Unc5b cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Unc5b
Entrez Gene ID	107449
Full Name	unc-5 netrin receptor B
Synonyms	6330415E02Rik,A630020F16,D10Bwg0792e,Unc5h2
General protein information	Preferred Names unc-5 netrin receptor B Names netrin receptor UNC5B protein unc-5 homolog 2 protein unc-5 homolog B unc5 homolog 2
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 10 Map Location: 10 B4\|10 31.52 cM

mRNA and Protein(s)

mRNA	Protein	Name
XM_006513028.3	XP_006513091.1	netrin receptor UNC5B isoform X1
NM_029770.2	NP_084046.2	netrin receptor UNC5B precursor
NM_029770.3	NP_084046.2	netrin receptor UNC5B isoform 1 precursor
NM_001359273.1	NP_001346202.1	netrin receptor UNC5B isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	UNC5B	NP_734465.2
	UNC5B	XP_001106162.2
Gallus gallus (chicken)	UNC5B	NP_001026396.2
Caenorhabditis elegans (roundworm)	unc-5	NP_500823.1
Pan troglodytes (chimpanzee)	UNC5B	XP_001135844.2
Mus musculus (house mouse)	Unc5b	NP_084046.2
Rattus norvegicus (Norway rat)	Unc5b	NP_071543.1
Danio rerio (zebrafish)	unc5b	NP_001104619.1
Xenopus tropicalis (tropical clawed frog)	unc5b	XP_004916000.1
Canis lupus familiaris (dog)	UNC5B	XP_850428.1
Bos taurus (cattle)	UNC5B	NP_001092499.1

Gene Ontology
Bibliography

Related articles in PubMed

Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling.
Tai-Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, Ieda M, Takakura N, Nakagawa O, Zhou B, Okabayashi K, Suematsu M, Kitagawa Y, Bastmeyer M, Sato K, Klein R, Navankasattusas S, Li DY, Yamagishi S, Kubota Y
Development (Cambridge, England)144(13)2392-2401(2017 07)

Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-?-Acetyltransferase 10 (Naa10).
Xu H, Han Y, Liu B, Li R
Scientific reports638508(2016 Dec)

Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis.
Mediero A, Wilder T, Ramkhelawon B, Moore KJ, Cronstein BN
FASEB journal : official publication of the Federation of American Societies for Experimental Biology30(11)3835-3844(2016 11)

Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.
Grandin M, Meier M, Delcros JG, Nikodemus D, Reuten R, Patel TR, Goldschneider D, Orriss G, Krahn N, Boussouar A, Abes R, Dean Y, Neves D, Bernet A, Depil S, Schneiders F, Poole K, Dante R, Koch M, Mehlen P, Stetefeld J
Cancer cell29(2)173-85(2016 Feb)

Widespread Differential Expression of Coding Region and 3' UTR Sequences in Neurons and Other Tissues.
Kocabas A, Duarte T, Kumar S, Hynes MA
Neuron88(6)1149-56(2015 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

fibronectin leucine-rich transmembrane protein 2 (FLRT2), a repulsive ligand of the UNC5 receptor family for neurons, is unexpectedly expressed in endothelial cells specifically in the placental labyrinth.
Title: Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling.

Blockade of Netrin-1/Unc5b by monoclonal antibodies prevents bone destruction and reduces the severity of K/BxN serum transfer-induced arthritis
Title: Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis.

Data showed that albuminuria was significantly more pronounced in mice with proximal tubule specific deletion of UNC5B.
Title: Deletion of UNC5B in Kidney Epithelium Exacerbates Diabetic Nephropathy in Mice.

UNC5B receptor deletion exacerbates DSS-induced colitis in mice by increasing epithelial cell apoptosis.
Title: UNC5B receptor deletion exacerbates DSS-induced colitis in mice by increasing epithelial cell apoptosis.

unc5b expression is greater in adipose tissue of obese versus lean mice.
Title: Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.

The following Unc5b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Unc5b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OMu44068	NM_001359273.1 Latest version!	Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu44068	XM_006513028.3 Latest version!	Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OMu18210	NM_029770.3 Latest version!	Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$559.30 $799.00
View Old Accession Versions >>
OMu18210	NM_029770.2	Mus musculus unc-5 netrin receptor B (Unc5b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$559.30 $799.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Unc5b ( NM_001359273.1 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001346202.1 Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OMu44068
Clone ID Related Accession (Same CDS sequence)	XM_006513028.3 , NM_001359273.1
Accession Version	NM_001359273.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Mus musculus(house mouse)
Product	netrin receptor UNC5B isoform 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK018177.1, BC048162.1, AK147603.1 and AW488068.1. On Dec 30, 2017 this sequence version replaced XM_006513028.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC048162.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGGCCC GGAGCGGGGT GCGGAGCGCG CTGCTGCTGG CGCTGCTGCT TTGCTGGGAT 
CCGACACCGA GCCTAGCAGG CGTTGACTCT GCTGGCCAGG TGCTCCCAGA CTCCTACCCA 
TCAGCCCCTG CGGAGCAGCT GCCGTACTTC CTATTGGAGC CACAGGACGC CTACATCGTA 
AAGAACAAGC CAGTGGAACT GCACTGCAGA GCCTTCCCTG CCACGCAGAT CTACTTCAAG 
TGTAATGGCG AGTGGGTCAG CCAGAATGAC CACGTCACAC AGGAGAGCCT GGATGAGGCC 
ACAGGCTTGC GGGTGCGAGA GGTGCAGATC GAGGTGTCAC GGCAGCAAGT GGAGGAACTC 
TTCGGGCTCG AGGACTACTG GTGCCAGTGC GTGGCCTGGA GCTCTTCGGG AACTACCAAG 
AGTCGCCGAG CCTACATCCG CATTGCCTAC TTGCGCAAGA ACTTTGACCA GGAGCCTCTG 
GCCAAGGAGG TACCCTTGGA TCATGAGGTC CTTCTGCAGT GCCGCCCACC GGAGGGAGTG 
CCTGTGGCTG AGGTGGAATG GCTCAAGAAT GAAGATGTCA TTGACCCCGC TCAGGACACT 
AACTTCCTGC TCACCATTGA CCACAACCTC ATCATCCGCC AGGCGCGCCT CTCAGACACG 
GCCAACTACA CCTGTGTGGC CAAGAATATC GTGGCCAAGC GCCGGAGCAC CACGGCCACA 
GTCATCGTCT ATGTGAATGG AGGCTGGTCC AGCTGGGCAG AGTGGTCACC CTGTTCCAAT 
CGCTGTGGCC GAGGCTGGCA GAAGCGTACT CGGACCTGCA CCAATCCAGC CCCACTCAAT 
GGAGGCGCCT TCTGTGAGGG ACAGGCCTTC CAGAAGACAG CTTGCACCAC CGTGTGCCCA 
GTGGATGGAG CGTGGACCGA GTGGAGCAAG TGGTCTGCCT GCAGCACAGA GTGTGCGCAC 
TGGCGCAGCC GCGAGTGCAT GGCACCGCCA CCCCAGAACG GAGGCCGTGA CTGCAGCGGG 
ACGCTACTTG ACTCCAAGAA CTGCACTGAT GGGCTGTGCG TGCTGACCCT GGAGACATCG 
GGAGATGTGG CACTGTACGC AGGCCTTGTG GTGGCCGTCT TTGTGGTGGT AGCGGTTCTC 
ATGGCCGTGG GAGTGATCGT ATACCGGAGA AACTGCCGGG ACTTCGACAC GGACATCACC 
GACTCCTCTG CGGCCCTCAC TGGTGGCTTC CACCCTGTCA ACTTCAAGAC TGCAAGGCCC 
AACAACCCGC AGCTCCTGCA CCCGTCCGCC CCTCCAGACC TAACGGCCAG TGCTGGCATC 
TACCGCGGGC CTGTGTATGC CCTGCAGGAC TCCGCCGACA AGATCCCCAT GACTAATTCG 
CCCCTGCTGG ATCCCCTGCC CAGCCTCAAG ATCAAGGTCT ATAACTCCAG CACCATCGGT 
TCTGGGTCTG GCCTGGCTGA TGGAGCCGAC CTGCTGGGTG TCCTCCCGCC GGGCACGTAC 
CCAGGCGATT TCTCCCGGGA CACCCATTTC CTGCACCTGC GCAGTGCCAG CCTTGGTTCC 
CAGCACCTCC TGGGCCTACC TCGGGACCCC AGCAGCAGTG TCAGCGGCAC CTTTGGTTGC 
CTGGGAGGAA GGCTGAGCCT CCCCGGCACA GGGGTCAGCC TGTTGGTACC AAATGGAGCC 
ATTCCCCAGG GCAAGTTCTA TGACCTGTAT CTACATATCA ACAAGGCCGA AAGCACCCTC 
CCACTTTCAG AAGGTTCCCA GACAGTATTG AGCCCCTCGG TGACCTGTGG GCCCACAGGC 
CTACTCCTGT GCCGCCCTGT CGTCCTCACC GTGCCCCACT GTGCTGAAGT CATCGCTGGA 
GACTGGATCT TTCAGCTCAA GACCCAGGCC CATCAGGGCC ACTGGGAGGA GGTGGTGACC 
TTGGATGAGG AGACCCTCAA CACACCCTGC TACTGCCAGC TGGAGGCTAA GTCCTGCCAC 
ATCCTGCTGG ACCAGCTGGG TACCTACGTA TTCATGGGCG AGTCCTACTC TCGCTCTGCA 
GTCAAGCGGC TCCAGCTGGC CATCTTCGCC CCAGCCCTCT GCACCTCCCT GGAGTATAGC 
CTCAGGGTCT ACTGTCTGGA GGACACACCT GTAGCACTGA AGGAGGTCCT GGAGCTGGAG 
AGGACTCTGG GTGGCTACTT GGTGGAGGAG CCCAAGCCTT TGCTCTTTAA GGACAGTTAC 
CACAACCTAC GCCTCTCCCT CCATGACATC CCCCATGCCC ACTGGAGGAG CAAACTACTG 
GCCAAGTACC AGGAGATTCC CTTCTACCAC GTCTGGAATG GCAGCCAGAG AGCCCTGCAC 
TGCACTTTCA CCCTGGAGAG GCATAGCCTG GCCTCCACGG AGTTCACCTG TAAGGTCTGC 
GTGCGGCAGG TCGAAGGGGA AGGCCAGATT TTCCAGCTGC ACACAACGTT GGCCGAGACG 
CCTGCTGGCT CCCTGGATGC TCTCTGCTCT GCCCCGGGCA ATGCCATCAC CACCCAGCTG 
GGACCCTATG CCTTCAAGAT ACCCCTGTCC ATCCGCCAAA AGATCTGCAG CAGCCTGGAC 
GCCCCCAACT CCCGGGGCAA CGACTGGAGG CTGTTGGCGC AGAAGCTGTC CATGGACCGG 
TACCTAAACT ACTTCGCCAC CAAAGCTAGT CCCACAGGTG TCATCTTAGA CCTCTGGGAA 
GCTCGGCAAC AGGATGACGG GGACCTCAAC AGCCTGGCCA GTGCCTTGGA GGAGATGGGC 
AAGAGTGAGA TGCTGGTAGC CATGGCCACA GATGGCGATT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001346202.1
CDS	417..3221
Translation	MRARSGVRSALLLALLLCWDPTPSLAGVDSAGQVLPDSYPSAPAEQLPYFLLEPQDAYIVKNKPVELHCRAFPATQIYFKCNGEWVSQNDHVTQESLDEATGLRVREVQIEVSRQQVEELFGLEDYWCQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLTLETSGDVALYAGLVVAVFVVVAVLMAVGVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPNNPQLLHPSAPPDLTASAGIYRGPVYALQDSADKIPMTNSPLLDPLPSLKIKVYNSSTIGSGSGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFMGESYSRSAVKRLQLAIFAPALCTSLEYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQRALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETPAGSLDALCSAPGNAITTQLGPYAFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATDGDC

Target ORF information:

RefSeq Version	NM_001359273.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001359273.1

ORF Insert Sequence:

ATGAGGGCCC GGAGCGGGGT GCGGAGCGCG CTGCTGCTGG CGCTGCTGCT TTGCTGGGAT 
CCGACACCGA GCCTAGCAGG CGTTGACTCT GCTGGCCAGG TGCTCCCAGA CTCCTACCCA 
TCAGCCCCTG CGGAGCAGCT GCCGTACTTC CTATTGGAGC CACAGGACGC CTACATCGTA 
AAGAACAAGC CAGTGGAACT GCACTGCAGA GCCTTCCCTG CCACGCAGAT CTACTTCAAG 
TGTAATGGCG AGTGGGTCAG CCAGAATGAC CACGTCACAC AGGAGAGCCT GGATGAGGCC 
ACAGGCTTGC GGGTGCGAGA GGTGCAGATC GAGGTGTCAC GGCAGCAAGT GGAGGAACTC 
TTCGGGCTCG AGGACTACTG GTGCCAGTGC GTGGCCTGGA GCTCTTCGGG AACTACCAAG 
AGTCGCCGAG CCTACATCCG CATTGCCTAC TTGCGCAAGA ACTTTGACCA GGAGCCTCTG 
GCCAAGGAGG TACCCTTGGA TCATGAGGTC CTTCTGCAGT GCCGCCCACC GGAGGGAGTG 
CCTGTGGCTG AGGTGGAATG GCTCAAGAAT GAAGATGTCA TTGACCCCGC TCAGGACACT 
AACTTCCTGC TCACCATTGA CCACAACCTC ATCATCCGCC AGGCGCGCCT CTCAGACACG 
GCCAACTACA CCTGTGTGGC CAAGAATATC GTGGCCAAGC GCCGGAGCAC CACGGCCACA 
GTCATCGTCT ATGTGAATGG AGGCTGGTCC AGCTGGGCAG AGTGGTCACC CTGTTCCAAT 
CGCTGTGGCC GAGGCTGGCA GAAGCGTACT CGGACCTGCA CCAATCCAGC CCCACTCAAT 
GGAGGCGCCT TCTGTGAGGG ACAGGCCTTC CAGAAGACAG CTTGCACCAC CGTGTGCCCA 
GTGGATGGAG CGTGGACCGA GTGGAGCAAG TGGTCTGCCT GCAGCACAGA GTGTGCGCAC 
TGGCGCAGCC GCGAGTGCAT GGCACCGCCA CCCCAGAACG GAGGCCGTGA CTGCAGCGGG 
ACGCTACTTG ACTCCAAGAA CTGCACTGAT GGGCTGTGCG TGCTGACCCT GGAGACATCG 
GGAGATGTGG CACTGTACGC AGGCCTTGTG GTGGCCGTCT TTGTGGTGGT AGCGGTTCTC 
ATGGCCGTGG GAGTGATCGT ATACCGGAGA AACTGCCGGG ACTTCGACAC GGACATCACC 
GACTCCTCTG CGGCCCTCAC TGGTGGCTTC CACCCTGTCA ACTTCAAGAC TGCAAGGCCC 
AACAACCCGC AGCTCCTGCA CCCGTCCGCC CCTCCAGACC TAACGGCCAG TGCTGGCATC 
TACCGCGGGC CTGTGTATGC CCTGCAGGAC TCCGCCGACA AGATCCCCAT GACTAATTCG 
CCCCTGCTGG ATCCCCTGCC CAGCCTCAAG ATCAAGGTCT ATAACTCCAG CACCATCGGT 
TCTGGGTCTG GCCTGGCTGA TGGAGCCGAC CTGCTGGGTG TCCTCCCGCC GGGCACGTAC 
CCAGGCGATT TCTCCCGGGA CACCCATTTC CTGCACCTGC GCAGTGCCAG CCTTGGTTCC 
CAGCACCTCC TGGGCCTACC TCGGGACCCC AGCAGCAGTG TCAGCGGCAC CTTTGGTTGC 
CTGGGAGGAA GGCTGAGCCT CCCCGGCACA GGGGTCAGCC TGTTGGTACC AAATGGAGCC 
ATTCCCCAGG GCAAGTTCTA TGACCTGTAT CTACATATCA ACAAGGCCGA AAGCACCCTC 
CCACTTTCAG AAGGTTCCCA GACAGTATTG AGCCCCTCGG TGACCTGTGG GCCCACAGGC 
CTACTCCTGT GCCGCCCTGT CGTCCTCACC GTGCCCCACT GTGCTGAAGT CATCGCTGGA 
GACTGGATCT TTCAGCTCAA GACCCAGGCC CATCAGGGCC ACTGGGAGGA GGTGGTGACC 
TTGGATGAGG AGACCCTCAA CACACCCTGC TACTGCCAGC TGGAGGCTAA GTCCTGCCAC 
ATCCTGCTGG ACCAGCTGGG TACCTACGTA TTCATGGGCG AGTCCTACTC TCGCTCTGCA 
GTCAAGCGGC TCCAGCTGGC CATCTTCGCC CCAGCCCTCT GCACCTCCCT GGAGTATAGC 
CTCAGGGTCT ACTGTCTGGA GGACACACCT GTAGCACTGA AGGAGGTCCT GGAGCTGGAG 
AGGACTCTGG GTGGCTACTT GGTGGAGGAG CCCAAGCCTT TGCTCTTTAA GGACAGTTAC 
CACAACCTAC GCCTCTCCCT CCATGACATC CCCCATGCCC ACTGGAGGAG CAAACTACTG 
GCCAAGTACC AGGAGATTCC CTTCTACCAC GTCTGGAATG GCAGCCAGAG AGCCCTGCAC 
TGCACTTTCA CCCTGGAGAG GCATAGCCTG GCCTCCACGG AGTTCACCTG TAAGGTCTGC 
GTGCGGCAGG TCGAAGGGGA AGGCCAGATT TTCCAGCTGC ACACAACGTT GGCCGAGACG 
CCTGCTGGCT CCCTGGATGC TCTCTGCTCT GCCCCGGGCA ATGCCATCAC CACCCAGCTG 
GGACCCTATG CCTTCAAGAT ACCCCTGTCC ATCCGCCAAA AGATCTGCAG CAGCCTGGAC 
GCCCCCAACT CCCGGGGCAA CGACTGGAGG CTGTTGGCGC AGAAGCTGTC CATGGACCGG 
TACCTAAACT ACTTCGCCAC CAAAGCTAGT CCCACAGGTG TCATCTTAGA CCTCTGGGAA 
GCTCGGCAAC AGGATGACGG GGACCTCAAC AGCCTGGCCA GTGCCTTGGA GGAGATGGGC 
AAGAGTGAGA TGCTGGTAGC CATGGCCACA GATGGCGATT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Unc5b ( XM_006513028.3 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_006513091.1 Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OMu44068
Clone ID Related Accession (Same CDS sequence)	XM_006513028.3 , NM_001359273.1
Accession Version	XM_006513028.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-21
Organism	Mus musculus(House mouse)
Product	netrin receptor UNC5B isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006513028.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGGCCC GGAGCGGGGT GCGGAGCGCG CTGCTGCTGG CGCTGCTGCT TTGCTGGGAT 
CCGACACCGA GCCTAGCAGG CGTTGACTCT GCTGGCCAGG TGCTCCCAGA CTCCTACCCA 
TCAGCCCCTG CGGAGCAGCT GCCGTACTTC CTATTGGAGC CACAGGACGC CTACATCGTA 
AAGAACAAGC CAGTGGAACT GCACTGCAGA GCCTTCCCTG CCACGCAGAT CTACTTCAAG 
TGTAATGGCG AGTGGGTCAG CCAGAATGAC CACGTCACAC AGGAGAGCCT GGATGAGGCC 
ACAGGCTTGC GGGTGCGAGA GGTGCAGATC GAGGTGTCAC GGCAGCAAGT GGAGGAACTC 
TTCGGGCTCG AGGACTACTG GTGCCAGTGC GTGGCCTGGA GCTCTTCGGG AACTACCAAG 
AGTCGCCGAG CCTACATCCG CATTGCCTAC TTGCGCAAGA ACTTTGACCA GGAGCCTCTG 
GCCAAGGAGG TACCCTTGGA TCATGAGGTC CTTCTGCAGT GCCGCCCACC GGAGGGAGTG 
CCTGTGGCTG AGGTGGAATG GCTCAAGAAT GAAGATGTCA TTGACCCCGC TCAGGACACT 
AACTTCCTGC TCACCATTGA CCACAACCTC ATCATCCGCC AGGCGCGCCT CTCAGACACG 
GCCAACTACA CCTGTGTGGC CAAGAATATC GTGGCCAAGC GCCGGAGCAC CACGGCCACA 
GTCATCGTCT ATGTGAATGG AGGCTGGTCC AGCTGGGCAG AGTGGTCACC CTGTTCCAAT 
CGCTGTGGCC GAGGCTGGCA GAAGCGTACT CGGACCTGCA CCAATCCAGC CCCACTCAAT 
GGAGGCGCCT TCTGTGAGGG ACAGGCCTTC CAGAAGACAG CTTGCACCAC CGTGTGCCCA 
GTGGATGGAG CGTGGACCGA GTGGAGCAAG TGGTCTGCCT GCAGCACAGA GTGTGCGCAC 
TGGCGCAGCC GCGAGTGCAT GGCACCGCCA CCCCAGAACG GAGGCCGTGA CTGCAGCGGG 
ACGCTACTTG ACTCCAAGAA CTGCACTGAT GGGCTGTGCG TGCTGACCCT GGAGACATCG 
GGAGATGTGG CACTGTACGC AGGCCTTGTG GTGGCCGTCT TTGTGGTGGT AGCGGTTCTC 
ATGGCCGTGG GAGTGATCGT ATACCGGAGA AACTGCCGGG ACTTCGACAC GGACATCACC 
GACTCCTCTG CGGCCCTCAC TGGTGGCTTC CACCCTGTCA ACTTCAAGAC TGCAAGGCCC 
AACAACCCGC AGCTCCTGCA CCCGTCCGCC CCTCCAGACC TAACGGCCAG TGCTGGCATC 
TACCGCGGGC CTGTGTATGC CCTGCAGGAC TCCGCCGACA AGATCCCCAT GACTAATTCG 
CCCCTGCTGG ATCCCCTGCC CAGCCTCAAG ATCAAGGTCT ATAACTCCAG CACCATCGGT 
TCTGGGTCTG GCCTGGCTGA TGGAGCCGAC CTGCTGGGTG TCCTCCCGCC GGGCACGTAC 
CCAGGCGATT TCTCCCGGGA CACCCATTTC CTGCACCTGC GCAGTGCCAG CCTTGGTTCC 
CAGCACCTCC TGGGCCTACC TCGGGACCCC AGCAGCAGTG TCAGCGGCAC CTTTGGTTGC 
CTGGGAGGAA GGCTGAGCCT CCCCGGCACA GGGGTCAGCC TGTTGGTACC AAATGGAGCC 
ATTCCCCAGG GCAAGTTCTA TGACCTGTAT CTACATATCA ACAAGGCCGA AAGCACCCTC 
CCACTTTCAG AAGGTTCCCA GACAGTATTG AGCCCCTCGG TGACCTGTGG GCCCACAGGC 
CTACTCCTGT GCCGCCCTGT CGTCCTCACC GTGCCCCACT GTGCTGAAGT CATCGCTGGA 
GACTGGATCT TTCAGCTCAA GACCCAGGCC CATCAGGGCC ACTGGGAGGA GGTGGTGACC 
TTGGATGAGG AGACCCTCAA CACACCCTGC TACTGCCAGC TGGAGGCTAA GTCCTGCCAC 
ATCCTGCTGG ACCAGCTGGG TACCTACGTA TTCATGGGCG AGTCCTACTC TCGCTCTGCA 
GTCAAGCGGC TCCAGCTGGC CATCTTCGCC CCAGCCCTCT GCACCTCCCT GGAGTATAGC 
CTCAGGGTCT ACTGTCTGGA GGACACACCT GTAGCACTGA AGGAGGTCCT GGAGCTGGAG 
AGGACTCTGG GTGGCTACTT GGTGGAGGAG CCCAAGCCTT TGCTCTTTAA GGACAGTTAC 
CACAACCTAC GCCTCTCCCT CCATGACATC CCCCATGCCC ACTGGAGGAG CAAACTACTG 
GCCAAGTACC AGGAGATTCC CTTCTACCAC GTCTGGAATG GCAGCCAGAG AGCCCTGCAC 
TGCACTTTCA CCCTGGAGAG GCATAGCCTG GCCTCCACGG AGTTCACCTG TAAGGTCTGC 
GTGCGGCAGG TCGAAGGGGA AGGCCAGATT TTCCAGCTGC ACACAACGTT GGCCGAGACG 
CCTGCTGGCT CCCTGGATGC TCTCTGCTCT GCCCCGGGCA ATGCCATCAC CACCCAGCTG 
GGACCCTATG CCTTCAAGAT ACCCCTGTCC ATCCGCCAAA AGATCTGCAG CAGCCTGGAC 
GCCCCCAACT CCCGGGGCAA CGACTGGAGG CTGTTGGCGC AGAAGCTGTC CATGGACCGG 
TACCTAAACT ACTTCGCCAC CAAAGCTAGT CCCACAGGTG TCATCTTAGA CCTCTGGGAA 
GCTCGGCAAC AGGATGACGG GGACCTCAAC AGCCTGGCCA GTGCCTTGGA GGAGATGGGC 
AAGAGTGAGA TGCTGGTAGC CATGGCCACA GATGGCGATT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006513091.1
CDS	434..3238
Translation	MRARSGVRSALLLALLLCWDPTPSLAGVDSAGQVLPDSYPSAPAEQLPYFLLEPQDAYIVKNKPVELHCRAFPATQIYFKCNGEWVSQNDHVTQESLDEATGLRVREVQIEVSRQQVEELFGLEDYWCQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLTLETSGDVALYAGLVVAVFVVVAVLMAVGVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPNNPQLLHPSAPPDLTASAGIYRGPVYALQDSADKIPMTNSPLLDPLPSLKIKVYNSSTIGSGSGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFMGESYSRSAVKRLQLAIFAPALCTSLEYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQRALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETPAGSLDALCSAPGNAITTQLGPYAFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATDGDC

Target ORF information:

RefSeq Version	XM_006513028.3
Organism	Mus musculus(House mouse)
Definition	Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006513028.3

ORF Insert Sequence:

ATGAGGGCCC GGAGCGGGGT GCGGAGCGCG CTGCTGCTGG CGCTGCTGCT TTGCTGGGAT 
CCGACACCGA GCCTAGCAGG CGTTGACTCT GCTGGCCAGG TGCTCCCAGA CTCCTACCCA 
TCAGCCCCTG CGGAGCAGCT GCCGTACTTC CTATTGGAGC CACAGGACGC CTACATCGTA 
AAGAACAAGC CAGTGGAACT GCACTGCAGA GCCTTCCCTG CCACGCAGAT CTACTTCAAG 
TGTAATGGCG AGTGGGTCAG CCAGAATGAC CACGTCACAC AGGAGAGCCT GGATGAGGCC 
ACAGGCTTGC GGGTGCGAGA GGTGCAGATC GAGGTGTCAC GGCAGCAAGT GGAGGAACTC 
TTCGGGCTCG AGGACTACTG GTGCCAGTGC GTGGCCTGGA GCTCTTCGGG AACTACCAAG 
AGTCGCCGAG CCTACATCCG CATTGCCTAC TTGCGCAAGA ACTTTGACCA GGAGCCTCTG 
GCCAAGGAGG TACCCTTGGA TCATGAGGTC CTTCTGCAGT GCCGCCCACC GGAGGGAGTG 
CCTGTGGCTG AGGTGGAATG GCTCAAGAAT GAAGATGTCA TTGACCCCGC TCAGGACACT 
AACTTCCTGC TCACCATTGA CCACAACCTC ATCATCCGCC AGGCGCGCCT CTCAGACACG 
GCCAACTACA CCTGTGTGGC CAAGAATATC GTGGCCAAGC GCCGGAGCAC CACGGCCACA 
GTCATCGTCT ATGTGAATGG AGGCTGGTCC AGCTGGGCAG AGTGGTCACC CTGTTCCAAT 
CGCTGTGGCC GAGGCTGGCA GAAGCGTACT CGGACCTGCA CCAATCCAGC CCCACTCAAT 
GGAGGCGCCT TCTGTGAGGG ACAGGCCTTC CAGAAGACAG CTTGCACCAC CGTGTGCCCA 
GTGGATGGAG CGTGGACCGA GTGGAGCAAG TGGTCTGCCT GCAGCACAGA GTGTGCGCAC 
TGGCGCAGCC GCGAGTGCAT GGCACCGCCA CCCCAGAACG GAGGCCGTGA CTGCAGCGGG 
ACGCTACTTG ACTCCAAGAA CTGCACTGAT GGGCTGTGCG TGCTGACCCT GGAGACATCG 
GGAGATGTGG CACTGTACGC AGGCCTTGTG GTGGCCGTCT TTGTGGTGGT AGCGGTTCTC 
ATGGCCGTGG GAGTGATCGT ATACCGGAGA AACTGCCGGG ACTTCGACAC GGACATCACC 
GACTCCTCTG CGGCCCTCAC TGGTGGCTTC CACCCTGTCA ACTTCAAGAC TGCAAGGCCC 
AACAACCCGC AGCTCCTGCA CCCGTCCGCC CCTCCAGACC TAACGGCCAG TGCTGGCATC 
TACCGCGGGC CTGTGTATGC CCTGCAGGAC TCCGCCGACA AGATCCCCAT GACTAATTCG 
CCCCTGCTGG ATCCCCTGCC CAGCCTCAAG ATCAAGGTCT ATAACTCCAG CACCATCGGT 
TCTGGGTCTG GCCTGGCTGA TGGAGCCGAC CTGCTGGGTG TCCTCCCGCC GGGCACGTAC 
CCAGGCGATT TCTCCCGGGA CACCCATTTC CTGCACCTGC GCAGTGCCAG CCTTGGTTCC 
CAGCACCTCC TGGGCCTACC TCGGGACCCC AGCAGCAGTG TCAGCGGCAC CTTTGGTTGC 
CTGGGAGGAA GGCTGAGCCT CCCCGGCACA GGGGTCAGCC TGTTGGTACC AAATGGAGCC 
ATTCCCCAGG GCAAGTTCTA TGACCTGTAT CTACATATCA ACAAGGCCGA AAGCACCCTC 
CCACTTTCAG AAGGTTCCCA GACAGTATTG AGCCCCTCGG TGACCTGTGG GCCCACAGGC 
CTACTCCTGT GCCGCCCTGT CGTCCTCACC GTGCCCCACT GTGCTGAAGT CATCGCTGGA 
GACTGGATCT TTCAGCTCAA GACCCAGGCC CATCAGGGCC ACTGGGAGGA GGTGGTGACC 
TTGGATGAGG AGACCCTCAA CACACCCTGC TACTGCCAGC TGGAGGCTAA GTCCTGCCAC 
ATCCTGCTGG ACCAGCTGGG TACCTACGTA TTCATGGGCG AGTCCTACTC TCGCTCTGCA 
GTCAAGCGGC TCCAGCTGGC CATCTTCGCC CCAGCCCTCT GCACCTCCCT GGAGTATAGC 
CTCAGGGTCT ACTGTCTGGA GGACACACCT GTAGCACTGA AGGAGGTCCT GGAGCTGGAG 
AGGACTCTGG GTGGCTACTT GGTGGAGGAG CCCAAGCCTT TGCTCTTTAA GGACAGTTAC 
CACAACCTAC GCCTCTCCCT CCATGACATC CCCCATGCCC ACTGGAGGAG CAAACTACTG 
GCCAAGTACC AGGAGATTCC CTTCTACCAC GTCTGGAATG GCAGCCAGAG AGCCCTGCAC 
TGCACTTTCA CCCTGGAGAG GCATAGCCTG GCCTCCACGG AGTTCACCTG TAAGGTCTGC 
GTGCGGCAGG TCGAAGGGGA AGGCCAGATT TTCCAGCTGC ACACAACGTT GGCCGAGACG 
CCTGCTGGCT CCCTGGATGC TCTCTGCTCT GCCCCGGGCA ATGCCATCAC CACCCAGCTG 
GGACCCTATG CCTTCAAGAT ACCCCTGTCC ATCCGCCAAA AGATCTGCAG CAGCCTGGAC 
GCCCCCAACT CCCGGGGCAA CGACTGGAGG CTGTTGGCGC AGAAGCTGTC CATGGACCGG 
TACCTAAACT ACTTCGCCAC CAAAGCTAGT CCCACAGGTG TCATCTTAGA CCTCTGGGAA 
GCTCGGCAAC AGGATGACGG GGACCTCAAC AGCCTGGCCA GTGCCTTGGA GGAGATGGGC 
AAGAGTGAGA TGCTGGTAGC CATGGCCACA GATGGCGATT GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Unc5b ( NM_029770.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084046.2 Mus musculus unc-5 netrin receptor B (Unc5b), mRNA.

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CloneID	OMu18210
Clone ID Related Accession (Same CDS sequence)	NM_029770.2 , NM_029770.3
Accession Version	NM_029770.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2838bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-27
Organism	Mus musculus(House mouse)
Product	netrin receptor UNC5B precursor
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK154271.1, AK154287.1, BY529391.1 and BY521726.1. On Jan 28, 2006 this sequence version replaced NM_029770.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK154271.1, AK154287.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END##

ATGAGGGCCC GGAGCGGGGT GCGGAGCGCG CTGCTGCTGG CGCTGCTGCT TTGCTGGGAT 
CCGACACCGA GCCTAGCAGG CGTTGACTCT GCTGGCCAGG TGCTCCCAGA CTCCTACCCA 
TCAGCCCCTG CGGAGCAGCT GCCGTACTTC CTATTGGAGC CACAGGACGC CTACATCGTA 
AAGAACAAGC CAGTGGAACT GCACTGCAGA GCCTTCCCTG CCACGCAGAT CTACTTCAAG 
TGTAATGGCG AGTGGGTCAG CCAGAATGAC CACGTCACAC AGGAGAGCCT GGATGAGGCC 
ACAGGCTTGC GGGTGCGAGA GGTGCAGATC GAGGTGTCAC GGCAGCAAGT GGAGGAACTC 
TTCGGGCTCG AGGACTACTG GTGCCAGTGC GTGGCCTGGA GCTCTTCGGG AACTACCAAG 
AGTCGCCGAG CCTACATCCG CATTGCCTAC TTGCGCAAGA ACTTTGACCA GGAGCCTCTG 
GCCAAGGAGG TACCCTTGGA TCATGAGGTC CTTCTGCAGT GCCGCCCACC GGAGGGAGTG 
CCTGTGGCTG AGGTGGAATG GCTCAAGAAT GAAGATGTCA TTGACCCCGC TCAGGACACT 
AACTTCCTGC TCACCATTGA CCACAACCTC ATCATCCGCC AGGCGCGCCT CTCAGACACG 
GCCAACTACA CCTGTGTGGC CAAGAATATC GTGGCCAAGC GCCGGAGCAC CACGGCCACA 
GTCATCGTCT ATGTGAATGG AGGCTGGTCC AGCTGGGCAG AGTGGTCACC CTGTTCCAAT 
CGCTGTGGCC GAGGCTGGCA GAAGCGTACT CGGACCTGCA CCAATCCAGC CCCACTCAAT 
GGAGGCGCCT TCTGTGAGGG ACAGGCCTTC CAGAAGACAG CTTGCACCAC CGTGTGCCCA 
GTGGATGGAG CGTGGACCGA GTGGAGCAAG TGGTCTGCCT GCAGCACAGA GTGTGCGCAC 
TGGCGCAGCC GCGAGTGCAT GGCACCGCCA CCCCAGAACG GAGGCCGTGA CTGCAGCGGG 
ACGCTACTTG ACTCCAAGAA CTGCACTGAT GGGCTGTGCG TGCTGAATCA GAGAACTCTA 
AACGACCCTA AAAGCCACCC CCTGGAGACA TCGGGAGATG TGGCACTGTA CGCAGGCCTT 
GTGGTGGCCG TCTTTGTGGT GGTAGCGGTT CTCATGGCCG TGGGAGTGAT CGTATACCGG 
AGAAACTGCC GGGACTTCGA CACGGACATC ACCGACTCCT CTGCGGCCCT CACTGGTGGC 
TTCCACCCTG TCAACTTCAA GACTGCAAGG CCCAACAACC CGCAGCTCCT GCACCCGTCC 
GCCCCTCCAG ACCTAACGGC CAGTGCTGGC ATCTACCGCG GGCCTGTGTA TGCCCTGCAG 
GACTCCGCCG ACAAGATCCC CATGACTAAT TCGCCCCTGC TGGATCCCCT GCCCAGCCTC 
AAGATCAAGG TCTATAACTC CAGCACCATC GGTTCTGGGT CTGGCCTGGC TGATGGAGCC 
GACCTGCTGG GTGTCCTCCC GCCGGGCACG TACCCAGGCG ATTTCTCCCG GGACACCCAT 
TTCCTGCACC TGCGCAGTGC CAGCCTTGGT TCCCAGCACC TCCTGGGCCT ACCTCGGGAC 
CCCAGCAGCA GTGTCAGCGG CACCTTTGGT TGCCTGGGAG GAAGGCTGAG CCTCCCCGGC 
ACAGGGGTCA GCCTGTTGGT ACCAAATGGA GCCATTCCCC AGGGCAAGTT CTATGACCTG 
TATCTACATA TCAACAAGGC CGAAAGCACC CTCCCACTTT CAGAAGGTTC CCAGACAGTA 
TTGAGCCCCT CGGTGACCTG TGGGCCCACA GGCCTACTCC TGTGCCGCCC TGTCGTCCTC 
ACCGTGCCCC ACTGTGCTGA AGTCATCGCT GGAGACTGGA TCTTTCAGCT CAAGACCCAG 
GCCCATCAGG GCCACTGGGA GGAGGTGGTG ACCTTGGATG AGGAGACCCT CAACACACCC 
TGCTACTGCC AGCTGGAGGC TAAGTCCTGC CACATCCTGC TGGACCAGCT GGGTACCTAC 
GTATTCATGG GCGAGTCCTA CTCTCGCTCT GCAGTCAAGC GGCTCCAGCT GGCCATCTTC 
GCCCCAGCCC TCTGCACCTC CCTGGAGTAT AGCCTCAGGG TCTACTGTCT GGAGGACACA 
CCTGTAGCAC TGAAGGAGGT CCTGGAGCTG GAGAGGACTC TGGGTGGCTA CTTGGTGGAG 
GAGCCCAAGC CTTTGCTCTT TAAGGACAGT TACCACAACC TACGCCTCTC CCTCCATGAC 
ATCCCCCATG CCCACTGGAG GAGCAAACTA CTGGCCAAGT ACCAGGAGAT TCCCTTCTAC 
CACGTCTGGA ATGGCAGCCA GAGAGCCCTG CACTGCACTT TCACCCTGGA GAGGCATAGC 
CTGGCCTCCA CGGAGTTCAC CTGTAAGGTC TGCGTGCGGC AGGTCGAAGG GGAAGGCCAG 
ATTTTCCAGC TGCACACAAC GTTGGCCGAG ACGCCTGCTG GCTCCCTGGA TGCTCTCTGC 
TCTGCCCCGG GCAATGCCAT CACCACCCAG CTGGGACCCT ATGCCTTCAA GATACCCCTG 
TCCATCCGCC AAAAGATCTG CAGCAGCCTG GACGCCCCCA ACTCCCGGGG CAACGACTGG 
AGGCTGTTGG CGCAGAAGCT GTCCATGGAC CGGTACCTAA ACTACTTCGC CACCAAAGCT 
AGTCCCACAG GTGTCATCTT AGACCTCTGG GAAGCTCGGC AACAGGATGA CGGGGACCTC 
AACAGCCTGG CCAGTGCCTT GGAGGAGATG GGCAAGAGTG AGATGCTGGT AGCCATGGCC 
ACAGATGGCG ATTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084046.2
CDS	417..3254
Translation	MRARSGVRSALLLALLLCWDPTPSLAGVDSAGQVLPDSYPSAPAEQLPYFLLEPQDAYIVKNKPVELHCRAFPATQIYFKCNGEWVSQNDHVTQESLDEATGLRVREVQIEVSRQQVEELFGLEDYWCQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLNQRTLNDPKSHPLETSGDVALYAGLVVAVFVVVAVLMAVGVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPNNPQLLHPSAPPDLTASAGIYRGPVYALQDSADKIPMTNSPLLDPLPSLKIKVYNSSTIGSGSGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFMGESYSRSAVKRLQLAIFAPALCTSLEYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQRALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETPAGSLDALCSAPGNAITTQLGPYAFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATDGDC

Target ORF information:

RefSeq Version	NM_029770.2
Organism	Mus musculus(House mouse)
Definition	Mus musculus unc-5 netrin receptor B (Unc5b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029770.2

ORF Insert Sequence:

ATGAGGGCCC GGAGCGGGGT GCGGAGCGCG CTGCTGCTGG CGCTGCTGCT TTGCTGGGAT 
CCGACACCGA GCCTAGCAGG CGTTGACTCT GCTGGCCAGG TGCTCCCAGA CTCCTACCCA 
TCAGCCCCTG CGGAGCAGCT GCCGTACTTC CTATTGGAGC CACAGGACGC CTACATCGTA 
AAGAACAAGC CAGTGGAACT GCACTGCAGA GCCTTCCCTG CCACGCAGAT CTACTTCAAG 
TGTAATGGCG AGTGGGTCAG CCAGAATGAC CACGTCACAC AGGAGAGCCT GGATGAGGCC 
ACAGGCTTGC GGGTGCGAGA GGTGCAGATC GAGGTGTCAC GGCAGCAAGT GGAGGAACTC 
TTCGGGCTCG AGGACTACTG GTGCCAGTGC GTGGCCTGGA GCTCTTCGGG AACTACCAAG 
AGTCGCCGAG CCTACATCCG CATTGCCTAC TTGCGCAAGA ACTTTGACCA GGAGCCTCTG 
GCCAAGGAGG TACCCTTGGA TCATGAGGTC CTTCTGCAGT GCCGCCCACC GGAGGGAGTG 
CCTGTGGCTG AGGTGGAATG GCTCAAGAAT GAAGATGTCA TTGACCCCGC TCAGGACACT 
AACTTCCTGC TCACCATTGA CCACAACCTC ATCATCCGCC AGGCGCGCCT CTCAGACACG 
GCCAACTACA CCTGTGTGGC CAAGAATATC GTGGCCAAGC GCCGGAGCAC CACGGCCACA 
GTCATCGTCT ATGTGAATGG AGGCTGGTCC AGCTGGGCAG AGTGGTCACC CTGTTCCAAT 
CGCTGTGGCC GAGGCTGGCA GAAGCGTACT CGGACCTGCA CCAATCCAGC CCCACTCAAT 
GGAGGCGCCT TCTGTGAGGG ACAGGCCTTC CAGAAGACAG CTTGCACCAC CGTGTGCCCA 
GTGGATGGAG CGTGGACCGA GTGGAGCAAG TGGTCTGCCT GCAGCACAGA GTGTGCGCAC 
TGGCGCAGCC GCGAGTGCAT GGCACCGCCA CCCCAGAACG GAGGCCGTGA CTGCAGCGGG 
ACGCTACTTG ACTCCAAGAA CTGCACTGAT GGGCTGTGCG TGCTGAATCA GAGAACTCTA 
AACGACCCTA AAAGCCACCC CCTGGAGACA TCGGGAGATG TGGCACTGTA CGCAGGCCTT 
GTGGTGGCCG TCTTTGTGGT GGTAGCGGTT CTCATGGCCG TGGGAGTGAT CGTATACCGG 
AGAAACTGCC GGGACTTCGA CACGGACATC ACCGACTCCT CTGCGGCCCT CACTGGTGGC 
TTCCACCCTG TCAACTTCAA GACTGCAAGG CCCAACAACC CGCAGCTCCT GCACCCGTCC 
GCCCCTCCAG ACCTAACGGC CAGTGCTGGC ATCTACCGCG GGCCTGTGTA TGCCCTGCAG 
GACTCCGCCG ACAAGATCCC CATGACTAAT TCGCCCCTGC TGGATCCCCT GCCCAGCCTC 
AAGATCAAGG TCTATAACTC CAGCACCATC GGTTCTGGGT CTGGCCTGGC TGATGGAGCC 
GACCTGCTGG GTGTCCTCCC GCCGGGCACG TACCCAGGCG ATTTCTCCCG GGACACCCAT 
TTCCTGCACC TGCGCAGTGC CAGCCTTGGT TCCCAGCACC TCCTGGGCCT ACCTCGGGAC 
CCCAGCAGCA GTGTCAGCGG CACCTTTGGT TGCCTGGGAG GAAGGCTGAG CCTCCCCGGC 
ACAGGGGTCA GCCTGTTGGT ACCAAATGGA GCCATTCCCC AGGGCAAGTT CTATGACCTG 
TATCTACATA TCAACAAGGC CGAAAGCACC CTCCCACTTT CAGAAGGTTC CCAGACAGTA 
TTGAGCCCCT CGGTGACCTG TGGGCCCACA GGCCTACTCC TGTGCCGCCC TGTCGTCCTC 
ACCGTGCCCC ACTGTGCTGA AGTCATCGCT GGAGACTGGA TCTTTCAGCT CAAGACCCAG 
GCCCATCAGG GCCACTGGGA GGAGGTGGTG ACCTTGGATG AGGAGACCCT CAACACACCC 
TGCTACTGCC AGCTGGAGGC TAAGTCCTGC CACATCCTGC TGGACCAGCT GGGTACCTAC 
GTATTCATGG GCGAGTCCTA CTCTCGCTCT GCAGTCAAGC GGCTCCAGCT GGCCATCTTC 
GCCCCAGCCC TCTGCACCTC CCTGGAGTAT AGCCTCAGGG TCTACTGTCT GGAGGACACA 
CCTGTAGCAC TGAAGGAGGT CCTGGAGCTG GAGAGGACTC TGGGTGGCTA CTTGGTGGAG 
GAGCCCAAGC CTTTGCTCTT TAAGGACAGT TACCACAACC TACGCCTCTC CCTCCATGAC 
ATCCCCCATG CCCACTGGAG GAGCAAACTA CTGGCCAAGT ACCAGGAGAT TCCCTTCTAC 
CACGTCTGGA ATGGCAGCCA GAGAGCCCTG CACTGCACTT TCACCCTGGA GAGGCATAGC 
CTGGCCTCCA CGGAGTTCAC CTGTAAGGTC TGCGTGCGGC AGGTCGAAGG GGAAGGCCAG 
ATTTTCCAGC TGCACACAAC GTTGGCCGAG ACGCCTGCTG GCTCCCTGGA TGCTCTCTGC 
TCTGCCCCGG GCAATGCCAT CACCACCCAG CTGGGACCCT ATGCCTTCAA GATACCCCTG 
TCCATCCGCC AAAAGATCTG CAGCAGCCTG GACGCCCCCA ACTCCCGGGG CAACGACTGG 
AGGCTGTTGG CGCAGAAGCT GTCCATGGAC CGGTACCTAA ACTACTTCGC CACCAAAGCT 
AGTCCCACAG GTGTCATCTT AGACCTCTGG GAAGCTCGGC AACAGGATGA CGGGGACCTC 
AACAGCCTGG CCAGTGCCTT GGAGGAGATG GGCAAGAGTG AGATGCTGGT AGCCATGGCC 
ACAGATGGCG ATTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Unc5b ( NM_029770.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_084046.2 Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OMu18210
Clone ID Related Accession (Same CDS sequence)	NM_029770.2 , NM_029770.3
Accession Version	NM_029770.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2838bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-07
Organism	Mus musculus(house mouse)
Product	netrin receptor UNC5B isoform 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK018177.1, AK158284.1, BC048162.1, AK147603.1 and AW488068.1. On Dec 30, 2017 this sequence version replaced NM_029770.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK154271.1, AK154287.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGGGCCC GGAGCGGGGT GCGGAGCGCG CTGCTGCTGG CGCTGCTGCT TTGCTGGGAT 
CCGACACCGA GCCTAGCAGG CGTTGACTCT GCTGGCCAGG TGCTCCCAGA CTCCTACCCA 
TCAGCCCCTG CGGAGCAGCT GCCGTACTTC CTATTGGAGC CACAGGACGC CTACATCGTA 
AAGAACAAGC CAGTGGAACT GCACTGCAGA GCCTTCCCTG CCACGCAGAT CTACTTCAAG 
TGTAATGGCG AGTGGGTCAG CCAGAATGAC CACGTCACAC AGGAGAGCCT GGATGAGGCC 
ACAGGCTTGC GGGTGCGAGA GGTGCAGATC GAGGTGTCAC GGCAGCAAGT GGAGGAACTC 
TTCGGGCTCG AGGACTACTG GTGCCAGTGC GTGGCCTGGA GCTCTTCGGG AACTACCAAG 
AGTCGCCGAG CCTACATCCG CATTGCCTAC TTGCGCAAGA ACTTTGACCA GGAGCCTCTG 
GCCAAGGAGG TACCCTTGGA TCATGAGGTC CTTCTGCAGT GCCGCCCACC GGAGGGAGTG 
CCTGTGGCTG AGGTGGAATG GCTCAAGAAT GAAGATGTCA TTGACCCCGC TCAGGACACT 
AACTTCCTGC TCACCATTGA CCACAACCTC ATCATCCGCC AGGCGCGCCT CTCAGACACG 
GCCAACTACA CCTGTGTGGC CAAGAATATC GTGGCCAAGC GCCGGAGCAC CACGGCCACA 
GTCATCGTCT ATGTGAATGG AGGCTGGTCC AGCTGGGCAG AGTGGTCACC CTGTTCCAAT 
CGCTGTGGCC GAGGCTGGCA GAAGCGTACT CGGACCTGCA CCAATCCAGC CCCACTCAAT 
GGAGGCGCCT TCTGTGAGGG ACAGGCCTTC CAGAAGACAG CTTGCACCAC CGTGTGCCCA 
GTGGATGGAG CGTGGACCGA GTGGAGCAAG TGGTCTGCCT GCAGCACAGA GTGTGCGCAC 
TGGCGCAGCC GCGAGTGCAT GGCACCGCCA CCCCAGAACG GAGGCCGTGA CTGCAGCGGG 
ACGCTACTTG ACTCCAAGAA CTGCACTGAT GGGCTGTGCG TGCTGAATCA GAGAACTCTA 
AACGACCCTA AAAGCCACCC CCTGGAGACA TCGGGAGATG TGGCACTGTA CGCAGGCCTT 
GTGGTGGCCG TCTTTGTGGT GGTAGCGGTT CTCATGGCCG TGGGAGTGAT CGTATACCGG 
AGAAACTGCC GGGACTTCGA CACGGACATC ACCGACTCCT CTGCGGCCCT CACTGGTGGC 
TTCCACCCTG TCAACTTCAA GACTGCAAGG CCCAACAACC CGCAGCTCCT GCACCCGTCC 
GCCCCTCCAG ACCTAACGGC CAGTGCTGGC ATCTACCGCG GGCCTGTGTA TGCCCTGCAG 
GACTCCGCCG ACAAGATCCC CATGACTAAT TCGCCCCTGC TGGATCCCCT GCCCAGCCTC 
AAGATCAAGG TCTATAACTC CAGCACCATC GGTTCTGGGT CTGGCCTGGC TGATGGAGCC 
GACCTGCTGG GTGTCCTCCC GCCGGGCACG TACCCAGGCG ATTTCTCCCG GGACACCCAT 
TTCCTGCACC TGCGCAGTGC CAGCCTTGGT TCCCAGCACC TCCTGGGCCT ACCTCGGGAC 
CCCAGCAGCA GTGTCAGCGG CACCTTTGGT TGCCTGGGAG GAAGGCTGAG CCTCCCCGGC 
ACAGGGGTCA GCCTGTTGGT ACCAAATGGA GCCATTCCCC AGGGCAAGTT CTATGACCTG 
TATCTACATA TCAACAAGGC CGAAAGCACC CTCCCACTTT CAGAAGGTTC CCAGACAGTA 
TTGAGCCCCT CGGTGACCTG TGGGCCCACA GGCCTACTCC TGTGCCGCCC TGTCGTCCTC 
ACCGTGCCCC ACTGTGCTGA AGTCATCGCT GGAGACTGGA TCTTTCAGCT CAAGACCCAG 
GCCCATCAGG GCCACTGGGA GGAGGTGGTG ACCTTGGATG AGGAGACCCT CAACACACCC 
TGCTACTGCC AGCTGGAGGC TAAGTCCTGC CACATCCTGC TGGACCAGCT GGGTACCTAC 
GTATTCATGG GCGAGTCCTA CTCTCGCTCT GCAGTCAAGC GGCTCCAGCT GGCCATCTTC 
GCCCCAGCCC TCTGCACCTC CCTGGAGTAT AGCCTCAGGG TCTACTGTCT GGAGGACACA 
CCTGTAGCAC TGAAGGAGGT CCTGGAGCTG GAGAGGACTC TGGGTGGCTA CTTGGTGGAG 
GAGCCCAAGC CTTTGCTCTT TAAGGACAGT TACCACAACC TACGCCTCTC CCTCCATGAC 
ATCCCCCATG CCCACTGGAG GAGCAAACTA CTGGCCAAGT ACCAGGAGAT TCCCTTCTAC 
CACGTCTGGA ATGGCAGCCA GAGAGCCCTG CACTGCACTT TCACCCTGGA GAGGCATAGC 
CTGGCCTCCA CGGAGTTCAC CTGTAAGGTC TGCGTGCGGC AGGTCGAAGG GGAAGGCCAG 
ATTTTCCAGC TGCACACAAC GTTGGCCGAG ACGCCTGCTG GCTCCCTGGA TGCTCTCTGC 
TCTGCCCCGG GCAATGCCAT CACCACCCAG CTGGGACCCT ATGCCTTCAA GATACCCCTG 
TCCATCCGCC AAAAGATCTG CAGCAGCCTG GACGCCCCCA ACTCCCGGGG CAACGACTGG 
AGGCTGTTGG CGCAGAAGCT GTCCATGGAC CGGTACCTAA ACTACTTCGC CACCAAAGCT 
AGTCCCACAG GTGTCATCTT AGACCTCTGG GAAGCTCGGC AACAGGATGA CGGGGACCTC 
AACAGCCTGG CCAGTGCCTT GGAGGAGATG GGCAAGAGTG AGATGCTGGT AGCCATGGCC 
ACAGATGGCG ATTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_084046.2
CDS	417..3254
Translation	MRARSGVRSALLLALLLCWDPTPSLAGVDSAGQVLPDSYPSAPAEQLPYFLLEPQDAYIVKNKPVELHCRAFPATQIYFKCNGEWVSQNDHVTQESLDEATGLRVREVQIEVSRQQVEELFGLEDYWCQCVAWSSSGTTKSRRAYIRIAYLRKNFDQEPLAKEVPLDHEVLLQCRPPEGVPVAEVEWLKNEDVIDPAQDTNFLLTIDHNLIIRQARLSDTANYTCVAKNIVAKRRSTTATVIVYVNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACTTVCPVDGAWTEWSKWSACSTECAHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCVLNQRTLNDPKSHPLETSGDVALYAGLVVAVFVVVAVLMAVGVIVYRRNCRDFDTDITDSSAALTGGFHPVNFKTARPNNPQLLHPSAPPDLTASAGIYRGPVYALQDSADKIPMTNSPLLDPLPSLKIKVYNSSTIGSGSGLADGADLLGVLPPGTYPGDFSRDTHFLHLRSASLGSQHLLGLPRDPSSSVSGTFGCLGGRLSLPGTGVSLLVPNGAIPQGKFYDLYLHINKAESTLPLSEGSQTVLSPSVTCGPTGLLLCRPVVLTVPHCAEVIAGDWIFQLKTQAHQGHWEEVVTLDEETLNTPCYCQLEAKSCHILLDQLGTYVFMGESYSRSAVKRLQLAIFAPALCTSLEYSLRVYCLEDTPVALKEVLELERTLGGYLVEEPKPLLFKDSYHNLRLSLHDIPHAHWRSKLLAKYQEIPFYHVWNGSQRALHCTFTLERHSLASTEFTCKVCVRQVEGEGQIFQLHTTLAETPAGSLDALCSAPGNAITTQLGPYAFKIPLSIRQKICSSLDAPNSRGNDWRLLAQKLSMDRYLNYFATKASPTGVILDLWEARQQDDGDLNSLASALEEMGKSEMLVAMATDGDC

Target ORF information:

RefSeq Version	NM_029770.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus unc-5 netrin receptor B (Unc5b), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_029770.3

ORF Insert Sequence:

ATGAGGGCCC GGAGCGGGGT GCGGAGCGCG CTGCTGCTGG CGCTGCTGCT TTGCTGGGAT 
CCGACACCGA GCCTAGCAGG CGTTGACTCT GCTGGCCAGG TGCTCCCAGA CTCCTACCCA 
TCAGCCCCTG CGGAGCAGCT GCCGTACTTC CTATTGGAGC CACAGGACGC CTACATCGTA 
AAGAACAAGC CAGTGGAACT GCACTGCAGA GCCTTCCCTG CCACGCAGAT CTACTTCAAG 
TGTAATGGCG AGTGGGTCAG CCAGAATGAC CACGTCACAC AGGAGAGCCT GGATGAGGCC 
ACAGGCTTGC GGGTGCGAGA GGTGCAGATC GAGGTGTCAC GGCAGCAAGT GGAGGAACTC 
TTCGGGCTCG AGGACTACTG GTGCCAGTGC GTGGCCTGGA GCTCTTCGGG AACTACCAAG 
AGTCGCCGAG CCTACATCCG CATTGCCTAC TTGCGCAAGA ACTTTGACCA GGAGCCTCTG 
GCCAAGGAGG TACCCTTGGA TCATGAGGTC CTTCTGCAGT GCCGCCCACC GGAGGGAGTG 
CCTGTGGCTG AGGTGGAATG GCTCAAGAAT GAAGATGTCA TTGACCCCGC TCAGGACACT 
AACTTCCTGC TCACCATTGA CCACAACCTC ATCATCCGCC AGGCGCGCCT CTCAGACACG 
GCCAACTACA CCTGTGTGGC CAAGAATATC GTGGCCAAGC GCCGGAGCAC CACGGCCACA 
GTCATCGTCT ATGTGAATGG AGGCTGGTCC AGCTGGGCAG AGTGGTCACC CTGTTCCAAT 
CGCTGTGGCC GAGGCTGGCA GAAGCGTACT CGGACCTGCA CCAATCCAGC CCCACTCAAT 
GGAGGCGCCT TCTGTGAGGG ACAGGCCTTC CAGAAGACAG CTTGCACCAC CGTGTGCCCA 
GTGGATGGAG CGTGGACCGA GTGGAGCAAG TGGTCTGCCT GCAGCACAGA GTGTGCGCAC 
TGGCGCAGCC GCGAGTGCAT GGCACCGCCA CCCCAGAACG GAGGCCGTGA CTGCAGCGGG 
ACGCTACTTG ACTCCAAGAA CTGCACTGAT GGGCTGTGCG TGCTGAATCA GAGAACTCTA 
AACGACCCTA AAAGCCACCC CCTGGAGACA TCGGGAGATG TGGCACTGTA CGCAGGCCTT 
GTGGTGGCCG TCTTTGTGGT GGTAGCGGTT CTCATGGCCG TGGGAGTGAT CGTATACCGG 
AGAAACTGCC GGGACTTCGA CACGGACATC ACCGACTCCT CTGCGGCCCT CACTGGTGGC 
TTCCACCCTG TCAACTTCAA GACTGCAAGG CCCAACAACC CGCAGCTCCT GCACCCGTCC 
GCCCCTCCAG ACCTAACGGC CAGTGCTGGC ATCTACCGCG GGCCTGTGTA TGCCCTGCAG 
GACTCCGCCG ACAAGATCCC CATGACTAAT TCGCCCCTGC TGGATCCCCT GCCCAGCCTC 
AAGATCAAGG TCTATAACTC CAGCACCATC GGTTCTGGGT CTGGCCTGGC TGATGGAGCC 
GACCTGCTGG GTGTCCTCCC GCCGGGCACG TACCCAGGCG ATTTCTCCCG GGACACCCAT 
TTCCTGCACC TGCGCAGTGC CAGCCTTGGT TCCCAGCACC TCCTGGGCCT ACCTCGGGAC 
CCCAGCAGCA GTGTCAGCGG CACCTTTGGT TGCCTGGGAG GAAGGCTGAG CCTCCCCGGC 
ACAGGGGTCA GCCTGTTGGT ACCAAATGGA GCCATTCCCC AGGGCAAGTT CTATGACCTG 
TATCTACATA TCAACAAGGC CGAAAGCACC CTCCCACTTT CAGAAGGTTC CCAGACAGTA 
TTGAGCCCCT CGGTGACCTG TGGGCCCACA GGCCTACTCC TGTGCCGCCC TGTCGTCCTC 
ACCGTGCCCC ACTGTGCTGA AGTCATCGCT GGAGACTGGA TCTTTCAGCT CAAGACCCAG 
GCCCATCAGG GCCACTGGGA GGAGGTGGTG ACCTTGGATG AGGAGACCCT CAACACACCC 
TGCTACTGCC AGCTGGAGGC TAAGTCCTGC CACATCCTGC TGGACCAGCT GGGTACCTAC 
GTATTCATGG GCGAGTCCTA CTCTCGCTCT GCAGTCAAGC GGCTCCAGCT GGCCATCTTC 
GCCCCAGCCC TCTGCACCTC CCTGGAGTAT AGCCTCAGGG TCTACTGTCT GGAGGACACA 
CCTGTAGCAC TGAAGGAGGT CCTGGAGCTG GAGAGGACTC TGGGTGGCTA CTTGGTGGAG 
GAGCCCAAGC CTTTGCTCTT TAAGGACAGT TACCACAACC TACGCCTCTC CCTCCATGAC 
ATCCCCCATG CCCACTGGAG GAGCAAACTA CTGGCCAAGT ACCAGGAGAT TCCCTTCTAC 
CACGTCTGGA ATGGCAGCCA GAGAGCCCTG CACTGCACTT TCACCCTGGA GAGGCATAGC 
CTGGCCTCCA CGGAGTTCAC CTGTAAGGTC TGCGTGCGGC AGGTCGAAGG GGAAGGCCAG 
ATTTTCCAGC TGCACACAAC GTTGGCCGAG ACGCCTGCTG GCTCCCTGGA TGCTCTCTGC 
TCTGCCCCGG GCAATGCCAT CACCACCCAG CTGGGACCCT ATGCCTTCAA GATACCCCTG 
TCCATCCGCC AAAAGATCTG CAGCAGCCTG GACGCCCCCA ACTCCCGGGG CAACGACTGG 
AGGCTGTTGG CGCAGAAGCT GTCCATGGAC CGGTACCTAA ACTACTTCGC CACCAAAGCT 
AGTCCCACAG GTGTCATCTT AGACCTCTGG GAAGCTCGGC AACAGGATGA CGGGGACCTC 
AACAGCCTGG CCAGTGCCTT GGAGGAGATG GGCAAGAGTG AGATGCTGGT AGCCATGGCC 
ACAGATGGCG ATTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling.
Development (Cambridge, England)144(13)2392-2401(2017 07)
Tai-Nagara I,Yoshikawa Y,Numata N,Ando T,Okabe K,Sugiura Y,Ieda M,Takakura N,Nakagawa O,Zhou B,Okabayashi K,Suematsu M,Kitagawa Y,Bastmeyer M,Sato K,Klein R,Navankasattusas S,Li DY,Yamagishi S,Kubota Y

Unc-5 homolog B (UNC5B) is one of the key downstream targets of N-?-Acetyltransferase 10 (Naa10).
Scientific reports638508(2016 Dec)
Xu H,Han Y,Liu B,Li R

Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology30(11)3835-3844(2016 11)
Mediero A,Wilder T,Ramkhelawon B,Moore KJ,Cronstein BN

Structural Decoding of the Netrin-1/UNC5 Interaction and its Therapeutical Implications in Cancers.
Cancer cell29(2)173-85(2016 Feb)
Grandin M,Meier M,Delcros JG,Nikodemus D,Reuten R,Patel TR,Goldschneider D,Orriss G,Krahn N,Boussouar A,Abes R,Dean Y,Neves D,Bernet A,Depil S,Schneiders F,Poole K,Dante R,Koch M,Mehlen P,Stetefeld J

Widespread Differential Expression of Coding Region and 3' UTR Sequences in Neurons and Other Tissues.
Neuron88(6)1149-56(2015 Dec)
Kocabas A,Duarte T,Kumar S,Hynes MA

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Unc5b cDNA ORF clone, Mus musculus(house mouse)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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