Gene Symbol | wve-1 |
Entrez Gene ID | 187639 |
Full Name | WAVE (actin cytoskeleton modulator) homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » wve-1 cDNA ORF clone
Gene Symbol | wve-1 |
Entrez Gene ID | 187639 |
Full Name | WAVE (actin cytoskeleton modulator) homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001264832.2 | NP_001251761.1 | WH2 domain-containing protein |
NM_001264833.1 | NP_001251762.1 | WAVE (actin cytoskeleton modulator) homolog |
NM_001264832.1 | NP_001251761.1 | WAVE (actin cytoskeleton modulator) homolog |
NM_001264833.2 | NP_001251762.1 | WH2 domain-containing protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The WAVE complex is the main activator of the Arp2/3 complex for actin filament nucleation and assembly in the lamellipodia of moving cells.
Title: WAVE binds Ena/VASP for enhanced Arp2/3 complex-based actin assembly.
WAVE/SCAR promotes endocytosis and early endosome morphology in polarized C. elegans epithelia.
Title: WAVE/SCAR promotes endocytosis and early endosome morphology in polarized C. elegans epithelia.
UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph polarize F-actin during embryonic morphogenesis by regulating the WAVE/SCAR actin nucleation complex.
Title: UNC-40/DCC, SAX-3/Robo, and VAB-1/Eph polarize F-actin during embryonic morphogenesis by regulating the WAVE/SCAR actin nucleation complex.
results support a model in which the MIG-15 kinase and the UNC-116-WVE-1 complex act on opposite sides of the growth cone to promote robust directional migration
Title: MIG-15 and ERM-1 promote growth cone directional migration in parallel to UNC-116 and WVE-1.
in Caenorhabditis elegans, WH2-domain-containing activator of the Arp2/3 complex, WVE-1/WAVE acts redundantly with WSP-1/WASP in axon guidance
Title: The Arp2/3 activators WAVE and WASP have distinct genetic interactions with Rac GTPases in Caenorhabditis elegans axon guidance.
The following wve-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the wve-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335504 | |
Clone ID Related Accession (Same CDS sequence) | NM_001264832.2 , NM_001264832.1 | |
Accession Version | NM_001264832.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1407bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | WH2 domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001264832.1. |
1 | ATGCCTCTAA CAAAACGGGC GGTATCACCG GTAAACCTCA GCAGAGGCAC AATTCCATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001251761.1 |
CDS | 7..1413 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001264832.2 |
1 | ATGCCTCTAA CAAAACGGGC GGTATCACCG GTAAACCTCA GCAGAGGCAC AATTCCATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336576 | |
Clone ID Related Accession (Same CDS sequence) | NM_001264833.1 , NM_001264833.2 | |
Accession Version | NM_001264833.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | WH2 domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001264833.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGGTTGCCC CAATCGGAAT GACAATGCAC CATCATCCTC AACAAAATGT GCATCCGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001251762.1 |
CDS | 1..654 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001264833.2 |
1 | ATGGTTGCCC CAATCGGAAT GACAATGCAC CATCATCCTC AACAAAATGT GCATCCGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335504 | |
Clone ID Related Accession (Same CDS sequence) | NM_001264832.2 , NM_001264832.1 | |
Accession Version | NM_001264832.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1407bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | WAVE (actin cytoskeleton modulator) homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGCCTCTAA CAAAACGGGC GGTATCACCG GTAAACCTCA GCAGAGGCAC AATTCCATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001251761.1 |
CDS | 1..1407 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001264832.1 |
1 | ATGCCTCTAA CAAAACGGGC GGTATCACCG GTAAACCTCA GCAGAGGCAC AATTCCATCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336576 | |
Clone ID Related Accession (Same CDS sequence) | NM_001264833.1 , NM_001264833.2 | |
Accession Version | NM_001264833.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | WAVE (actin cytoskeleton modulator) homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGGTTGCCC CAATCGGAAT GACAATGCAC CATCATCCTC AACAAAATGT GCATCCGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001251762.1 |
CDS | 1..654 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001264833.1 |
1 | ATGGTTGCCC CAATCGGAAT GACAATGCAC CATCATCCTC AACAAAATGT GCATCCGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |