Gene Symbol | ced-3 |
Entrez Gene ID | 178272 |
Full Name | Cell death protein 3 subunit p17 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » ced-3 cDNA ORF clone
Gene Symbol | ced-3 |
Entrez Gene ID | 178272 |
Full Name | Cell death protein 3 subunit p17 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001268780.2 | NP_001255709.1 | Cell death protein 3 subunit p17 |
NM_001268779.1 | NP_001255708.1 | Cell death protein 3 subunit p17 |
NM_001268780.1 | NP_001255709.1 | Cell death protein 3 subunit p17 |
NM_001268779.2 | NP_001255708.1 | Cell death protein 3 subunit p17 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Utilizing high-throughput screening with recombinant C. elegans CED-3 protein, we have discovered and confirmed 21 novel small molecule inhibitors.
Title: Discovery of small molecule inhibitors for the C.?elegans caspase CED-3 by high-throughput screening.
show that CED-3 caspase and the E3 ubiquitin ligase UBR-1 form a complex that couples their in vivo activities, allowing for recognition and rapid degradation of LIN-28 and thus facilitating a switch in developmental programs
Title: Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development.
The nuclear-pore protein NPP-14 interacts with the CED-3 zymogen prodomain, colocalizes with CED-3 in vivo and inhibits CED-3 autoactivation in vitro.
Title: Regulation of CED-3 caspase localization and activation by C. elegans nuclear-membrane protein NPP-14.
A protein interaction cascade involving EGL-1, CED-9, CED-4, and CED-3 results in the activation of the key cell death protease CED-3, which is tightly controlled by multiple positive and negative regulators.
Title: Programmed Cell Death During Caenorhabditis elegans Development.
A non-apoptotic function of CED-3 caspase that regulates multiple developmental events through proteolytic inactivation, is reported.
Title: CED-3 caspase acts with miRNAs to regulate non-apoptotic gene expression dynamics for robust development in C. elegans.
The following ced-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ced-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa353863 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268780.2 , NM_001268780.1 | |
Accession Version | NM_001268780.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Cell death protein 3 subunit p17 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001268780.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGAACTTTG TCGATGCACC AACCATAAGC CGTGTTTTCG ACGAGAAAAC CATGTACAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255709.1 |
CDS | 1..864 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268780.2 |
1 | ATGAACTTTG TCGATGCACC AACCATAAGC CGTGTTTTCG ACGAGAAAAC CATGTACAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353863 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268780.2 , NM_001268780.1 | |
Accession Version | NM_001268780.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 864bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Cell death protein 3 subunit p17 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGAACTTTG TCGATGCACC AACCATAAGC CGTGTTTTCG ACGAGAAAAC CATGTACAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255709.1 |
CDS | 1..864 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268780.1 |
1 | ATGAACTTTG TCGATGCACC AACCATAAGC CGTGTTTTCG ACGAGAAAAC CATGTACAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342395 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268779.1 , NM_001268779.2 | |
Accession Version | NM_001268779.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Cell death protein 3 subunit p17 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGATGCGTC AAGATAGAAG GAGCTTGCTA GAGAGGAACA TTATGATGTT CTCTAGTCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255708.1 |
CDS | 1..1512 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268779.1 |
1 | ATGATGCGTC AAGATAGAAG GAGCTTGCTA GAGAGGAACA TTATGATGTT CTCTAGTCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342395 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268779.1 , NM_001268779.2 | |
Accession Version | NM_001268779.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1512bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Cell death protein 3 subunit p17 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001268779.1. |
1 | ATGATGCGTC AAGATAGAAG GAGCTTGCTA GAGAGGAACA TTATGATGTT CTCTAGTCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255708.1 |
CDS | 72..1583 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268779.2 |
1 | ATGATGCGTC AAGATAGAAG GAGCTTGCTA GAGAGGAACA TTATGATGTT CTCTAGTCAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |