Gene Symbol | unc-5 |
Entrez Gene ID | 177334 |
Full Name | Netrin receptor unc-5 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » unc-5 cDNA ORF clone
Gene Symbol | unc-5 |
Entrez Gene ID | 177334 |
Full Name | Netrin receptor unc-5 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001306823.1 | NP_001293752.1 | Netrin receptor unc-5 |
NM_068422.5 | NP_500823.1 | Netrin receptor unc-5 |
NM_001306820.1 | NP_001293749.1 | Netrin receptor unc-5 |
NM_001306821.1 | NP_001293750.1 | Netrin receptor unc-5 |
NM_068421.4 | NP_500822.2 | Netrin receptor unc-5 |
NM_068422.6 | NP_500823.1 | Netrin receptor unc-5 |
NM_001306822.1 | NP_001293751.1 | Netrin receptor unc-5 |
NM_001372820.1 | NP_001360311.1 | Netrin receptor unc-5 |
NM_068421.5 | NP_500822.2 | Netrin receptor unc-5 |
NM_001306820.2 | NP_001293749.1 | Netrin receptor unc-5 |
NM_001306821.2 | NP_001293750.1 | Netrin receptor unc-5 |
NM_001306822.2 | NP_001293751.1 | Netrin receptor unc-5 |
Homo sapiens (human) | UNC5B | NP_734465.2 |
UNC5B | XP_001106162.2 | |
Gallus gallus (chicken) | UNC5B | NP_001026396.2 |
Caenorhabditis elegans (roundworm) | unc-5 | NP_500823.1 |
Pan troglodytes (chimpanzee) | UNC5B | XP_001135844.2 |
Mus musculus (house mouse) | Unc5b | NP_084046.2 |
Rattus norvegicus (Norway rat) | Unc5b | NP_071543.1 |
Danio rerio (zebrafish) | unc5b | NP_001104619.1 |
Xenopus tropicalis (tropical clawed frog) | unc5b | XP_004916000.1 |
Canis lupus familiaris (dog) | UNC5B | XP_850428.1 |
Bos taurus (cattle) | UNC5B | NP_001092499.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Small GTPases mediate MOM-5's regulation of unc-5 such that one outcome of impaired function of small GTPases like CED-10/Rac and MIG-2/RhoG is an increase in unc-5 function.
Title: The Wnt Frizzled Receptor MOM-5 Regulates the UNC-5 Netrin Receptor through Small GTPase-Dependent Signaling to Determine the Polarity of Migrating Cells.
The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP.
Title: The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP.
UNC-6/netrin, UNC-5 and UNC-40/DCC modulated the extent of growth cone protrusion. Loss-of-function unc-5 mutants displayed increased protrusion in repelled growth cones, whereas loss-of-function unc-6 or unc-40 mutants caused decreased protrusion.
Title: UNC-6/netrin and its receptors UNC-5 and UNC-40/DCC modulate growth cone protrusion in vivo in C. elegans.
The enhancement of unc-5 caused by an sdn-1 mutation was rescued by expression of wild-type sdn-1 in the hypodermis or nervous system rather than the distal tip cell (DTC)
Title: SDN-1/syndecan regulates growth factor signaling in distal tip cell migrations in C. elegans.
UNC-129, graded opposite to UNC-6/netrin, functions independent of the canonical TGF-beta receptors to regulate UNC-5 cellular responses
Title: UNC-129 regulates the balance between UNC-40 dependent and independent UNC-5 signaling pathways.
The following unc-5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the unc-5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa343300 | |
Clone ID Related Accession (Same CDS sequence) | NM_068422.5 , NM_068422.6 | |
Accession Version | NM_068422.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2760bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_068422.4. COMPLETENESS: incomplete on both ends. |
1 | ATGGACGAAA TCACAATCAC AACACAACCA AAATCCGGTT ATGTCATTCG AAATAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_500823.1 |
CDS | 1..2760 |
Translation |
Target ORF information:
Target ORF information:
|
NM_068422.5 |
1 | ATGGACGAAA TCACAATCAC AACACAACCA AAATCCGGTT ATGTCATTCG AAATAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343300 | |
Clone ID Related Accession (Same CDS sequence) | NM_068422.5 , NM_068422.6 | |
Accession Version | NM_068422.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2760bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_068422.5. |
1 | ATGGACGAAA TCACAATCAC AACACAACCA AAATCCGGTT ATGTCATTCG AAATAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_500823.1 |
CDS | 3..2762 |
Translation |
Target ORF information:
Target ORF information:
|
NM_068422.6 |
1 | ATGGACGAAA TCACAATCAC AACACAACCA AAATCCGGTT ATGTCATTCG AAATAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343301 | |
Clone ID Related Accession (Same CDS sequence) | NM_068421.4 , NM_068421.5 | |
Accession Version | NM_068421.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_068421.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGACGAAA TCACAATCAC AACACAACCA AAATCCGGTT ATGTCATTCG AAATAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_500822.2 |
CDS | 1..1704 |
Translation |
Target ORF information:
Target ORF information:
|
NM_068421.4 |
1 | ATGGACGAAA TCACAATCAC AACACAACCA AAATCCGGTT ATGTCATTCG AAATAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343301 | |
Clone ID Related Accession (Same CDS sequence) | NM_068421.4 , NM_068421.5 | |
Accession Version | NM_068421.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_068421.4. |
1 | ATGGACGAAA TCACAATCAC AACACAACCA AAATCCGGTT ATGTCATTCG AAATAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_500822.2 |
CDS | 3..1706 |
Translation |
Target ORF information:
Target ORF information:
|
NM_068421.5 |
1 | ATGGACGAAA TCACAATCAC AACACAACCA AAATCCGGTT ATGTCATTCG AAATAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353237 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306820.1 , NM_001306820.2 | |
Accession Version | NM_001306820.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2844bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGGAGGACG ACACGCCCGA TGTGAGTTCA GATTCCAATG GAGATGCAGC ATACAGCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293749.1 |
CDS | 1..2844 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306820.1 |
1 | ATGGAGGACG ACACGCCCGA TGTGAGTTCA GATTCCAATG GAGATGCAGC ATACAGCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353237 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306820.1 , NM_001306820.2 | |
Accession Version | NM_001306820.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2844bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001306820.1. |
1 | ATGGAGGACG ACACGCCCGA TGTGAGTTCA GATTCCAATG GAGATGCAGC ATACAGCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293749.1 |
CDS | 3..2846 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306820.2 |
1 | ATGGAGGACG ACACGCCCGA TGTGAGTTCA GATTCCAATG GAGATGCAGC ATACAGCGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353238 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306821.1 , NM_001306821.2 | |
Accession Version | NM_001306821.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGCGGAAGC ACTTTCTCAA ATCACCCGTT GCTCAACGGG TTCAAGAAGG CACAACCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293750.1 |
CDS | 1..2436 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306821.1 |
1 | ATGCGGAAGC ACTTTCTCAA ATCACCCGTT GCTCAACGGG TTCAAGAAGG CACAACCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353238 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306821.1 , NM_001306821.2 | |
Accession Version | NM_001306821.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2436bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001306821.1. |
1 | ATGCGGAAGC ACTTTCTCAA ATCACCCGTT GCTCAACGGG TTCAAGAAGG CACAACCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293750.1 |
CDS | 5..2440 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306821.2 |
1 | ATGCGGAAGC ACTTTCTCAA ATCACCCGTT GCTCAACGGG TTCAAGAAGG CACAACCCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353239 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306822.1 , NM_001306822.2 | |
Accession Version | NM_001306822.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2259bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGTCAGCCG CCAGATTATC AGACAGTGGA AATTATACAT GTGAAGCCAC AAATGTGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293751.1 |
CDS | 1..2259 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306822.1 |
1 | ATGTCAGCCG CCAGATTATC AGACAGTGGA AATTATACAT GTGAAGCCAC AAATGTGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353239 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306822.1 , NM_001306822.2 | |
Accession Version | NM_001306822.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2259bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001306822.1. |
1 | ATGTCAGCCG CCAGATTATC AGACAGTGGA AATTATACAT GTGAAGCCAC AAATGTGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293751.1 |
CDS | 27..2285 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306822.2 |
1 | ATGTCAGCCG CCAGATTATC AGACAGTGGA AATTATACAT GTGAAGCCAC AAATGTGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353240 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306823.1 , NM_001372820.1 | |
Accession Version | NM_001306823.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGACGAGAA GCTGTAAAGT ACCATGTAAA CTTGATGGAG GATGGAGTTC ATGGAGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293752.1 |
CDS | 1..1974 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306823.1 |
1 | ATGACGAGAA GCTGTAAAGT ACCATGTAAA CTTGATGGAG GATGGAGTTC ATGGAGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa353240 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306823.1 , NM_001372820.1 | |
Accession Version | NM_001372820.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1974bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Netrin receptor unc-5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). |
1 | ATGACGAGAA GCTGTAAAGT ACCATGTAAA CTTGATGGAG GATGGAGTTC ATGGAGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001360311.1 |
CDS | 502..2475 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001372820.1 |
1 | ATGACGAGAA GCTGTAAAGT ACCATGTAAA CTTGATGGAG GATGGAGTTC ATGGAGTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |