS sequence) NM_129045.2
    Accession Version NM_129045.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1959bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-02-13
    Organism Arabidopsis thaliana(thale cress)
    Product RING/U-box superfamily protein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003071). On Nov 3, 2005 this sequence version replaced NM_129045.1.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGCCTCGT TACGACCTAG TTTTGGATCT GTTCTTAGAG ATCGCAACCA ACGGCACAAT 
    GACGATGTTG TTTTCAAGAA GAATCTGAAA GCTCAAGTGA AAACTGCTCC TCCGGCCATC
    TCCGACGAGA GCTCGGAGAA CAGAGTTGAT TCTTTGATCG GAAACAAGCG GAAAAAGAAC
    AATAAAAGCC GTCCTGGATC GCCGGAGAAA CCACGGACTA GAAAAGGAAA CAACTTTTCC
    GACAATCTTG GAGGAGCTTC TTCTCTTGTG CAGATATGGG AGGCGAGGCT AAATCGATCC
    AACGGCGGAA ACTCGGCTAT CCATAGCCAA TCAATAGAGA TCAGCTCAGA AGCGAGCGTT
    CAAGAAATAC ACCTTTTAGC TCCATCCATC GACGGAGAAT CTGAATCAGA GAACGAATCC
    AAGAGTCCTG ATCAGACGGT GGAGATTGAA TCTGGGACTC TCAATTCGGT TTCTGATATT
    ATCCGGAGAT TGAGTAACGA ACAGAAGCTA ACCGCCAGCA ATAATGGCGG TGCAGTCGAT
    ATGCCGATCG TTAAAACGCC GACGCTGGAG AAAAGCAGTT TTCAGGTGGT TACTTGCTCT
    CCGCGAATTC GAGGAAGGCA AGCTTACTCC GATCTGCTTG TGCATCTGGA ACGCGAACGT
    CACCGCGAAT TGGAATCACT TCTTGGACGC AACGCAGTTT CTAGGTTTCC TCAACGTGGT
    CGCCTCCAGT CAATGTTGCG GCTAAGGAGT CTCAAACGCG GCCTAGCGAT TCAAGATCGT
    CATCGTGGTA CCACAAAAAG CGATTTGAAT CGCTTCCAAC CTAGTTCTAC AATTCTCCAT
    CTAAGAGAAA AACTCCGGGA AAAAGCAGCA AACGCTGCCG CTGAAGCCGG ACTAAAGAAG
    GGTCAACAAT CCACCGTAGA AACAGAGAGC ATGCAGTCAA AAGAAACCAG TGGTATTCTT
    CATTCTCCTT CTACAGAGCG GTTAAGTCCT CAAAAACGCA ACATAGAGGA AGCAATCTTA
    CGCAAGAACG AAACTGAAAC CAAAATGAGT TACCTTCAGC TGAAAAAAGC CATAGTAGCA
    GAAGTATTGG AAAGAGAATC TGATAACACT AGTCCTCTCA CCAGCGTAAC TCCTCAAGAA
    CCGCGGATAC TAAGGAACGA GGAAGCGGGG AAACTAGAAA GCGGTACAGA GGGAACTCAA
    GAGACACCGT TCCTTGAGAC ACAAGAAATG TCATTCCAAA GCGGATGGGA AGAGCAAGAA
    GAGTATGAGG ATGAGCAGTC TTATTACGGA GACATGAGCT ATGACTGGTT TACAGAAATA
    TCTAGGCCTC GGACTTATTG GGAAGATCTG AGGAAATCTC GGTATCTGGA AGTGATGAAC
    ACTAAATCTG ACAAGGACGA TATATGCAGA CTTCTTGAGA GAAGAACGGT TTCGGGTTTC
    CTCCAAAGCG GATTACGAGA GAAGATCGAT AAGCTCATAA TGTCCCGTGT TCAGATACAT
    CCGGCTCACC GGATTGAAGA AGCAACTAAA GAGGAAGAGA AATATGACAT AGGAGAAGAA
    AAAGATGAAG ACAGAGATGA CTTGAGCCAA TCATCATCAC AGATATTTGC ACCGTCTCCG
    GCAGGATCAT GGAGTTCTCT GGACACAGGA GTTACTTCCA CACCAACGCA CAATCTTCAT
    TCCACTCTCC AACTAGAAAT GTCTGAGCTA CGAGACTCTG TCAAAACGTG TTTGGACGTC
    AATGCTAGCC TTCAAAAGTC GGTTCACCTG GAAAATCCCT TTAAACGCAA ATGCTGCGTT
    TGTAACGAAA CGCAAGTTGA AACACTTTTA TACAGGTGTG GGCACATGTG CACATGCCTG
    AGATGCGCAA ACGAACTACA ATATAATGGC GGGAAATGCC CGATTTGTCA TGCCAAGATT
    CTAGACGTTG TTCGCGTTTT CGTCGATTCA AGAACCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_181038.2
    CDS341..2299
    Translation

    Target ORF information:

    RefSeq Version NM_129045.2
    Organism Arabidopsis thaliana(thale cress)
    Definition Arabidopsis thaliana RING/U-box superfamily protein (EDA18), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_129045.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGCCTCGT TACGACCTAG TTTTGGATCT GTTCTTAGAG ATCGCAACCA ACGGCACAAT 
    GACGATGTTG TTTTCAAGAA GAATCTGAAA GCTCAAGTGA AAACTGCTCC TCCGGCCATC
    TCCGACGAGA GCTCGGAGAA CAGAGTTGAT TCTTTGATCG GAAACAAGCG GAAAAAGAAC
    AATAAAAGCC GTCCTGGATC GCCGGAGAAA CCACGGACTA GAAAAGGAAA CAACTTTTCC
    GACAATCTTG GAGGAGCTTC TTCTCTTGTG CAGATATGGG AGGCGAGGCT AAATCGATCC
    AACGGCGGAA ACTCGGCTAT CCATAGCCAA TCAATAGAGA TCAGCTCAGA AGCGAGCGTT
    CAAGAAATAC ACCTTTTAGC TCCATCCATC GACGGAGAAT CTGAATCAGA GAACGAATCC
    AAGAGTCCTG ATCAGACGGT GGAGATTGAA TCTGGGACTC TCAATTCGGT TTCTGATATT
    ATCCGGAGAT TGAGTAACGA ACAGAAGCTA ACCGCCAGCA ATAATGGCGG TGCAGTCGAT
    ATGCCGATCG TTAAAACGCC GACGCTGGAG AAAAGCAGTT TTCAGGTGGT TACTTGCTCT
    CCGCGAATTC GAGGAAGGCA AGCTTACTCC GATCTGCTTG TGCATCTGGA ACGCGAACGT
    CACCGCGAAT TGGAATCACT TCTTGGACGC AACGCAGTTT CTAGGTTTCC TCAACGTGGT
    CGCCTCCAGT CAATGTTGCG GCTAAGGAGT CTCAAACGCG GCCTAGCGAT TCAAGATCGT
    CATCGTGGTA CCACAAAAAG CGATTTGAAT CGCTTCCAAC CTAGTTCTAC AATTCTCCAT
    CTAAGAGAAA AACTCCGGGA AAAAGCAGCA AACGCTGCCG CTGAAGCCGG ACTAAAGAAG
    GGTCAACAAT CCACCGTAGA AACAGAGAGC ATGCAGTCAA AAGAAACCAG TGGTATTCTT
    CATTCTCCTT CTACAGAGCG GTTAAGTCCT CAAAAACGCA ACATAGAGGA AGCAATCTTA
    CGCAAGAACG AAACTGAAAC CAAAATGAGT TACCTTCAGC TGAAAAAAGC CATAGTAGCA
    GAAGTATTGG AAAGAGAATC TGATAACACT AGTCCTCTCA CCAGCGTAAC TCCTCAAGAA
    CCGCGGATAC TAAGGAACGA GGAAGCGGGG AAACTAGAAA GCGGTACAGA GGGAACTCAA
    GAGACACCGT TCCTTGAGAC ACAAGAAATG TCATTCCAAA GCGGATGGGA AGAGCAAGAA
    GAGTATGAGG ATGAGCAGTC TTATTACGGA GACATGAGCT ATGACTGGTT TACAGAAATA
    TCTAGGCCTC GGACTTATTG GGAAGATCTG AGGAAATCTC GGTATCTGGA AGTGATGAAC
    ACTAAATCTG ACAAGGACGA TATATGCAGA CTTCTTGAGA GAAGAACGGT TTCGGGTTTC
    CTCCAAAGCG GATTACGAGA GAAGATCGAT AAGCTCATAA TGTCCCGTGT TCAGATACAT
    CCGGCTCACC GGATTGAAGA AGCAACTAAA GAGGAAGAGA AATATGACAT AGGAGAAGAA
    AAAGATGAAG ACAGAGATGA CTTGAGCCAA TCATCATCAC AGATATTTGC ACCGTCTCCG
    GCAGGATCAT GGAGTTCTCT GGACACAGGA GTTACTTCCA CACCAACGCA CAATCTTCAT
    TCCACTCTCC AACTAGAAAT GTCTGAGCTA CGAGACTCTG TCAAAACGTG TTTGGACGTC
    AATGCTAGCC TTCAAAAGTC GGTTCACCTG GAAAATCCCT TTAAACGCAA ATGCTGCGTT
    TGTAACGAAA CGCAAGTTGA AACACTTTTA TACAGGTGTG GGCACATGTG CACATGCCTG
    AGATGCGCAA ACGAACTACA ATATAATGGC GGGAAATGCC CGATTTGTCA TGCCAAGATT
    CTAGACGTTG TTCGCGTTTT CGTCGATTCA AGAACCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OAb36319
    Clone ID Related Accession (Same CDS sequence) NM_001336534.1
    Accession Version NM_001336534.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 2001bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-02-13
    Organism Arabidopsis thaliana(thale cress)
    Product RING/U-box superfamily protein
    Comment Comment: REVIEWED REFSEQ: This record has been curated by TAIR and Araport. This record is derived from an annotated genomic sequence (NC_003071). COMPLETENESS: incomplete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    ATGGCCTCGT TACGACCTAG TTTTGGATCT GTTCTTAGAG ATCGCAACCA ACGGCACAAT 
    GACGATGTTG TTTTCAAGAA GAATCTGAAA GCTCAAGTGA AAACTGCTCC TCCGGCCATC
    TCCGACGAGA GCTCGGAGAA CAGAGTTGAT TCTTTGATCG GAAACAAGCG GAAAAAGAAC
    AATAAAAGCC GTCCTGGATC GCCGGAGAAA CCACGGACTA GAAAAGGAAA CAACTTTTCC
    GACAATCTTG GAGGAGCTTC TTCTCTTGTG CAGATATGGG AGGCGAGGCT AAATCGATCC
    AACGGCGGAA ACTCGGCTAT CCATAGCCAA TCAATAGAGA TCAGCTCAGA AGCGAGCGTT
    CAAGAAATAC ACCTTTTAGC TCCATCCATC GACGGAGAAT CTGAATCAGA GAACGAATCC
    AAGAGTCCTG ATCAGACGGT GGAGATTGAA TCTGGGACTC TCAATTCGGT TTCTGATATT
    ATCCGGAGAT TGAGTAACGA ACAGAAGCTA ACCGCCAGCA ATAATGGCGG TGCAGTCGAT
    ATGCCGATCG TTAAAACGCC GACGCTGGAG AAAAGCAGTT TTCAGGTGGT TACTTGCTCT
    CCGCGAATTC GAGGAAGGCA AGCTTACTCC GATCTGCTTG TGCATCTGGA ACGCGAACGT
    CACCGCGAAT TGGAATCACT TCTTGGACGC AACGCAGTTT CTAGGTTTCC TCAACGTGGT
    CGCCTCCAGT CAATGTTGCG GCTAAGGAGT CTCAAACGCG GCCTAGCGAT TCAAGATCGT
    CATCGTGGTA CCACAAAAAG CGATTTGAAT CGCTTCCAAC CTAGTTCTAC AATTCTCCAT
    CTAAGAGAAA AACTCCGGGA AAAAGCAGCA AACGCTGCCG CTGAAGCCGG ACTAAAGAAG
    GGTCAACAAT CCACCGTAGA AACAGAGAGC ATGCAGTCAA AAGAAACCAG TGGTATTCTT
    CATTCTCCTT CTACAGAGCG GTTAAGTCCT CAAAAACGCA ACATAGAGGA AGCAATCTTA
    CGCAAGAACG AAACTGAAAC CAAAATGAGT TACCTTCAGC TGAAAAAAGC CATAGTAGCA
    GAAGTATTGG AAAGAGAATC TGATAACACT AGTCCTCTCA CCAGCGTAAC TCCTCAAGAA
    CCGCGGATAC TAAGGAACGA GGAAGCGGGG AAACTAGAAA GCGGTACAGA GGGAACTCAA
    GAGACACCGT TCCTTGAGAC ACAAGAAATG TCATTCCAAA GCGGATGGGA AGAGCAAGAA
    GAGTATGAGG ATGAGCAGTC TTATTACGGA GACATGAGCT ATGACTGGTT TACAGAAATA
    TCTAGGCCTC GGACTTATTG GGAAGATCTG AGGAAATCTC GGTATCTGGA AGTGATGAAC
    ACTAAATCTG ACAAGGACGA TATATGCAGA CTTCTTGAGA GAAGAACGGT TTCGGGTTTC
    CTCCAAAGCG GATTACGAGA GAAGATCGAT AAGCTCATAA TGTCCCGTGT TCAGATACAT
    CCGGCTCACC GGATTGAAGA AGCAACTAAA GAGGAAGAGA AATATGACAT AGGAGAAGAA
    AAAGATGAAG ACAGAGATGA CTTGAGCCAA TCATCATCAC AGATATTTGC ACCGTCTCCG
    GCAGGATCAT GGAGTTCTCT GGACACAGGA GTTACTTCCA CACCAACGCA CAATCTTCAT
    TCCACTGAGA TGGAGATTAT AAGCGAAATG AGATCACACA TTTTACAGCT CCAACTAGAA
    ATGTCTGAGC TACGAGACTC TGTCAAAACG TGTTTGGACG TCAATGCTAG CCTTCAAAAG
    TCGGTTCACC TGGAAAATCC CTTTAAACGC AAATGCTGCG TTTGTAACGA AACGCAAGTT
    GAAACACTTT TATACAGGTG TGGGCACATG TGCACATGCC TGAGATGCGC AAACGAACTA
    CAATATAATG GCGGGAAATG CCCGATTTGT CATGCCAAGA TTCTAGACGT TGTTCGCGTT
    TTCGTCGATT CAAGAACCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001324447.1
    CDS440..2440
    Translation

    Target ORF information:

    RefSeq Version NM_001336534.1
    Organism Arabidopsis thaliana(thale cress)
    Definition Arabidopsis thaliana RING/U-box superfamily protein (EDA18), partial mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001336534.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    ATGGCCTCGT TACGACCTAG TTTTGGATCT GTTCTTAGAG ATCGCAACCA ACGGCACAAT 
    GACGATGTTG TTTTCAAGAA GAATCTGAAA GCTCAAGTGA AAACTGCTCC TCCGGCCATC
    TCCGACGAGA GCTCGGAGAA CAGAGTTGAT TCTTTGATCG GAAACAAGCG GAAAAAGAAC
    AATAAAAGCC GTCCTGGATC GCCGGAGAAA CCACGGACTA GAAAAGGAAA CAACTTTTCC
    GACAATCTTG GAGGAGCTTC TTCTCTTGTG CAGATATGGG AGGCGAGGCT AAATCGATCC
    AACGGCGGAA ACTCGGCTAT CCATAGCCAA TCAATAGAGA TCAGCTCAGA AGCGAGCGTT
    CAAGAAATAC ACCTTTTAGC TCCATCCATC GACGGAGAAT CTGAATCAGA GAACGAATCC
    AAGAGTCCTG ATCAGACGGT GGAGATTGAA TCTGGGACTC TCAATTCGGT TTCTGATATT
    ATCCGGAGAT TGAGTAACGA ACAGAAGCTA ACCGCCAGCA ATAATGGCGG TGCAGTCGAT
    ATGCCGATCG TTAAAACGCC GACGCTGGAG AAAAGCAGTT TTCAGGTGGT TACTTGCTCT
    CCGCGAATTC GAGGAAGGCA AGCTTACTCC GATCTGCTTG TGCATCTGGA ACGCGAACGT
    CACCGCGAAT TGGAATCACT TCTTGGACGC AACGCAGTTT CTAGGTTTCC TCAACGTGGT
    CGCCTCCAGT CAATGTTGCG GCTAAGGAGT CTCAAACGCG GCCTAGCGAT TCAAGATCGT
    CATCGTGGTA CCACAAAAAG CGATTTGAAT CGCTTCCAAC CTAGTTCTAC AATTCTCCAT
    CTAAGAGAAA AACTCCGGGA AAAAGCAGCA AACGCTGCCG CTGAAGCCGG ACTAAAGAAG
    GGTCAACAAT CCACCGTAGA AACAGAGAGC ATGCAGTCAA AAGAAACCAG TGGTATTCTT
    CATTCTCCTT CTACAGAGCG GTTAAGTCCT CAAAAACGCA ACATAGAGGA AGCAATCTTA
    CGCAAGAACG AAACTGAAAC CAAAATGAGT TACCTTCAGC TGAAAAAAGC CATAGTAGCA
    GAAGTATTGG AAAGAGAATC TGATAACACT AGTCCTCTCA CCAGCGTAAC TCCTCAAGAA
    CCGCGGATAC TAAGGAACGA GGAAGCGGGG AAACTAGAAA GCGGTACAGA GGGAACTCAA
    GAGACACCGT TCCTTGAGAC ACAAGAAATG TCATTCCAAA GCGGATGGGA AGAGCAAGAA
    GAGTATGAGG ATGAGCAGTC TTATTACGGA GACATGAGCT ATGACTGGTT TACAGAAATA
    TCTAGGCCTC GGACTTATTG GGAAGATCTG AGGAAATCTC GGTATCTGGA AGTGATGAAC
    ACTAAATCTG ACAAGGACGA TATATGCAGA CTTCTTGAGA GAAGAACGGT TTCGGGTTTC
    CTCCAAAGCG GATTACGAGA GAAGATCGAT AAGCTCATAA TGTCCCGTGT TCAGATACAT
    CCGGCTCACC GGATTGAAGA AGCAACTAAA GAGGAAGAGA AATATGACAT AGGAGAAGAA
    AAAGATGAAG ACAGAGATGA CTTGAGCCAA TCATCATCAC AGATATTTGC ACCGTCTCCG
    GCAGGATCAT GGAGTTCTCT GGACACAGGA GTTACTTCCA CACCAACGCA CAATCTTCAT
    TCCACTGAGA TGGAGATTAT AAGCGAAATG AGATCACACA TTTTACAGCT CCAACTAGAA
    ATGTCTGAGC TACGAGACTC TGTCAAAACG TGTTTGGACG TCAATGCTAG CCTTCAAAAG
    TCGGTTCACC TGGAAAATCC CTTTAAACGC AAATGCTGCG TTTGTAACGA AACGCAAGTT
    GAAACACTTT TATACAGGTG TGGGCACATG TGCACATGCC TGAGATGCGC AAACGAACTA
    CAATATAATG GCGGGAAATG CCCGATTTGT CATGCCAAGA TTCTAGACGT TGTTCGCGTT
    TTCGTCGATT CAAGAACCTG A

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.
    Nature402(6763)761-8(1999 Dec)
    Lin X,Kaul S,Rounsley S,Shea TP,Benito MI,Town CD,Fujii CY,Mason T,Bowman CL,Barnstead M,Feldblyum TV,Buell CR,Ketchum KA,Lee J,Ronning CM,Koo HL,Moffat KS,Cronin LA,Shen M,Pai G,Van Aken S,Umayam L,Tallon LJ,Gill JE,Adams MD,Carrera AJ,Creasy TH,Goodman HM,Somerville CR,Copenhaver GP,Preuss D,Nierman WC,White O,Eisen JA,Salzberg SL,Fraser CM,Venter JC