Gene Symbol | hlh-6 |
Entrez Gene ID | 188539 |
Full Name | Helix-loop-helix protein 6 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » hlh-6 cDNA ORF clone
Gene Symbol | hlh-6 |
Entrez Gene ID | 188539 |
Full Name | Helix-loop-helix protein 6 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_063669.1 | NP_496070.1 | Helix-loop-helix protein 6 |
NM_063669.2 | NP_496070.1 | Helix-loop-helix protein 6 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Expression of the gland-expressed genes rely on cis-elements and trans-acting factor(s) other than HLH-6 and HRL3.
Title: Transcriptional regulation of HLH-6-independent and subtype-specific genes expressed in the Caenorhabditis elegans pharyngeal glands.
Pharyngeal pumping in hlh-6 mutants is normal, but hlh-6 mutants lack expression of a class of mucin-related proteins that are normally secreted by pharyngeal glands and line the pharyngeal cuticle.
Title: The HLH-6 transcription factor regulates C. elegans pharyngeal gland development and function.
Regulation of hlh-6 by LAG-1 is strictly negative: removal of HRL1 or LAG-1 regulation results in ectopic expression of hlh-6, but does not affect expression in pharyngeal glands.
Title: The CSL transcription factor LAG-1 directly represses hlh-6 expression in C. elegans.
The experiments identified three distinct regulatory elements required for hlh-6 expression: a PHA-4-binding site and two new elements, HRL1 and HRL2 (for hlh-6 regulatory elements 1 and 2).
Title: Gland-specific expression of C. elegans hlh-6 requires the combinatorial action of three distinct promoter elements.
The following hlh-6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hlh-6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa339620 | |
Clone ID Related Accession (Same CDS sequence) | NM_063669.1 , NM_063669.2 | |
Accession Version | NM_063669.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Helix-loop-helix protein 6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). COMPLETENESS: incomplete on both ends. |
1 | ATGTCAATTT CCCAAAACAA CTTTTTGACC ATGTTCCCTG TAACTTATAC ATTTGAGAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_496070.1 |
CDS | 1..807 |
Translation |
Target ORF information:
Target ORF information:
|
NM_063669.1 |
1 | ATGTCAATTT CCCAAAACAA CTTTTTGACC ATGTTCCCTG TAACTTATAC ATTTGAGAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339620 | |
Clone ID Related Accession (Same CDS sequence) | NM_063669.1 , NM_063669.2 | |
Accession Version | NM_063669.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 807bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Helix-loop-helix protein 6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_063669.1. |
1 | ATGTCAATTT CCCAAAACAA CTTTTTGACC ATGTTCCCTG TAACTTATAC ATTTGAGAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_496070.1 |
CDS | 17..823 |
Translation |
Target ORF information:
Target ORF information:
|
NM_063669.2 |
1 | ATGTCAATTT CCCAAAACAA CTTTTTGACC ATGTTCCCTG TAACTTATAC ATTTGAGAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |