Gene Symbol | mev-1 |
Entrez Gene ID | 260040 |
Full Name | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » mev-1 cDNA ORF clone
Gene Symbol | mev-1 |
Entrez Gene ID | 260040 |
Full Name | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_066882.5 | NP_499283.1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
NM_001312955.1 | NP_001299884.1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
NM_066882.6 | NP_499283.1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
NM_001312955.2 | NP_001299884.1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial |
Caenorhabditis elegans (roundworm) | mev-1 | NP_499283.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_04876 | XP_003712357.1 |
Saccharomyces cerevisiae (baker's yeast) | SDH3 | NP_012781.1 |
Kluyveromyces lactis | KLLA0E12123g | XP_454496.1 |
Eremothecium gossypii | AGOS_AFR207C | NP_985754.1 |
Neurospora crassa | NCU07756 | XP_958549.1 |
Schizosaccharomyces pombe (fission yeast) | sdh3 | NP_587712.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We find that mev-1 mutants cannot respond adequately to increased energy demands, suggesting that oxidative phosphorylation is more severely impaired in these animals than has previously been appreciated.
Title: Identification of a previously undetected metabolic defect in the Complex II Caenorhabditis elegans mev-1 mutant strain using respiratory control analysis.
In conclusion, we identified PEK-1 as a mediator of hormesis in the mev-1 mutant of C. elegans which is induced by simultaneous inhibition of XBP-1 and its splicing activator IRE-1 and mediated through activation of the proteasome.
Title: PEK-1 is crucial for hormesis induced by inhibition of the IRE-1/XBP-1 pathway in the Caenorhabditis elegans mev-1 mutant.
MEV-1 as a key regulatory component for determining genetic responsiveness to oxidant/antioxidant imbalance that is associated with innate immunity
Title: Molecular mechanisms of resistance to human pathogenic bacteria in?Caenorhabditis elegans by MEV-1 mediated oxidative stress.
Increase of glucose in mev-1 mutant of C elegans reduced the lifespan of the nematodes without affecting classic markers of aging
Title: Impairment of the proteasome is crucial for glucose-induced lifespan reduction in the mev-1 mutant of Caenorhabditis elegans.
While we confirmed the ability of CED-9 to inhibit CED-4, our data argue that CED-9 can not directly inhibit CED-3.
Title: The Caenorhabditis elegans CED-9 protein does not directly inhibit the caspase CED-3, in vitro nor in yeast.
The following mev-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mev-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341843 | |
Clone ID Related Accession (Same CDS sequence) | NM_066882.5 , NM_066882.6 | |
Accession Version | NM_066882.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_066882.4. COMPLETENESS: incomplete on both ends. |
1 | ATGATTAACA TTCCAACTGC GATTCTGTGC CGCTTGGGCG CCAGATCGTC GATTTCCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499283.1 |
CDS | 1..549 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066882.5 |
1 | ATGATTAACA TTCCAACTGC GATTCTGTGC CGCTTGGGCG CCAGATCGTC GATTTCCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341843 | |
Clone ID Related Accession (Same CDS sequence) | NM_066882.5 , NM_066882.6 | |
Accession Version | NM_066882.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 549bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_066882.5. |
1 | ATGATTAACA TTCCAACTGC GATTCTGTGC CGCTTGGGCG CCAGATCGTC GATTTCCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499283.1 |
CDS | 2..550 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066882.6 |
1 | ATGATTAACA TTCCAACTGC GATTCTGTGC CGCTTGGGCG CCAGATCGTC GATTTCCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa360899 | |
Clone ID Related Accession (Same CDS sequence) | NM_001312955.1 , NM_001312955.2 | |
Accession Version | NM_001312955.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. |
1 | ATGCTCTCCG GATTCCATAG AATCAGCGGT TGTGTAATGG CCGGAACCCT TCTCGTCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001299884.1 |
CDS | 1..348 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001312955.1 |
1 | ATGCTCTCCG GATTCCATAG AATCAGCGGT TGTGTAATGG CCGGAACCCT TCTCGTCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa360899 | |
Clone ID Related Accession (Same CDS sequence) | NM_001312955.1 , NM_001312955.2 | |
Accession Version | NM_001312955.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 348bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001312955.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGCTCTCCG GATTCCATAG AATCAGCGGT TGTGTAATGG CCGGAACCCT TCTCGTCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001299884.1 |
CDS | 1..348 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001312955.2 |
1 | ATGCTCTCCG GATTCCATAG AATCAGCGGT TGTGTAATGG CCGGAACCCT TCTCGTCGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |