creb1a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	creb1a
Entrez Gene ID	573207
Full Name	cAMP responsive element binding protein 1a
Synonyms	creb1,zgc:55598
General protein information	Preferred Names cAMP responsive element binding protein 1a Names cyclic AMP-responsive element-binding protein 1 cAMP responsive element binding protein 1
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_200909.1	NP_957203.1	cyclic AMP-responsive element-binding protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	CREB1	NP_604391.1
Canis lupus familiaris (dog)	CREB1	XP_860219.2
	CREB1	XP_001107192.1
Bos taurus (cattle)	CREB1	NP_776710.1
Rattus norvegicus (Norway rat)	Creb1	NP_112279.1
Pan troglodytes (chimpanzee)	CREB1	XP_516051.2
Mus musculus (house mouse)	Creb1	NP_034082.1
Gallus gallus (chicken)	CREB1	NP_989781.1
Danio rerio (zebrafish)	creb1a	NP_957203.1
Xenopus tropicalis (tropical clawed frog)	creb1	NP_998851.1

Gene Ontology
Bibliography

Related articles in PubMed

Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health.
Heid J, Cencioni C, Ripa R, Baumgart M, Atlante S, Milano G, Scopece A, Kuenne C, Guenther S, Azzimato V, Farsetti A, Rossi G, Braun T, Pompilio G, Martelli F, Zeiher AM, Cellerino A, Gaetano C, Spallotta F
Scientific reports7(1)16839(2017 Dec)

Graphene oxide nanosheets induce DNA damage and activate the base excision repair (BER) signaling pathway both in?vitro and in?vivo.
Lu CJ, Jiang XF, Junaid M, Ma YB, Jia PP, Wang HB, Pei DS
Chemosphere184795-805(2017 Oct)

Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules.
Lopes MW, Sapio MR, Leal RB, Fricker LD
PloS one11(4)e0152905(2016)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning
Title: CREB activity modulates neural cell proliferation, midbrain-hindbrain organization and patterning in zebrafish.

The following creb1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the creb1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa05224	NM_200909.1 Latest version!	Danio rerio cAMP responsive element binding protein 1a (creb1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

creb1a ( NM_200909.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_957203.1 Danio rerio cAMP responsive element binding protein 1a (creb1a), mRNA.

Price & Availability↑

CloneID	ODa05224
Clone ID Related Accession (Same CDS sequence)	NM_200909.1
Accession Version	NM_200909.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 957bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Danio rerio(zebrafish)
Product	cyclic AMP-responsive element-binding protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC044436.1. On Jan 9, 2008 this sequence version replaced XM_685928.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC044436.1, EH455242.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA2168446, SAMEA2168447 [ECO:0000350] ##Evidence-Data-END##

ATGACCATGG AGGCAGGAGC AGATGTCCAG CAGGGCGGCG ACACTGCGGT CTCAGAGACA 
GACACTCAGC AGATTGCCAC CTTGGCACAA GTTTCCATGG CGGCAGCACA GGCATCAGCA 
ACTGCACCCA CAGTGACCTT AGTTCAGCTG CCCAATGGGC AAACAGTGCA AGTTCACGGG 
GTCATCCAGG CAGCCCAGCC CTCTGTCATA CAATCCCCAC AGGTGCAAAC TGTACAAATT 
TCTACTATTG CTGAGAGTGA TGATTCTCAG GAGTCAGTGG ACAGTGTGAC AGATTCTCAG 
AAAAGGAGAG AGATTCTGTC TAGACGGCCC TCATACAGAA AGATCCTGAA TGACCTTTCA 
TCTGATGCTC CAGCGGTGCC ACGGATAGAA GAAGAGAAAT CAGAGGAGGA CTCCACTCCA 
GCCATAACAA CCGTTACTGT GCCAACGCCC ATCTATCAGA CAAGTAGCGG GCAATACATT 
GCTATCACTC AGGGTGGGGC GATCCAATTA GCCAATAACG GGACGGATGG AGTGCAGGGA 
CTGCAGACAC TAACCATGAC AAACGCCGCT GGAGCTCAGC CCGGCACCAC CATCCTGCAG 
TATGCACAGA CCAGTGACGG CCAGCAGATA CTTGTTCCCA GCAATCAAGT AGTGGTGCAA 
GCGGCATCAG GAGACGTTCA GGCTTATCAG ATCCGCACTG CAGCTGCGAG CACCATTGCT 
CCTGGGGTGG TCATGGCCTC TTCCCCAGCA CTGCCCAGTC AGGGAGCTGA GGAGGCCACA 
CGTAAGCGGG AAGTTCGGCT GATGAAGAAC AGGGAGGCAG CACGGGAGTG CCGCAGAAAA 
AAGAAAGAGT ATGTGAAATG TCTGGAAAAC AGAGTGGCTG TGTTGGAGAA TCAGAACAAA 
ACGCTCATCG AGGAGCTCAA AGCGCTTAAG GACCTTTACT GTCACAAATC TGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_957203.1
CDS	118..1074
Translation	MTMEAGADVQQGGDTAVSETDTQQIATLAQVSMAAAQASATAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESDDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPAVPRIEEEKSEEDSTPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAGAQPGTTILQYAQTSDGQQILVPSNQVVVQAASGDVQAYQIRTAAASTIAPGVVMASSPALPSQGAEEATRKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSE

Target ORF information:

RefSeq Version	NM_200909.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio cAMP responsive element binding protein 1a (creb1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_200909.1

ORF Insert Sequence:

ATGACCATGG AGGCAGGAGC AGATGTCCAG CAGGGCGGCG ACACTGCGGT CTCAGAGACA 
GACACTCAGC AGATTGCCAC CTTGGCACAA GTTTCCATGG CGGCAGCACA GGCATCAGCA 
ACTGCACCCA CAGTGACCTT AGTTCAGCTG CCCAATGGGC AAACAGTGCA AGTTCACGGG 
GTCATCCAGG CAGCCCAGCC CTCTGTCATA CAATCCCCAC AGGTGCAAAC TGTACAAATT 
TCTACTATTG CTGAGAGTGA TGATTCTCAG GAGTCAGTGG ACAGTGTGAC AGATTCTCAG 
AAAAGGAGAG AGATTCTGTC TAGACGGCCC TCATACAGAA AGATCCTGAA TGACCTTTCA 
TCTGATGCTC CAGCGGTGCC ACGGATAGAA GAAGAGAAAT CAGAGGAGGA CTCCACTCCA 
GCCATAACAA CCGTTACTGT GCCAACGCCC ATCTATCAGA CAAGTAGCGG GCAATACATT 
GCTATCACTC AGGGTGGGGC GATCCAATTA GCCAATAACG GGACGGATGG AGTGCAGGGA 
CTGCAGACAC TAACCATGAC AAACGCCGCT GGAGCTCAGC CCGGCACCAC CATCCTGCAG 
TATGCACAGA CCAGTGACGG CCAGCAGATA CTTGTTCCCA GCAATCAAGT AGTGGTGCAA 
GCGGCATCAG GAGACGTTCA GGCTTATCAG ATCCGCACTG CAGCTGCGAG CACCATTGCT 
CCTGGGGTGG TCATGGCCTC TTCCCCAGCA CTGCCCAGTC AGGGAGCTGA GGAGGCCACA 
CGTAAGCGGG AAGTTCGGCT GATGAAGAAC AGGGAGGCAG CACGGGAGTG CCGCAGAAAA 
AAGAAAGAGT ATGTGAAATG TCTGGAAAAC AGAGTGGCTG TGTTGGAGAA TCAGAACAAA 
ACGCTCATCG AGGAGCTCAA AGCGCTTAAG GACCTTTACT GTCACAAATC TGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health.
Scientific reports7(1)16839(2017 Dec)
Heid J,Cencioni C,Ripa R,Baumgart M,Atlante S,Milano G,Scopece A,Kuenne C,Guenther S,Azzimato V,Farsetti A,Rossi G,Braun T,Pompilio G,Martelli F,Zeiher AM,Cellerino A,Gaetano C,Spallotta F

Graphene oxide nanosheets induce DNA damage and activate the base excision repair (BER) signaling pathway both in?vitro and in?vivo.
Chemosphere184795-805(2017 Oct)
Lu CJ,Jiang XF,Junaid M,Ma YB,Jia PP,Wang HB,Pei DS

Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules.
PloS one11(4)e0152905(2016)
Lopes MW,Sapio MR,Leal RB,Fricker LD

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

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creb1a cDNA ORF clone, Danio rerio(zebrafish)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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