Gene Symbol | elt-2 |
Entrez Gene ID | 181250 |
Full Name | Transcription factor elt-2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » elt-2 cDNA ORF clone
Gene Symbol | elt-2 |
Entrez Gene ID | 181250 |
Full Name | Transcription factor elt-2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_077354.4 | NP_509755.2 | Transcription factor elt-2 |
NM_077354.5 | NP_509755.2 | Transcription factor elt-2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The authors determined that the GATA transcription factor ELT-2 and the p38 MAP kinase PMK-1 are necessary for animals to successfully recover from an acute Pseudomonas aeruginosa infection.
Title: Role of GATA transcription factor ELT-2 and p38 MAPK PMK-1 in recovery from acute P. aeruginosa infection in C. elegans.
the C. elegans 44 bp enhancer from vit-2 vitellogenin gene is directly regulated by ELT-2, MAB-3, FKH-9 and DAF-16 and indirectly regulated by the germline, by daf-2/insulin signaling and by the TGF-beta/Sma/Mab pathway
Title: A 44 bp intestine-specific hermaphrodite-specific enhancer from the C. elegans vit-2 vitellogenin gene is directly regulated by ELT-2, MAB-3, FKH-9 and DAF-16 and indirectly regulated by the germline, by daf-2/insulin signaling and by the TGF-?/Sma/Mab pathway.
Overexpression of elt-2 extends lifespan and slows the rate of gene expression changes that occur during normal aging. Thus, our results identify the developmental regulator ELT-2 as a major driver of normal aging in C. elegans
Title: Deactivation of the GATA Transcription Factor ELT-2 Is a Major Driver of Normal Aging in C. elegans.
GATA motifs played largely subtle roles in modulating postembryonic levels of elt-2
Title: Mutagenesis of GATA motifs controlling the endoderm regulator elt-2 reveals distinct dominant and secondary cis-regulatory elements.
The rpn-10 mutant animals survive through the activation of compensatory mechanisms regulated by the conserved SKN-1/Nrf2 and ELT-2/GATA transcription factors that mediate the increased expression of genes encoding proteasome subunits.
Title: Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway.
The following elt-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the elt-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa348487 | |
Clone ID Related Accession (Same CDS sequence) | NM_077354.4 , NM_077354.5 | |
Accession Version | NM_077354.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Transcription factor elt-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_077354.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGATAATA ACTACAATGA TAATGTCAAC GGCTGGGCCG AAATGGAACC ATCTCAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509755.2 |
CDS | 1..1302 |
Translation |
Target ORF information:
Target ORF information:
|
NM_077354.4 |
1 | ATGGATAATA ACTACAATGA TAATGTCAAC GGCTGGGCCG AAATGGAACC ATCTCAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa348487 | |
Clone ID Related Accession (Same CDS sequence) | NM_077354.4 , NM_077354.5 | |
Accession Version | NM_077354.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1302bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Transcription factor elt-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_077354.4. |
1 | ATGGATAATA ACTACAATGA TAATGTCAAC GGCTGGGCCG AAATGGAACC ATCTCAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509755.2 |
CDS | 2..1303 |
Translation |
Target ORF information:
Target ORF information:
|
NM_077354.5 |
1 | ATGGATAATA ACTACAATGA TAATGTCAAC GGCTGGGCCG AAATGGAACC ATCTCAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |