Gene Symbol | selenow2 |
Entrez Gene ID | 101731107 |
Full Name | selenoprotein W2 |
Synonyms | selw2,sepw2 |
Gene Type | protein-coding |
Organism | Xenopus tropicalis(tropical clawed frog) |
Summary | This gene encodes a selenoprotein containing a selenocysteine (Sec) residue, which is encoded by the UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the SelWTH family, which possesses a thioredoxin-like fold and a conserved CxxU (C is cysteine, U is Sec) motif, suggesting a redox function for this gene. A paralog of this gene is found on chromosome 8 (GeneID:100485593). [provided by RefSeq, Aug 2017]. |