Gene Symbol | pak-1 |
Entrez Gene ID | 180873 |
Full Name | Serine/threonine-protein kinase pak-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pak-1 cDNA ORF clone
Gene Symbol | pak-1 |
Entrez Gene ID | 180873 |
Full Name | Serine/threonine-protein kinase pak-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001029206.2 | NP_001024377.1 | Serine/threonine-protein kinase pak-1 |
NM_001029206.3 | NP_001024377.1 | Serine/threonine-protein kinase pak-1 |
NM_001029207.2 | NP_001024378.1 | Serine/threonine-protein kinase pak-1 |
NM_001029208.3 | NP_001024379.1 | Serine/threonine-protein kinase pak-1 |
NM_001029207.3 | NP_001024378.1 | Serine/threonine-protein kinase pak-1 |
NM_001029208.4 | NP_001024379.1 | Serine/threonine-protein kinase pak-1 |
NM_001029209.5 | NP_001024380.1 | Serine/threonine-protein kinase pak-1 |
NM_001029209.3 | NP_001024380.1 | Serine/threonine-protein kinase pak-1 |
Rattus norvegicus (Norway rat) | Pak1 | NP_058894.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002986 | XP_311901.5 |
Schizosaccharomyces pombe (fission yeast) | shk1 | NP_596626.1 |
Pan troglodytes (chimpanzee) | PAK1 | XP_508657.3 |
Saccharomyces cerevisiae (baker's yeast) | STE20 | NP_011856.1 |
Homo sapiens (human) | PAK1 | NP_002567.3 |
Caenorhabditis elegans (roundworm) | pak-1 | NP_001024378.1 |
Canis lupus familiaris (dog) | PAK1 | XP_849651.1 |
Bos taurus (cattle) | PAK1 | NP_001070366.1 |
Danio rerio (zebrafish) | pak1 | NP_958485.1 |
PAK1 | XP_001090310.1 | |
Mus musculus (house mouse) | Pak1 | NP_035165.2 |
Gallus gallus (chicken) | PAK1 | NP_001155844.1 |
Drosophila melanogaster (fruit fly) | Pak | NP_001262313.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
FOXO-Pak1 pathway was recently shown to regulate mammalian neuronal polarity, our findings indicate that the roles of FOXO and Pak1 in neuronal migration are most likely conserved from C. elegans to higher organisms.
Title: Nonautonomous regulation of neuronal migration by insulin signaling, DAF-16/FOXO, and PAK-1.
PAK1 promotes reproduction, whereas it inactivates HSP16.2 gene and shortens lifespan.
Title: PAK1-deficiency/down-regulation reduces brood size, activates HSP16.2 gene and extends lifespan in Caenorhabditis elegans.
Pak-1 interacts with Wnt signaling to regulate tissue polarity and gene expression.
Title: p21-activated kinase interacts with Wnt signaling to regulate tissue polarity and gene expression.
Data show that combined loss of ROCK and PAK, or ROCK and MRCK, completely prevented embryonic elongation, but a constitutively active form of MLC-4 could only rescue a lack of MRCK.
Title: Myosin II regulation during C. elegans embryonic elongation: LET-502/ROCK, MRCK-1 and PAK-1, three kinases with different roles.
only PAK-1 functions in the GIT/PIX/PAK pathway independently of RAC/CDC42 GTPases.
Title: A RAC/CDC-42-independent GIT/PIX/PAK signaling pathway mediates cell migration in C. elegans.
The following pak-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pak-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa349257 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029209.5 , NM_001029209.3 | |
Accession Version | NM_001029209.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 375bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase pak-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_001029209.4. |
1 | ATGGTCGGAA CTCCATACTG GATGGCGCCG GAAGTGGTGA CCCGCAAACA ATACGGACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024380.1 |
CDS | 1352..1726 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029209.5 |
1 | ATGGTCGGAA CTCCATACTG GATGGCGCCG GAAGTGGTGA CCCGCAAACA ATACGGACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349257 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029209.5 , NM_001029209.3 | |
Accession Version | NM_001029209.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 375bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase pak-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_001029209.2. COMPLETENESS: incomplete on both ends. |
1 | ATGGTCGGAA CTCCATACTG GATGGCGCCG GAAGTGGTGA CCCGCAAACA ATACGGACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024380.1 |
CDS | 1..375 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029209.3 |
1 | ATGGTCGGAA CTCCATACTG GATGGCGCCG GAAGTGGTGA CCCGCAAACA ATACGGACCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349254 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029206.2 , NM_001029206.3 | |
Accession Version | NM_001029206.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase pak-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_001029206.1. COMPLETENESS: incomplete on both ends. |
1 | ATGAAAGCTT TCTCATCGTA TGATGAGAAA CCACCAGCAC CACCAATTCG TTTCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024377.1 |
CDS | 1..1719 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029206.2 |
1 | ATGAAAGCTT TCTCATCGTA TGATGAGAAA CCACCAGCAC CACCAATTCG TTTCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349254 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029206.2 , NM_001029206.3 | |
Accession Version | NM_001029206.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase pak-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_001029206.2. |
1 | ATGAAAGCTT TCTCATCGTA TGATGAGAAA CCACCAGCAC CACCAATTCG TTTCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024377.1 |
CDS | 11..1729 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029206.3 |
1 | ATGAAAGCTT TCTCATCGTA TGATGAGAAA CCACCAGCAC CACCAATTCG TTTCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349255 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029207.2 , NM_001029207.3 | |
Accession Version | NM_001029207.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase pak-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 27, 2008 this sequence version replaced NM_001029207.1. COMPLETENESS: incomplete on both ends. |
1 | ATGAAAGCTT TCTCATCGTA TGATGAGAAA CCACCAGCAC CACCAATTCG TTTCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024378.1 |
CDS | 1..1710 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029207.2 |
1 | ATGAAAGCTT TCTCATCGTA TGATGAGAAA CCACCAGCAC CACCAATTCG TTTCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349255 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029207.2 , NM_001029207.3 | |
Accession Version | NM_001029207.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase pak-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_001029207.2. |
1 | ATGAAAGCTT TCTCATCGTA TGATGAGAAA CCACCAGCAC CACCAATTCG TTTCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024378.1 |
CDS | 13..1722 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029207.3 |
1 | ATGAAAGCTT TCTCATCGTA TGATGAGAAA CCACCAGCAC CACCAATTCG TTTCAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349256 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029208.3 , NM_001029208.4 | |
Accession Version | NM_001029208.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1572bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase pak-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_001029208.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCCTAACC CGTTCATGAA AAAGAACAAA GACAAAAAGG AAGCGTCAGA AAAACCAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024379.1 |
CDS | 1..1572 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029208.3 |
1 | ATGCCTAACC CGTTCATGAA AAAGAACAAA GACAAAAAGG AAGCGTCAGA AAAACCAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa349256 | |
Clone ID Related Accession (Same CDS sequence) | NM_001029208.3 , NM_001029208.4 | |
Accession Version | NM_001029208.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1572bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Serine/threonine-protein kinase pak-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_001029208.3. |
1 | ATGCCTAACC CGTTCATGAA AAAGAACAAA GACAAAAAGG AAGCGTCAGA AAAACCAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001024379.1 |
CDS | 58..1629 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001029208.4 |
1 | ATGCCTAACC CGTTCATGAA AAAGAACAAA GACAAAAAGG AAGCGTCAGA AAAACCAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |