lbx2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	lbx2
Entrez Gene ID	64276
Full Name	ladybird homeobox 2
Synonyms	SI:zC207O21.2,fc26c12,homeobox,lbx,lbx1,lbx1h,wu:fc26c12,zgc:92170
General protein information	Preferred Names ladybird homeobox 2 Names transcription factor LBX2 lady bird-like homeobox 1 homolog ladybird homeobox homolog 1 ladybird homeobox homolog 2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001007134.1	NP_001007135.1	transcription factor LBX2

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	lbx2	NP_001007135.1
Gallus gallus (chicken)	LBX3	NP_001038133.1

Gene Ontology
Bibliography

Related articles in PubMed

Phosphorylation of Lbx1 controls lateral myoblast migration into the limb.
Masselink W, Masaki M, Sieiro D, Marcelle C, Currie PD
Developmental biology430(2)302-309(2017 10)

BMP and retinoic acid regulate anterior-posterior patterning of the non-axial mesoderm across the dorsal-ventral axis.
Naylor RW, Skvarca LB, Thisse C, Thisse B, Hukriede NA, Davidson AJ
Nature communications712197(2016 Jul)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

controls the Wnt/beta-catenin signalling pathway in the posterior lateral and ventral mesoderm of the embryo at the gastrula stage
Title: Tissue-specific derepression of TCF/LEF controls the activity of the Wnt/?-catenin pathway.

The key noncanonical Wnt signaling components Wnt5, Dvl, and RhoA are downstream effectors involved in the regulative roles of lbx2 in convergence and extension movement and hypaxial myogenesis during zebrafish embryogenesis.
Title: Role of lbx2 in the noncanonical Wnt signaling pathway for convergence and extension movements and hypaxial myogenesis in zebrafish.

A loss of Pbx2 and Pbx4 causes a significant reduction of hindbrain and spinal cord expression of lbx1 genes.
Title: Pbx-dependent regulation of lbx gene expression in developing zebrafish embryos.

disassociation of PPL nerve extension with PLL primordial migration in some lbx2 morphants suggests that pathfinding of the PLL primordium and the lateral line nerve may be regulated independently
Title: Role of zebrafish lbx2 in embryonic lateral line development.

Results elucidate a new function of Lbx2 as a regulator of myofibril formation
Title: Lbx2 regulates formation of myofibrils.

The following lbx2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lbx2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03812	NM_001007134.1 Latest version!	Danio rerio ladybird homeobox 2 (lbx2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

lbx2 ( NM_001007134.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001007135.1 Danio rerio ladybird homeobox 2 (lbx2), mRNA.

Price & Availability↑

CloneID	ODa03812
Clone ID Related Accession (Same CDS sequence)	NM_001007134.1
Accession Version	NM_001007134.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Danio rerio(zebrafish)
Product	transcription factor LBX2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC075912.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC075912.1, AJ295165.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGACCTCCA GCTCTAAAGA CATGAAAGCA GGATCCGTTT TGCAGTCCAG CGGCGAGGAG 
AGGCGGCGGG GTCCCTTGGA CCAACTCCCA CCTCCGGCCA ACTCCAACAA GCCTCTCACC 
CCGTTCAGCA TTGAGGATAT CTTAAACAAG CCCTCCGTTA AGAAGTCCGT CGGTAGTTTG 
TGCCCTCCGC GGGTGCTGGA GAAAGTAACC GGCTCGAGCG CATCTCGGAA CGGGATCAGC 
GCCCCGTCCT CGCCGTTGTG CGCGCTGGAG GAGCTGGCGA GCAAAACATT TAAGGGTTTG 
GAAGTCAGCG TTATACAAGC AGCAGAAGGT CGTGAACACA TCAACGCCTT TGGCCAAAGA 
CAGGCATCCA AAAAACGACG GAAGTCCCGC ACAGCCTTCA CCAACCACCA AATCTACGAG 
CTGGAAAAGA GGTTTTTGTA CCAGAAATAC CTCTCACCGG CTGACAGAGA CCAGATAGCA 
CAGCAGCTGG GGCTGACCAA TGCGCAGGTC ATCACCTGGT TCCAGAACCG ACGGGCCAAG 
CTCAAGAGAG ATCTGGAGGA GATGAAGGCG GACGTAGAGT CTCTCAAGAA AATCCCACCA 
CAGGCATTGC AGAAACTGGT GTCCATGGAG GACATGGAAG ACGCTCACGG TGGCTCGGGG 
CCCATTTCTC CCAGTCTTTC CCCAAGAGCC TTTCCACAGT CCCCATCCTC GTCCAGAGGC 
CAAACCACAG ACGAGTTCTC AGAGGAGGAC GAGGAAATCG AGGTGGACGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007135.1
CDS	310..1083
Translation	MTSSSKDMKAGSVLQSSGEERRRGPLDQLPPPANSNKPLTPFSIEDILNKPSVKKSVGSLCPPRVLEKVTGSSASRNGISAPSSPLCALEELASKTFKGLEVSVIQAAEGREHINAFGQRQASKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESLKKIPPQALQKLVSMEDMEDAHGGSGPISPSLSPRAFPQSPSSSRGQTTDEFSEEDEEIEVDD

Target ORF information:

RefSeq Version	NM_001007134.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio ladybird homeobox 2 (lbx2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007134.1

ORF Insert Sequence:

ATGACCTCCA GCTCTAAAGA CATGAAAGCA GGATCCGTTT TGCAGTCCAG CGGCGAGGAG 
AGGCGGCGGG GTCCCTTGGA CCAACTCCCA CCTCCGGCCA ACTCCAACAA GCCTCTCACC 
CCGTTCAGCA TTGAGGATAT CTTAAACAAG CCCTCCGTTA AGAAGTCCGT CGGTAGTTTG 
TGCCCTCCGC GGGTGCTGGA GAAAGTAACC GGCTCGAGCG CATCTCGGAA CGGGATCAGC 
GCCCCGTCCT CGCCGTTGTG CGCGCTGGAG GAGCTGGCGA GCAAAACATT TAAGGGTTTG 
GAAGTCAGCG TTATACAAGC AGCAGAAGGT CGTGAACACA TCAACGCCTT TGGCCAAAGA 
CAGGCATCCA AAAAACGACG GAAGTCCCGC ACAGCCTTCA CCAACCACCA AATCTACGAG 
CTGGAAAAGA GGTTTTTGTA CCAGAAATAC CTCTCACCGG CTGACAGAGA CCAGATAGCA 
CAGCAGCTGG GGCTGACCAA TGCGCAGGTC ATCACCTGGT TCCAGAACCG ACGGGCCAAG 
CTCAAGAGAG ATCTGGAGGA GATGAAGGCG GACGTAGAGT CTCTCAAGAA AATCCCACCA 
CAGGCATTGC AGAAACTGGT GTCCATGGAG GACATGGAAG ACGCTCACGG TGGCTCGGGG 
CCCATTTCTC CCAGTCTTTC CCCAAGAGCC TTTCCACAGT CCCCATCCTC GTCCAGAGGC 
CAAACCACAG ACGAGTTCTC AGAGGAGGAC GAGGAAATCG AGGTGGACGA TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phosphorylation of Lbx1 controls lateral myoblast migration into the limb.
Developmental biology430(2)302-309(2017 10)
Masselink W,Masaki M,Sieiro D,Marcelle C,Currie PD

BMP and retinoic acid regulate anterior-posterior patterning of the non-axial mesoderm across the dorsal-ventral axis.
Nature communications712197(2016 Jul)
Naylor RW,Skvarca LB,Thisse C,Thisse B,Hukriede NA,Davidson AJ

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

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lbx2 cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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